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Items: 22

1.

Novel orally active inhibitors of β-1,3-glucan synthesis derived from enfumafungin.

Apgar JM, Wilkening RR, Greenlee ML, Balkovec JM, Flattery AM, Abruzzo GK, Galgoci AM, Giacobbe RA, Gill CJ, Hsu MJ, Liberator P, Misura AS, Motyl M, Nielsen Kahn J, Powles M, Racine F, Dragovic J, Habulihaz B, Fan W, Kirwan R, Lee S, Liu H, Mamai A, Nelson K, Peel M.

Bioorg Med Chem Lett. 2015 Dec 15;25(24):5813-8. doi: 10.1016/j.bmcl.2015.10.011. Epub 2015 Oct 9.

PMID:
26542966
2.

Comparison of lipoprotein separation and lipid analysis methodologies for human and cynomolgus monkey plasma samples.

Han S, Flattery AM, McLaren D, Raubertas R, Lee SH, Mendoza V, Rosa R, Geoghagen N, Castro-Perez JM, Roddy TP, Forrest G, Johns D, Hubbard BK, Li J.

J Cardiovasc Transl Res. 2012 Feb;5(1):75-83. doi: 10.1007/s12265-011-9340-9. Epub 2011 Dec 23.

PMID:
22194019
3.

A rapid method for cross-species quantitation of apolipoproteins A1, B48 and B100 in plasma by ultra-performance liquid chromatography/tandem mass spectrometry.

Lassman ME, McLaughlin TM, Somers EP, Stefanni AC, Chen Z, Murphy BA, Bierilo KK, Flattery AM, Wong KK, Castro-Perez JM, Hubbard BK, Roddy TP.

Rapid Commun Mass Spectrom. 2012 Jan 30;26(2):101-8. doi: 10.1002/rcm.5296.

PMID:
22173797
4.

Chronic antagonism of the mineralocorticoid receptor ameliorates hypertension and end organ damage in a rodent model of salt-sensitive hypertension.

Zhou X, Crook MF, Sharif-Rodriguez W, Zhu Y, Ruben Z, Pan Y, Urosevic-Price O, Wang L, Flattery AM, Forrest G, Szeto D, Zhao H, Roy S, Forrest MJ.

Clin Exp Hypertens. 2011;33(8):538-47. doi: 10.3109/10641963.2011.566956. Epub 2011 Sep 27.

5.

Efficacy of caspofungin in a juvenile mouse model of central nervous system candidiasis.

Flattery AM, Hickey E, Gill CJ, Powles MA, Misura AS, Galgoci AM, Ellis JD, Zhang R, Sandhu P, Ronan J, Abruzzo GK.

Antimicrob Agents Chemother. 2011 Jul;55(7):3491-7. doi: 10.1128/AAC.01328-10. Epub 2011 Apr 25.

6.

Validation of human ApoB and ApoAI immunoturbidity assays for non-human primate dyslipidemia and atherosclerosis research.

Chen Z, Strack AM, Stefanni AC, Chen Y, Wu W, Pan Y, Urosevic-Price O, Wang L, McLaughlin T, Geoghagen N, Lassman ME, Roddy TP, Wong KK, Hubbard BK, Flattery AM.

J Cardiovasc Transl Res. 2011 Jun;4(3):373-83. doi: 10.1007/s12265-011-9264-4. Epub 2011 Mar 11.

PMID:
21394531
7.

In vivo efficacy of a novel oxazolidinone compound in two mouse models of infection.

Gill CJ, Abruzzo GK, Flattery AM, Misura AS, Bartizal K, Hickey EJ.

Antimicrob Agents Chemother. 2007 Sep;51(9):3434-6. Epub 2007 Jul 2.

8.

Efficacy of caspofungin against Aspergillus flavus, Aspergillus terreus, and Aspergillus nidulans.

Bowman JC, Abruzzo GK, Flattery AM, Gill CJ, Hickey EJ, Hsu MJ, Kahn JN, Liberator PA, Misura AS, Pelak BA, Wang TC, Douglas CM.

Antimicrob Agents Chemother. 2006 Dec;50(12):4202-5. Epub 2006 Oct 2.

9.

Arundifungin, a novel antifungal compound produced by fungi: biological activity and taxonomy of the producing organisms.

Cabello MA, Platas G, Collado J, Díez MT, Martín I, Vicente F, Meinz M, Onishi JC, Douglas C, Thompson J, Kurtz MB, Schwartz RE, Bills GF, Giacobbe RA, Abruzzo GK, Flattery AM, Kong L, Peláez F.

Int Microbiol. 2001 Jun;4(2):93-102.

PMID:
11770831
10.

Quantitative PCR assay to measure Aspergillus fumigatus burden in a murine model of disseminated aspergillosis: demonstration of efficacy of caspofungin acetate.

Bowman JC, Abruzzo GK, Anderson JW, Flattery AM, Gill CJ, Pikounis VB, Schmatz DM, Liberator PA, Douglas CM.

Antimicrob Agents Chemother. 2001 Dec;45(12):3474-81.

11.

The discovery of enfumafungin, a novel antifungal compound produced by an endophytic Hormonema species biological activity and taxonomy of the producing organisms.

Peláez F, Cabello A, Platas G, Díez MT, González del Val A, Basilio A, Martán I, Vicente F, Bills GE, Giacobbe RA, Schwartz RE, Onish JC, Meinz MS, Abruzzo GK, Flattery AM, Kong L, Kurtz MB.

Syst Appl Microbiol. 2000 Oct;23(3):333-43.

PMID:
11108011
12.

Efficacy of the echinocandin caspofungin against disseminated aspergillosis and candidiasis in cyclophosphamide-induced immunosuppressed mice.

Abruzzo GK, Gill CJ, Flattery AM, Kong L, Leighton C, Smith JG, Pikounis VB, Bartizal K, Rosen H.

Antimicrob Agents Chemother. 2000 Sep;44(9):2310-8.

13.

Rustmicin, a potent antifungal agent, inhibits sphingolipid synthesis at inositol phosphoceramide synthase.

Mandala SM, Thornton RA, Milligan J, Rosenbach M, Garcia-Calvo M, Bull HG, Harris G, Abruzzo GK, Flattery AM, Gill CJ, Bartizal K, Dreikorn S, Kurtz MB.

J Biol Chem. 1998 Jun 12;273(24):14942-9.

14.

Evaluation of the echinocandin antifungal MK-0991 (L-743,872): efficacies in mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis.

Abruzzo GK, Flattery AM, Gill CJ, Kong L, Smith JG, Pikounis VB, Balkovec JM, Bouffard AF, Dropinski JF, Rosen H, Kropp H, Bartizal K.

Antimicrob Agents Chemother. 1997 Nov;41(11):2333-8.

15.

In vitro preclinical evaluation studies with the echinocandin antifungal MK-0991 (L-743,872).

Bartizal K, Gill CJ, Abruzzo GK, Flattery AM, Kong L, Scott PM, Smith JG, Leighton CE, Bouffard A, Dropinski JF, Balkovec J.

Antimicrob Agents Chemother. 1997 Nov;41(11):2326-32.

16.

Evaluation of experimental therapeutics in a new mouse model of Helicobacter felis utilizing 16S rRNA polymerase chain reaction for detection.

Smith JG, Kong L, Abruzzo GK, Gill CJ, Flattery AM, Scott PM, Silver L, Kropp H, Bartizal K.

Scand J Gastroenterol. 1997 Apr;32(4):297-302.

PMID:
9140149
17.

New model of oropharyngeal and gastrointestinal colonization by Candida albicans in CD4+ T-cell-deficient mice for evaluation of antifungal agents.

Flattery AM, Abruzzo GK, Gill CJ, Smith JG, Bartizal K.

Antimicrob Agents Chemother. 1996 Jul;40(7):1604-9.

18.

A sensitive and specific PCR method to detect Helicobacter felis in a conventional mouse model.

Kong L, Smith JG, Bramhill D, Abruzzo GK, Bonfiglio C, Cioffe C, Flattery AM, Gill CJ, Lynch L, Scott PM, Silver L, Thompson C, Kropp H, Bartizal K.

Clin Diagn Lab Immunol. 1996 Jan;3(1):73-8.

19.

PCR detection of colonization by Helicobacter pylori in conventional, euthymic mice based on the 16S ribosomal gene sequence.

Smith JG, Kong L, Abruzzo GK, Gill CJ, Flattery AM, Scott PM, Bramhill D, Cioffe C, Thompson CM, Bartizal K.

Clin Diagn Lab Immunol. 1996 Jan;3(1):66-72.

20.

In vivo evaluation of three acid-stable azalide compounds, L-701,677, L-708,299 and L-708,365 compared to erythromycin, azithromycin and clarithromycin.

Gill CJ, Abruzzo GK, Flattery AM, Smith JG, Jackson J, Kong L, Wilkening R, Shankaran K, Kropp H, Bartizal K.

J Antibiot (Tokyo). 1995 Oct;48(10):1141-7.

21.

Evaluation of water-soluble pneumocandin analogs L-733560, L-705589, and L-731373 with mouse models of disseminated aspergillosis, candidiasis, and cryptococcosis.

Abruzzo GK, Flattery AM, Gill CJ, Kong L, Smith JG, Krupa D, Pikounis VB, Kropp H, Bartizal K.

Antimicrob Agents Chemother. 1995 May;39(5):1077-81.

22.

Use of anti-CD4+ hybridoma cells to induce Pneumocystis carinii in mice.

McFadden DC, Powles MA, Smith JG, Flattery AM, Bartizal K, Schmatz DM.

Infect Immun. 1994 Nov;62(11):4887-92.

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