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Items: 42

1.

Disruption of the NlpD lipoprotein of the plague pathogen Yersinia pestis affects iron acquisition and the activity of the twin-arginine translocation system.

Tidhar A, Levy Y, Zauberman A, Vagima Y, Gur D, Aftalion M, Israeli O, Chitlaru T, Ariel N, Flashner Y, Zvi A, Mamroud E.

PLoS Negl Trop Dis. 2019 Jun 6;13(6):e0007449. doi: 10.1371/journal.pntd.0007449. eCollection 2019 Jun.

2.

Adjunctive Corticosteroid Treatment Against Yersinia pestis Improves Bacterial Clearance, Immunopathology, and Survival in the Mouse Model of Bubonic Plague.

Levy Y, Vagima Y, Tidhar A, Zauberman A, Aftalion M, Gur D, Fogel I, Chitlaru T, Flashner Y, Mamroud E.

J Infect Dis. 2016 Sep 15;214(6):970-7. doi: 10.1093/infdis/jiw290. Epub 2016 Jul 11.

PMID:
27402776
3.

YopP-expressing variant of Y. pestis activates a potent innate immune response affording cross-protection against yersiniosis and tularemia [corrected].

Zauberman A, Flashner Y, Levy Y, Vagima Y, Tidhar A, Cohen O, Bar-Haim E, Gur D, Aftalion M, Halperin G, Shafferman A, Mamroud E.

PLoS One. 2013 Dec 16;8(12):e83560. doi: 10.1371/journal.pone.0083560. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/0ec1f217-4e7a-4dee-9a71-1076a3ac73f1.

4.

Early sensing of Yersinia pestis airway infection by bone marrow cells.

Vagima Y, Levy Y, Gur D, Tidhar A, Aftalion M, Abramovich H, Zahavy E, Zauberman A, Flashner Y, Shafferman A, Mamroud E.

Front Cell Infect Microbiol. 2012 Nov 26;2:143. doi: 10.3389/fcimb.2012.00143. eCollection 2012.

5.

T cells play an essential role in anti-F1 mediated rapid protection against bubonic plague.

Levy Y, Flashner Y, Tidhar A, Zauberman A, Aftalion M, Lazar S, Gur D, Shafferman A, Mamroud E.

Vaccine. 2011 Sep 16;29(40):6866-73. doi: 10.1016/j.vaccine.2011.07.059. Epub 2011 Jul 29.

PMID:
21803090
6.

The search for early markers of plague: evidence for accumulation of soluble Yersinia pestis LcrV in bubonic and pneumonic mouse models of disease.

Flashner Y, Fisher M, Tidhar A, Mechaly A, Gur D, Halperin G, Zahavy E, Mamroud E, Cohen S.

FEMS Immunol Med Microbiol. 2010 Jul 1;59(2):197-206. doi: 10.1111/j.1574-695X.2010.00687.x. Epub 2010 Apr 19.

7.

The NlpD lipoprotein is a novel Yersinia pestis virulence factor essential for the development of plague.

Tidhar A, Flashner Y, Cohen S, Levi Y, Zauberman A, Gur D, Aftalion M, Elhanany E, Zvi A, Shafferman A, Mamroud E.

PLoS One. 2009 Sep 14;4(9):e7023. doi: 10.1371/journal.pone.0007023.

8.

Yersinia pestis endowed with increased cytotoxicity is avirulent in a bubonic plague model and induces rapid protection against pneumonic plague.

Zauberman A, Tidhar A, Levy Y, Bar-Haim E, Halperin G, Flashner Y, Cohen S, Shafferman A, Mamroud E.

PLoS One. 2009 Jun 16;4(6):e5938. doi: 10.1371/journal.pone.0005938.

9.

Neutralization of Yersinia pestis-mediated macrophage cytotoxicity by anti-LcrV antibodies and its correlation with protective immunity in a mouse model of bubonic plague.

Zauberman A, Cohen S, Levy Y, Halperin G, Lazar S, Velan B, Shafferman A, Flashner Y, Mamroud E.

Vaccine. 2008 Mar 20;26(13):1616-25. doi: 10.1016/j.vaccine.2008.01.033. Epub 2008 Feb 6.

PMID:
18304706
10.

Enrichment of Yersinia pestis from blood cultures enables rapid antimicrobial susceptibility determination by flow cytometry.

Steinberger-Levy I, Zahavy E, Cohen S, Flashner Y, Mamroud E, Aftalion M, Gur D, Ber R.

Adv Exp Med Biol. 2007;603:339-50.

PMID:
17966430
11.

Disparity between Yersinia pestis and Yersinia enterocolitica O:8 in YopJ/YopP-dependent functions.

Zauberman A, Velan B, Mamroud E, Flashner Y, Shafferman A, Cohen S.

Adv Exp Med Biol. 2007;603:312-20.

PMID:
17966427
12.

Interaction of Yersinia pestis with macrophages: limitations in YopJ-dependent apoptosis.

Zauberman A, Cohen S, Mamroud E, Flashner Y, Tidhar A, Ber R, Elhanany E, Shafferman A, Velan B.

Infect Immun. 2006 Jun;74(6):3239-50.

13.

Generation of Yersinia pestis attenuated strains by signature-tagged mutagenesis in search of novel vaccine candidates.

Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Lazar S, Zvi A, Bino T, Ariel N, Velan B, Shafferman A, Cohen S.

Infect Immun. 2004 Feb;72(2):908-15.

14.

Development of an improved selective agar medium for isolation of Yersinia pestis.

Ber R, Mamroud E, Aftalion M, Tidhar A, Gur D, Flashner Y, Cohen S.

Appl Environ Microbiol. 2003 Oct;69(10):5787-92.

15.

A new selective medium provides improved growth and recoverability of Yersinia pestis.

Ber R, Mamroud E, Aftalion M, Gur D, Tidhar A, Flashner Y, Cohen S.

Adv Exp Med Biol. 2003;529:467-8. No abstract available.

PMID:
12756811
16.

Evaluation of protective immunity induced by Yersinia enterocolitica type-III secretion system mutants.

Mamroud E, Flashner Y, Tidhar A, Ber R, Gur D, Aftalion M, Lazar S, Velan B, Shafferman A, Cohen S.

Adv Exp Med Biol. 2003;529:425-30. No abstract available.

PMID:
12756803
17.

Vaccination with plasmid DNA expressing the Yersinia pestis capsular protein F1 protects mice against plague.

Grosfeld H, Bino T, Flashner Y, Ber R, Mamroud E, Lustig S, Velan B, Shafferman A, Cohen S.

Adv Exp Med Biol. 2003;529:423-4. No abstract available.

PMID:
12756802
18.

Identification of genes involved in Yersinia pestis virulence by signature-tagged mutagenesis.

Flashner Y, Mamroud E, Tidhar A, Ber R, Aftalion M, Gur D, Zvi A, Ariel N, Velan B, Shafferman A, Cohen S.

Adv Exp Med Biol. 2003;529:31-3. No abstract available.

PMID:
12756723
19.

Effective protective immunity to Yersinia pestis infection conferred by DNA vaccine coding for derivatives of the F1 capsular antigen.

Grosfeld H, Cohen S, Bino T, Flashner Y, Ber R, Mamroud E, Kronman C, Shafferman A, Velan B.

Infect Immun. 2003 Jan;71(1):374-83.

20.
21.

Three novel plasmid R6K proteins act in concert to distort DNA within the alpha and beta origins of DNA replication.

Flashner Y, Schlomai J, Shafferman A.

Mol Microbiol. 1996 Mar;19(5):985-96.

PMID:
8830279
22.
23.
24.

Reversal of signal-mediated cellular retention by subunit assembly of human acetylcholinesterase.

Velan B, Kronman C, Flashner Y, Shafferman A.

J Biol Chem. 1994 Sep 9;269(36):22719-25.

25.

N-glycosylation of human acetylcholinesterase: effects on activity, stability and biosynthesis.

Velan B, Kronman C, Ordentlich A, Flashner Y, Leitner M, Cohen S, Shafferman A.

Biochem J. 1993 Dec 15;296 ( Pt 3):649-56.

26.

Dissection of the human acetylcholinesterase active center determinants of substrate specificity. Identification of residues constituting the anionic site, the hydrophobic site, and the acyl pocket.

Ordentlich A, Barak D, Kronman C, Flashner Y, Leitner M, Segall Y, Ariel N, Cohen S, Velan B, Shafferman A.

J Biol Chem. 1993 Aug 15;268(23):17083-95.

27.

Production and secretion of high levels of recombinant human acetylcholinesterase in cultured cell lines: microheterogeneity of the catalytic subunit.

Kronman C, Velan B, Gozes Y, Leitner M, Flashner Y, Lazar A, Marcus D, Sery T, Papier Y, Grosfeld H, et al.

Gene. 1992 Nov 16;121(2):295-304.

PMID:
1446827
28.

Substrate inhibition of acetylcholinesterase: residues affecting signal transduction from the surface to the catalytic center.

Shafferman A, Velan B, Ordentlich A, Kronman C, Grosfeld H, Leitner M, Flashner Y, Cohen S, Barak D, Ariel N.

EMBO J. 1992 Oct;11(10):3561-8.

29.

Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding.

Shafferman A, Kronman C, Flashner Y, Leitner M, Grosfeld H, Ordentlich A, Gozes Y, Cohen S, Ariel N, Barak D, et al.

J Biol Chem. 1992 Sep 5;267(25):17640-8.

30.

The effect of elimination of intersubunit disulfide bonds on the activity, assembly, and secretion of recombinant human acetylcholinesterase. Expression of acetylcholinesterase Cys-580----Ala mutant.

Velan B, Grosfeld H, Kronman C, Leitner M, Gozes Y, Lazar A, Flashner Y, Marcus D, Cohen S, Shafferman A.

J Biol Chem. 1991 Dec 15;266(35):23977-84.

31.

Recombinant human acetylcholinesterase is secreted from transiently transfected 293 cells as a soluble globular enzyme.

Velan B, Kronman C, Grosfeld H, Leitner M, Gozes Y, Flashner Y, Sery T, Cohen S, Ben-Aziz R, Seidman S, et al.

Cell Mol Neurobiol. 1991 Feb;11(1):143-56.

PMID:
1849451
32.

Alpha and beta replication origins of plasmid R6K show similar distortions of the DNA helix in vivo.

Flashner Y, Shafferman A.

Proc Natl Acad Sci U S A. 1990 Dec;87(23):9123-7.

33.

Dual mechanism of repression at a distance in the lac operon.

Flashner Y, Gralla JD.

Proc Natl Acad Sci U S A. 1988 Dec;85(23):8968-72.

34.
35.

Molecular aspects of genetic instability of an artificial 68 bp perfect palindrome in Escherichia coli.

Shafferman A, Flashner Y, Hertman I, Olami Y, Cohen S.

Mol Gen Genet. 1987 Jun;208(1-2):294-300.

PMID:
3302612
36.
37.

DNA repair in the in vivo site specific excision of palindromic sequences.

Shafferman A, Flashner Y, Hertman I, Rein R.

Prog Clin Biol Res. 1985;172A:19-36. No abstract available.

PMID:
2986165
38.

Genetic instability of an artificial palindrom DNA sequence.

Shafferman A, Flashner Y, Hertman I.

J Biomol Struct Dyn. 1983 Dec;1(3):729-42.

PMID:
6400897
39.

New antibiotic substance produced by Salmonella typhimurium LT2.

Ben-Gurion R, Flashner Y.

J Bacteriol. 1982 Oct;152(1):542-4.

40.

ColE1 DNA sequences interacting in cis, essential for mitomycin-C induced lethality.

Shafferman A, Flashner Y, Cohen S.

Mol Gen Genet. 1979 Oct 2;176(1):139-46.

PMID:
396445
41.

A DNA segment within the colicin E1 structural gene on ColE1 affecting immunity to colicin.

Shafferman A, Cohen S, Flashner Y.

Mol Gen Genet. 1978 Sep 8;164(3):259-64.

PMID:
362155

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