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Items: 1 to 50 of 132

1.

Validation of the protein kinase PfCLK3 as a multistage cross-species malarial drug target.

Alam MM, Sanchez-Azqueta A, Janha O, Flannery EL, Mahindra A, Mapesa K, Char AB, Sriranganadane D, Brancucci NMB, Antonova-Koch Y, Crouch K, Simwela NV, Millar SB, Akinwale J, Mitcheson D, Solyakov L, Dudek K, Jones C, Zapatero C, Doerig C, Nwakanma DC, Vázquez MJ, Colmenarejo G, Lafuente-Monasterio MJ, Leon ML, Godoi PHC, Elkins JM, Waters AP, Jamieson AG, Álvaro EF, Ranford-Cartwright LC, Marti M, Winzeler EA, Gamo FJ, Tobin AB.

Science. 2019 Aug 30;365(6456). pii: eaau1682. doi: 10.1126/science.aau1682.

PMID:
31467193
2.

Plasmodium vivax.

Flannery EL, Markus MB, Vaughan AM.

Trends Parasitol. 2019 Jul;35(7):583-584. doi: 10.1016/j.pt.2019.04.005. Epub 2019 Jun 5. No abstract available.

PMID:
31176582
3.

The Plasmodium liver-specific protein 2 (LISP2) is an early marker of liver stage development.

Gupta DK, Dembele L, Voorberg-van der Wel A, Roma G, Yip A, Chuenchob V, Kangwanrangsan N, Ishino T, Vaughan AM, Kappe SH, Flannery EL, Sattabongkot J, Mikolajczak S, Bifani P, Kocken CH, Diagana TT.

Elife. 2019 May 16;8. pii: e43362. doi: 10.7554/eLife.43362.

4.

Transcriptomic analysis reveals reduced transcriptional activity in the malaria parasite Plasmodium cynomolgi during progression into dormancy.

Bertschi NL, Voorberg-van der Wel A, Zeeman AM, Schuierer S, Nigsch F, Carbone W, Knehr J, Gupta DK, Hofman SO, van der Werff N, Nieuwenhuis I, Klooster E, Faber BW, Flannery EL, Mikolajczak SA, Chuenchob V, Shrestha B, Beibel M, Bouwmeester T, Kangwanrangsan N, Sattabongkot J, Diagana TT, Kocken CH, Roma G.

Elife. 2018 Dec 27;7. pii: e41081. doi: 10.7554/eLife.41081.

5.

A recombinant antibody against Plasmodium vivax UIS4 for distinguishing replicating from dormant liver stages.

Schafer C, Dambrauskas N, Steel RW, Carbonetti S, Chuenchob V, Flannery EL, Vigdorovich V, Oliver BG, Roobsoong W, Maher SP, Kyle D, Sattabongkot J, Kappe SHI, Mikolajczak SA, Sather DN.

Malar J. 2018 Oct 17;17(1):370. doi: 10.1186/s12936-018-2519-7.

6.

Lung lobe torsion in dogs: 52 cases (2005-2017).

Park KM, Grimes JA, Wallace ML, Sterman AA, Thieman Mankin KM, Campbell BG, Flannery EE, Milovancev M, Mathews KG, Schmiedt CW.

Vet Surg. 2018 Nov;47(8):1002-1008. doi: 10.1111/vsu.13108. Epub 2018 Oct 10.

PMID:
30303548
7.

Virtual outpatient clinic as an alternative to an actual clinic visit after surgical discharge: a randomised controlled trial.

Healy P, McCrone L, Tully R, Flannery E, Flynn A, Cahir C, Arumugasamy M, Walsh T.

BMJ Qual Saf. 2019 Jan;28(1):24-31. doi: 10.1136/bmjqs-2018-008171. Epub 2018 Oct 5.

PMID:
30291181
8.

Reelin Can Modulate Migration of Olfactory Ensheathing Cells and Gonadotropin Releasing Hormone Neurons via the Canonical Pathway.

Dairaghi L, Flannery E, Giacobini P, Saglam A, Saadi H, Constantin S, Casoni F, Howell BW, Wray S.

Front Cell Neurosci. 2018 Aug 3;12:228. doi: 10.3389/fncel.2018.00228. eCollection 2018.

9.

Characterization of Plasmodium vivax Proteins in Plasma-Derived Exosomes From Malaria-Infected Liver-Chimeric Humanized Mice.

Gualdrón-López M, Flannery EL, Kangwanrangsan N, Chuenchob V, Fernandez-Orth D, Segui-Barber J, Royo F, Falcón-Pérez JM, Fernandez-Becerra C, Lacerda MVG, Kappe SHI, Sattabongkot J, Gonzalez JR, Mikolajczak SA, Del Portillo HA.

Front Microbiol. 2018 Jun 25;9:1271. doi: 10.3389/fmicb.2018.01271. eCollection 2018.

10.

PfCap380 as a marker for Plasmodium falciparum oocyst development in vivo and in vitro.

Itsara LS, Zhou Y, Do J, Dungel S, Fishbaugher ME, Betz WW, Nguyen T, Navarro MJ, Flannery EL, Vaughan AM, Kappe SHI, Ghosh AK.

Malar J. 2018 Apr 2;17(1):135. doi: 10.1186/s12936-018-2277-6.

11.

Plasmodium falciparum Liver Stage Infection and Transition to Stable Blood Stage Infection in Liver-Humanized and Blood-Humanized FRGN KO Mice Enables Testing of Blood Stage Inhibitory Antibodies (Reticulocyte-Binding Protein Homolog 5) In Vivo.

Foquet L, Schafer C, Minkah NK, Alanine DGW, Flannery EL, Steel RWJ, Sack BK, Camargo N, Fishbaugher M, Betz W, Nguyen T, Billman ZP, Wilson EM, Bial J, Murphy SC, Draper SJ, Mikolajczak SA, Kappe SHI.

Front Immunol. 2018 Mar 14;9:524. doi: 10.3389/fimmu.2018.00524. eCollection 2018.

12.

Immunization of Malaria-Preexposed Volunteers With PfSPZ Vaccine Elicits Long-Lived IgM Invasion-Inhibitory and Complement-Fixing Antibodies.

Zenklusen I, Jongo S, Abdulla S, Ramadhani K, Lee Sim BK, Cardamone H, Flannery EL, Nguyen T, Fishbaugher M, Steel RWJ, Betz W, Carmago N, Mikolajczak S, Kappe SHI, Hoffman SL, Sack BK, Daubenberger C.

J Infect Dis. 2018 Apr 23;217(10):1569-1578. doi: 10.1093/infdis/jiy080.

13.

Multimodal Characterization of the Late Effects of Traumatic Brain Injury: A Methodological Overview of the Late Effects of Traumatic Brain Injury Project.

Edlow BL, Keene CD, Perl DP, Iacono D, Folkerth RD, Stewart W, Mac Donald CL, Augustinack J, Diaz-Arrastia R, Estrada C, Flannery E, Gordon WA, Grabowski TJ, Hansen K, Hoffman J, Kroenke C, Larson EB, Lee P, Mareyam A, McNab JA, McPhee J, Moreau AL, Renz A, Richmire K, Stevens A, Tang CY, Tirrell LS, Trittschuh EH, van der Kouwe A, Varjabedian A, Wald LL, Wu O, Yendiki A, Young L, Zöllei L, Fischl B, Crane PK, Dams-O'Connor K.

J Neurotrauma. 2018 Jul 15;35(14):1604-1619. doi: 10.1089/neu.2017.5457. Epub 2018 May 3.

14.

Mapping the malaria parasite druggable genome by using in vitro evolution and chemogenomics.

Cowell AN, Istvan ES, Lukens AK, Gomez-Lorenzo MG, Vanaerschot M, Sakata-Kato T, Flannery EL, Magistrado P, Owen E, Abraham M, LaMonte G, Painter HJ, Williams RM, Franco V, Linares M, Arriaga I, Bopp S, Corey VC, Gnädig NF, Coburn-Flynn O, Reimer C, Gupta P, Murithi JM, Moura PA, Fuchs O, Sasaki E, Kim SW, Teng CH, Wang LT, Akidil A, Adjalley S, Willis PA, Siegel D, Tanaseichuk O, Zhong Y, Zhou Y, Llinás M, Ottilie S, Gamo FJ, Lee MCS, Goldberg DE, Fidock DA, Wirth DF, Winzeler EA.

Science. 2018 Jan 12;359(6372):191-199. doi: 10.1126/science.aan4472.

15.

Assessing drug efficacy against Plasmodium falciparum liver stages in vivo.

Flannery EL, Foquet L, Chuenchob V, Fishbaugher M, Billman Z, Navarro MJ, Betz W, Olsen TM, Lee J, Camargo N, Nguyen T, Schafer C, Sack BK, Wilson EM, Saunders J, Bial J, Campo B, Charman SA, Murphy SC, Phillips MA, Kappe SH, Mikolajczak SA.

JCI Insight. 2018 Jan 11;3(1). pii: 92587. doi: 10.1172/jci.insight.92587. eCollection 2018 Jan 11.

16.

Humoral protection against mosquito bite-transmitted Plasmodium falciparum infection in humanized mice.

Sack BK, Mikolajczak SA, Fishbaugher M, Vaughan AM, Flannery EL, Nguyen T, Betz W, Jane Navarro M, Foquet L, Steel RWJ, Billman ZP, Murphy SC, Hoffman SL, Chakravarty S, Sim BKL, Behet M, Reuling IJ, Walk J, Scholzen A, Sauerwein RW, Ishizuka AS, Flynn B, Seder RA, Kappe SHI.

NPJ Vaccines. 2017 Oct 9;2:27. doi: 10.1038/s41541-017-0028-2. eCollection 2017.

17.

A Global Survey of ATPase Activity in Plasmodium falciparum Asexual Blood Stages and Gametocytes.

Ortega C, Frando A, Webb-Robertson BJ, Anderson LN, Fleck N, Flannery EL, Fishbaugher M, Murphree TA, Hansen JR, Smith RD, Kappe SHI, Wright AT, Grundner C.

Mol Cell Proteomics. 2018 Jan;17(1):111-120. doi: 10.1074/mcp.RA117.000088. Epub 2017 Oct 27.

18.

Proteogenomic analysis of the total and surface-exposed proteomes of Plasmodium vivax salivary gland sporozoites.

Swearingen KE, Lindner SE, Flannery EL, Vaughan AM, Morrison RD, Patrapuvich R, Koepfli C, Muller I, Jex A, Moritz RL, Kappe SHI, Sattabongkot J, Mikolajczak SA.

PLoS Negl Trop Dis. 2017 Jul 31;11(7):e0005791. doi: 10.1371/journal.pntd.0005791. eCollection 2017 Jul.

19.

Antimalarial drug discovery - approaches and progress towards new medicines.

Flannery EL, Chatterjee AK, Winzeler EA.

Nat Rev Microbiol. 2017 Sep;15(9):572. doi: 10.1038/nrmicro.2017.88. Epub 2017 Jul 24. No abstract available.

PMID:
28736448
20.

Effects of ovarian fluid and genetic differences on sperm performance and fertilization success of alternative reproductive tactics in Chinook salmon.

Lehnert SJ, Butts IAE, Flannery EW, Peters KM, Heath DD, Pitcher TE.

J Evol Biol. 2017 Jun;30(6):1236-1245. doi: 10.1111/jeb.13088. Epub 2017 May 2.

21.

An Opsonic Phagocytosis Assay for Plasmodium falciparum Sporozoites.

Steel RW, Sack BK, Tsuji M, Navarro MJ, Betz W, Fishbaugher ME, Flannery EL, Kappe SH.

Clin Vaccine Immunol. 2017 Feb 6;24(2). pii: e00445-16. doi: 10.1128/CVI.00445-16. Print 2017 Feb.

22.

An Increase in Healthcare-Associated Clostridium difficile Infection Associated with Use of a Defective Peracetic Acid-Based Surface Disinfectant.

Cadnum JL, Jencson AL, O'Donnell MC, Flannery ER, Nerandzic MM, Donskey CJ.

Infect Control Hosp Epidemiol. 2017 Mar;38(3):300-305. doi: 10.1017/ice.2016.275. Epub 2016 Nov 21.

PMID:
27866475
23.

High-Throughput Assay and Discovery of Small Molecules that Interrupt Malaria Transmission.

Plouffe DM, Wree M, Du AY, Meister S, Li F, Patra K, Lubar A, Okitsu SL, Flannery EL, Kato N, Tanaseichuk O, Comer E, Zhou B, Kuhen K, Zhou Y, Leroy D, Schreiber SL, Scherer CA, Vinetz J, Winzeler EA.

Cell Host Microbe. 2016 Jan 13;19(1):114-26. doi: 10.1016/j.chom.2015.12.001. Epub 2015 Dec 31.

24.

Next-Generation Sequencing of Plasmodium vivax Patient Samples Shows Evidence of Direct Evolution in Drug-Resistance Genes.

Flannery EL, Wang T, Akbari A, Corey VC, Gunawan F, Bright AT, Abraham M, Sanchez JF, Santolalla ML, Baldeviano GC, Edgel KA, Rosales LA, Lescano AG, Bafna V, Vinetz JM, Winzeler EA.

ACS Infect Dis. 2015 Aug 14;1(8):367-79. doi: 10.1021/acsinfecdis.5b00049. Epub 2015 Aug 3.

25.

Perception vs Reality: Methicillin-Resistant Staphylococcus aureus Carriage Among Healthcare Workers at a Veterans Affairs Medical Center.

Colburn NE, Cadnum J, Flannery E, Chang S, Donskey CJ, Stiefel U.

Infect Control Hosp Epidemiol. 2016 Jan;37(1):110-2. doi: 10.1017/ice.2015.242. Epub 2015 Nov 3.

PMID:
26526505
26.

Chitosan/interfering RNA nanoparticle mediated gene silencing in disease vector mosquito larvae.

Zhang X, Mysore K, Flannery E, Michel K, Severson DW, Zhu KY, Duman-Scheel M.

J Vis Exp. 2015 Mar 25;(97). doi: 10.3791/52523.

27.

Mutations in the P-type cation-transporter ATPase 4, PfATP4, mediate resistance to both aminopyrazole and spiroindolone antimalarials.

Flannery EL, McNamara CW, Kim SW, Kato TS, Li F, Teng CH, Gagaring K, Manary MJ, Barboa R, Meister S, Kuhen K, Vinetz JM, Chatterjee AK, Winzeler EA.

ACS Chem Biol. 2015 Feb 20;10(2):413-20. doi: 10.1021/cb500616x. Epub 2014 Nov 5.

28.

Role of semaphorin-1a in the developing visual system of the disease vector mosquito Aedes aegypti.

Mysore K, Flannery E, Leming MT, Tomchaney M, Shi L, Sun L, O'Tousa JE, Severson DW, Duman-Scheel M.

Dev Dyn. 2014 Nov;243(11):1457-69. doi: 10.1002/dvdy.24168. Epub 2014 Jul 31.

29.

KAF156 is an antimalarial clinical candidate with potential for use in prophylaxis, treatment, and prevention of disease transmission.

Kuhen KL, Chatterjee AK, Rottmann M, Gagaring K, Borboa R, Buenviaje J, Chen Z, Francek C, Wu T, Nagle A, Barnes SW, Plouffe D, Lee MC, Fidock DA, Graumans W, van de Vegte-Bolmer M, van Gemert GJ, Wirjanata G, Sebayang B, Marfurt J, Russell B, Suwanarusk R, Price RN, Nosten F, Tungtaeng A, Gettayacamin M, Sattabongkot J, Taylor J, Walker JR, Tully D, Patra KP, Flannery EL, Vinetz JM, Renia L, Sauerwein RW, Winzeler EA, Glynne RJ, Diagana TT.

Antimicrob Agents Chemother. 2014 Sep;58(9):5060-7. doi: 10.1128/AAC.02727-13. Epub 2014 Jun 9.

30.

Identification of pathogen genomic variants through an integrated pipeline.

Manary MJ, Singhakul SS, Flannery EL, Bopp SE, Corey VC, Bright AT, McNamara CW, Walker JR, Winzeler EA.

BMC Bioinformatics. 2014 Mar 3;15:63. doi: 10.1186/1471-2105-15-63.

31.

The indirect role of fibroblast growth factor-8 in defining neurogenic niches of the olfactory/GnRH systems.

Forni PE, Bharti K, Flannery EM, Shimogori T, Wray S.

J Neurosci. 2013 Dec 11;33(50):19620-34. doi: 10.1523/JNEUROSCI.3238-13.2013.

32.

Antimalarial drug discovery - approaches and progress towards new medicines.

Flannery EL, Chatterjee AK, Winzeler EA.

Nat Rev Microbiol. 2013 Dec;11(12):849-62. doi: 10.1038/nrmicro3138. Epub 2013 Nov 11. Review. Erratum in: Nat Rev Microbiol. 2014 Jan;12(1):70. Nat Rev Microbiol. 2017 Sep;15(9):572.

33.

Using genetic methods to define the targets of compounds with antimalarial activity.

Flannery EL, Fidock DA, Winzeler EA.

J Med Chem. 2013 Oct 24;56(20):7761-71. doi: 10.1021/jm400325j. Epub 2013 Sep 6. Review.

34.

Disruption of Aedes aegypti olfactory system development through chitosan/siRNA nanoparticle targeting of semaphorin-1a.

Mysore K, Flannery EM, Tomchaney M, Severson DW, Duman-Scheel M.

PLoS Negl Trop Dis. 2013 May 16;7(5):e2215. doi: 10.1371/journal.pntd.0002215. Print 2013.

35.

Infection rate and colonization with antibiotic-resistant organisms in skilled nursing facility residents with indwelling devices.

Wang L, Lansing B, Symons K, Flannery EL, Fisch J, Cherian K, McNamara SE, Mody L.

Eur J Clin Microbiol Infect Dis. 2012 Aug;31(8):1797-804. doi: 10.1007/s10096-011-1504-7. Epub 2012 Jan 25.

36.
37.

Comparative genomic analysis of Drosophila melanogaster and vector mosquito developmental genes.

Behura SK, Haugen M, Flannery E, Sarro J, Tessier CR, Severson DW, Duman-Scheel M.

PLoS One. 2011;6(7):e21504. doi: 10.1371/journal.pone.0021504. Epub 2011 Jul 6.

38.

Semaphorin-1a is required for Aedes aegypti embryonic nerve cord development.

Haugen M, Flannery E, Tomchaney M, Mori A, Behura SK, Severson DW, Duman-Scheel M.

PLoS One. 2011;6(6):e21694. doi: 10.1371/journal.pone.0021694. Epub 2011 Jun 27.

39.

The Drosophila Netrin receptor frazzled/DCC functions as an invasive tumor suppressor.

VanZomeren-Dohm A, Sarro J, Flannery E, Duman-Scheel M.

BMC Dev Biol. 2011 Jun 14;11:41. doi: 10.1186/1471-213X-11-41.

40.
41.

Patterns of ciprofloxacin-resistant gram-negative bacteria colonization in nursing home residents.

Dommeti P, Wang L, Flannery EL, Symons K, Mody L.

Infect Control Hosp Epidemiol. 2011 Feb;32(2):177-80. doi: 10.1086/657946.

42.

The aesthetic impact of enamel fluorosis on Irish adolescents.

Browne D, Whelton H, O'Mullane D, Tavener J, Flannery E.

Community Dent Oral Epidemiol. 2011 Apr;39(2):127-36. doi: 10.1111/j.1600-0528.2010.00577.x. Epub 2011 Jan 3.

PMID:
21198759
43.

Immunohistochemical analysis of protein expression during Aedes aegypti development.

Clemons A, Flannery E, Kast K, Severson D, Duman-Scheel M.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.prot5510. doi: 10.1101/pdb.prot5510.

44.

Whole-mount in situ hybridization for analysis of gene expression during Aedes aegypti development.

Haugen M, Tomchaney M, Kast K, Flannery E, Clemons A, Jacowski C, Simanton Holland W, Le C, Severson D, Duman-Scheel M.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.prot5509. doi: 10.1101/pdb.prot5509.

45.

Fixation and preparation of developing tissues from Aedes aegypti.

Clemons A, Haugen M, Flannery E, Kast K, Jacowski C, Severson D, Duman-Scheel M.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.prot5508. doi: 10.1101/pdb.prot5508.

46.

Aedes aegypti: an emerging model for vector mosquito development.

Clemons A, Haugen M, Flannery E, Tomchaney M, Kast K, Jacowski C, Le C, Mori A, Simanton Holland W, Sarro J, Severson DW, Duman-Scheel M.

Cold Spring Harb Protoc. 2010 Oct 1;2010(10):pdb.emo141. doi: 10.1101/pdb.emo141.

47.

"The hard hunger": famine, sexuality, and form in Eugene McCabe's Tales from the poorhouse.

Flannery E.

New Hibernia Rev. 2010;14(2):49-68. No abstract available.

PMID:
20684084
48.

Composition, variability, and temporal stability of the intestinal microbiota of the elderly.

Claesson MJ, Cusack S, O'Sullivan O, Greene-Diniz R, de Weerd H, Flannery E, Marchesi JR, Falush D, Dinan T, Fitzgerald G, Stanton C, van Sinderen D, O'Connor M, Harnedy N, O'Connor K, Henry C, O'Mahony D, Fitzgerald AP, Shanahan F, Twomey C, Hill C, Ross RP, O'Toole PW.

Proc Natl Acad Sci U S A. 2011 Mar 15;108 Suppl 1:4586-91. doi: 10.1073/pnas.1000097107. Epub 2010 Jun 22.

49.

Induction of cellular growth by the axon guidance regulators netrin A and semaphorin-1a.

Flannery E, VanZomeren-Dohm A, Beach P, Holland WS, Duman-Scheel M.

Dev Neurobiol. 2010 Jun;70(7):473-84. doi: 10.1002/dneu.20788.

50.

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