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Items: 7

1.

Inhibition of the stromal p38MAPK/MK2 pathway limits breast cancer metastases and chemotherapy-induced bone loss.

Murali B, Ren Q, Luo X, Faget DV, Wang C, Johnson RM, Gruosso T, Flanagan KC, Fu Y, Leahy KM, Alspach E, Su X, Ross MH, Burnette B, Weilbaecher KN, Park M, Mbalaviele G, Monahan J, Stewart SA.

Cancer Res. 2018 Aug 9. pii: canres.0234.2018. doi: 10.1158/0008-5472.CAN-18-0234. [Epub ahead of print]

PMID:
30093561
2.

c-Myb and C/EBPβ regulate OPN and other senescence-associated secretory phenotype factors.

Flanagan KC, Alspach E, Pazolli E, Parajuli S, Ren Q, Arthur LL, Tapia R, Stewart SA.

Oncotarget. 2017 Dec 5;9(1):21-36. doi: 10.18632/oncotarget.22940. eCollection 2018 Jan 2.

3.

p38 MAPK inhibits nonsense-mediated RNA decay in response to persistent DNA damage in noncycling cells.

Nickless A, Cheruiyot A, Flanagan KC, Piwnica-Worms D, Stewart SA, You Z.

J Biol Chem. 2017 Sep 15;292(37):15266-15276. doi: 10.1074/jbc.M117.787846. Epub 2017 Aug 1.

PMID:
28765281
4.

Stromal senescence establishes an immunosuppressive microenvironment that drives tumorigenesis.

Ruhland MK, Loza AJ, Capietto AH, Luo X, Knolhoff BL, Flanagan KC, Belt BA, Alspach E, Leahy K, Luo J, Schaffer A, Edwards JR, Longmore G, Faccio R, DeNardo DG, Stewart SA.

Nat Commun. 2016 Jun 8;7:11762. doi: 10.1038/ncomms11762.

5.

p38MAPK plays a crucial role in stromal-mediated tumorigenesis.

Alspach E, Flanagan KC, Luo X, Ruhland MK, Huang H, Pazolli E, Donlin MJ, Marsh T, Piwnica-Worms D, Monahan J, Novack DV, McAllister SS, Stewart SA.

Cancer Discov. 2014 Jun;4(6):716-29. doi: 10.1158/2159-8290.CD-13-0743. Epub 2014 Mar 26.

6.

The CRTC1-SIK1 pathway regulates entrainment of the circadian clock.

Jagannath A, Butler R, Godinho SIH, Couch Y, Brown LA, Vasudevan SR, Flanagan KC, Anthony D, Churchill GC, Wood MJA, Steiner G, Ebeling M, Hossbach M, Wettstein JG, Duffield GE, Gatti S, Hankins MW, Foster RG, Peirson SN.

Cell. 2013 Aug 29;154(5):1100-1111. doi: 10.1016/j.cell.2013.08.004.

7.

Tissue factor contributes to neutrophil CD11b expression in alpha-naphthylisothiocyanate-treated mice.

Luyendyk JP, Flanagan KC, Williams CD, Jaeschke H, Slusser JG, Mackman N, Cantor GH.

Toxicol Appl Pharmacol. 2011 Feb 1;250(3):256-62. doi: 10.1016/j.taap.2010.11.002. Epub 2010 Nov 9.

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