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Items: 1 to 50 of 189

1.

Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons.

Koppers M, Cagnetta R, Shigeoka T, Wunderlich LC, Vallejo-Ramirez P, Qiaojin Lin J, Zhao S, Jakobs MA, Dwivedy A, Minett MS, Bellon A, Kaminski CF, Harris WA, Flanagan JG, Holt CE.

Elife. 2019 Nov 20;8. pii: e48718. doi: 10.7554/eLife.48718.

2.

Insulin Receptor Associates with Promoters Genome-wide and Regulates Gene Expression.

Hancock ML, Meyer RC, Mistry M, Khetani RS, Wagschal A, Shin T, Ho Sui SJ, Näär AM, Flanagan JG.

Cell. 2019 Apr 18;177(3):722-736.e22. doi: 10.1016/j.cell.2019.02.030. Epub 2019 Apr 4.

PMID:
30955890
3.

Retinal blood oxygen saturation and aqueous humour biomarkers in early diabetic retinopathy.

Tayyari F, Khuu LA, Sivak JM, Flanagan JG, Singer S, Brent MH, Hudson C.

Acta Ophthalmol. 2019 Aug;97(5):e673-e679. doi: 10.1111/aos.14016. Epub 2019 Jan 28.

PMID:
30690929
4.

All roads lead to glaucoma: Induced retinal injury cascades contribute to a common neurodegenerative outcome.

Alqawlaq S, Flanagan JG, Sivak JM.

Exp Eye Res. 2019 Jun;183:88-97. doi: 10.1016/j.exer.2018.11.005. Epub 2018 Nov 14. Review.

PMID:
30447198
5.

Validation of the UNC OCT Index for the Diagnosis of Early Glaucoma.

Mwanza JC, Lee G, Budenz DL, Warren JL, Wall M, Artes PH, Callan TM, Flanagan JG.

Transl Vis Sci Technol. 2018 Apr 3;7(2):16. doi: 10.1167/tvst.7.2.16. eCollection 2018 Apr.

6.

Structural Characterization of a Heparan Sulfate Pentamer Interacting with LAR-Ig1-2.

Gao Q, Yang JY, Moremen KW, Flanagan JG, Prestegard JH.

Biochemistry. 2018 Apr 17;57(15):2189-2199. doi: 10.1021/acs.biochem.8b00241. Epub 2018 Apr 3.

7.

Comparison of laser and circumlimbal suture induced elevation of intraocular pressure in albino CD-1 mice.

Liu HH, Zhang L, Shi M, Chen L, Flanagan JG.

PLoS One. 2017 Nov 30;12(11):e0189094. doi: 10.1371/journal.pone.0189094. eCollection 2017.

8.

Astrocyte-derived lipoxins A4 and B4 promote neuroprotection from acute and chronic injury.

Livne-Bar I, Wei J, Liu HH, Alqawlaq S, Won GJ, Tuccitto A, Gronert K, Flanagan JG, Sivak JM.

J Clin Invest. 2017 Dec 1;127(12):4403-4414. doi: 10.1172/JCI77398. Epub 2017 Nov 6.

9.

Lamina Cribrosa Pore Shape and Size as Predictors of Neural Tissue Mechanical Insult.

Voorhees AP, Jan NJ, Austin ME, Flanagan JG, Sivak JM, Bilonick RA, Sigal IA.

Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5336-5346. doi: 10.1167/iovs.17-22015.

10.

Establishment and Characterization of an Acute Model of Ocular Hypertension by Laser-Induced Occlusion of Episcleral Veins.

Zhang L, Li G, Shi M, Liu HH, Ge S, Ou Y, Flanagan JG, Chen L.

Invest Ophthalmol Vis Sci. 2017 Aug 1;58(10):3879-3886. doi: 10.1167/iovs.16-20807.

11.

Aqueous humor endothelin-1 and total retinal blood flow in patients with non-proliferative diabetic retinopathy.

Khuu LA, Tayyari F, Sivak JM, Flanagan JG, Singer S, Brent MH, Huang D, Tan O, Hudson C.

Eye (Lond). 2017 Oct;31(10):1443-1450. doi: 10.1038/eye.2017.74. Epub 2017 May 26.

12.

Twenty-four hour intraocular pressure monitoring with the SENSIMED Triggerfish contact lens: effect of body posture during sleep.

Beltran-Agulló L, Buys YM, Jahan F, Shapiro CM, Flanagan JG, Cheng J, Trope GE.

Br J Ophthalmol. 2017 Oct;101(10):1323-1328. doi: 10.1136/bjophthalmol-2016-308710. Epub 2017 Mar 7.

PMID:
28270491
13.

A Mouse Model of Chronic Ocular Hypertension Induced by Circumlimbal Suture.

Liu HH, Flanagan JG.

Invest Ophthalmol Vis Sci. 2017 Jan 1;58(1):353-361. doi: 10.1167/iovs.16-20576.

PMID:
28118662
14.

Pharmacologic inhibition of reactive gliosis blocks TNF-α-mediated neuronal apoptosis.

Livne-Bar I, Lam S, Chan D, Guo X, Askar I, Nahirnyj A, Flanagan JG, Sivak JM.

Cell Death Dis. 2016 Sep 29;7(9):e2386. doi: 10.1038/cddis.2016.277.

15.

Aqueous humour concentrations of TGF-β, PLGF and FGF-1 and total retinal blood flow in patients with early non-proliferative diabetic retinopathy.

Khuu LA, Tayyari F, Sivak JM, Flanagan JG, Singer S, Brent MH, Huang D, Tan O, Hudson C.

Acta Ophthalmol. 2017 May;95(3):e206-e211. doi: 10.1111/aos.13230. Epub 2016 Sep 28.

16.

Retinal Oxygen Saturation in Patients with Primary Open-angle Glaucoma Using a Non-flash Hypespectral Camera.

Shahidi AM, Hudson C, Tayyari F, Flanagan JG.

Curr Eye Res. 2017 Apr;42(4):557-561. doi: 10.1080/02713683.2016.1217544. Epub 2016 Sep 9.

PMID:
27612016
17.

IMP2 axonal localization, RNA interactome, and function in the development of axon trajectories.

Preitner N, Quan J, Li X, Nielsen FC, Flanagan JG.

Development. 2016 Aug 1;143(15):2753-9. doi: 10.1242/dev.128348. Epub 2016 Jul 6.

18.

Biomechanical insult switches PEA-15 activity to uncouple its anti-apoptotic function and promote erk mediated tissue remodeling.

Exler RE, Guo X, Chan D, Livne-Bar I, Vicic N, Flanagan JG, Sivak JM.

Exp Cell Res. 2016 Jan 15;340(2):283-94. doi: 10.1016/j.yexcr.2015.11.023. Epub 2015 Nov 23.

PMID:
26615958
19.

Relationship between retinal blood flow and arterial oxygen.

Cheng RW, Yusof F, Tsui E, Jong M, Duffin J, Flanagan JG, Fisher JA, Hudson C.

J Physiol. 2016 Feb 1;594(3):625-40. doi: 10.1113/JP271182. Epub 2015 Dec 30.

20.

Retinal Blood Flow and Retinal Blood Oxygen Saturation in Mild to Moderate Diabetic Retinopathy.

Tayyari F, Khuu LA, Flanagan JG, Singer S, Brent MH, Hudson C.

Invest Ophthalmol Vis Sci. 2015 Oct;56(11):6796-800. doi: 10.1167/iovs.15-17481.

PMID:
26567792
21.

Variability and repeatability of quantitative, Fourier-domain optical coherence tomography Doppler blood flow in young and elderly healthy subjects.

Tayyari F, Yusof F, Vymyslicky M, Tan O, Huang D, Flanagan JG, Hudson C.

Invest Ophthalmol Vis Sci. 2014 Oct 21;55(12):7716-25. doi: 10.1167/iovs.14-14430.

PMID:
25335983
22.

Normative Databases for Imaging Instrumentation.

Realini T, Zangwill LM, Flanagan JG, Garway-Heath D, Patella VM, Johnson CA, Artes PH, Gaddie IB, Fingeret M.

J Glaucoma. 2015 Aug;24(6):480-3. doi: 10.1097/IJG.0000000000000152.

23.

The effect of hypercapnia on the sensitivity to flicker defined stimuli.

Shahidi AM, Hudson C, Patel SR, Flanagan JG.

Br J Ophthalmol. 2015 Mar;99(3):323-8. doi: 10.1136/bjophthalmol-2013-304814. Epub 2014 Sep 17.

PMID:
25232025
24.

Application of Elliptic Fourier analysis to describe the lamina cribrosa shape with age and intraocular pressure.

Sanfilippo PG, Grimm JL, Flanagan JG, Lathrop KL, Sigal IA.

Exp Eye Res. 2014 Nov;128:1-7. doi: 10.1016/j.exer.2014.08.013. Epub 2014 Sep 2.

25.

Grader learning effect and reproducibility of Doppler Spectral-Domain Optical Coherence Tomography derived retinal blood flow measurements.

Rose K, Jong M, Yusof F, Tayyari F, Tan O, Huang D, Sadda SR, Flanagan JG, Hudson C.

Acta Ophthalmol. 2014 Dec;92(8):e630-6. doi: 10.1111/aos.12479. Epub 2014 Jul 6.

26.

Assessment of total retinal blood flow using Doppler Fourier Domain Optical Coherence Tomography during systemic hypercapnia and hypocapnia.

Shahidi AM, Patel SR, Huang D, Tan O, Flanagan JG, Hudson C.

Physiol Rep. 2014 Jul 18;2(7). pii: e12046. doi: 10.14814/phy2.12046. Print 2014 Jul 1.

27.

APC is an RNA-binding protein, and its interactome provides a link to neural development and microtubule assembly.

Preitner N, Quan J, Nowakowski DW, Hancock ML, Shi J, Tcherkezian J, Young-Pearse TL, Flanagan JG.

Cell. 2014 Jul 17;158(2):368-382. doi: 10.1016/j.cell.2014.05.042.

28.

Preclinical development and ocular biodistribution of gemini-DNA nanoparticles after intravitreal and topical administration: towards non-invasive glaucoma gene therapy.

Alqawlaq S, Sivak JM, Huzil JT, Ivanova MV, Flanagan JG, Beazely MA, Foldvari M.

Nanomedicine. 2014 Nov;10(8):1637-47. doi: 10.1016/j.nano.2014.05.010. Epub 2014 Jun 4.

PMID:
24905400
29.

Retinal blood flow and vascular reactivity in chronic smokers.

Rose K, Flanagan JG, Patel SR, Cheng R, Hudson C.

Invest Ophthalmol Vis Sci. 2014 May 6;55(7):4266-76. doi: 10.1167/iovs.14-14022.

PMID:
24801513
30.

Clinical significance of optic disc progression by topographic change analysis maps in glaucoma: an 8-year follow-up study.

Kourkoutas D, Buys YM, Flanagan JG, Karamaounas N, Georgopoulos G, Iliakis E, Moschos MM, Trope GE.

J Ophthalmol. 2014;2014:987389. doi: 10.1155/2014/987389. Epub 2014 Jan 21.

31.

PGC-1α signaling coordinates susceptibility to metabolic and oxidative injury in the inner retina.

Guo X, Dason ES, Zanon-Moreno V, Jiang Q, Nahirnyj A, Chan D, Flanagan JG, Sivak JM.

Am J Pathol. 2014 Apr;184(4):1017-1029. doi: 10.1016/j.ajpath.2013.12.012. Epub 2014 Feb 5.

PMID:
24508229
32.

Optical origins of opposing facial expression actions.

Lee DH, Mirza R, Flanagan JG, Anderson AK.

Psychol Sci. 2014 Mar;25(3):745-52. doi: 10.1177/0956797613514451. Epub 2014 Jan 24.

PMID:
24463554
33.

MicroRNA-132 is enriched in developing axons, locally regulates Rasa1 mRNA, and promotes axon extension.

Hancock ML, Preitner N, Quan J, Flanagan JG.

J Neurosci. 2014 Jan 1;34(1):66-78. doi: 10.1523/JNEUROSCI.3371-13.2014.

34.

The effect of simulated cataract light scatter on retinal vessel oximetry.

Patel SR, Hudson C, Flanagan JG, Heitmar R.

Exp Eye Res. 2013 Nov;116:185-9. doi: 10.1016/j.exer.2013.09.004. Epub 2013 Sep 19.

PMID:
24056207
35.

A prototype hyperspectral system with a tunable laser source for retinal vessel imaging.

Patel SR, Flanagan JG, Shahidi AM, Sylvestre JP, Hudson C.

Invest Ophthalmol Vis Sci. 2013 Aug 1;54(8):5163-8. doi: 10.1167/iovs.13-12124.

PMID:
23821191
36.

Regional variation in human retinal vessel oxygen saturation.

Shahidi AM, Patel SR, Flanagan JG, Hudson C.

Exp Eye Res. 2013 Aug;113:143-7. doi: 10.1016/j.exer.2013.06.001. Epub 2013 Jun 18.

PMID:
23791637
37.

This message will self-destruct: NMD regulates axon guidance.

Preitner N, Quan J, Flanagan JG.

Cell. 2013 Jun 6;153(6):1185-7. doi: 10.1016/j.cell.2013.05.019.

38.

Human lamina cribrosa insertion and age.

Sigal IA, Flanagan JG, Lathrop KL, Tertinegg I, Bilonick R.

Invest Ophthalmol Vis Sci. 2012 Oct 3;53(11):6870-9. doi: 10.1167/iovs.12-9890.

39.

Proteomics analyses of activated human optic nerve head lamina cribrosa cells following biomechanical strain.

Rogers R, Dharsee M, Ackloo S, Flanagan JG.

Invest Ophthalmol Vis Sci. 2012 Jun 20;53(7):3806-16. doi: 10.1167/iovs.11-8480.

PMID:
22589438
40.

Axonal mRNA translation: an unexpected link to axon survival and the mitochondrion.

Preitner N, Flanagan JG.

Neuron. 2012 Feb 23;73(4):629-31. doi: 10.1016/j.neuron.2012.02.005.

41.

Generic versus brand-name North American topical glaucoma drops.

Mammo ZN, Flanagan JG, James DF, Trope GE.

Can J Ophthalmol. 2012 Feb;47(1):55-61. doi: 10.1016/j.jcjo.2011.12.004.

PMID:
22333853
42.

Proteomics analyses of human optic nerve head astrocytes following biomechanical strain.

Rogers RS, Dharsee M, Ackloo S, Sivak JM, Flanagan JG.

Mol Cell Proteomics. 2012 Feb;11(2):M111.012302. doi: 10.1074/mcp.M111.012302. Epub 2011 Nov 29.

43.

Type III neuregulin 1 regulates pathfinding of sensory axons in the developing spinal cord and periphery.

Hancock ML, Nowakowski DW, Role LW, Talmage DA, Flanagan JG.

Development. 2011 Nov;138(22):4887-98. doi: 10.1242/dev.072306.

44.

High-resolution optical coherence tomography retinal imaging: a case series illustrating potential and limitations.

Puzyeyeva O, Lam WC, Flanagan JG, Brent MH, Devenyi RG, Mandelcorn MS, Wong T, Hudson C.

J Ophthalmol. 2011;2011:764183. doi: 10.1155/2011/764183. Epub 2011 Sep 29.

45.

The Toronto epidemiology glaucoma survey: a pilot study.

Anraku A, Jin YP, Butty Z, Jinapriya D, Alasbali T, Mammo Z, Flanagan JG, Trope GE.

Can J Ophthalmol. 2011 Aug;46(4):352-7. doi: 10.1016/j.jcjo.2011.06.013. Epub 2011 Jul 7.

PMID:
21816256
46.

Proteoglycan-specific molecular switch for RPTPσ clustering and neuronal extension.

Coles CH, Shen Y, Tenney AP, Siebold C, Sutton GC, Lu W, Gallagher JT, Jones EY, Flanagan JG, Aricescu AR.

Science. 2011 Apr 22;332(6028):484-8. doi: 10.1126/science.1200840. Epub 2011 Mar 31.

47.

Vascular reactivity of optic nerve head and retinal blood vessels in glaucoma--a review.

Venkataraman ST, Flanagan JG, Hudson C.

Microcirculation. 2010 Oct;17(7):568-81. doi: 10.1111/j.1549-8719.2010.00045.x. Review.

PMID:
21040122
48.

Finite element modeling of the human sclera: influence on optic nerve head biomechanics and connections with glaucoma.

Norman RE, Flanagan JG, Sigal IA, Rausch SM, Tertinegg I, Ethier CR.

Exp Eye Res. 2011 Jul;93(1):4-12. doi: 10.1016/j.exer.2010.09.014. Epub 2010 Sep 29.

PMID:
20883693
49.

Sterile single use cover for the G-probe Transscleral Cyclodiode.

Rootman DB, Howarth D, Kerr JQ, Flanagan JG, Trope GE, Buys YM.

J Glaucoma. 2011 Apr-May;20(4):260-5. doi: 10.1097/IJG.0b013e3181e08109.

PMID:
20577100
50.

The association between diurnal variation of optic nerve head topography and intraocular pressure and ocular perfusion pressure in untreated primary open-angle glaucoma.

Sehi M, Flanagan JG, Zeng L, Cook RJ, Trope GE.

J Glaucoma. 2011 Jan;20(1):44-50. doi: 10.1097/IJG.0b013e3181d2603b.

PMID:
20436368

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