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Items: 1 to 50 of 56

1.

Physical and functional interplay between PCNA DNA clamp and Mre11-Rad50 complex from the archaeon Pyrococcus furiosus.

Hogrel G, Lu Y, Laurent S, Henry E, Etienne C, Phung DK, Dulermo R, Bossé A, Pluchon PF, Clouet-d'Orval B, Flament D.

Nucleic Acids Res. 2018 Jun 20;46(11):5651-5663. doi: 10.1093/nar/gky322.

2.

Development of an Effective 6-Methylpurine Counterselection Marker for Genetic Manipulation in Thermococcus barophilus.

Birien T, Thiel A, Henneke G, Flament D, Moalic Y, Jebbar M.

Genes (Basel). 2018 Feb 7;9(2). pii: E77. doi: 10.3390/genes9020077.

3.

Modelization of the regulation of protein synthesis following fertilization in sea urchin shows requirement of two processes: a destabilization of eIF4E:4E-BP complex and a great stimulation of the 4E-BP-degradation mechanism, both rapamycin-sensitive.

Laurent S, Richard A, Mulner-Lorillon O, Morales J, Flament D, Glippa V, Bourdon J, Gosselin P, Siegel A, Cormier P, Bellé R.

Front Genet. 2014 May 6;5:117. doi: 10.3389/fgene.2014.00117. eCollection 2014.

4.

Genetic manipulations of the hyperthermophilic piezophilic archaeon Thermococcus barophilus.

Thiel A, Michoud G, Moalic Y, Flament D, Jebbar M.

Appl Environ Microbiol. 2014 Apr;80(7):2299-306. doi: 10.1128/AEM.00084-14. Epub 2014 Jan 31.

5.

An extended network of genomic maintenance in the archaeon Pyrococcus abyssi highlights unexpected associations between eucaryotic homologs.

Pluchon PF, Fouqueau T, Crezé C, Laurent S, Briffotaux J, Hogrel G, Palud A, Henneke G, Godfroy A, Hausner W, Thomm M, Nicolas J, Flament D.

PLoS One. 2013 Nov 7;8(11):e79707. doi: 10.1371/journal.pone.0079707. eCollection 2013.

6.

Crystal structure of PAV1-137: a protein from the virus PAV1 that infects Pyrococcus abyssi.

Leulliot N, Quevillon-Cheruel S, Graille M, Geslin C, Flament D, Le Romancer M, van Tilbeurgh H.

Archaea. 2013;2013:568053. doi: 10.1155/2013/568053. Epub 2013 Mar 4.

7.

Modulation of the Pyrococcus abyssi NucS endonuclease activity by replication clamp at functional and structural levels.

Creze C, Ligabue A, Laurent S, Lestini R, Laptenok SP, Khun J, Vos MH, Czjzek M, Myllykallio H, Flament D.

J Biol Chem. 2012 May 4;287(19):15648-60. doi: 10.1074/jbc.M112.346361. Epub 2012 Mar 19.

8.

Structure and function of a novel endonuclease acting on branched DNA substrates.

Creze C, Lestini R, Kühn J, Ligabue A, Becker HF, Czjzek M, Flament D, Myllykallio H.

Biochem Soc Trans. 2011 Jan;39(1):145-9. doi: 10.1042/BST0390145.

PMID:
21265762
9.

MARINE-EXPRESS: taking advantage of high throughput cloning and expression strategies for the post-genomic analysis of marine organisms.

Groisillier A, Hervé C, Jeudy A, Rebuffet E, Pluchon PF, Chevolot Y, Flament D, Geslin C, Morgado IM, Power D, Branno M, Moreau H, Michel G, Boyen C, Czjzek M.

Microb Cell Fact. 2010 Jun 14;9:45. doi: 10.1186/1475-2859-9-45.

10.

The glycine-rich motif of Pyrococcus abyssi DNA polymerase D is critical for protein stability.

Castrec B, Laurent S, Henneke G, Flament D, Raffin JP.

J Mol Biol. 2010 Mar 5;396(4):840-8. doi: 10.1016/j.jmb.2010.01.006. Epub 2010 Jan 11.

PMID:
20070946
11.

Binding to PCNA in Euryarchaeal DNA Replication requires two PIP motifs for DNA polymerase D and one PIP motif for DNA polymerase B.

Castrec B, Rouillon C, Henneke G, Flament D, Querellou J, Raffin JP.

J Mol Biol. 2009 Nov 27;394(2):209-18. doi: 10.1016/j.jmb.2009.09.044. Epub 2009 Sep 23.

PMID:
19781553
12.

Structure and function of a novel endonuclease acting on branched DNA substrates.

Ren B, Kühn J, Meslet-Cladiere L, Briffotaux J, Norais C, Lavigne R, Flament D, Ladenstein R, Myllykallio H.

EMBO J. 2009 Aug 19;28(16):2479-89. doi: 10.1038/emboj.2009.192. Epub 2009 Jul 16.

13.

Impaired compensation for mechanical loads in a patient with hemiballismus following stroke.

Flament D, Shannon KM, Neyman I, Nicholas JJ, Corcos DM.

Parkinsonism Relat Disord. 2000 Jan;6(1):49-56.

PMID:
18591149
14.

The heterodimeric primase from the euryarchaeon Pyrococcus abyssi: a multifunctional enzyme for initiation and repair?

Le Breton M, Henneke G, Norais C, Flament D, Myllykallio H, Querellou J, Raffin JP.

J Mol Biol. 2007 Dec 14;374(5):1172-85. Epub 2007 Oct 12.

PMID:
17991487
15.

A novel proteomic approach identifies new interaction partners for proliferating cell nuclear antigen.

Meslet-Cladiére L, Norais C, Kuhn J, Briffotaux J, Sloostra JW, Ferrari E, Hübscher U, Flament D, Myllykallio H.

J Mol Biol. 2007 Oct 5;372(5):1137-48. Epub 2007 Jun 27.

PMID:
17720188
16.

Alpha-agarases define a new family of glycoside hydrolases, distinct from beta-agarase families.

Flament D, Barbeyron T, Jam M, Potin P, Czjzek M, Kloareg B, Michel G.

Appl Environ Microbiol. 2007 Jul;73(14):4691-4. Epub 2007 May 18.

17.

Structural insights into a new homodimeric self-activated GTPase family.

Gras S, Chaumont V, Fernandez B, Carpentier P, Charrier-Savournin F, Schmitt S, Pineau C, Flament D, Hecker A, Forterre P, Armengaud J, Housset D.

EMBO Rep. 2007 Jun;8(6):569-75. Epub 2007 Apr 20.

18.

Analysis of the first genome of a hyperthermophilic marine virus-like particle, PAV1, isolated from Pyrococcus abyssi.

Geslin C, Gaillard M, Flament D, Rouault K, Le Romancer M, Prieur D, Erauso G.

J Bacteriol. 2007 Jun;189(12):4510-9. Epub 2007 Apr 20.

19.

DNA polymerase switching on homotrimeric PCNA at the replication fork of the euryarchaea Pyrococcus abyssi.

Rouillon C, Henneke G, Flament D, Querellou J, Raffin JP.

J Mol Biol. 2007 Jun 1;369(2):343-55. Epub 2007 Mar 24.

PMID:
17442344
20.

The hyperthermophilic euryarchaeota Pyrococcus abyssi likely requires the two DNA polymerases D and B for DNA replication.

Henneke G, Flament D, Hübscher U, Querellou J, Raffin JP.

J Mol Biol. 2005 Jul 1;350(1):53-64.

PMID:
15922358
21.

The endo-beta-agarases AgaA and AgaB from the marine bacterium Zobellia galactanivorans: two paralogue enzymes with different molecular organizations and catalytic behaviours.

Jam M, Flament D, Allouch J, Potin P, Thion L, Kloareg B, Czjzek M, Helbert W, Michel G, Barbeyron T.

Biochem J. 2005 Feb 1;385(Pt 3):703-13.

22.

Genetic elements of Thermococcales.

Prieur D, Erauso G, Geslin C, Lucas S, Gaillard M, Bidault A, Mattenet AC, Rouault K, Flament D, Forterre P, Le Romancer M.

Biochem Soc Trans. 2004 Apr;32(Pt 2):184-7. Review.

PMID:
15046568
23.

EMG remains fractionated in Parkinson's disease, despite practice-related improvements in performance.

Flament D, Vaillancourt DE, Kempf T, Shannon K, Corcos DM.

Clin Neurophysiol. 2003 Dec;114(12):2385-96.

PMID:
14652099
24.

An integrated analysis of the genome of the hyperthermophilic archaeon Pyrococcus abyssi.

Cohen GN, Barbe V, Flament D, Galperin M, Heilig R, Lecompte O, Poch O, Prieur D, Quérellou J, Ripp R, Thierry JC, Van der Oost J, Weissenbach J, Zivanovic Y, Forterre P.

Mol Microbiol. 2003 Mar;47(6):1495-512.

25.

Immune gene discovery by expressed sequence tags generated from hemocytes of the bacteria-challenged oyster, Crassostrea gigas.

Gueguen Y, Cadoret JP, Flament D, Barreau-Roumiguière C, Girardot AL, Garnier J, Hoareau A, Bachère E, Escoubas JM.

Gene. 2003 Jan 16;303:139-45.

PMID:
12559575
26.

Replication factor C from the hyperthermophilic archaeon Pyrococcus abyssi does not need ATP hydrolysis for clamp-loading and contains a functionally conserved RFC PCNA-binding domain.

Henneke G, Gueguen Y, Flament D, Azam P, Querellou J, Dietrich J, Hübscher U, Raffin JP.

J Mol Biol. 2002 Nov 8;323(5):795-810.

PMID:
12417194
27.
28.

Reaction time is not impaired by stimulation of the ventral-intermediate nucleus of the thalamus (Vim) in patients with tremor.

Flament D, Shapiro MB, Pfann KD, Moore CG, Penn RD, Corcos DM.

Mov Disord. 2002 May;17(3):488-92.

PMID:
12112195
29.

Characterization of two DNA polymerases from the hyperthermophilic euryarchaeon Pyrococcus abyssi.

Gueguen Y, Rolland JL, Lecompte O, Azam P, Le Romancer G, Flament D, Raffin JP, Dietrich J.

Eur J Biochem. 2001 Nov;268(22):5961-9.

30.

Characterization of a highly thermostable alkaline phosphatase from the euryarchaeon Pyrococcus abyssi.

Zappa S, Rolland JL, Flament D, Gueguen Y, Boudrant J, Dietrich J.

Appl Environ Microbiol. 2001 Oct;67(10):4504-11.

31.
32.

Characterization of the maltooligosyl trehalose synthase from the thermophilic archaeon Sulfolobus acidocaldarius.

Gueguen Y, Rolland JL, Schroeck S, Flament D, Defretin S, Saniez MH, Dietrich J.

FEMS Microbiol Lett. 2001 Jan 15;194(2):201-6.

33.

Representation of accuracy in the dorsal premotor cortex.

Gomez JE, Fu Q, Flament D, Ebner TJ.

Eur J Neurosci. 2000 Oct;12(10):3748-60.

PMID:
11029645
34.

Expression, purification, crystallization and preliminary X-ray analysis of the iota-carrageenase from Alteromonas fortis.

Michel G, Flament D, Barbeyron T, Vernet T, Kloareg B, Dideberg O.

Acta Crystallogr D Biol Crystallogr. 2000 Jun;56(Pt 6):766-8.

PMID:
10818359
35.

Time course and temporal order of changes in movement kinematics during learning of fast and accurate elbow flexions.

Flament D, Shapiro MB, Kempf T, Corcos DM.

Exp Brain Res. 1999 Dec;129(3):441-50.

PMID:
10591915
36.

Expression, purification, crystallization and preliminary x-ray analysis of the kappa-carrageenase from Pseudoalteromonas carrageenovora.

Michel G, Barbeyron T, Flament D, Vernet T, Kloareg B, Dideberg O.

Acta Crystallogr D Biol Crystallogr. 1999 Apr;55(Pt 4):918-20.

PMID:
10089334
37.
38.

Relationship of cerebellar Purkinje cell simple spike discharge to movement kinematics in the monkey.

Fu QG, Flament D, Coltz JD, Ebner TJ.

J Neurophysiol. 1997 Jul;78(1):478-91.

39.

Movement kinematics encoded in complex spike discharge of primate cerebellar Purkinje cells.

Fu QG, Mason CR, Flament D, Coltz JD, Ebner TJ.

Neuroreport. 1997 Jan 20;8(2):523-9.

PMID:
9080441
40.

Response patterns and postspike effects of premotor neurons in cervical spinal cord of behaving monkeys.

Fetz EE, Perlmutter SI, Maier MA, Flament D, Fortier PA.

Can J Physiol Pharmacol. 1996 Apr;74(4):531-46.

PMID:
8828898
41.

Functional magnetic resonance imaging of cerebellar activation during the learning of a visuomotor dissociation task.

Flament D, Ellermann JM, Kim SG, Ugurbil K, Ebner TJ.

Hum Brain Mapp. 1996;4(3):210-26. doi: 10.1002/hbm.460040302.

PMID:
20408199
42.

Temporal encoding of movement kinematics in the discharge of primate primary motor and premotor neurons.

Fu QG, Flament D, Coltz JD, Ebner TJ.

J Neurophysiol. 1995 Feb;73(2):836-54.

PMID:
7760138
43.

Spatial patterns of functional activation of the cerebellum investigated using high field (4 T) MRI.

Ellerman JM, Flament D, Kim SG, Fu QG, Merkle H, Ebner TJ, Uğurbil K.

NMR Biomed. 1994 Mar;7(1-2):63-8.

PMID:
8068527
44.

Task dependence of responses in first dorsal interosseous muscle to magnetic brain stimulation in man.

Flament D, Goldsmith P, Buckley CJ, Lemon RN.

J Physiol. 1993 May;464:361-78.

45.

Distance- and error-related discharge of cells in premotor cortex of rhesus monkeys.

Flament D, Onstott D, Fu QG, Ebner TJ.

Neurosci Lett. 1993 Apr 30;153(2):144-8.

PMID:
8327188
46.

Response patterns and postspike effects of peripheral afferents in dorsal root ganglia of behaving monkeys.

Flament D, Fortier PA, Fetz EE.

J Neurophysiol. 1992 Apr;67(4):875-89.

PMID:
1588388
49.

Non-invasive brain stimulation reveals reorganized cortical outputs in amputees.

Hall EJ, Flament D, Fraser C, Lemon RN.

Neurosci Lett. 1990 Aug 24;116(3):379-86.

PMID:
2243618
50.

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