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Items: 16


BST-236, a novel cytarabine prodrug for patients with acute leukemia unfit for standard induction: a phase 1/2a study.

Zuckerman T, Ram R, Akria L, Koren-Michowitz M, Hoffman R, Henig I, Lavi N, Ofran Y, Horowitz NA, Nudelman O, Tavor S, Yeganeh S, Gengrinovitch S, Flaishon L, Tessler S, Ben Yakar R, Rowe JM.

Blood Adv. 2019 Nov 26;3(22):3740-3749. doi: 10.1182/bloodadvances.2019000468.


Efficacy outcomes in the treatment of older or medically unfit patients with acute myeloid leukaemia: A systematic review and meta-analysis.

Stone A, Zukerman T, Flaishon L, Yakar RB, Rowe JM.

Leuk Res. 2019 Jul;82:36-42. doi: 10.1016/j.leukres.2019.05.007. Epub 2019 May 21.


Human placenta-derived stromal cells decrease inflammation, placental injury and blood pressure in hypertensive pregnant mice.

Chatterjee P, Chiasson VL, Pinzur L, Raveh S, Abraham E, Jones KA, Bounds KR, Ofir R, Flaishon L, Chajut A, Mitchell BM.

Clin Sci (Lond). 2016 Apr 1;130(7):513-23. doi: 10.1042/CS20150555. Epub 2015 Dec 18.


Anti-inflammatory effects of an inflammatory chemokine: CCL2 inhibits lymphocyte homing by modulation of CCL21-triggered integrin-mediated adhesions.

Flaishon L, Hart G, Zelman E, Moussion C, Grabovsky V, Lapidot Tal G, Feigelson S, Margalit R, Harmelin A, Avin-Wittenberg T, Shoseyov D, Alon R, Girard JP, Shachar I.

Blood. 2008 Dec 15;112(13):5016-25. doi: 10.1182/blood-2007-12-129122. Epub 2008 Sep 18.


CD74 induces TAp63 expression leading to B-cell survival.

Lantner F, Starlets D, Gore Y, Flaishon L, Yamit-Hezi A, Dikstein R, Leng L, Bucala R, Machluf Y, Oren M, Shachar I.

Blood. 2007 Dec 15;110(13):4303-11. Epub 2007 Sep 10.


IL-12 and IL-18 down-regulate B cell migration in an Ly49D-dependent manner.

Hart G, Flaishon L, Shachar I.

Eur J Immunol. 2007 Jul;37(7):1996-2007.


IFN-gamma acts on T cells to induce NK cell mobilization and accumulation in target organs.

Wald O, Weiss ID, Wald H, Shoham H, Bar-Shavit Y, Beider K, Galun E, Weiss L, Flaishon L, Shachar I, Nagler A, Lu B, Gerard C, Gao JL, Mishani E, Farber J, Peled A.

J Immunol. 2006 Apr 15;176(8):4716-29.


Grb7 expression and cellular migration in chronic lymphocytic leukemia: a comparative study of early and advanced stage disease.

Haran M, Chebatco S, Flaishon L, Lantner F, Harpaz N, Valinsky L, Berrebi A, Shachar I.

Leukemia. 2004 Dec;18(12):1948-50.


Expression of the chemokine receptor CCR2 on immature B cells negatively regulates their cytoskeletal rearrangement and migration.

Flaishon L, Becker-Herman S, Hart G, Levo Y, Kuziel WA, Shachar I.

Blood. 2004 Aug 15;104(4):933-41. Epub 2004 May 4.


Ly49D receptor expressed on immature B cells regulates their IFN-gamma secretion, actin polymerization, and homing.

Hart G, Flaishon L, Becker-Herman S, Shachar I.

J Immunol. 2003 Nov 1;171(9):4630-8.


Cutting edge: anti-inflammatory properties of low levels of IFN-gamma.

Flaishon L, Topilski I, Shoseyov D, Hershkoviz R, Fireman E, Levo Y, Marmor S, Shachar I.

J Immunol. 2002 Apr 15;168(8):3707-11.


Invariant chain induces B cell maturation in a process that is independent of its chaperonic activity.

Matza D, Lantner F, Bogoch Y, Flaishon L, Hershkoviz R, Shachar I.

Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):3018-23. Epub 2002 Feb 26.


Low levels of IFN-gamma down-regulate the integrin-dependent adhesion of B cells by activating a pathway that interferes with cytoskeleton rearrangement.

Flaishon L, Lantner F, Hershkoviz R, Levo Y, Shachar I.

J Biol Chem. 2001 Dec 14;276(50):46701-6. Epub 2001 Oct 3.


Autocrine secretion of interferon gamma negatively regulates homing of immature B cells.

Flaishon L, Hershkoviz R, Lantner F, Lider O, Alon R, Levo Y, Flavell RA, Shachar I.

J Exp Med. 2000 Nov 6;192(9):1381-8.

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