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Best matches for Flügel A[au]:

Vascular, glial, and lymphatic immune gateways of the central nervous system. Engelhardt B et al. Acta Neuropathol. (2016)

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid. Schläger C et al. Nature. (2016)

Intravital real-time analysis of T-cell activation in health and disease. Lodygin D et al. Cell Calcium. (2017)

Search results

Items: 1 to 50 of 75

1.

Publisher Correction: β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration.

Lodygin D, Hermann M, Schweingruber N, Flügel-Koch C, Watanabe T, Schlosser C, Merlini A, Körner H, Chang HF, Fischer HJ, Reichardt HM, Zagrebelsky M, Mollenhauer B, Kügler S, Fitzner D, Frahm J, Stadelmann C, Haberl M, Odoardi F, Flügel A.

Nature. 2019 Mar;567(7749):E15. doi: 10.1038/s41586-019-1047-0.

PMID:
30867589
2.

β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration.

Lodygin D, Hermann M, Schweingruber N, Flügel-Koch C, Watanabe T, Schlosser C, Merlini A, Körner H, Chang HF, Fischer HJ, Reichardt HM, Zagrebelsky M, Mollenhauer B, Kügler S, Fitzner D, Frahm J, Stadelmann C, Haberl M, Odoardi F, Flügel A.

Nature. 2019 Feb;566(7745):503-508. doi: 10.1038/s41586-019-0964-2. Epub 2019 Feb 20. Erratum in: Nature. 2019 Mar;567(7749):E15.

PMID:
30787438
3.

ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.

Diercks BP, Werner R, Weidemüller P, Czarniak F, Hernandez L, Lehmann C, Rosche A, Krüger A, Kaufmann U, Vaeth M, Failla AV, Zobiak B, Kandil FI, Schetelig D, Ruthenbeck A, Meier C, Lodygin D, Flügel A, Ren D, Wolf IMA, Feske S, Guse AH.

Sci Signal. 2018 Dec 18;11(561). pii: eaat0358. doi: 10.1126/scisignal.aat0358.

PMID:
30563862
4.

Small Molecule Antagonists of NAADP-Induced Ca2+ Release in T-Lymphocytes Suggest Potential Therapeutic Agents for Autoimmune Disease.

Zhang B, Watt JM, Cordiglieri C, Dammermann W, Mahon MF, Flügel A, Guse AH, Potter BVL.

Sci Rep. 2018 Nov 13;8(1):16775. doi: 10.1038/s41598-018-34917-3.

5.

Trapped in the epineurium: early entry into the endoneurium is restricted to neuritogenic T cells in experimental autoimmune neuritis.

Mausberg AK, Szepanowski F, Odoardi F, Flügel A, Kleinschnitz C, Stettner M, Kieseier BC.

J Neuroinflammation. 2018 Aug 1;15(1):217. doi: 10.1186/s12974-018-1259-5.

6.

Astrocytic expression of the CXCL12 receptor, CXCR7/ACKR3 is a hallmark of the diseased, but not developing CNS.

Puchert M, Pelkner F, Stein G, Angelov DN, Boltze J, Wagner DC, Odoardi F, Flügel A, Streit WJ, Engele J.

Mol Cell Neurosci. 2017 Dec;85:105-118. doi: 10.1016/j.mcn.2017.09.001. Epub 2017 Sep 8.

PMID:
28889992
7.

Laquinimod enhances central nervous system barrier functions.

Lühder F, Kebir H, Odoardi F, Litke T, Sonneck M, Alvarez JI, Winchenbach J, Eckert N, Hayardeny L, Sorani E, Lodygin D, Flügel A, Prat A.

Neurobiol Dis. 2017 Jun;102:60-69. doi: 10.1016/j.nbd.2017.02.002. Epub 2017 Feb 22.

PMID:
28235673
8.

Intravital real-time analysis of T-cell activation in health and disease.

Lodygin D, Flügel A.

Cell Calcium. 2017 Jun;64:118-129. doi: 10.1016/j.ceca.2016.12.007. Epub 2016 Dec 28. Review.

PMID:
28126314
9.

Vascular, glial, and lymphatic immune gateways of the central nervous system.

Engelhardt B, Carare RO, Bechmann I, Flügel A, Laman JD, Weller RO.

Acta Neuropathol. 2016 Sep;132(3):317-38. doi: 10.1007/s00401-016-1606-5. Epub 2016 Aug 13. Review.

10.

Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease.

Flach AC, Litke T, Strauss J, Haberl M, Gómez CC, Reindl M, Saiz A, Fehling HJ, Wienands J, Odoardi F, Lühder F, Flügel A.

Proc Natl Acad Sci U S A. 2016 Mar 22;113(12):3323-8. doi: 10.1073/pnas.1519608113. Epub 2016 Mar 8.

11.

Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid.

Schläger C, Körner H, Krueger M, Vidoli S, Haberl M, Mielke D, Brylla E, Issekutz T, Cabañas C, Nelson PJ, Ziemssen T, Rohde V, Bechmann I, Lodygin D, Odoardi F, Flügel A.

Nature. 2016 Feb 18;530(7590):349-53. doi: 10.1038/nature16939. Epub 2016 Feb 10.

PMID:
26863192
12.

Modulation of CNS autoimmune responses by CD8(+) T cells coincides with their oligoclonal expansion.

Fischer HJ, van den Brandt J, Lingner T, Odoardi F, Flügel A, Weishaupt A, Reichardt HM.

J Neuroimmunol. 2016 Jan 15;290:26-32. doi: 10.1016/j.jneuroim.2015.10.020. Epub 2015 Oct 29.

PMID:
26711565
13.

Frontrunners of T cell activation: Initial, localized Ca2+ signals mediated by NAADP and the type 1 ryanodine receptor.

Wolf IM, Diercks BP, Gattkowski E, Czarniak F, Kempski J, Werner R, Schetelig D, Mittrücker HW, Schumacher V, von Osten M, Lodygin D, Flügel A, Fliegert R, Guse AH.

Sci Signal. 2015 Oct 13;8(398):ra102. doi: 10.1126/scisignal.aab0863.

PMID:
26462735
14.

Calcium Signalling Triggered by NAADP in T Cells Determines Cell Shape and Motility During Immune Synapse Formation.

Nebel M, Zhang B, Odoardi F, Flügel A, Potter BV, Guse AH.

Messenger (Los Angel). 2015 Jun;4(1):104-111.

15.

Thymocyte-derived BDNF influences T-cell maturation at the DN3/DN4 transition stage.

Linker RA, Lee DH, Flach AC, Litke T, van den Brandt J, Reichardt HM, Lingner T, Bommhardt U, Sendtner M, Gold R, Flügel A, Lühder F.

Eur J Immunol. 2015 May;45(5):1326-38. doi: 10.1002/eji.201444985. Epub 2015 Feb 19.

16.

In Vivo Visualization of (Auto)Immune Processes in the Central Nervous System of Rodents.

Schläger C, Litke T, Flügel A, Odoardi F.

Methods Mol Biol. 2016;1304:117-29. doi: 10.1007/7651_2014_150.

PMID:
25549830
17.

Pain-induced skin autoimmunity.

Odoardi F, Neuhuber W, Flügel A.

Cell Res. 2014 Sep;24(9):1021-2. doi: 10.1038/cr.2014.80. Epub 2014 Jun 20.

18.

Chemokine-mediated redirection of T cells constitutes a critical mechanism of glucocorticoid therapy in autoimmune CNS responses.

Schweingruber N, Fischer HJ, Fischer L, van den Brandt J, Karabinskaya A, Labi V, Villunger A, Kretzschmar B, Huppke P, Simons M, Tuckermann JP, Flügel A, Lühder F, Reichardt HM.

Acta Neuropathol. 2014 May;127(5):713-29. doi: 10.1007/s00401-014-1248-4. Epub 2014 Feb 1.

19.

[ How do we release T cells from an autoimmune disease of the central nervous system?].

Flügel A.

Drug Res (Stuttg). 2013 Nov;63 Suppl 1:S6. doi: 10.1055/s-0033-1346706. Epub 2013 Nov 15. German. No abstract available.

20.

Broadband two-color laser-induced incandescence pyrometry approach for nanoparticle characterization with improved sensitivity.

Flügel A, Kiefer J, Will S, Leipertz A.

Appl Spectrosc. 2013 Sep;67(9):1098-100. doi: 10.1366/13-06998.

PMID:
24067642
21.

The potential for genetically altered microglia to influence glioma treatment.

Li W, Holsinger RM, Kruse CA, Flügel A, Graeber MB.

CNS Neurol Disord Drug Targets. 2013 Sep;12(6):750-62. Review.

22.

A combination of fluorescent NFAT and H2B sensors uncovers dynamics of T cell activation in real time during CNS autoimmunity.

Lodygin D, Odoardi F, Schläger C, Körner H, Kitz A, Nosov M, van den Brandt J, Reichardt HM, Haberl M, Flügel A.

Nat Med. 2013 Jun;19(6):784-90. doi: 10.1038/nm.3182. Epub 2013 Apr 28.

PMID:
23624600
23.

Brain-derived neurotrophic factor in neuroimmunology: lessons learned from multiple sclerosis patients and experimental autoimmune encephalomyelitis models.

Lühder F, Gold R, Flügel A, Linker RA.

Arch Immunol Ther Exp (Warsz). 2013 Apr;61(2):95-105. doi: 10.1007/s00005-012-0211-0. Epub 2013 Jan 3. Review.

PMID:
23283517
24.

T cells become licensed in the lung to enter the central nervous system.

Odoardi F, Sie C, Streyl K, Ulaganathan VK, Schläger C, Lodygin D, Heckelsmiller K, Nietfeld W, Ellwart J, Klinkert WE, Lottaz C, Nosov M, Brinkmann V, Spang R, Lehrach H, Vingron M, Wekerle H, Flügel-Koch C, Flügel A.

Nature. 2012 Aug 30;488(7413):675-9. doi: 10.1038/nature11337.

PMID:
22914092
25.

Courage, luck and patience: in celebration of the 80th birthday of Georg W. Kreutzberg.

Graeber MB, Banati RB, Flügel A, Streit WJ, Tetzlaff W.

Acta Neuropathol. 2012 Oct;124(4):593-8. doi: 10.1007/s00401-012-1033-1. Epub 2012 Aug 12. No abstract available.

PMID:
22886135
26.

Autoimmunity's next top models.

Wekerle H, Flügel A, Fugger L, Schett G, Serreze D.

Nat Med. 2012 Jan 6;18(1):66-70. doi: 10.1038/nm.2635. No abstract available.

PMID:
22227675
27.

Autoimmune disease in the brain--how to spot the culprits and how to keep them in check.

Flügel A, Schläger C, Lühder F, Odoardi F.

J Neurol Sci. 2011 Dec;311 Suppl 1:S3-11.

PMID:
22206764
28.

Central nervous system rather than immune cell-derived BDNF mediates axonal protective effects early in autoimmune demyelination.

Lee DH, Geyer E, Flach AC, Jung K, Gold R, Flügel A, Linker RA, Lühder F.

Acta Neuropathol. 2012 Feb;123(2):247-58. doi: 10.1007/s00401-011-0890-3. Epub 2011 Oct 19.

29.

CXCL12 expression within the CNS contributes to the resistance against experimental autoimmune encephalomyelitis in Albino Oxford rats.

Miljković D, Stanojević Z, Momcilović M, Odoardi F, Flügel A, Mostarica-Stojković M.

Immunobiology. 2011 Sep;216(9):979-87. doi: 10.1016/j.imbio.2011.03.013. Epub 2011 Apr 7.

PMID:
21601937
30.

Knocking at the brain's door: intravital two-photon imaging of autoreactive T cell interactions with CNS structures.

Kawakami N, Flügel A.

Semin Immunopathol. 2010 Sep;32(3):275-87. doi: 10.1007/s00281-010-0216-x. Epub 2010 Jul 11. Review.

31.

T cell vaccination induces the elimination of EAE effector T cells: analysis using GFP-transduced, encephalitogenic T cells.

Volovitz I, Marmor Y, Mor F, Flügel A, Odoardi F, Eisenbach L, Cohen IR.

J Autoimmun. 2010 Sep;35(2):135-44. doi: 10.1016/j.jaut.2010.05.003. Epub 2010 Jun 26.

PMID:
20580204
32.

Nicotinic acid adenine dinucleotide phosphate-mediated calcium signalling in effector T cells regulates autoimmunity of the central nervous system.

Cordiglieri C, Odoardi F, Zhang B, Nebel M, Kawakami N, Klinkert WE, Lodygin D, Lühder F, Breunig E, Schild D, Ulaganathan VK, Dornmair K, Dammermann W, Potter BV, Guse AH, Flügel A.

Brain. 2010 Jul;133(Pt 7):1930-43. doi: 10.1093/brain/awq135. Epub 2010 Jun 2.

33.

Effector T cell interactions with meningeal vascular structures in nascent autoimmune CNS lesions.

Bartholomäus I, Kawakami N, Odoardi F, Schläger C, Miljkovic D, Ellwart JW, Klinkert WE, Flügel-Koch C, Issekutz TB, Wekerle H, Flügel A.

Nature. 2009 Nov 5;462(7269):94-8. doi: 10.1038/nature08478. Epub 2009 Oct 14.

PMID:
19829296
34.

NAADP-mediated Ca2+ signaling via type 1 ryanodine receptor in T cells revealed by a synthetic NAADP antagonist.

Dammermann W, Zhang B, Nebel M, Cordiglieri C, Odoardi F, Kirchberger T, Kawakami N, Dowden J, Schmid F, Dornmair K, Hohenegger M, Flügel A, Guse AH, Potter BV.

Proc Natl Acad Sci U S A. 2009 Jun 30;106(26):10678-83. doi: 10.1073/pnas.0809997106. Epub 2009 Jun 16.

35.

8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist.

Kirchberger T, Moreau C, Wagner GK, Fliegert R, Siebrands CC, Nebel M, Schmid F, Harneit A, Odoardi F, Flügel A, Potter BV, Guse AH.

Biochem J. 2009 Jul 29;422(1):139-49. doi: 10.1042/BJ20082308.

36.

Laser sheet dropsizing based on two-dimensional Raman and Mie scattering.

Malarski A, Schürer B, Schmitz I, Zigan L, Flügel A, Leipertz A.

Appl Opt. 2009 Apr 1;48(10):1853-60.

PMID:
19340138
37.

Neurotrophic factor-expressing mesenchymal stem cells survive transplantation into the contused spinal cord without differentiating into neural cells.

Rooney GE, McMahon SS, Ritter T, Garcia Y, Moran C, Madigan NN, Flügel A, Dockery P, O'Brien T, Howard L, Windebank AJ, Barry FP.

Tissue Eng Part A. 2009 Oct;15(10):3049-59. doi: 10.1089/ten.TEA.2009.0045.

PMID:
19335061
38.

Imaging of effector memory T cells during a delayed-type hypersensitivity reaction and suppression by Kv1.3 channel block.

Matheu MP, Beeton C, Garcia A, Chi V, Rangaraju S, Safrina O, Monaghan K, Uemura MI, Li D, Pal S, de la Maza LM, Monuki E, Flügel A, Pennington MW, Parker I, Chandy KG, Cahalan MD.

Immunity. 2008 Oct 17;29(4):602-14. doi: 10.1016/j.immuni.2008.07.015. Epub 2008 Oct 2.

39.

Gene-modified mesenchymal stem cells express functionally active nerve growth factor on an engineered poly lactic glycolic acid (PLGA) substrate.

Rooney GE, Moran C, McMahon SS, Ritter T, Maenz M, Flügel A, Dockery P, O'Brien T, Howard L, Windebank AJ, Barry FP.

Tissue Eng Part A. 2008 May;14(5):681-90. doi: 10.1089/tea.2007.0260.

PMID:
18402551
40.

A CD28 superagonistic antibody elicits 2 functionally distinct waves of T cell activation in rats.

Müller N, van den Brandt J, Odoardi F, Tischner D, Herath J, Flügel A, Reichardt HM.

J Clin Invest. 2008 Apr;118(4):1405-16. doi: 10.1172/JCI32698.

41.

Blood-borne soluble protein antigen intensifies T cell activation in autoimmune CNS lesions and exacerbates clinical disease.

Odoardi F, Kawakami N, Klinkert WE, Wekerle H, Flügel A.

Proc Natl Acad Sci U S A. 2007 Nov 20;104(47):18625-30. Epub 2007 Nov 13.

42.

Autoaggressive effector T cells in the course of experimental autoimmune encephalomyelitis visualized in the light of two-photon microscopy.

Flügel A, Odoardi F, Nosov M, Kawakami N.

J Neuroimmunol. 2007 Nov;191(1-2):86-97. Epub 2007 Oct 31. Review.

PMID:
17976745
43.

Transition from enhanced T cell infiltration to inflammation in the myelin-degenerative central nervous system.

Grundtner R, Dornmair K, Dahm R, Flügel A, Kawakami N, Zeitelhofer M, Schoderboeck L, Nosov M, Selzer E, Willheim M, Kiebler M, Wekerle H, Lassmann H, Bradl M.

Neurobiol Dis. 2007 Dec;28(3):261-75. Epub 2007 Aug 3.

PMID:
17889548
44.

Local overexpression of nerve growth factor in rat corneal transplants improves allograft survival.

Gong N, Pleyer U, Vogt K, Anegon I, Flügel A, Volk HD, Ritter T.

Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1043-52.

PMID:
17325145
45.

Instant effect of soluble antigen on effector T cells in peripheral immune organs during immunotherapy of autoimmune encephalomyelitis.

Odoardi F, Kawakami N, Li Z, Cordiglieri C, Streyl K, Nosov M, Klinkert WE, Ellwart JW, Bauer J, Lassmann H, Wekerle H, Flügel A.

Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):920-5. Epub 2007 Jan 9.

46.

[The balloon dissector in expander treatment: A ten-year experience in plastic and reconstructive surgery].

Oestreich K, Flügel A, Raab N, Germann G, Jester A.

Handchir Mikrochir Plast Chir. 2006 Aug;38(4):240-5. German.

PMID:
16991044
47.

[Ulnar nerve lesions after osteosynthesis of a supercondylar humerus fracture during childhood. Indications for revision].

Jester A, Flügel A, Germann G, Oestreich K.

Unfallchirurg. 2006 Dec;109(12):1090-3. German.

PMID:
16969654
48.

Cellular effects and metabolic stability of N1-cyclic inosine diphosphoribose and its derivatives.

Kirchberger T, Wagner G, Xu J, Cordiglieri C, Wang P, Gasser A, Fliegert R, Bruhn S, Flügel A, Lund FE, Zhang LH, Potter BV, Guse AH.

Br J Pharmacol. 2006 Oct;149(4):337-44. Epub 2006 Sep 11.

49.

[Defect coverage of the hand with the free serratus fascial flap].

Flügel A, Heitmann C, Kehrer A, Germann G, Sauerbier M.

Handchir Mikrochir Plast Chir. 2005 Jun;37(3):186-92. German.

PMID:
15997430
50.

Autoimmune CD4+ T cell memory: lifelong persistence of encephalitogenic T cell clones in healthy immune repertoires.

Kawakami N, Odoardi F, Ziemssen T, Bradl M, Ritter T, Neuhaus O, Lassmann H, Wekerle H, Flügel A.

J Immunol. 2005 Jul 1;175(1):69-81.

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