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Items: 1 to 50 of 105

1.

Phagocytosis of a PFOB-Nanoemulsion for 19F Magnetic Resonance Imaging: First Results in Monocytes of Patients with Stable Coronary Artery Disease and ST-Elevation Myocardial Infarction.

Nienhaus F, Colley D, Jahn A, Pfeiler S, Flocke V, Temme S, Kelm M, Gerdes N, Flögel U, Bönner F.

Molecules. 2019 May 30;24(11). pii: E2058. doi: 10.3390/molecules24112058.

2.

A2bR-dependent signaling alters immune cell composition and enhances IL-6 formation in the ischemic heart.

Alter C, Ding Z, Flögel U, Scheller J, Schrader J.

Am J Physiol Heart Circ Physiol. 2019 May 3. doi: 10.1152/ajpheart.00029.2019. [Epub ahead of print]

PMID:
31050560
3.

Cardiac Hyaluronan Synthesis Is Critically Involved in the Cardiac Macrophage Response and Promotes Healing After Ischemia Reperfusion Injury.

Petz A, Grandoch M, Gorski DJ, Abrams M, Piroth M, Schneckmann R, Homann S, Müller J, Hartwig S, Lehr S, Yamaguchi Y, Wight TN, Gorressen S, Ding Z, Kötter S, Krüger M, Heinen A, Kelm M, Gödecke A, Flögel U, Fischer JW.

Circ Res. 2019 May 10;124(10):1433-1447. doi: 10.1161/CIRCRESAHA.118.313285.

PMID:
30916618
4.

Special issue on fluorine-19 magnetic resonance: technical solutions, research promises and frontier applications.

Waiczies S, Srinivas M, Flögel U, Boehm-Sturm P, Niendorf T.

MAGMA. 2019 Feb;32(1):1-3. doi: 10.1007/s10334-019-00741-7. No abstract available.

PMID:
30730025
5.

Simultaneous Assessment of Cardiac Inflammation and Extracellular Matrix Remodeling after Myocardial Infarction.

Ramos IT, Henningsson M, Nezafat M, Lavin B, Lorrio S, Gebhardt P, Protti A, Eykyn TR, Andia ME, Flögel U, Phinikaridou A, Shah AM, Botnar RM.

Circ Cardiovasc Imaging. 2018 Nov;11(11). pii: e007453. doi: 10.1161/CIRCIMAGING.117.007453. Epub 2018 Nov 15.

PMID:
30524648
6.

Dissociation of 19F and fluorescence signal upon cellular uptake of dual-contrast perfluorocarbon nanoemulsions.

Bouvain P, Flocke V, Krämer W, Schubert R, Schrader J, Flögel U, Temme S.

MAGMA. 2019 Feb;32(1):133-145. doi: 10.1007/s10334-018-0723-7. Epub 2018 Nov 29.

PMID:
30498884
7.

IL-23R Signaling Plays No Role in Myocardial Infarction.

Engelowski E, Modares NF, Gorressen S, Bouvain P, Semmler D, Alter C, Ding Z, Flögel U, Schrader J, Xu H, Lang PA, Fischer J, Floss DM, Scheller J.

Sci Rep. 2018 Nov 20;8(1):17078. doi: 10.1038/s41598-018-35188-8.

8.

Longitudinal 19F magnetic resonance imaging of brain oxygenation in a mouse model of vascular cognitive impairment using a cryogenic radiofrequency coil.

Khalil AA, Mueller S, Foddis M, Mosch L, Lips J, Przesdzing I, Temme S, Flögel U, Dirnagl U, Boehm-Sturm P.

MAGMA. 2019 Feb;32(1):105-114. doi: 10.1007/s10334-018-0712-x. Epub 2018 Nov 12.

PMID:
30421249
9.

In vivo 19F MR inflammation imaging after myocardial infarction in a large animal model at 3 T.

Rothe M, Jahn A, Weiss K, Hwang JH, Szendroedi J, Kelm M, Schrader J, Roden M, Flögel U, Bönner F.

MAGMA. 2019 Feb;32(1):5-13. doi: 10.1007/s10334-018-0714-8. Epub 2018 Nov 12.

PMID:
30421248
10.

Synthetic Cargo Internalization Receptor System for Nanoparticle Tracking of Individual Cell Populations by Fluorine Magnetic Resonance Imaging.

Temme S, Baran P, Bouvain P, Grapentin C, Krämer W, Knebel B, Al-Hasani H, Moll JM, Floss D, Schrader J, Schubert R, Flögel U, Scheller J.

ACS Nano. 2018 Nov 27;12(11):11178-11192. doi: 10.1021/acsnano.8b05698. Epub 2018 Nov 5.

PMID:
30372619
11.

Insulin Resistance and Vulnerability to Cardiac Ischemia.

Jelenik T, Flögel U, Álvarez-Hernández E, Scheiber D, Zweck E, Ding Z, Rothe M, Mastrototaro L, Kohlhaas V, Kotzka J, Knebel B, Müller-Wieland D, Moellendorf S, Gödecke A, Kelm M, Westenfeld R, Roden M, Szendroedi J.

Diabetes. 2018 Dec;67(12):2695-2702. doi: 10.2337/db18-0449. Epub 2018 Sep 26.

12.

Graves' orbitopathy occurs sex-independently in an autoimmune hyperthyroid mouse model.

Schlüter A, Flögel U, Diaz-Cano S, Görtz GE, Stähr K, Oeverhaus M, Plöhn S, Mattheis S, Moeller LC, Lang S, Bechrakis NE, Banga JP, Eckstein A, Berchner-Pfannschmidt U.

Sci Rep. 2018 Aug 30;8(1):13096. doi: 10.1038/s41598-018-31253-4.

13.

Nrf2 Deficiency Unmasks the Significance of Nitric Oxide Synthase Activity for Cardioprotection.

Erkens R, Suvorava T, Sutton TR, Fernandez BO, Mikus-Lelinska M, Barbarino F, Flögel U, Kelm M, Feelisch M, Cortese-Krott MM.

Oxid Med Cell Longev. 2018 Apr 30;2018:8309698. doi: 10.1155/2018/8309698. eCollection 2018.

14.

Echocardiographic Analysis of Cardiac Function after Infarction in Mice: Validation of Single-Plane Long-Axis View Measurements and the Bi-Plane Simpson Method.

Heinen A, Raupach A, Behmenburg F, Hölscher N, Flögel U, Kelm M, Kaisers W, Nederlof R, Huhn R, Gödecke A.

Ultrasound Med Biol. 2018 Jul;44(7):1544-1555. doi: 10.1016/j.ultrasmedbio.2018.03.020. Epub 2018 Apr 26.

PMID:
29706407
15.

Targeting sphingosine-1-phosphate lyase as an anabolic therapy for bone loss.

Weske S, Vaidya M, Reese A, von Wnuck Lipinski K, Keul P, Bayer JK, Fischer JW, Flögel U, Nelsen J, Epple M, Scatena M, Schwedhelm E, Dörr M, Völzke H, Moritz E, Hannemann A, Rauch BH, Gräler MH, Heusch G, Levkau B.

Nat Med. 2018 May;24(5):667-678. doi: 10.1038/s41591-018-0005-y. Epub 2018 Apr 16.

PMID:
29662200
16.

Multimodal assessment of orbital immune cell infiltration and tissue remodeling during development of graves disease by 1 H19 F MRI.

Flögel U, Schlüter A, Jacoby C, Temme S, Banga JP, Eckstein A, Schrader J, Berchner-Pfannschmidt U.

Magn Reson Med. 2018 Aug;80(2):711-718. doi: 10.1002/mrm.27064. Epub 2018 Jan 27.

PMID:
29377287
17.

Biomedical 19F MRI Using Perfluorocarbons.

Güden-Silber T, Temme S, Jacoby C, Flögel U.

Methods Mol Biol. 2018;1718:235-257. doi: 10.1007/978-1-4939-7531-0_14.

PMID:
29341012
18.

Genetic immunization with mouse thyrotrophin hormone receptor plasmid breaks self-tolerance for a murine model of autoimmune thyroid disease and Graves' orbitopathy.

Schlüter A, Horstmann M, Diaz-Cano S, Plöhn S, Stähr K, Mattheis S, Oeverhaus M, Lang S, Flögel U, Berchner-Pfannschmidt U, Eckstein A, Banga JP.

Clin Exp Immunol. 2018 Mar;191(3):255-267. doi: 10.1111/cei.13075. Epub 2017 Nov 17.

19.

Cardiovascular Magnetic Resonance Relaxometry Predicts Regional Functional Outcome After Experimental Myocardial Infarction.

Haberkorn SM, Jacoby C, Ding Z, Keul P, Bönner F, Polzin A, Levkau B, Schrader J, Kelm M, Flögel U.

Circ Cardiovasc Imaging. 2017 Aug;10(8). pii: e006025. doi: 10.1161/CIRCIMAGING.116.006025.

PMID:
28790121
20.

Mechanisms of Insulin Resistance in Primary and Secondary Nonalcoholic Fatty Liver.

Jelenik T, Kaul K, Séquaris G, Flögel U, Phielix E, Kotzka J, Knebel B, Fahlbusch P, Hörbelt T, Lehr S, Reinbeck AL, Müller-Wieland D, Esposito I, Shulman GI, Szendroedi J, Roden M.

Diabetes. 2017 Aug;66(8):2241-2253. doi: 10.2337/db16-1147. Epub 2017 May 10.

21.

Opening of calcium-activated potassium channels improves long-term left-ventricular function after coronary artery occlusion in mice.

Behmenburg F, Hölscher N, Flögel U, Hollmann MW, Heinen A, Huhn R.

Int J Cardiol. 2017 Aug 15;241:351-357. doi: 10.1016/j.ijcard.2017.04.084. Epub 2017 Apr 27.

PMID:
28487150
22.

CD73 on T Cells Orchestrates Cardiac Wound Healing After Myocardial Infarction by Purinergic Metabolic Reprogramming.

Borg N, Alter C, Görldt N, Jacoby C, Ding Z, Steckel B, Quast C, Bönner F, Friebe D, Temme S, Flögel U, Schrader J.

Circulation. 2017 Jul 18;136(3):297-313. doi: 10.1161/CIRCULATIONAHA.116.023365. Epub 2017 Apr 21.

PMID:
28432149
23.

A novel physiological role for cardiac myoglobin in lipid metabolism.

Hendgen-Cotta UB, Esfeld S, Coman C, Ahrends R, Klein-Hitpass L, Flögel U, Rassaf T, Totzeck M.

Sci Rep. 2017 Feb 23;7:43219. doi: 10.1038/srep43219.

24.

Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.

Haddad S, Wang Y, Galy B, Korf-Klingebiel M, Hirsch V, Baru AM, Rostami F, Reboll MR, Heineke J, Flögel U, Groos S, Renner A, Toischer K, Zimmermann F, Engeli S, Jordan J, Bauersachs J, Hentze MW, Wollert KC, Kempf T.

Eur Heart J. 2017 Feb 1;38(5):362-372. doi: 10.1093/eurheartj/ehw333.

PMID:
27545647
25.

Characterization of perfluorocarbon relaxation times and their influence on the optimization of fluorine-19 MRI at 3 tesla.

Colotti R, Bastiaansen JAM, Wilson A, Flögel U, Gonzales C, Schwitter J, Stuber M, van Heeswijk RB.

Magn Reson Med. 2017 Jun;77(6):2263-2271. doi: 10.1002/mrm.26317. Epub 2016 Jul 6.

PMID:
27385530
26.

Impact of dietary nitrate on age-related diastolic dysfunction.

Rammos C, Hendgen-Cotta UB, Totzeck M, Pohl J, Lüdike P, Flögel U, Deenen R, Köhrer K, French BA, Gödecke A, Kelm M, Rassaf T.

Eur J Heart Fail. 2016 Jun;18(6):599-610. doi: 10.1002/ejhf.535. Epub 2016 Apr 26.

27.

Myocardial T2 Mapping Increases Noninvasive Diagnostic Accuracy for Biopsy-Proven Myocarditis.

Bönner F, Spieker M, Haberkorn S, Jacoby C, Flögel U, Schnackenburg B, Horn P, Reinecke P, Neizel-Wittke M, Kelm M, Westenfeld R.

JACC Cardiovasc Imaging. 2016 Dec;9(12):1467-1469. doi: 10.1016/j.jcmg.2015.11.014. Epub 2016 Apr 13. No abstract available.

28.

Epicardium-Derived Cells Formed After Myocardial Injury Display Phagocytic Activity Permitting In Vivo Labeling and Tracking.

Ding Z, Temme S, Quast C, Friebe D, Jacoby C, Zanger K, Bidmon HJ, Grapentin C, Schubert R, Flögel U, Schrader J.

Stem Cells Transl Med. 2016 May;5(5):639-50. doi: 10.5966/sctm.2015-0159. Epub 2016 Apr 7.

29.

Sexual dimorphism of lipid metabolism in very long-chain acyl-CoA dehydrogenase deficient (VLCAD-/-) mice in response to medium-chain triglycerides (MCT).

Tucci S, Flögel U, Spiekerkoetter U.

Biochim Biophys Acta. 2015 Jul;1852(7):1442-50. doi: 10.1016/j.bbadis.2015.04.009. Epub 2015 Apr 15.

30.

Monocyte imaging after myocardial infarction with 19F MRI at 3 T: a pilot study in explanted porcine hearts.

Bönner F, Merx MW, Klingel K, Begovatz P, Flögel U, Sager M, Temme S, Jacoby C, Salehi Ravesh M, Grapentin C, Schubert R, Bunke J, Roden M, Kelm M, Schrader J.

Eur Heart J Cardiovasc Imaging. 2015 Jun;16(6):612-20. doi: 10.1093/ehjci/jev008. Epub 2015 Mar 1.

PMID:
25733209
31.

Noninvasive Imaging of Early Venous Thrombosis by 19F Magnetic Resonance Imaging With Targeted Perfluorocarbon Nanoemulsions.

Temme S, Grapentin C, Quast C, Jacoby C, Grandoch M, Ding Z, Owenier C, Mayenfels F, Fischer JW, Schubert R, Schrader J, Flögel U.

Circulation. 2015 Apr 21;131(16):1405-14. doi: 10.1161/CIRCULATIONAHA.114.010962. Epub 2015 Feb 19.

PMID:
25700177
32.

Myocardial T2 mapping reveals age- and sex-related differences in volunteers.

Bönner F, Janzarik N, Jacoby C, Spieker M, Schnackenburg B, Range F, Butzbach B, Haberkorn S, Westenfeld R, Neizel-Wittke M, Flögel U, Kelm M.

J Cardiovasc Magn Reson. 2015 Feb 6;17(1):9. doi: 10.1186/s12968-015-0118-0.

33.

Fluorine MR Imaging of Inflammation in Atherosclerotic Plaque in Vivo.

van Heeswijk RB, Pellegrin M, Flögel U, Gonzales C, Aubert JF, Mazzolai L, Schwitter J, Stuber M.

Radiology. 2015 May;275(2):421-9. doi: 10.1148/radiol.14141371. Epub 2014 Dec 12.

34.

Growth and metastasis of B16-F10 melanoma cells is not critically dependent on host CD73 expression in mice.

Burghoff S, Gong X, Viethen C, Jacoby C, Flögel U, Bongardt S, Schorr A, Hippe A, Homey B, Schrader J.

BMC Cancer. 2014 Dec 2;14:898. doi: 10.1186/1471-2407-14-898.

35.

Multifunctional MR monitoring of the healing process after myocardial infarction.

Bönner F, Jacoby C, Temme S, Borg N, Ding Z, Schrader J, Flögel U.

Basic Res Cardiol. 2014;109(5):430. doi: 10.1007/s00395-014-0430-0. Epub 2014 Aug 7.

PMID:
25098936
36.

Loss of UCP2 attenuates mitochondrial dysfunction without altering ROS production and uncoupling activity.

Kukat A, Dogan SA, Edgar D, Mourier A, Jacoby C, Maiti P, Mauer J, Becker C, Senft K, Wibom R, Kudin AP, Hultenby K, Flögel U, Rosenkranz S, Ricquier D, Kunz WS, Trifunovic A.

PLoS Genet. 2014 Jun 19;10(6):e1004385. doi: 10.1371/journal.pgen.1004385. eCollection 2014 Jun.

37.

RIP3, a kinase promoting necroptotic cell death, mediates adverse remodelling after myocardial infarction.

Luedde M, Lutz M, Carter N, Sosna J, Jacoby C, Vucur M, Gautheron J, Roderburg C, Borg N, Reisinger F, Hippe HJ, Linkermann A, Wolf MJ, Rose-John S, Lüllmann-Rauch R, Adam D, Flögel U, Heikenwalder M, Luedde T, Frey N.

Cardiovasc Res. 2014 Jul 15;103(2):206-16. doi: 10.1093/cvr/cvu146. Epub 2014 Jun 11.

38.

Development and pathomechanisms of cardiomyopathy in very long-chain acyl-CoA dehydrogenase deficient (VLCAD(-/-)) mice.

Tucci S, Flögel U, Hermann S, Sturm M, Schäfers M, Spiekerkoetter U.

Biochim Biophys Acta. 2014 May;1842(5):677-85. doi: 10.1016/j.bbadis.2014.02.001. Epub 2014 Feb 12.

39.

Probing different perfluorocarbons for in vivo inflammation imaging by 19F MRI: image reconstruction, biological half-lives and sensitivity.

Jacoby C, Temme S, Mayenfels F, Benoit N, Krafft MP, Schubert R, Schrader J, Flögel U.

NMR Biomed. 2014 Mar;27(3):261-71. doi: 10.1002/nbm.3059. Epub 2013 Dec 19.

PMID:
24353148
40.

Technical advance: monitoring the trafficking of neutrophil granulocytes and monocytes during the course of tissue inflammation by noninvasive 19F MRI.

Temme S, Jacoby C, Ding Z, Bönner F, Borg N, Schrader J, Flögel U.

J Leukoc Biol. 2014 Apr;95(4):689-97. doi: 10.1189/jlb.0113032. Epub 2013 Dec 6.

PMID:
24319285
41.

Visualization of immune cell infiltration in experimental viral myocarditis by (19)F MRI in vivo.

Jacoby C, Borg N, Heusch P, Sauter M, Bönner F, Kandolf R, Klingel K, Schrader J, Flögel U.

MAGMA. 2014 Feb;27(1):101-6. doi: 10.1007/s10334-013-0391-6. Epub 2013 Jul 4.

PMID:
23824166
42.

Ecto-5'-nucleotidase on immune cells protects from adverse cardiac remodeling.

Bönner F, Borg N, Jacoby C, Temme S, Ding Z, Flögel U, Schrader J.

Circ Res. 2013 Jul 19;113(3):301-12. doi: 10.1161/CIRCRESAHA.113.300180. Epub 2013 May 29.

PMID:
23720442
43.

Deletion of CD73 promotes dyslipidemia and intramyocellular lipid accumulation in muscle of mice.

Burghoff S, Flögel U, Bongardt S, Burkart V, Sell H, Tucci S, Ikels K, Eberhard D, Kern M, Klöting N, Eckel J, Schrader J.

Arch Physiol Biochem. 2013 May;119(2):39-51. doi: 10.3109/13813455.2012.755547. Epub 2013 Feb 11.

PMID:
23398498
44.

Lack of ecto-5'-nucleotidase (CD73) promotes arteriogenesis.

Böring YC, Flögel U, Jacoby C, Heil M, Schaper W, Schrader J.

Cardiovasc Res. 2013 Jan 1;97(1):88-96. doi: 10.1093/cvr/cvs286. Epub 2012 Sep 12.

PMID:
22977005
45.

Selective activation of adenosine A2A receptors on immune cells by a CD73-dependent prodrug suppresses joint inflammation in experimental rheumatoid arthritis.

Flögel U, Burghoff S, van Lent PL, Temme S, Galbarz L, Ding Z, El-Tayeb A, Huels S, Bönner F, Borg N, Jacoby C, Müller CE, van den Berg WB, Schrader J.

Sci Transl Med. 2012 Aug 8;4(146):146ra108. doi: 10.1126/scitranslmed.3003717.

46.

Fluorine-19 magnetic resonance angiography of the mouse.

van Heeswijk RB, Pilloud Y, Flögel U, Schwitter J, Stuber M.

PLoS One. 2012;7(7):e42236. doi: 10.1371/journal.pone.0042236. Epub 2012 Jul 27. Erratum in: PLoS One. 2012;7(8): doi/10.1371/annotation/533f969f-0337-4145-906a-565cb11bfa8a.

47.

19F magnetic resonance imaging of endogenous macrophages in inflammation.

Temme S, Bönner F, Schrader J, Flögel U.

Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2012 May-Jun;4(3):329-43. doi: 10.1002/wnan.1163. Epub 2012 Feb 21. Review.

PMID:
22354793
48.

Development of a growing rat model for the in vivo assessment of engineered aortic conduits.

Assmann A, Akhyari P, Delfs C, Flögel U, Jacoby C, Kamiya H, Lichtenberg A.

J Surg Res. 2012 Aug;176(2):367-75. doi: 10.1016/j.jss.2011.10.009. Epub 2011 Nov 4.

PMID:
22172135
49.

MR for the investigation of murine vasculature.

Jacoby C, Flögel U.

Methods Mol Biol. 2011;771:439-56. doi: 10.1007/978-1-61779-219-9_23.

PMID:
21874492
50.

Methods employed for induction and analysis of experimental myocardial infarction in mice.

Borst O, Ochmann C, Schönberger T, Jacoby C, Stellos K, Seizer P, Flögel U, Lang F, Gawaz M.

Cell Physiol Biochem. 2011;28(1):1-12. doi: 10.1159/000331708. Epub 2011 Aug 16. Review.

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