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Year Number of Results
1999 1
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19 results

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Page 1
Genomic Classification and Prognosis in Acute Myeloid Leukemia.
Papaemmanuil E, Gerstung M, Bullinger L, Gaidzik VI, Paschka P, Roberts ND, Potter NE, Heuser M, Thol F, Bolli N, Gundem G, Van Loo P, Martincorena I, Ganly P, Mudie L, McLaren S, O'Meara S, Raine K, Jones DR, Teague JW, Butler AP, Greaves MF, Ganser A, Döhner K, Schlenk RF, Döhner H, Campbell PJ. Papaemmanuil E, et al. N Engl J Med. 2016 Jun 9;374(23):2209-2221. doi: 10.1056/NEJMoa1516192. N Engl J Med. 2016. PMID: 27276561 Free PMC article. Clinical Trial.
FIZ1 is expressed during photoreceptor maturation, and synergizes with NRL and CRX at rod-specific promoters in vitro.
Mali RS, Zhang X, Hoerauf W, Doyle D, Devitt J, Loffreda-Wren J, Mitton KP. Mali RS, et al. Exp Eye Res. 2007 Feb;84(2):349-60. doi: 10.1016/j.exer.2006.10.009. Epub 2006 Dec 4. Exp Eye Res. 2007. PMID: 17141759 Free PMC article.
Rhodopsin). As part of an ongoing exploration of FIZ1's role in neural retina, in vivo, we have taken the first look at FIZ1 expression in the developing mouse retina during the retinal maturation period. ...In the case of the Rho promoter, FIZ1 synergized wh …
Rhodopsin). As part of an ongoing exploration of FIZ1's role in neural retina, in vivo, we have taken the first look at FIZ1 e …
FIZ1 is part of the regulatory protein complex on active photoreceptor-specific gene promoters in vivo.
Mali RS, Peng GH, Zhang X, Dang L, Chen S, Mitton KP. Mali RS, et al. BMC Mol Biol. 2008 Oct 14;9:87. doi: 10.1186/1471-2199-9-87. BMC Mol Biol. 2008. PMID: 18854042 Free PMC article.
BACKGROUND: FIZ1 (Flt-3 Interacting Zinc-finger) is a broadly expressed protein of unknown function. ...FIZ1 complexes with CRX or NRL on known NRL- and CRX-responsive elements, as shown by electrophoretic mobility shift assays with FIZ1 antibody. ...
BACKGROUND: FIZ1 (Flt-3 Interacting Zinc-finger) is a broadly expressed protein of unknown function. ...FIZ1 complexes with CR …
Fiz1, a novel zinc finger protein interacting with the receptor tyrosine kinase Flt3.
Wolf I, Rohrschneider LR. Wolf I, et al. J Biol Chem. 1999 Jul 23;274(30):21478-84. doi: 10.1074/jbc.274.30.21478. J Biol Chem. 1999. PMID: 10409713 Free article.
Fiz1 mRNA is expressed in all murine cell lines and tissues tested. Anti-Fiz1 antibodies recognize a 60-kDa protein, which is localized in the nucleus as well as in the cytoplasm. ...
Fiz1 mRNA is expressed in all murine cell lines and tissues tested. Anti-Fiz1 antibodies recognize a 60-kDa protein, which is
Defects in dynamics and functions of actin filament in Arabidopsis caused by the dominant-negative actin fiz1-induced fragmentation of actin filament.
Kato T, Morita MT, Tasaka M. Kato T, et al. Plant Cell Physiol. 2010 Feb;51(2):333-8. doi: 10.1093/pcp/pcp189. Epub 2010 Jan 3. Plant Cell Physiol. 2010. PMID: 20047880
We isolated frizzy1 (fiz1), a novel dominant actin mutant from Arabidopsis. In the fiz1 mutant, Glu272 was substituted with lysine in the hydrophobic loop of ACT8, which is very important for the polymerization. Live imaging of actin filaments revealed that the f
We isolated frizzy1 (fiz1), a novel dominant actin mutant from Arabidopsis. In the fiz1 mutant, Glu272 was substituted with ly …
Dual retrovirus integration tagging: identification of new signaling molecules Fiz1 and Hipk2 that are involved in the IL-7 signaling pathway in B lymphoblastic lymphomas.
Tsuruyama T, Imai Y, Takeuchi H, Hiratsuka T, Maruyama Y, Kanaya K, Kaszynski R, Jin G, Okuno T, Ozeki M, Nakamura T, Takakuwa T, Manabe T, Tamaki K, Hiai H. Tsuruyama T, et al. J Leukoc Biol. 2010 Jul;88(1):107-16. doi: 10.1189/jlb.1109748. Epub 2010 Apr 1. J Leukoc Biol. 2010. PMID: 20360400
In lymphomas with both integrations into Stat5a and Fiz1, increases in phosphorylated STAT5A and expression of c-Myc, a target gene of STAT5A, were observed following stimulation of the FLT3. ...In conclusion, FLT3 and CD43 signaling pathways involve STAT5A via Fiz1
In lymphomas with both integrations into Stat5a and Fiz1, increases in phosphorylated STAT5A and expression of c-Myc, a target gene o …
Interaction of retinal bZIP transcription factor NRL with Flt3-interacting zinc-finger protein Fiz1: possible role of Fiz1 as a transcriptional repressor.
Mitton KP, Swain PK, Khanna H, Dowd M, Apel IJ, Swaroop A. Mitton KP, et al. Hum Mol Genet. 2003 Feb 15;12(4):365-73. doi: 10.1093/hmg/ddg035. Hum Mol Genet. 2003. PMID: 12566383
Fiz1 suppressed NRL- but not CRX-mediated transactivation of rhodopsin promoter activity in transiently transfected CV1 cells. The mRNA and the protein for both Fiz1 and its only other known interacting protein Flt3, a receptor tyrosine kinase, are expressed in the
Fiz1 suppressed NRL- but not CRX-mediated transactivation of rhodopsin promoter activity in transiently transfected CV1 cells. The mR
Dissection of a novel autocrine signaling pathway via quantitative secretome and interactome mapping.
Larivière N, Law J, Trinkle-Mulcahy L. Larivière N, et al. J Proteome Res. 2014 Jul 3;13(7):3432-43. doi: 10.1021/pr500392m. Epub 2014 Jun 23. J Proteome Res. 2014. PMID: 24956037
Utilizing quantitative SILAC-based secretome analysis, we identified the insulin growth factor binding protein IGFBP3 as the key mediating factor, demonstrating that elevated FIZ1 levels promote increased IGFBP3 expression and secretion and a concurrent increased sensitivi …
Utilizing quantitative SILAC-based secretome analysis, we identified the insulin growth factor binding protein IGFBP3 as the key mediating f …
Leukemia inhibitory factor blocks expression of Crx and Nrl transcription factors to inhibit photoreceptor differentiation.
Graham DR, Overbeek PA, Ash JD. Graham DR, et al. Invest Ophthalmol Vis Sci. 2005 Jul;46(7):2601-10. doi: 10.1167/iovs.05-0129. Invest Ophthalmol Vis Sci. 2005. PMID: 15980254
LIF also reduced the expression of Crx, Nrl, and Nr2e3, and upregulated the expression of transcription inhibitors Baf and Fiz1. CONCLUSIONS: LIF expression did not appear to alter photoreceptor cell fate specification, but it inhibited subsequent differentiation. ...
LIF also reduced the expression of Crx, Nrl, and Nr2e3, and upregulated the expression of transcription inhibitors Baf and Fiz1. CONC …
19 results