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Items: 33


Sex Differences in IL-33-Induced STAT6-Dependent Type 2 Airway Inflammation.

Zhao H, Moarbes V, Gaudreault V, Shan J, Aldossary H, Cyr L, Fixman ED.

Front Immunol. 2019 May 1;10:859. doi: 10.3389/fimmu.2019.00859. eCollection 2019.


STAT6 inhibitory peptide reduces dendritic cell migration to the lymph nodes to control Th2 adaptive immunity in the mouse lung.

Lee S, Shan J, Aldossary H, Gaudreault V, Bazett M, Fixman ED.

Eur J Immunol. 2019 Jan;49(1):157-169. doi: 10.1002/eji.201847534. Epub 2018 Dec 7.


Glycolytic metabolism is essential for CCR7 oligomerization and dendritic cell migration.

Guak H, Al Habyan S, Ma EH, Aldossary H, Al-Masri M, Won SY, Ying T, Fixman ED, Jones RG, McCaffrey LM, Krawczyk CM.

Nat Commun. 2018 Jun 25;9(1):2463. doi: 10.1038/s41467-018-04804-6.


Neonatal Immunity, Respiratory Virus Infections, and the Development of Asthma.

Restori KH, Srinivasa BT, Ward BJ, Fixman ED.

Front Immunol. 2018 Jun 4;9:1249. doi: 10.3389/fimmu.2018.01249. eCollection 2018. Review.


Semaphorin 4C Protects against Allergic Inflammation: Requirement of Regulatory CD138+ Plasma Cells.

Xue D, Kaufman GN, Dembele M, Beland M, Massoud AH, Mindt BC, Fiter R, Fixman ED, Martin JG, Friedel RH, Divangahi M, Fritz JH, Mazer BD.

J Immunol. 2017 Jan 1;198(1):71-81. Epub 2016 Nov 23.


STAT6 inhibitory peptide given during RSV infection of neonatal mice reduces exacerbated airway responses upon adult reinfection.

Srinivasa BT, Restori KH, Shan J, Cyr L, Xing L, Lee S, Ward BJ, Fixman ED.

J Leukoc Biol. 2017 Feb;101(2):519-529. doi: 10.1189/jlb.4A0215-062RR. Epub 2016 Aug 26.


Adjuvant-dependent regulation of interleukin-17 expressing γδ T cells and inhibition of Th2 responses in allergic airways disease.

Nakada EM, Shan J, Kinyanjui MW, Fixman ED.

Respir Res. 2014 Aug 14;15:90. doi: 10.1186/s12931-014-0090-5.


Inhibition of STAT6 during vaccination with formalin-inactivated RSV prevents induction of Th2-cell-biased airway disease.

Srinivasa BT, Fixman ED, Ward BJ.

Eur J Immunol. 2014 Aug;44(8):2349-59. doi: 10.1002/eji.201344206. Epub 2014 Jun 5.


CD4+ T cells enhance the unloaded shortening velocity of airway smooth muscle by altering the contractile protein expression.

Matusovsky OS, Nakada EM, Kachmar L, Fixman ED, Lauzon AM.

J Physiol. 2014 Jul 15;592(14):2999-3012. doi: 10.1113/jphysiol.2014.270843. Epub 2014 Mar 31.


Dose-dependent effects of IL-17 on IL-13-induced airway inflammatory responses and airway hyperresponsiveness.

Kinyanjui MW, Shan J, Nakada EM, Qureshi ST, Fixman ED.

J Immunol. 2013 Apr 15;190(8):3859-68. doi: 10.4049/jimmunol.1200506. Epub 2013 Mar 18.


Developments in the field of allergy in 2011 through the eyes of Clinical and Experimental Allergy.

Arshad SH, Dharmage SC, Ferreira F, Fixman ED, Gadermaier G, Hauser M, Sampson AP, Teran LM, Wallner M, Wardlaw AJ.

Clin Exp Allergy. 2012 Dec;42(12):1697-723. doi: 10.1111/cea.12037. Review.


Platelet-derived growth factor and transforming growth factor-beta modulate the expression of matrix metalloproteinases and migratory function of human airway smooth muscle cells.

Ito I, Fixman ED, Asai K, Yoshida M, Gounni AS, Martin JG, Hamid Q.

Clin Exp Allergy. 2009 Sep;39(9):1370-80. doi: 10.1111/j.1365-2222.2009.03293.x. Epub 2009 Jun 11.


Cell-penetrating peptides and proteins: new inhibitors of allergic airways disease.

Kinyanjui MW, Fixman ED.

Can J Physiol Pharmacol. 2008 Jan-Feb;86(1-2):1-7. doi: 10.1139/y07-125. Review.


T-helper type 2-dependent early recruitment of antigen non-specific CD4+ T cells in experimental asthma.

Kinyanjui MW, Tamaoka M, Fixman ED.

Clin Exp Allergy. 2007 Oct;37(10):1455-66.


Inhibition of experimental allergic airways disease by local application of a cell-penetrating dominant-negative STAT-6 peptide.

McCusker CT, Wang Y, Shan J, Kinyanjui MW, Villeneuve A, Michael H, Fixman ED.

J Immunol. 2007 Aug 15;179(4):2556-64.


Basic mechanisms of development of airway structural changes in asthma.

Fixman ED, Stewart A, Martin JG.

Eur Respir J. 2007 Feb;29(2):379-89. Review.


Enhanced transduction of antigen-stimulated T lymphocytes with recombinant retroviruses concentrated by centrifugal filtration.

Kinyanjui MW, Ramos-Barbón D, Villeneuve A, Fixman ED.

J Immunol Methods. 2006 Jul 31;314(1-2):80-9. Epub 2006 Jun 30.


Endothelin-1 regulates proliferative responses, both alone and synergistically with PDGF, in rat tracheal smooth muscle cells.

Yahiaoui L, Villeneuve A, Valderrama-Carvajal H, Burke F, Fixman ED.

Cell Physiol Biochem. 2006;17(1-2):37-46. Epub 2006 Feb 7.


Antigen-specific CD4+ T cells drive airway smooth muscle remodeling in experimental asthma.

Ramos-Barbón D, Presley JF, Hamid QA, Fixman ED, Martin JG.

J Clin Invest. 2005 Jun;115(6):1580-9. Epub 2005 May 2.


Proliferative aspects of airway smooth muscle.

Hirst SJ, Martin JG, Bonacci JV, Chan V, Fixman ED, Hamid QA, Herszberg B, Lavoie JP, McVicker CG, Moir LM, Nguyen TT, Peng Q, Ramos-Barbón D, Stewart AG.

J Allergy Clin Immunol. 2004 Aug;114(2 Suppl):S2-17. Review.


Src modulates serotonin-induced calcium signaling by regulating phosphatidylinositol 4,5-bisphosphate.

Tolloczko B, Turkewitsch P, Choudry S, Bisotto S, Fixman ED, Martin JG.

Am J Physiol Lung Cell Mol Physiol. 2002 Jun;282(6):L1305-13.


Association of the multisubstrate docking protein Gab1 with the hepatocyte growth factor receptor requires a functional Grb2 binding site involving tyrosine 1356.

Nguyen L, Holgado-Madruga M, Maroun C, Fixman ED, Kamikura D, Fournier T, Charest A, Tremblay ML, Wong AJ, Park M.

J Biol Chem. 1997 Aug 15;272(33):20811-9.


Efficient cellular transformation by the Met oncoprotein requires a functional Grb2 binding site and correlates with phosphorylation of the Grb2-associated proteins, Cbl and Gab1.

Fixman ED, Holgado-Madruga M, Nguyen L, Kamikura DM, Fournier TM, Wong AJ, Park M.

J Biol Chem. 1997 Aug 8;272(32):20167-72.


A replication function associated with the activation domain of the Epstein-Barr virus Zta transactivator.

Sarisky RT, Gao Z, Lieberman PM, Fixman ED, Hayward GS, Hayward SD.

J Virol. 1996 Dec;70(12):8340-7.


Pathways downstream of Shc and Grb2 are required for cell transformation by the tpr-Met oncoprotein.

Fixman ED, Fournier TM, Kamikura DM, Naujokas MA, Park M.

J Biol Chem. 1996 May 31;271(22):13116-22.


Efficient cell transformation by the Tpr-Met oncoprotein is dependent upon tyrosine 489 in the carboxy-terminus.

Fixman ED, Naujokas MA, Rodrigues GA, Moran MF, Park M.

Oncogene. 1995 Jan 19;10(2):237-49.


trans-acting requirements for replication of Epstein-Barr virus ori-Lyt.

Fixman ED, Hayward GS, Hayward SD.

J Virol. 1992 Aug;66(8):5030-9.

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