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Items: 1 to 50 of 142

1.

Seasonal Variation in Sediment and Phosphorus Yields in Four Wisconsin Agricultural Watersheds.

Good LW, Carvin R, Lamba J, Fitzpatrick FA.

J Environ Qual. 2019 Jul;48(4):950-958. doi: 10.2134/jeq2019.03.0134.

PMID:
31589695
2.

Influence of myeloperoxidase on colon tumor occurrence in inflamed versus non-inflamed colons of Apc(Min/+) mice.

Al-Salihi M, Reichert E, Fitzpatrick FA.

Redox Biol. 2015 Dec;6:218-225. doi: 10.1016/j.redox.2015.07.013. Epub 2015 Jul 29.

3.

Stream Sediment Sources in Midwest Agricultural Basins with Land Retirement along Channel.

Williamson TN, Christensen VG, Richardson WB, Frey JW, Gellis AC, Kieta KA, Fitzpatrick FA.

J Environ Qual. 2014 Sep;43(5):1624-34. doi: 10.2134/jeq2013.12.0521.

PMID:
25603248
4.

The depletion of DNA methyltransferase-1 and the epigenetic effects of 5-aza-2'deoxycytidine (decitabine) are differentially regulated by cell cycle progression.

Al-Salihi M, Yu M, Burnett DM, Alexander A, Samlowski WE, Fitzpatrick FA.

Epigenetics. 2011 Aug;6(8):1021-8. doi: 10.4161/epi.6.8.16064. Epub 2011 Aug 1.

5.

Alkylation of the tumor suppressor PTEN activates Akt and β-catenin signaling: a mechanism linking inflammation and oxidative stress with cancer.

Covey TM, Edes K, Coombs GS, Virshup DM, Fitzpatrick FA.

PLoS One. 2010 Oct 21;5(10):e13545. doi: 10.1371/journal.pone.0013545.

6.

Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.

Slattery ML, Herrick JS, Lundgreen A, Fitzpatrick FA, Curtin K, Wolff RK.

Carcinogenesis. 2010 Sep;31(9):1604-11. doi: 10.1093/carcin/bgq142. Epub 2010 Jul 9.

7.
8.

Fiberoptic resonance Raman spectroscopy to measure carotenoid oxidative breakdown in live tissues.

Bentz BG, Diaz J, Ring TA, Wade M, Kennington K, Burnett DM, McClane R, Fitzpatrick FA.

Cancer Prev Res (Phila). 2010 Apr;3(4):529-38. doi: 10.1158/1940-6207.CAPR-09-0157. Epub 2010 Mar 30.

9.

Convergence of hormones, inflammation, and energy-related factors: a novel pathway of cancer etiology.

Slattery ML, Fitzpatrick FA.

Cancer Prev Res (Phila). 2009 Nov;2(11):922-30. doi: 10.1158/1940-6207.CAPR-08-0191. Review.

10.

Oxidation of 2-Cys-peroxiredoxins by arachidonic acid peroxide metabolites of lipoxygenases and cyclooxygenase-2.

Cordray P, Doyle K, Edes K, Moos PJ, Fitzpatrick FA.

J Biol Chem. 2007 Nov 9;282(45):32623-9. Epub 2007 Sep 13.

11.

Akt activation by arachidonic acid metabolism occurs via oxidation and inactivation of PTEN tumor suppressor.

Covey TM, Edes K, Fitzpatrick FA.

Oncogene. 2007 Aug 23;26(39):5784-92. Epub 2007 Mar 19.

PMID:
17369849
12.

Thioredoxin reductase is required for the inactivation of tumor suppressor p53 and for apoptosis induced by endogenous electrophiles.

Cassidy PB, Edes K, Nelson CC, Parsawar K, Fitzpatrick FA, Moos PJ.

Carcinogenesis. 2006 Dec;27(12):2538-49. Epub 2006 Jun 15.

PMID:
16777982
14.

Conditional expression of 15-lipoxygenase-1 inhibits the selenoenzyme thioredoxin reductase: modulation of selenoproteins by lipoxygenase enzymes.

Yu MK, Moos PJ, Cassidy P, Wade M, Fitzpatrick FA.

J Biol Chem. 2004 Jul 2;279(27):28028-35. Epub 2004 Apr 27.

15.

Curcumin impairs tumor suppressor p53 function in colon cancer cells.

Moos PJ, Edes K, Mullally JE, Fitzpatrick FA.

Carcinogenesis. 2004 Sep;25(9):1611-7. Epub 2004 Apr 16.

PMID:
15090465
16.

Punaglandins, chlorinated prostaglandins, function as potent Michael receptors to inhibit ubiquitin isopeptidase activity.

Verbitski SM, Mullally JE, Fitzpatrick FA, Ireland CM.

J Med Chem. 2004 Apr 8;47(8):2062-70.

PMID:
15056003
17.

Cyclooxygenase enzymes: regulation and function.

Fitzpatrick FA.

Curr Pharm Des. 2004;10(6):577-88. Review.

PMID:
14965321
18.

The immunopharmacology of paclitaxel (Taxol), docetaxel (Taxotere), and related agents.

Fitzpatrick FA, Wheeler R.

Int Immunopharmacol. 2003 Dec;3(13-14):1699-714. Review.

PMID:
14636822
19.
20.
22.

Inflammation, carcinogenesis and cancer.

Fitzpatrick FA.

Int Immunopharmacol. 2001 Sep;1(9-10):1651-67. Review.

PMID:
11562058
23.

Regulated formation of eicosanoids.

Fitzpatrick FA, Soberman R.

J Clin Invest. 2001 Jun;107(11):1347-51. Review. No abstract available.

24.

Cyclopentenone prostaglandins of the J series inhibit the ubiquitin isopeptidase activity of the proteasome pathway.

Mullally JE, Moos PJ, Edes K, Fitzpatrick FA.

J Biol Chem. 2001 Aug 10;276(32):30366-73. Epub 2001 Jun 4.

25.

Inactivation of wild-type p53 tumor suppressor by electrophilic prostaglandins.

Moos PJ, Edes K, Fitzpatrick FA.

Proc Natl Acad Sci U S A. 2000 Aug 1;97(16):9215-20.

26.

Cyclooxygenase-2 and carcinogenesis.

Prescott SM, Fitzpatrick FA.

Biochim Biophys Acta. 2000 Mar 27;1470(2):M69-78. Review.

PMID:
10722929
28.

Genomics and the discovery of new drug targets.

Jones DA, Fitzpatrick FA.

Curr Opin Chem Biol. 1999 Feb;3(1):71-6. Review.

PMID:
10021407
29.
30.
33.

Nitric oxide modulates the activity of the hemoproteins prostaglandin I2 synthase and thromboxane A2 synthase.

Wade ML, Fitzpatrick FA.

Arch Biochem Biophys. 1997 Nov 15;347(2):174-80.

PMID:
9367522
34.
35.

Tyrosine kinase activity modulates catalysis and translocation of cellular 5-lipoxygenase.

Lepley RA, Muskardin DT, Fitzpatrick FA.

J Biol Chem. 1996 Mar 15;271(11):6179-84.

36.
37.
38.

Suicide inactivation of leukotriene A4 hydrolase/aminopeptidase.

Fitzpatrick FA, Lepley R, Orning L, Duffin K.

Ann N Y Acad Sci. 1994 Nov 15;744:31-8. Review. No abstract available.

PMID:
7825854
40.

Modulation of pulmonary leukotriene formation and perfusion pressure by bestatin, an inhibitor of leukotriene A4 hydrolase.

Muskardin DT, Voelkel NF, Fitzpatrick FA.

Biochem Pharmacol. 1994 Jul 5;48(1):131-7.

PMID:
8043014
41.

Effects of leukotriene A4 on neutrophil activation.

Fitzpatrick FA, Lepley R, Orning L, Duffin K.

Ann N Y Acad Sci. 1994 Apr 18;714:64-74. Review. No abstract available.

PMID:
8017792
42.
44.

Mechanism-based inactivation of leukotriene A4 hydrolase/aminopeptidase by leukotriene A4. Mass spectrometric and kinetic characterization.

Orning L, Gierse J, Duffin K, Bild G, Krivi G, Fitzpatrick FA.

J Biol Chem. 1992 Nov 15;267(32):22733-9.

45.
46.

Do dietary fatty acids affect intra- and intercellular signalling? How might these processes affect thrombosis?

Fitzpatrick FA.

Am J Clin Nutr. 1992 Oct;56(4 Suppl):807S. doi: 10.1093/ajcn/56.4.807s. No abstract available.

PMID:
1414990
47.

Opioid peptides are substrates for the bifunctional enzyme LTA4 hydrolase/aminopeptidase.

Griffin KJ, Gierse J, Krivi G, Fitzpatrick FA.

Prostaglandins. 1992 Sep;44(3):251-7.

PMID:
1410529
48.

Albumins activate peptide hydrolysis by the bifunctional enzyme LTA4 hydrolase/aminopeptidase.

Orning L, Fitzpatrick FA.

Biochemistry. 1992 May 5;31(17):4218-23.

PMID:
1314659
49.
50.

Signal transduction pathways involved in presynaptic receptor-mediated inhibition of dopamine release in rat striatum.

Zahniser NR, Cass WA, Fitzpatrick FA.

Neurochem Int. 1992 Mar;20 Suppl:85S-88S. No abstract available.

PMID:
1365462

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