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Combining an in silico proarrhythmic risk assay with a tPKPD model to predict QTc interval prolongation in the anesthetized Guinea pig assay.

Morissette P, Polak S, Chain A, Zhai J, Imredy JP, Wildey MJ, Travis J, Fitzgerald K, Fanelli P, Passini E, Rodriguez B, Sannajust F, Regan C.

Toxicol Appl Pharmacol. 2020 Jan 22:114883. doi: 10.1016/j.taap.2020.114883. [Epub ahead of print]


Setting precedent: Initial feature variability affects the subsequent precision of regularly varying sound contexts.

Todd J, Frost J, Fitzgerald K, Winkler I.

Psychophysiology. 2020 Jan 23:e13528. doi: 10.1111/psyp.13528. [Epub ahead of print]


Prevalence and associations of prescribing of long-acting reversible contraception by general practitioner registrars: a secondary analysis of ReCEnT data.

Turner R, Tapley A, Sweeney S, Davey A, Holliday E, van Driel M, Henderson K, Ball J, Morgan S, Spike N, FitzGerald K, Magin P.

BMJ Sex Reprod Health. 2020 Jan 21. pii: bmjsrh-2019-200309. doi: 10.1136/bmjsrh-2019-200309. [Epub ahead of print]


Characterization of a conscious, restrained, rabbit CV telemetry model for assessing hemodynamic and ECG risk liabilities in early drug research and development.

Fitzgerald K, Morissette P, Chen L, Bueters T, Chaves A, Regan C, Sannajust F.

J Pharmacol Toxicol Methods. 2019 Sep - Oct;99:106595. doi: 10.1016/j.vascn.2019.05.053. Epub 2019 Oct 17. No abstract available.


Associations between Antiretroviral Drugs on Depressive Symptomatology in Homogenous Subgroups of Women with HIV.

Williams DW, Li Y, Dastgheyb R, Fitzgerald KC, Maki PM, Spence AB, Gustafson DR, Milam J, Sharma A, Adimora AA, Ofotokun I, Fischl MA, Konkle-Parker D, Weber KM, Xu Y, Rubin LH.

J Neuroimmune Pharmacol. 2020 Jan 13. doi: 10.1007/s11481-019-09899-2. [Epub ahead of print]


Cross-sectional study using primary care and cancer registration data to investigate patients with cancer presenting with non-specific symptoms.

Pearson C, Poirier V, Fitzgerald K, Rubin G, Hamilton W.

BMJ Open. 2020 Jan 10;10(1):e033008. doi: 10.1136/bmjopen-2019-033008.


Identification of a Novel Homozygous Multi-Exon Duplication in RYR2 Among Children With Exertion-Related Unexplained Sudden Deaths in the Amish Community.

Tester DJ, Bombei HM, Fitzgerald KK, Giudicessi JR, Pitel BA, Thorland EC, Russell BG, Hamrick SK, Kim CSJ, Haglund-Turnquist CM, Johnsrude CL, Atkins DL, Ochoa Nunez LA, Law I, Temple J, Ackerman MJ.

JAMA Cardiol. 2020 Jan 8. doi: 10.1001/jamacardio.2019.5400. [Epub ahead of print]


TLR2 Dimerization Blockade Allows Generation of Homeostatic Intestinal Macrophages under Acute Colitis Challenge.

Gross-Vered M, Shmuel-Galia L, Zarmi B, Humphries F, Thaiss C, Salame TM, David E, Chappell-Maor L, Fitzgerald KA, Shai Y, Jung S.

J Immunol. 2020 Feb 1;204(3):707-717. doi: 10.4049/jimmunol.1900470. Epub 2019 Dec 27.


Management of urinary tract infection by early-career general practitioners in Australia.

Davey A, Tapley A, Mulquiney K, van Driel M, Fielding A, Holliday E, Ball J, Spike N, FitzGerald K, Magin P.

J Eval Clin Pract. 2019 Dec 25. doi: 10.1111/jep.13340. [Epub ahead of print]


Creating the conditions for change: an NHS perspective.

Fitzgerald K, Biddle L.

J Health Organ Manag. 2019 Dec 19;ahead-of-print(ahead-of-print). doi: 10.1108/JHOM-02-2019-0031.


A Mitochondrial Micropeptide Is Required for Activation of the Nlrp3 Inflammasome.

Bhatta A, Atianand M, Jiang Z, Crabtree J, Blin J, Fitzgerald KA.

J Immunol. 2020 Jan 15;204(2):428-437. doi: 10.4049/jimmunol.1900791. Epub 2019 Dec 13.


Myh11 Lineage Corneal Endothelial Cells and ASCs Populate Corneal Endothelium.

Corliss BA, Ray HC, Mathews C, Fitzgerald K, Doty RW, Smolko CM, Shariff H, Peirce SM, Yates PA.

Invest Ophthalmol Vis Sci. 2019 Dec 2;60(15):5095-5103. doi: 10.1167/iovs.19-27276.


The Onpattro story and the clinical translation of nanomedicines containing nucleic acid-based drugs.

Akinc A, Maier MA, Manoharan M, Fitzgerald K, Jayaraman M, Barros S, Ansell S, Du X, Hope MJ, Madden TD, Mui BL, Semple SC, Tam YK, Ciufolini M, Witzigmann D, Kulkarni JA, van der Meel R, Cullis PR.

Nat Nanotechnol. 2019 Dec;14(12):1084-1087. doi: 10.1038/s41565-019-0591-y. No abstract available.


Improving Interdisciplinary Communication Using a Group Work Program Software Application.

Aufderheide S, Dus JE, Fitzgerald K, Bober M.

Prof Case Manag. 2020 Jan/Feb;25(1):48-52. doi: 10.1097/NCM.0000000000000412. No abstract available.


Nucleus accumbens volume as a predictor of anxiety symptom improvement following CBT and SSRI treatment in two independent samples.

Burkhouse KL, Jagan Jimmy, Defelice N, Klumpp H, Ajilore O, Hosseini B, Fitzgerald KD, Monk CS, Phan KL.

Neuropsychopharmacology. 2020 Feb;45(3):561-569. doi: 10.1038/s41386-019-0575-5. Epub 2019 Nov 22.


Acoustic Parameters for Optimal Ultrasound-Triggered Release from Novel Spinal Hardware Devices.

Delaney LJ, Basgul C, MacDonald DW, Fitzgerald K, Hickok NJ, Kurtz SM, Forsberg F.

Ultrasound Med Biol. 2020 Feb;46(2):350-358. doi: 10.1016/j.ultrasmedbio.2019.10.002. Epub 2019 Nov 13.


Acne in primary care: A cross-sectional analysis.

Brown H, Tapley A, van Driel ML, Davey AR, Holliday E, Ball J, Morgan S, Patsan I, Mulquiney KJ, Spike N, FitzGerald K, Magin P.

Aust J Gen Pract. 2019 Nov;48(11):781-788. doi: 10.31128/AJGP-02-19-4864.


Conducting dietary intervention trials in people with multiple sclerosis: Lessons learned and a path forward.

Fitzgerald KC, Sand IK, Senders A, Spain R, Giesser B, Sullivan P, Baer DJ, LaRocca N, Zackowski K, Mowry EM.

Mult Scler Relat Disord. 2019 Oct 29;37:101478. doi: 10.1016/j.msard.2019.101478. [Epub ahead of print] Review.


Erratum to "Evaluation of a health service adopting proactive approach to reduce high risk of lung cancer: The Liverpool Healthy Lung Programme" [Lung Cancer 134 (August) (2019) 66-71].

Ghimire B, Maroni R, Vulkan D, Shah Z, Gaynor E, Timoney M, Jones L, Arvanitis R, Ledson M, Lukehirst L, Rutherford P, Clarke F, Gardner K, Marcus MW, Hill S, Fidoe D, Mason S, Smith SG, Quaife SL, Fitzgerald K, Poirier V, Duffy SW, Field JK.

Lung Cancer. 2020 Jan;139:224. doi: 10.1016/j.lungcan.2019.10.007. Epub 2019 Nov 2. No abstract available.


Antibiotic stewardship in skin infections: a cross-sectional analysis of early-career GP's management of impetigo.

Heal C, Gorges H, van Driel ML, Tapley A, Davis J, Davey A, Holliday L, Ball J, Najib N, Spike N, FitzGerald K, Magin P.

BMJ Open. 2019 Oct 28;9(10):e031527. doi: 10.1136/bmjopen-2019-031527.


Randomized-controlled trial of a modified Mediterranean dietary program for multiple sclerosis: A pilot study.

Katz Sand I, Benn EKT, Fabian M, Fitzgerald KC, Digga E, Deshpande R, Miller A, Gallo S, Arab L.

Mult Scler Relat Disord. 2019 Nov;36:101403. doi: 10.1016/j.msard.2019.101403. Epub 2019 Sep 24.


hnRNPA2B1: Fueling Antiviral Immunity from the Nucleus.

Humphries F, Fitzgerald KA.

Mol Cell. 2019 Oct 3;76(1):8-10. doi: 10.1016/j.molcel.2019.09.021.


Dietary Sugars Alter Hepatic Fatty Acid Oxidation via Transcriptional and Post-translational Modifications of Mitochondrial Proteins.

Softic S, Meyer JG, Wang GX, Gupta MK, Batista TM, Lauritzen HPMM, Fujisaka S, Serra D, Herrero L, Willoughby J, Fitzgerald K, Ilkayeva O, Newgard CB, Gibson BW, Schilling B, Cohen DE, Kahn CR.

Cell Metab. 2019 Oct 1;30(4):735-753.e4. doi: 10.1016/j.cmet.2019.09.003.


Gasdermins and their role in immunity and inflammation.

Orning P, Lien E, Fitzgerald KA.

J Exp Med. 2019 Nov 4;216(11):2453-2465. doi: 10.1084/jem.20190545. Epub 2019 Sep 23. Review.


Moderation of the relationship between the error-related negativity and anxiety by age and gender in young children: A preliminary investigation.

Ip KI, Liu Y, Moser J, Mannella K, Hruschak J, Bilek E, Muzik M, Rosenblum K, Fitzgerald K.

Dev Cogn Neurosci. 2019 Oct;39:100702. doi: 10.1016/j.dcn.2019.100702. Epub 2019 Aug 19.


Early Predictors of Enteral Autonomy in Pediatric Intestinal Failure Resulting From Short Bowel Syndrome: Development of a Disease Severity Scoring Tool.

Belza C, Fitzgerald K, de Silva N, Avitzur Y, Wales PW.

JPEN J Parenter Enteral Nutr. 2019 Nov;43(8):961-969. doi: 10.1002/jpen.1691. Epub 2019 Aug 28.


Assembling the Inflammasome, Piece by Piece.

Humphries F, Fitzgerald KA.

J Immunol. 2019 Sep 1;203(5):1093-1094. doi: 10.4049/jimmunol.1900764. No abstract available.


General practice registrars' experiences of antenatal care: A cross-sectional analysis.

Pappalardo E, Magin P, Tapley A, Davey A, Holliday EG, Ball J, Spike N, FitzGerald K, Morgan S, van Driel ML.

Aust N Z J Obstet Gynaecol. 2019 Aug 19. doi: 10.1111/ajo.13042. [Epub ahead of print]


The genetic diversity of multiple sclerosis risk among Hispanic and African American populations living in the United States.

Beecham AH, Amezcua L, Chinea A, Manrique CP, Rubi C, Isobe N, Lund BT, Santaniello A, Beecham GW, Burchard EG, Comabella M, Patsopoulos N, Fitzgerald K, Calabresi PA, De Jager P, Conti DV, Delgado SR, Oksenberg JR, McCauley JL.

Mult Scler. 2019 Aug 1:1352458519863764. doi: 10.1177/1352458519863764. [Epub ahead of print]


Aquaporin-4 IgG seropositivity is associated with worse visual outcomes after optic neuritis than MOG-IgG seropositivity and multiple sclerosis, independent of macular ganglion cell layer thinning.

Sotirchos ES, Filippatou A, Fitzgerald KC, Salama S, Pardo S, Wang J, Ogbuokiri E, Cowley NJ, Pellegrini N, Murphy OC, Mealy MA, Prince JL, Levy M, Calabresi PA, Saidha S.

Mult Scler. 2019 Jul 31:1352458519864928. doi: 10.1177/1352458519864928. [Epub ahead of print]


DNA sensing by the cGAS-STING pathway in health and disease.

Motwani M, Pesiridis S, Fitzgerald KA.

Nat Rev Genet. 2019 Nov;20(11):657-674. doi: 10.1038/s41576-019-0151-1. Epub 2019 Jul 29. Review.


Haploinsufficiency of the Notch Ligand DLL1 Causes Variable Neurodevelopmental Disorders.

Fischer-Zirnsak B, Segebrecht L, Schubach M, Charles P, Alderman E, Brown K, Cadieux-Dion M, Cartwright T, Chen Y, Costin C, Fehr S, Fitzgerald KM, Fleming E, Foss K, Ha T, Hildebrand G, Horn D, Liu S, Marco EJ, McDonald M, McWalter K, Race S, Rush ET, Si Y, Saunders C, Slavotinek A, Stockler-Ipsiroglu S, Telegrafi A, Thiffault I, Torti E, Tsai AC, Wang X, Zafar M, Keren B, Kornak U, Boerkoel CF, Mirzaa G, Ehmke N.

Am J Hum Genet. 2019 Sep 5;105(3):631-639. doi: 10.1016/j.ajhg.2019.07.002. Epub 2019 Jul 25.


The prevalence and utility of screening for urinary tract infection at the time of presumed multiple sclerosis relapse.

Fitzgerald KC, Cassard LA, Fox SR, Probasco JC, Cassard SD, Mowry EM.

Mult Scler Relat Disord. 2019 Oct;35:61-66. doi: 10.1016/j.msard.2019.06.038. Epub 2019 Jul 2.


Geophagy among a Cohort of Kenyan Women with Mixed HIV Status: A Longitudinal Analysis.

Miller JD, Fitzgerald KG, Smith AL, Young SL.

Am J Trop Med Hyg. 2019 Sep;101(3):654-660. doi: 10.4269/ajtmh.19-0149.


Simulation can offer a sustainable contribution to clinical education in osteopathy.

Fitzgerald KM, Denning T, Vaughan BR, Fleischmann MJ, Jolly BC.

Chiropr Man Therap. 2019 Jul 10;27:38. doi: 10.1186/s12998-019-0252-0. eCollection 2019.


Evaluation of a health service adopting proactive approach to reduce high risk of lung cancer: The Liverpool Healthy Lung Programme.

Ghimire B, Maroni R, Vulkan D, Shah Z, Gaynor E, Timoney M, Jones L, Arvanitis R, Ledson M, Lukehirst L, Rutherford P, Clarke F, Gardner K, Marcus MW, Hill S, Fidoe D, Mason S, Smith SG, Quaife SL, Fitzgerald K, Poirier V, Duffy SW, Field JK.

Lung Cancer. 2019 Aug;134:66-71. doi: 10.1016/j.lungcan.2019.05.026. Epub 2019 May 29. Erratum in: Lung Cancer. 2020 Jan;139:224.


DeepHarmony: A deep learning approach to contrast harmonization across scanner changes.

Dewey BE, Zhao C, Reinhold JC, Carass A, Fitzgerald KC, Sotirchos ES, Saidha S, Oh J, Pham DL, Calabresi PA, van Zijl PCM, Prince JL.

Magn Reson Imaging. 2019 Dec;64:160-170. doi: 10.1016/j.mri.2019.05.041. Epub 2019 Jul 10.


Early complement genes are associated with visual system degeneration in multiple sclerosis.

Fitzgerald KC, Kim K, Smith MD, Aston SA, Fioravante N, Rothman AM, Krieger S, Cofield SS, Kimbrough DJ, Bhargava P, Saidha S, Whartenby KA, Green AJ, Mowry EM, Cutter GR, Lublin FD, Baranzini SE, De Jager PL, Calabresi PA.

Brain. 2019 Sep 1;142(9):2722-2736. doi: 10.1093/brain/awz188.


Australian general practice registrars and their experience with postpartum consultations: A cross-sectional analysis of prevalence and associations.

Hill S, Tapley A, van Driel ML, Holliday EG, Ball J, Davey A, Patsan I, Spike N, Fitzgerald K, Morgan S, Magin P.

Aust N Z J Obstet Gynaecol. 2019 Jul 7. doi: 10.1111/ajo.13034. [Epub ahead of print]


Investigational RNAi Therapeutic Targeting C5 Is Efficacious in Pre-clinical Models of Myasthenia Gravis.

Kusner LL, Yucius K, Sengupta M, Sprague AG, Desai D, Nguyen T, Charisse K, Kuchimanchi S, Kallanthottathil R, Fitzgerald K, Kaminski HJ, Borodovsky A.

Mol Ther Methods Clin Dev. 2019 May 10;13:484-492. doi: 10.1016/j.omtm.2019.04.009. eCollection 2019 Jun 14.


Mapping Cortical and Subcortical Asymmetry in Obsessive-Compulsive Disorder: Findings From the ENIGMA Consortium.

Kong XZ, Boedhoe PSW, Abe Y, Alonso P, Ameis SH, Arnold PD, Assogna F, Baker JT, Batistuzzo MC, Benedetti F, Beucke JC, Bollettini I, Bose A, Brem S, Brennan BP, Buitelaar J, Calvo R, Cheng Y, Cho KIK, Dallaspezia S, Denys D, Ely BA, Feusner J, Fitzgerald KD, Fouche JP, Fridgeirsson EA, Glahn DC, Gruner P, Gürsel DA, Hauser TU, Hirano Y, Hoexter MQ, Hu H, Huyser C, James A, Jaspers-Fayer F, Kathmann N, Kaufmann C, Koch K, Kuno M, Kvale G, Kwon JS, Lazaro L, Liu Y, Lochner C, Marques P, Marsh R, Martínez-Zalacaín I, Mataix-Cols D, Medland SE, Menchón JM, Minuzzi L, Moreira PS, Morer A, Morgado P, Nakagawa A, Nakamae T, Nakao T, Narayanaswamy JC, Nurmi EL, O'Neill J, Pariente JC, Perriello C, Piacentini J, Piras F, Piras F, Pittenger C, Reddy YCJ, Rus-Oswald OG, Sakai Y, Sato JR, Schmaal L, Simpson HB, Soreni N, Soriano-Mas C, Spalletta G, Stern ER, Stevens MC, Stewart SE, Szeszko PR, Tolin DF, Tsuchiyagaito A, van Rooij D, van Wingen GA, Venkatasubramanian G, Wang Z, Yun JY; ENIGMA OCD Working Group, Thompson PM, Stein DJ, van den Heuvel OA, Francks C.

Biol Psychiatry. 2019 Apr 30. pii: S0006-3223(19)31292-2. doi: 10.1016/j.biopsych.2019.04.022. [Epub ahead of print]


New alumni EXperiences of Training and independent Unsupervised Practice (NEXT-UP): protocol for a cross-sectional study of early career general practitioners.

Magin P, Moad D, Tapley A, Holliday L, Davey A, Spike N, FitzGerald K, Kirby C, Bentley M, Turnock A, van Driel ML, Fielding A.

BMJ Open. 2019 May 30;9(5):e029585. doi: 10.1136/bmjopen-2019-029585.


Control of antiviral innate immune response by protein geranylgeranylation.

Yang S, Harding AT, Sweeney C, Miao D, Swan G, Zhou C, Jiang Z, Fitzgerald KA, Hammer G, Bergo MO, Kroh HK, Lacy DB, Sun C, Glogauer M, Que LG, Heaton NS, Wang D.

Sci Adv. 2019 May 29;5(5):eaav7999. doi: 10.1126/sciadv.aav7999. eCollection 2019 May.


HiChIRP reveals RNA-associated chromosome conformation.

Mumbach MR, Granja JM, Flynn RA, Roake CM, Satpathy AT, Rubin AJ, Qi Y, Jiang Z, Shams S, Louie BH, Guo JK, Gennert DG, Corces MR, Khavari PA, Atianand MK, Artandi SE, Fitzgerald KA, Greenleaf WJ, Chang HY.

Nat Methods. 2019 Jun;16(6):489-492. doi: 10.1038/s41592-019-0407-x. Epub 2019 May 27.


Measures of general and abdominal obesity and disability severity in a large population of people with multiple sclerosis.

Fitzgerald KC, Salter A, Tyry T, Fox RJ, Cutter G, Marrie RA.

Mult Scler. 2019 May 13:1352458519845836. doi: 10.1177/1352458519845836. [Epub ahead of print]


Cell Survival and Cytokine Release after Inflammasome Activation Is Regulated by the Toll-IL-1R Protein SARM.

Carty M, Kearney J, Shanahan KA, Hams E, Sugisawa R, Connolly D, Doran CG, Muñoz-Wolf N, Gürtler C, Fitzgerald KA, Lavelle EC, Fallon PG, Bowie AG.

Immunity. 2019 Jun 18;50(6):1412-1424.e6. doi: 10.1016/j.immuni.2019.04.005. Epub 2019 May 7.


Reduced Reward Responsiveness Predicts Change in Depressive Symptoms in Anxious Children and Adolescents Following Treatment.

Kujawa A, Burkhouse KL, Karich SR, Fitzgerald KD, Monk CS, Phan KL.

J Child Adolesc Psychopharmacol. 2019 Jun;29(5):378-385. doi: 10.1089/cap.2018.0172. Epub 2019 May 7.


Systemic therapy for advanced cutaneous squamous cell carcinoma.

Fitzgerald K, Tsai KK.

Semin Cutan Med Surg. 2019 Mar 1;38(1):E67-E74. doi: 10.12788/j.sder.2019.010. Review.


Sterility of Ethyl Chloride Spray After Use in the Clinic.

Sandrowski K, Graham J, Knott S, Hickok N, Fitzgerald K, Beredjiklian PK, Rivlin M.

Hand (N Y). 2019 May 3:1558944719846573. doi: 10.1177/1558944719846573. [Epub ahead of print]


Giving Voice to Vulnerable Children: Machine Learning Analysis of Speech Detects Anxiety and Depression in Early Childhood.

McGinnis EW, Anderau SP, Hruschak J, Gurchiek RD, Lopez-Duran NL, Fitzgerald K, Rosenblum KL, Muzik M, McGinnis RS.

IEEE J Biomed Health Inform. 2019 Nov;23(6):2294-2301. doi: 10.1109/JBHI.2019.2913590. Epub 2019 Apr 26.


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