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Dominant Role for Regulatory T Cells in Protecting Females Against Pulmonary Hypertension.

Tamosiuniene R, Manouvakhova O, Mesange P, Saito T, Qian J, Sanyal M, Lin YC, Nguyen LP, Luria A, Tu AB, Sante JM, Rabinovitch M, Fitzgerald DJ, Graham BB, Habtezion A, Voelkel NF, Aurelian L, Nicolls MR.

Circ Res. 2018 Jun 8;122(12):1689-1702. doi: 10.1161/CIRCRESAHA.117.312058. Epub 2018 Mar 15.


Minimal residual hairy cell leukemia eradication with moxetumomab pasudotox: phase 1 results and long-term follow-up.

Kreitman RJ, Tallman MS, Robak T, Coutre S, Wilson WH, Stetler-Stevenson M, FitzGerald DJ, Santiago L, Gao G, Lanasa MC, Pastan I.

Blood. 2018 May 24;131(21):2331-2334. doi: 10.1182/blood-2017-09-803072. Epub 2018 Feb 27.


Genetic variants in PPARGC1B and CNTN4 are associated with thromboxane A2 formation and with cardiovascular event free survival in the Anglo-Scandinavian Cardiac Outcomes Trial (ASCOT).

McCarthy NS, Vangjeli C, Surendran P, Treumann A, Rooney C, Ho E, Sever P, Thom S, Hughes AD, Munroe PB, Howard P, Johnson T, Caulfield M, Shields DC, O'Brien E, Fitzgerald DJ, Stanton AV.

Atherosclerosis. 2018 Feb;269:42-49. doi: 10.1016/j.atherosclerosis.2017.12.013. Epub 2017 Dec 8.


Lack of Bioequivalence Among Low-dose, Enteric-coated Aspirin Preparations.

Cox D, Fitzgerald DJ.

Clin Pharmacol Ther. 2018 Jun;103(6):1047-1051. doi: 10.1002/cpt.874. Epub 2017 Oct 25.


Analgesia by Deletion of Spinal Neurokinin 1 Receptor Expressing Neurons Using a Bioengineered Substance P-Pseudomonas Exotoxin Conjugate.

Iadarola MJ, Sapio MR, Wang X, Carrero H, Virata-Theimer ML, Sarnovsky R, Mannes AJ, FitzGerald DJ.

Mol Pain. 2017 Jan-Dec;13:1744806917727657. doi: 10.1177/1744806917727657.


Essential role for Bim in mediating the apoptotic and antitumor activities of immunotoxins.

Antignani A, Segal D, Simon N, Kreitman RJ, Huang D, FitzGerald DJ.

Oncogene. 2017 Aug 31;36(35):4953-4962. doi: 10.1038/onc.2017.111. Epub 2017 Apr 24.


Cadexomer iodine provides superior efficacy against bacterial wound biofilms in vitro and in vivo.

Fitzgerald DJ, Renick PJ, Forrest EC, Tetens SP, Earnest DN, McMillan J, Kiedaisch BM, Shi L, Roche ED.

Wound Repair Regen. 2017 Jan;25(1):13-24. doi: 10.1111/wrr.12497. Epub 2016 Dec 5.


An integrated design and fabrication strategy for entirely soft, autonomous robots.

Wehner M, Truby RL, Fitzgerald DJ, Mosadegh B, Whitesides GM, Lewis JA, Wood RJ.

Nature. 2016 Aug 25;536(7617):451-5. doi: 10.1038/nature19100.


Chemical Screens Identify Drugs that Enhance or Mitigate Cellular Responses to Antibody-Toxin Fusion Proteins.

Antignani A, Mathews Griner L, Guha R, Simon N, Pasetto M, Keller J, Huang M, Angelus E, Pastan I, Ferrer M, FitzGerald DJ, Thomas CJ.

PLoS One. 2016 Aug 24;11(8):e0161415. doi: 10.1371/journal.pone.0161415. eCollection 2016.


Milk-derived bioactive peptides and their health promoting effects: a potential role in atherosclerosis.

Marcone S, Belton O, Fitzgerald DJ.

Br J Clin Pharmacol. 2017 Jan;83(1):152-162. doi: 10.1111/bcp.13002. Epub 2016 Jun 17. Review.


Anticancer Effects of Mesothelin-Targeted Immunotoxin Therapy Are Regulated by Tyrosine Kinase DDR1.

Ali-Rahmani F, FitzGerald DJ, Martin S, Patel P, Prunotto M, Ormanoglu P, Thomas C, Pastan I.

Cancer Res. 2016 Mar 15;76(6):1560-8. doi: 10.1158/0008-5472.CAN-15-2401. Epub 2015 Dec 30.


Report from AmSECT's International Consortium for Evidence- Based Perfusion Consensus Statement: Minimal Criteria for Reporting Cardiopulmonary Bypass-Related Contributions to Red Blood Cell Transfusions Associated With Adult Cardiac Surgery.

Likosky DS, Baker RA, Dickinson TA, FitzGerald DJ, De Somer MF, Groom RC, FitzGerald D, Shann KG, Poullis M, Spiess BD, Jabr K, Lucas MT, Ferguson JD, Bronson SL.

J Extra Corpor Technol. 2015 Jun;47(2):83-9. Erratum in: J Extra Corpor Technol. 2015 Dec;47(4):251.


Proteomic signatures of antiplatelet drugs: new approaches to exploring drug effects.

Marcone S, Dervin F, Fitzgerald DJ.

J Thromb Haemost. 2015 Jun;13 Suppl 1:S323-31. doi: 10.1111/jth.12943. Review.


Whole-genome RNAi screen highlights components of the endoplasmic reticulum/Golgi as a source of resistance to immunotoxin-mediated cytotoxicity.

Pasetto M, Antignani A, Ormanoglu P, Buehler E, Guha R, Pastan I, Martin SE, FitzGerald DJ.

Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1135-42. doi: 10.1073/pnas.1501958112. Epub 2015 Feb 23.


Milk-derived bioactive peptides inhibit human endothelial-monocyte interactions via PPAR-γ dependent regulation of NF-κB.

Marcone S, Haughton K, Simpson PJ, Belton O, Fitzgerald DJ.

J Inflamm (Lond). 2015 Jan 20;12(1):1. doi: 10.1186/s12950-014-0044-1. eCollection 2015.


Blood volumes in cardiac surgery with cardiopulmonary bypass.

Hilberath JN, Smith T, Jara C, Thomas M, FitzGerald DJ, Muehlschlegel JD.

Perfusion. 2015 Jul;30(5):395-9. doi: 10.1177/0267659114550230. Epub 2014 Sep 23.


Blood volume measurement by hemodilution: association with valve disease and re-evaluation of the Allen Formula.

Hilberath JN, Thomas ME, Smith T, Jara C, Fitzgerald DJ, Wilusz K, Liu X, Muehlschlegel JD.

Perfusion. 2015 May;30(4):305-11. doi: 10.1177/0267659114547250. Epub 2014 Aug 14.


Targeted diphtheria toxin to treat BPDCN.

FitzGerald DJ.

Blood. 2014 Jul 17;124(3):310-2. doi: 10.1182/blood-2014-06-578633.


Tofacitinib suppresses antibody responses to protein therapeutics in murine hosts.

Onda M, Ghoreschi K, Steward-Tharp S, Thomas C, O'Shea JJ, Pastan IH, FitzGerald DJ.

J Immunol. 2014 Jul 1;193(1):48-55. doi: 10.4049/jimmunol.1400063. Epub 2014 Jun 2.


The medical decision model and decision maker tools for management of radiological and nuclear incidents.

Koerner JF, Coleman CN, Murrain-Hill P, FitzGerald DJ, Sullivan JM.

Health Phys. 2014 Jun;106(6):645-51. doi: 10.1097/HP.0000000000000053.


ABT-737 promotes the dislocation of ER luminal proteins to the cytosol, including pseudomonas exotoxin.

Antignani A, Sarnovsky R, FitzGerald DJ.

Mol Cancer Ther. 2014 Jun;13(6):1655-63. doi: 10.1158/1535-7163.MCT-13-0998. Epub 2014 Apr 16.


The interpretability of doctor identification badges in UK hospitals: a survey of nurses and patients.

Hickerton BC, Fitzgerald DJ, Perry E, De Bolla AR.

BMJ Qual Saf. 2014 Jul;23(7):543-7. doi: 10.1136/bmjqs-2013-002445. Epub 2014 Mar 5.


Immunotoxins for leukemia.

Wayne AS, Fitzgerald DJ, Kreitman RJ, Pastan I.

Blood. 2014 Apr 17;123(16):2470-7. doi: 10.1182/blood-2014-01-492256. Epub 2014 Feb 27. Review.


Combining the antimesothelin immunotoxin SS1P with the BH3-mimetic ABT-737 induces cell death in SS1P-resistant pancreatic cancer cells.

Hollevoet K, Antignani A, Fitzgerald DJ, Pastan I.

J Immunother. 2014 Jan;37(1):8-15. doi: 10.1097/CJI.0000000000000010.


Antitumor effects of immunotoxins are enhanced by lowering HCK or treatment with SRC kinase inhibitors.

Liu XF, Xiang L, FitzGerald DJ, Pastan I.

Mol Cancer Ther. 2014 Jan;13(1):82-9. doi: 10.1158/1535-7163.MCT-13-0726. Epub 2013 Oct 21.


Macrophage PPAR gamma Co-activator-1 alpha participates in repressing foam cell formation and atherosclerosis in response to conjugated linoleic acid.

McCarthy C, Lieggi NT, Barry D, Mooney D, de Gaetano M, James WG, McClelland S, Barry MC, Escoubet-Lozach L, Li AC, Glass CK, Fitzgerald DJ, Belton O.

EMBO Mol Med. 2013 Sep;5(9):1443-57. doi: 10.1002/emmm.201302587. Epub 2013 Aug 21.


Proteomic identification of the candidate target proteins of 15-deoxy-delta12,14-prostaglandin J2.

Marcone S, Fitzgerald DJ.

Proteomics. 2013 Jul;13(14):2135-9. doi: 10.1002/pmic.201200289.


The insulin receptor negatively regulates the action of Pseudomonas toxin-based immunotoxins and native Pseudomonas toxin.

Liu XF, FitzGerald DJ, Pastan I.

Cancer Res. 2013 Apr 1;73(7):2281-8. doi: 10.1158/0008-5472.CAN-12-3436. Epub 2013 Jan 24.


Gene gymnastics: Synthetic biology for baculovirus expression vector system engineering.

Vijayachandran LS, Thimiri Govinda Raj DB, Edelweiss E, Gupta K, Maier J, Gordeliy V, Fitzgerald DJ, Berger I.

Bioengineered. 2013 Sep-Oct;4(5):279-87. doi: 10.4161/bioe.22966. Epub 2013 Jan 17.


Historical lessons in translational medicine: cyclooxygenase inhibition and P2Y12 antagonism.

Fitzgerald DJ, Fitzgerald GA.

Circ Res. 2013 Jan 4;112(1):174-94. doi: 10.1161/CIRCRESAHA.111.300271.


Anti-CD22-chimeric antigen receptors targeting B-cell precursor acute lymphoblastic leukemia.

Haso W, Lee DW, Shah NN, Stetler-Stevenson M, Yuan CM, Pastan IH, Dimitrov DS, Morgan RA, FitzGerald DJ, Barrett DM, Wayne AS, Mackall CL, Orentas RJ.

Blood. 2013 Feb 14;121(7):1165-74. doi: 10.1182/blood-2012-06-438002. Epub 2012 Dec 14.


Canonical Wnt signaling in megakaryocytes regulates proplatelet formation.

Macaulay IC, Thon JN, Tijssen MR, Steele BM, MacDonald BT, Meade G, Burns P, Rendon A, Salunkhe V, Murphy RP, Bennett C, Watkins NA, He X, Fitzgerald DJ, Italiano JE Jr, Maguire PB.

Blood. 2013 Jan 3;121(1):188-96. doi: 10.1182/blood-2012-03-416875. Epub 2012 Nov 16.


IL-10 mediates the immunoregulatory response in conjugated linoleic acid-induced regression of atherosclerosis.

McCarthy C, Duffy MM, Mooney D, James WG, Griffin MD, Fitzgerald DJ, Belton O.

FASEB J. 2013 Feb;27(2):499-510. doi: 10.1096/fj.12-215442. Epub 2012 Oct 15.


Combination treatments with ABT-263 and an immunotoxin produce synergistic killing of ABT-263-resistant small cell lung cancer cell lines.

Mattoo AR, FitzGerald DJ.

Int J Cancer. 2013 Feb 15;132(4):978-87. doi: 10.1002/ijc.27732. Epub 2012 Aug 16.


WNT-3a modulates platelet function by regulating small GTPase activity.

Steele BM, Harper MT, Smolenski AP, Alkazemi N, Poole AW, Fitzgerald DJ, Maguire PB.

FEBS Lett. 2012 Jul 30;586(16):2267-72. doi: 10.1016/j.febslet.2012.05.060. Epub 2012 Jun 13.


Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy.

Wei H, Xiang L, Wayne AS, Chertov O, FitzGerald DJ, Bera TK, Pastan I.

Proc Natl Acad Sci U S A. 2012 May 1;109(18):6898-903. doi: 10.1073/pnas.1204523109. Epub 2012 Apr 16.


Phase I trial of anti-CD22 recombinant immunotoxin moxetumomab pasudotox (CAT-8015 or HA22) in patients with hairy cell leukemia.

Kreitman RJ, Tallman MS, Robak T, Coutre S, Wilson WH, Stetler-Stevenson M, Fitzgerald DJ, Lechleider R, Pastan I.

J Clin Oncol. 2012 May 20;30(15):1822-8. doi: 10.1200/JCO.2011.38.1756. Epub 2012 Feb 21.


Commentary on: case report: The use of zero-balance ultrafiltration to correct acute metabolic acidosis after prolonged hypothermic circulatory arrest.

Fitzgerald DJ.

Perfusion. 2012 Jan;27(1):12. doi: 10.1177/0267659111412004. No abstract available.


Treatment of hematologic malignancies with immunotoxins and antibody-drug conjugates.

FitzGerald DJ, Wayne AS, Kreitman RJ, Pastan I.

Cancer Res. 2011 Oct 15;71(20):6300-9. doi: 10.1158/0008-5472.CAN-11-1374. Review.


Aeromedical decision making in attention-deficit/hyperactivity disorder.

Fitzgerald DJ, Navathe PD, Drane AM.

Aviat Space Environ Med. 2011 May;82(5):550-4. Review.


Recombinant immunotoxins and other therapies for relapsed/refractory hairy cell leukemia.

Kreitman RJ, Arons E, Stetler-Stevenson M, Fitzgerald DJ, Wilson WH, Pastan I.

Leuk Lymphoma. 2011 Jun;52 Suppl 2:82-6. doi: 10.3109/10428194.2011.565843. Review.


Enhancing immunotoxin cell-killing activity via combination therapy with ABT-737.

Fitzgerald DJ, Moskatel E, Ben-Josef G, Traini R, Tendler T, Sharma A, Antignani A, Mussai F, Wayne A, Kreitman RJ, Pastan I.

Leuk Lymphoma. 2011 Jun;52 Suppl 2:79-81. doi: 10.3109/10428194.2011.569961. Review.


Structure and mechanism of the chromatin remodelling factor ISW1a.

Yamada K, Frouws TD, Angst B, Fitzgerald DJ, DeLuca C, Schimmele K, Sargent DF, Richmond TJ.

Nature. 2011 Apr 28;472(7344):448-53. doi: 10.1038/nature09947.


Safety and tolerability of atopaxar in the treatment of patients with acute coronary syndromes: the lessons from antagonizing the cellular effects of Thrombin–Acute Coronary Syndromes Trial.

O'Donoghue ML, Bhatt DL, Wiviott SD, Goodman SG, Fitzgerald DJ, Angiolillo DJ, Goto S, Montalescot G, Zeymer U, Aylward PE, Guetta V, Dudek D, Ziecina R, Contant CF, Flather MD; LANCELOT-ACS Investigators.

Circulation. 2011 May 3;123(17):1843-53. doi: 10.1161/CIRCULATIONAHA.110.000786. Epub 2011 Apr 18.


Randomized trial of atopaxar in the treatment of patients with coronary artery disease: the lessons from antagonizing the cellular effect of Thrombin–Coronary Artery Disease Trial.

Wiviott SD, Flather MD, O'Donoghue ML, Goto S, Fitzgerald DJ, Cura F, Aylward P, Guetta V, Dudek D, Contant CF, Angiolillo DJ, Bhatt DL; LANCELOT-CAD Investigators.

Circulation. 2011 May 3;123(17):1854-63. doi: 10.1161/CIRCULATIONAHA.110.001404. Epub 2011 Apr 18.


2011 update to the Society of Thoracic Surgeons and the Society of Cardiovascular Anesthesiologists blood conservation clinical practice guidelines.

Society of Thoracic Surgeons Blood Conservation Guideline Task Force, Ferraris VA, Brown JR, Despotis GJ, Hammon JW, Reece TB, Saha SP, Song HK, Clough ER; Society of Cardiovascular Anesthesiologists Special Task Force on Blood Transfusion, Shore-Lesserson LJ, Goodnough LT, Mazer CD, Shander A, Stafford-Smith M, Waters J; International Consortium for Evidence Based Perfusion, Baker RA, Dickinson TA, FitzGerald DJ, Likosky DS, Shann KG.

Ann Thorac Surg. 2011 Mar;91(3):944-82. doi: 10.1016/j.athoracsur.2010.11.078. Review.


SorLA modulates atheroprotective properties of CLA by regulating monocyte migration.

McCarthy C, O'Gaora P, James WG, de Gaetano M, McClelland S, Fitzgerald DJ, Belton O.

Atherosclerosis. 2010 Dec;213(2):400-7. doi: 10.1016/j.atherosclerosis.2010.09.025. Epub 2010 Oct 20. Erratum in: Atherosclerosis. 2011 May;216(1):250.


Insulin-dependent diabetes and aeromedical certification - the Australian perspective.

Fitzgerald DJ, Navathe PD, Drane AM.

Med J Aust. 2010 Oct 18;193(8):469-71.


Transcription profiling in human platelets reveals LRRFIP1 as a novel protein regulating platelet function.

Goodall AH, Burns P, Salles I, Macaulay IC, Jones CI, Ardissino D, de Bono B, Bray SL, Deckmyn H, Dudbridge F, Fitzgerald DJ, Garner SF, Gusnanto A, Koch K, Langford C, O'Connor MN, Rice CM, Stemple D, Stephens J, Trip MD, Zwaginga JJ, Samani NJ, Watkins NA, Maguire PB, Ouwehand WH; Bloodomics Consortium.

Blood. 2010 Nov 25;116(22):4646-56. doi: 10.1182/blood-2010-04-280925. Epub 2010 Sep 10.

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