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A protocol for a systematic review of process evaluations of interventions investigating sedentary behaviour in adults.

Corepal R, Hall JF, English C, Farrin A, Fitzsimons CF, Forster A, Lawton R, Mead G, Clarke D.

BMJ Open. 2019 Sep 18;9(9):e031291. doi: 10.1136/bmjopen-2019-031291.


Exploring adults' experiences of sedentary behaviour and participation in non-workplace interventions designed to reduce sedentary behaviour: a thematic synthesis of qualitative studies.

Rawlings GH, Williams RK, Clarke DJ, English C, Fitzsimons C, Holloway I, Lawton R, Mead G, Patel A, Forster A.

BMC Public Health. 2019 Aug 13;19(1):1099. doi: 10.1186/s12889-019-7365-1.


The effect of breed and diet type on the global transcriptome of hepatic tissue in beef cattle divergent for feed efficiency.

Higgins MG, Kenny DA, Fitzsimons C, Blackshields G, Coyle S, McKenna C, McGee M, Morris DW, Waters SM.

BMC Genomics. 2019 Jun 26;20(1):525. doi: 10.1186/s12864-019-5906-8.


Circadian glucocorticoid oscillations preserve a population of adult hippocampal neural stem cells in the aging brain.

Schouten M, Bielefeld P, Garcia-Corzo L, Passchier EMJ, Gradari S, Jungenitz T, Pons-Espinal M, Gebara E, Martín-Suárez S, Lucassen PJ, De Vries HE, Trejo JL, Schwarzacher SW, De Pietri Tonelli D, Toni N, Mira H, Encinas JM, Fitzsimons CP.

Mol Psychiatry. 2019 Jun 20. doi: 10.1038/s41380-019-0440-2. [Epub ahead of print]


Insult-induced aberrant hippocampal neurogenesis: Functional consequences and possible therapeutic strategies.

Bielefeld P, Durá I, Danielewicz J, Lucassen PJ, Baekelandt V, Abrous DN, Encinas JM, Fitzsimons CP.

Behav Brain Res. 2019 Oct 17;372:112032. doi: 10.1016/j.bbr.2019.112032. Epub 2019 Jun 12. Review.


The effects of yoga compared to active and inactive controls on physical function and health related quality of life in older adults- systematic review and meta-analysis of randomised controlled trials.

Sivaramakrishnan D, Fitzsimons C, Kelly P, Ludwig K, Mutrie N, Saunders DH, Baker G.

Int J Behav Nutr Phys Act. 2019 Apr 5;16(1):33. doi: 10.1186/s12966-019-0789-2.


A Model of Glucocorticoid Receptor Interaction With Coregulators Predicts Transcriptional Regulation of Target Genes.

Monczor F, Chatzopoulou A, Zappia CD, Houtman R, Meijer OC, Fitzsimons CP.

Front Pharmacol. 2019 Mar 13;10:214. doi: 10.3389/fphar.2019.00214. eCollection 2019.


Co-administration of Anti microRNA-124 and -137 Oligonucleotides Prevents Hippocampal Neural Stem Cell Loss Upon Non-convulsive Seizures.

Bielefeld P, Schouten M, Meijer GM, Breuk MJ, Geijtenbeek K, Karayel S, Tiaglik A, Vuuregge AH, Willems RAL, Witkamp D, Lucassen PJ, Encinas JM, Fitzsimons CP.

Front Mol Neurosci. 2019 Feb 19;12:31. doi: 10.3389/fnmol.2019.00031. eCollection 2019.


GWAS and eQTL analysis identifies a SNP associated with both residual feed intake and GFRA2 expression in beef cattle.

Higgins MG, Fitzsimons C, McClure MC, McKenna C, Conroy S, Kenny DA, McGee M, Waters SM, Morris DW.

Sci Rep. 2018 Sep 24;8(1):14301. doi: 10.1038/s41598-018-32374-6.


Characteristics of a protocol to collect objective physical activity/sedentary behaviour data in a large study: Seniors USP (understanding sedentary patterns).

Dall PM, Skelton DA, Dontje ML, Coulter EH, Stewart S, Cox SR, Shaw RJ, Čukić I, Fitzsimons CF, Greig CA, Granat MH, Der G, Deary IJ, Chastin S.

J Meas Phys Behav. 2018 Mar;1(1):26-31. doi: 10.1123/jmpb.2017-0004.


16S rRNA Sequencing Reveals Relationship Between Potent Cellulolytic Genera and Feed Efficiency in the Rumen of Bulls.

McGovern E, Kenny DA, McCabe MS, Fitzsimons C, McGee M, Kelly AK, Waters SM.

Front Microbiol. 2018 Aug 10;9:1842. doi: 10.3389/fmicb.2018.01842. eCollection 2018.


A population survey of prevalence rates of antenatal depression in the Irish obstetric services using the Edinburgh Postnatal Depression Scale (EPDS).

Jairaj C, Fitzsimons CM, McAuliffe FM, O'Leary N, Joyce N, McCarthy A, Cassidy E, Donnelly J, Tully E, Imcha M, Austin J, Doolin K, Farrell C, O'Keane V.

Arch Womens Ment Health. 2019 Jun;22(3):349-355. doi: 10.1007/s00737-018-0893-3. Epub 2018 Aug 1.


Sedentary behavior after stroke: A new target for therapeutic intervention.

Morton S, Fitzsimons C, Hall J, Clarke D, Forster A, English C, Chastin S, Birch KM, Mead G.

Int J Stroke. 2019 Jan;14(1):9-11. doi: 10.1177/1747493018784505. Epub 2018 Jul 4.


Glucocorticoid-mediated modulation of morphological changes associated with aging in microglia.

van Olst L, Bielefeld P, Fitzsimons CP, de Vries HE, Schouten M.

Aging Cell. 2018 Aug;17(4):e12790. doi: 10.1111/acel.12790. Epub 2018 Jun 7.


Invited review: Improving feed efficiency of beef cattle - the current state of the art and future challenges.

Kenny DA, Fitzsimons C, Waters SM, McGee M.

Animal. 2018 Sep;12(9):1815-1826. doi: 10.1017/S1751731118000976. Epub 2018 May 21. Review.


What Do Older People Do When Sitting and Why? Implications for Decreasing Sedentary Behavior.

Palmer VJ, Gray CM, Fitzsimons CF, Mutrie N, Wyke S, Deary IJ, Der G, Chastin SFM, Skelton DA; Seniors USP Team.

Gerontologist. 2019 Jul 16;59(4):686-697. doi: 10.1093/geront/gny020.


miRNA-Mediated Regulation of Adult Hippocampal Neurogenesis; Implications for Epilepsy.

Bielefeld P, Mooney C, Henshall DC, Fitzsimons CP.

Brain Plast. 2017 Nov 9;3(1):43-59. doi: 10.3233/BPL-160036. Review.


JAK/STAT inhibitors and other small molecule cytokine antagonists for the treatment of allergic disease.

Howell MD, Fitzsimons C, Smith PA.

Ann Allergy Asthma Immunol. 2018 Apr;120(4):367-375. doi: 10.1016/j.anai.2018.02.012. Epub 2018 Feb 14. Review.


Gene regulation in adult neural stem cells. Current challenges and possible applications.

Encinas JM, Fitzsimons CP.

Adv Drug Deliv Rev. 2017 Oct 1;120:118-132. doi: 10.1016/j.addr.2017.07.016. Epub 2017 Jul 25. Review.


Differences by age and sex in the sedentary time of adults in Scotland.

Strain T, Kelly P, Mutrie N, Fitzsimons C.

J Sports Sci. 2018 Apr;36(7):732-741. doi: 10.1080/02640414.2017.1339904. Epub 2017 Jun 16.


A Standardized Protocol for Stereotaxic Intrahippocampal Administration of Kainic Acid Combined with Electroencephalographic Seizure Monitoring in Mice.

Bielefeld P, Sierra A, Encinas JM, Maletic-Savatic M, Anderson A, Fitzsimons CP.

Front Neurosci. 2017 Mar 29;11:160. doi: 10.3389/fnins.2017.00160. eCollection 2017.


TAxonomy of Self-reported Sedentary behaviour Tools (TASST) framework for development, comparison and evaluation of self-report tools: content analysis and systematic review.

Dall PM, Coulter EH, Fitzsimons CF, Skelton DA, Chastin S; Seniors USP Team.

BMJ Open. 2017 Apr 8;7(4):e013844. doi: 10.1136/bmjopen-2016-013844. Review.


Transcription factor oscillations in neural stem cells: Implications for accurate control of gene expression.

Bielefeld P, Schouten M, Lucassen PJ, Fitzsimons CP.

Neurogenesis (Austin). 2017 Feb 10;4(1):e1262934. doi: 10.1080/23262133.2016.1262934. eCollection 2017. Review.


Configurations of the Re-scan Confocal Microscope (RCM) for biomedical applications.

DE Luca GMR, Desclos E, Breedijk RMP, Dolz-Edo L, Smits GJ, Nahidiazar L, Bielefeld P, Picavet L, Fitzsimons CP, Hoebe R, Manders EMM.

J Microsc. 2017 May;266(2):166-177. doi: 10.1111/jmi.12526. Epub 2017 Mar 3.


Multi-omics profile of the mouse dentate gyrus after kainic acid-induced status epilepticus.

Schouten M, Bielefeld P, Fratantoni SA, Hubens CJ, Piersma SR, Pham TV, Voskuyl RA, Lucassen PJ, Jimenez CR, Fitzsimons CP.

Sci Data. 2016 Aug 16;3:160068. doi: 10.1038/sdata.2016.68.


Circadian and ultradian glucocorticoid rhythmicity: Implications for the effects of glucocorticoids on neural stem cells and adult hippocampal neurogenesis.

Fitzsimons CP, Herbert J, Schouten M, Meijer OC, Lucassen PJ, Lightman S.

Front Neuroendocrinol. 2016 Apr;41:44-58. doi: 10.1016/j.yfrne.2016.05.001. Epub 2016 May 24. Review.


Should we reframe how we think about physical activity and sedentary behaviour measurement? Validity and reliability reconsidered.

Kelly P, Fitzsimons C, Baker G.

Int J Behav Nutr Phys Act. 2016 Mar 1;13:32. doi: 10.1186/s12966-016-0351-4.


Age-related comparisons by sex in the domains of aerobic physical activity for adults in Scotland.

Strain T, Fitzsimons C, Foster C, Mutrie N, Townsend N, Kelly P.

Prev Med Rep. 2015 Dec 30;3:90-7. doi: 10.1016/j.pmedr.2015.12.013. eCollection 2016 Jun.


Effects of histamine H1 receptor signaling on glucocorticoid receptor activity. Role of canonical and non-canonical pathways.

Zappia CD, Granja-Galeano G, Fernández N, Shayo C, Davio C, Fitzsimons CP, Monczor F.

Sci Rep. 2015 Dec 4;5:17476. doi: 10.1038/srep17476.


Regulation of Adult Neurogenesis and Plasticity by (Early) Stress, Glucocorticoids, and Inflammation.

Lucassen PJ, Oomen CA, Naninck EF, Fitzsimons CP, van Dam AM, Czeh B, Korosi A.

Cold Spring Harb Perspect Biol. 2015 Sep 1;7(9):a021303. doi: 10.1101/cshperspect.a021303. Review.


MicroRNA-124 and -137 cooperativity controls caspase-3 activity through BCL2L13 in hippocampal neural stem cells.

Schouten M, Fratantoni SA, Hubens CJ, Piersma SR, Pham TV, Bielefeld P, Voskuyl RA, Lucassen PJ, Jimenez CR, Fitzsimons CP.

Sci Rep. 2015 Jul 24;5:12448. doi: 10.1038/srep12448.


Interventions with potential to reduce sedentary time in adults: systematic review and meta-analysis.

Martin A, Fitzsimons C, Jepson R, Saunders DH, van der Ploeg HP, Teixeira PJ, Gray CM, Mutrie N; EuroFIT consortium.

Br J Sports Med. 2015 Aug;49(16):1056-63. doi: 10.1136/bjsports-2014-094524. Epub 2015 Apr 23. Review.


Environmental control of adult neurogenesis: from hippocampal homeostasis to behavior and disease.

Kuipers SD, Bramham CR, Cameron HA, Fitzsimons CP, Korosi A, Lucassen PJ.

Neural Plast. 2014;2014:808643. doi: 10.1155/2014/808643. Epub 2014 Dec 18. No abstract available.


Sedentary behavior in the first year after stroke: a longitudinal cohort study with objective measures.

Tieges Z, Mead G, Allerhand M, Duncan F, van Wijck F, Fitzsimons C, Greig C, Chastin S.

Arch Phys Med Rehabil. 2015 Jan;96(1):15-23. doi: 10.1016/j.apmr.2014.08.015. Epub 2014 Sep 16.


Effects of phenotypic residual feed intake on response to a glucose tolerance test and gene expression in the insulin signaling pathway in longissimus dorsi in beef cattle.

Fitzsimons C, Kenny DA, Waters SM, Earley B, McGee M.

J Anim Sci. 2014 Oct;92(10):4616-31. doi: 10.2527/jas.2014-7699. Epub 2014 Aug 1.


Proteinuria, (99m) Tc-DTPA Scintigraphy, Creatinine-, Cystatin- and Combined-Based Equations in the Assessment of Chronic Kidney Disease.

Trimarchi H, Muryan A, Toscano A, Martino D, Forrester M, Pomeranz V, Lombi F, Young P, Raña MS, Karl A, Alonso M, Dicugno M, Fitzsimons C.

ISRN Nephrol. 2014 Feb 11;2014:430247. doi: 10.1155/2014/430247. eCollection 2014.


Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease.

Fitzsimons CP, van Bodegraven E, Schouten M, Lardenoije R, Kompotis K, Kenis G, van den Hurk M, Boks MP, Biojone C, Joca S, Steinbusch HW, Lunnon K, Mastroeni DF, Mill J, Lucassen PJ, Coleman PD, van den Hove DL, Rutten BP.

Mol Neurodegener. 2014 Jun 25;9:25. doi: 10.1186/1750-1326-9-25. Review.


Imaging dendritic spines of rat primary hippocampal neurons using structured illumination microscopy.

Schouten M, De Luca GM, Alatriste González DK, de Jong BE, Timmermans W, Xiong H, Krugers H, Manders EM, Fitzsimons CP.

J Vis Exp. 2014 May 4;(87). doi: 10.3791/51276.


Visceral organ weights, digestion and carcass characteristics of beef bulls differing in residual feed intake offered a high concentrate diet.

Fitzsimons C, Kenny DA, McGee M.

Animal. 2014 Jun;8(6):949-59. doi: 10.1017/S1751731114000652. Epub 2014 Mar 28.


Feeding behavior, ruminal fermentation, and performance of pregnant beef cows differing in phenotypic residual feed intake offered grass silage.

Fitzsimons C, Kenny DA, Fahey AG, McGee M.

J Anim Sci. 2014 May;92(5):2170-81. doi: 10.2527/jas.2013-7438. Epub 2014 Mar 18.


Different subsets of newborn granule cells: a possible role in epileptogenesis?

Bielefeld P, van Vliet EA, Gorter JA, Lucassen PJ, Fitzsimons CP.

Eur J Neurosci. 2014 Jan;39(1):1-11. doi: 10.1111/ejn.12387. Epub 2013 Oct 16. Review.


Epigenetically regulated microRNAs in Alzheimer's disease.

Van den Hove DL, Kompotis K, Lardenoije R, Kenis G, Mill J, Steinbusch HW, Lesch KP, Fitzsimons CP, De Strooper B, Rutten BP.

Neurobiol Aging. 2014 Apr;35(4):731-45. doi: 10.1016/j.neurobiolaging.2013.10.082. Epub 2013 Oct 18. Review.


Methane emissions, body composition, and rumen fermentation traits of beef heifers differing in residual feed intake.

Fitzsimons C, Kenny DA, Deighton MH, Fahey AG, McGee M.

J Anim Sci. 2013 Dec;91(12):5789-800. doi: 10.2527/jas.2013-6956. Epub 2013 Oct 21.


Silencing of doublecortin-like (DCL) results in decreased mitochondrial activity and delayed neuroblastoma tumor growth.

Verissimo CS, Elands R, Cheng S, Saaltink DJ, ter Horst JP, Alme MN, Pont C, van de Water B, Håvik B, Fitzsimons CP, Vreugdenhil E.

PLoS One. 2013 Sep 26;8(9):e75752. doi: 10.1371/journal.pone.0075752. eCollection 2013.


Perinatal programming of adult hippocampal structure and function; emerging roles of stress, nutrition and epigenetics.

Lucassen PJ, Naninck EF, van Goudoever JB, Fitzsimons C, Joels M, Korosi A.

Trends Neurosci. 2013 Nov;36(11):621-31. doi: 10.1016/j.tins.2013.08.002. Epub 2013 Aug 30.


Using an individualised consultation and activPAL™ feedback to reduce sedentary time in older Scottish adults: results of a feasibility and pilot study.

Fitzsimons CF, Kirk A, Baker G, Michie F, Kane C, Mutrie N.

Prev Med. 2013 Nov;57(5):718-20. doi: 10.1016/j.ypmed.2013.07.017. Epub 2013 Jul 25.


Antihistaminergics and inverse agonism: potential therapeutic applications.

Monczor F, Fernandez N, Fitzsimons CP, Shayo C, Davio C.

Eur J Pharmacol. 2013 Sep 5;715(1-3):26-32. doi: 10.1016/j.ejphar.2013.06.027. Epub 2013 Jul 4. Review.


microRNAs and the regulation of neuronal plasticity under stress conditions.

Schouten M, Aschrafi A, Bielefeld P, Doxakis E, Fitzsimons CP.

Neuroscience. 2013 Jun 25;241:188-205. doi: 10.1016/j.neuroscience.2013.02.065. Epub 2013 Mar 13. Review.


Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior.

Fitzsimons CP, van Hooijdonk LW, Schouten M, Zalachoras I, Brinks V, Zheng T, Schouten TG, Saaltink DJ, Dijkmans T, Steindler DA, Verhaagen J, Verbeek FJ, Lucassen PJ, de Kloet ER, Meijer OC, Karst H, Joels M, Oitzl MS, Vreugdenhil E.

Mol Psychiatry. 2013 Sep;18(9):993-1005. doi: 10.1038/mp.2012.123. Epub 2012 Aug 28.


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