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Cost-effectiveness of implementing objective diagnostic verification of asthma in the United States.

Yaghoubi M, Adibi A, Zafari Z, FitzGerald JM, Aaron SD, Johnson KM, Sadatsafavi M.

J Allergy Clin Immunol. 2019 Dec 11. pii: S0091-6749(19)31634-3. doi: 10.1016/j.jaci.2019.11.038. [Epub ahead of print]


Cholinergic synapse pathway gene polymorphisms associated with allergen-induced late asthmatic responses.

Rajasekaran A, He D, Yue A, Singh A, Shannon CP, FitzGerald JM, Boulet LP, O'Byrne PM, Gauvreau GM, Tebbutt SJ.

ERJ Open Res. 2019 Nov 4;5(4). pii: 00107-2019. doi: 10.1183/23120541.00107-2019. eCollection 2019 Oct.


Direct costs of overdiagnosed asthma: a longitudinal, population-based cohort study in British Columbia, Canada.

Ng B, Sadatsafavi M, Safari A, FitzGerald JM, Johnson KM.

BMJ Open. 2019 Nov 7;9(11):e031306. doi: 10.1136/bmjopen-2019-031306.


Reslizumab and mepolizumab for moderate-to-severe poorly controlled asthma: an indirect comparison meta-analysis.

Yan K, Balijepalli C, Sharma R, Barakat S, Sun SX, Falcao S, Druyts E, FitzGerald JM.

Immunotherapy. 2019 Dec;11(17):1491-1505. doi: 10.2217/imt-2019-0113. Epub 2019 Nov 5.


Tiotropium add-on therapy reduces seasonal peaks of asthma worsening in adults with symptomatic severe asthma.

FitzGerald JM, Buhl R, Casale TB, Jugovic B, Zaremba-Pechmann L, Halpin DMG.

Eur Respir J. 2019 Oct 16. pii: 1900964. doi: 10.1183/13993003.00964-2019. [Epub ahead of print] No abstract available.


Triple therapy in a single inhaler: a new option for uncontrolled asthma.

FitzGerald JM, Sadatsafavi M.

Lancet. 2019 Nov 9;394(10210):1690-1692. doi: 10.1016/S0140-6736(19)32216-0. Epub 2019 Sep 30. No abstract available.


Trends in prescriptions and costs of inhaled medications in chronic obstructive pulmonary disease: a 19-year population-based study from Canada.

Tavakoli H, Johnson KM, FitzGerald JM, Sin DD, Gershon AS, Kendzerska T, Sadatsafavi M.

Int J Chron Obstruct Pulmon Dis. 2019 Sep 3;14:2003-2013. doi: 10.2147/COPD.S210897. eCollection 2019.


An Individualized Prediction Model for Long-term Lung Function Trajectory and Risk of COPD in the General Population.

Chen W, Sin DD, FitzGerald JM, Safari A, Adibi A, Sadatsafavi M.

Chest. 2019 Sep 19. pii: S0012-3692(19)33868-1. doi: 10.1016/j.chest.2019.09.003. [Epub ahead of print]


The effects of marijuana smoking on lung function in older people.

Tan WC, Bourbeau J, Aaron SD, Hogg JC, Maltais F, Hernandez P, Marciniuk DD, Chapman KR, To T, FitzGerald JM, Walker BL, Road J, Zheng L, Zhou G, Yau T, Benedetti A, O'Donnell D, Sin DD; CanCOLD Collaborative Research Group.

Eur Respir J. 2019 Sep 19. pii: 1900826. doi: 10.1183/13993003.00826-2019. [Epub ahead of print]


Economic burden of multimorbidity in patients with severe asthma: a 20-year population-based study.

Chen W, Safari A, FitzGerald JM, Sin DD, Tavakoli H, Sadatsafavi M.

Thorax. 2019 Dec;74(12):1113-1119. doi: 10.1136/thoraxjnl-2019-213223. Epub 2019 Sep 18.


A Systematic Review of Decision-Analytic Models for Evaluating Cost-Effectiveness of Asthma Interventions.

Ehteshami-Afshar S, Zafari Z, Hamidi N, FitzGerald JM, Lynd L, Sadatsafavi M.

Value Health. 2019 Sep;22(9):1070-1082. doi: 10.1016/j.jval.2019.03.016. Epub 2019 May 23. Review.


Long-term Safety and Clinical Benefit of Mepolizumab in Patients With the Most Severe Eosinophilic Asthma: The COSMEX Study.

Khurana S, Brusselle GG, Bel EH, FitzGerald JM, Masoli M, Korn S, Kato M, Albers FC, Bradford ES, Gilson MJ, Price RG, Humbert M.

Clin Ther. 2019 Oct;41(10):2041-2056.e5. doi: 10.1016/j.clinthera.2019.07.007. Epub 2019 Aug 22.


Effect of short-term oral prednisone therapy on blood gene expression: a randomised controlled clinical trial.

Takiguchi H, Chen V, Obeidat M, Hollander Z, FitzGerald JM, McManus BM, Ng RT, Sin DD.

Respir Res. 2019 Aug 5;20(1):176. doi: 10.1186/s12931-019-1147-2.


Asthma impacts on workplace productivity in employed patients who are symptomatic despite background therapy: a multinational survey.

Gruffydd-Jones K, Thomas M, Roman-Rodríguez M, Infantino A, FitzGerald JM, Pavord I, Haddon JM, Elsasser U, Vogelberg C.

J Asthma Allergy. 2019 Jul 11;12:183-194. doi: 10.2147/JAA.S204278. eCollection 2019.


Peak expiratory flow as an endpoint for clinical trials in asthma: a comparison with FEV1.

Halpin DMG, Meltzer EO, Pisternick-Ruf W, Moroni-Zentgraf P, Engel M, Zaremba-Pechmann L, Casale T, FitzGerald JM.

Respir Res. 2019 Jul 18;20(1):159. doi: 10.1186/s12931-019-1119-6.


Patient and Professional Perspectives on Nutrition in Chronic Respiratory Disease Self-Management: Reflections on Nutrition and Food Literacies.

Hakami R, Gillis DE, Poureslami I, FitzGerald JM.

Health Lit Res Pract. 2018 Sep 13;2(3):e166-e174. doi: 10.3928/24748307-20180803-01. eCollection 2018 Jul.


The Global Initiative for Asthma (GINA): 25 years later.

Boulet LP, Reddel HK, Bateman E, Pedersen S, FitzGerald JM, O'Byrne PM.

Eur Respir J. 2019 Aug 29;54(2). pii: 1900598. doi: 10.1183/13993003.00598-2019. Print 2019 Aug. Review.


GINA 2019: a fundamental change in asthma management: Treatment of asthma with short-acting bronchodilators alone is no longer recommended for adults and adolescents.

Reddel HK, FitzGerald JM, Bateman ED, Bacharier LB, Becker A, Brusselle G, Buhl R, Cruz AA, Fleming L, Inoue H, Ko FW, Krishnan JA, Levy ML, Lin J, Pedersen SE, Sheikh A, Yorgancioglu A, Boulet LP.

Eur Respir J. 2019 Jun 27;53(6). pii: 1901046. doi: 10.1183/13993003.01046-2019. Print 2019 Jun. No abstract available.


The Projected Economic and Health Burden of Uncontrolled Asthma in the United States.

Yaghoubi M, Adibi A, Safari A, FitzGerald JM, Sadatsafavi M.

Am J Respir Crit Care Med. 2019 Nov 1;200(9):1102-1112. doi: 10.1164/rccm.201901-0016OC.


The Challenges and Opportunities of Maximizing the Benefits of Severe Asthma Registries.

FitzGerald JM, Alramezi Y.

J Allergy Clin Immunol Pract. 2019 May - Jun;7(5):1469-1470. doi: 10.1016/j.jaip.2018.11.053. No abstract available.


Inhaled corticosteroids and the risk of lung cancer in COPD: a population-based cohort study.

Raymakers AJN, Sadatsafavi M, Sin DD, FitzGerald JM, Marra CA, Lynd LD.

Eur Respir J. 2019 Jun 5;53(6). pii: 1801257. doi: 10.1183/13993003.01257-2018. Print 2019 Jun.


Diagnosis and management of asthma, COPD and asthma-COPD overlap among primary care physicians and respiratory/allergy specialists: A global survey.

Jenkins C, FitzGerald JM, Martinez FJ, Postma DS, Rennard S, van der Molen T, Gardev A, Genofre E, Calverley P.

Clin Respir J. 2019 Jun;13(6):355-367. doi: 10.1111/crj.13016. Epub 2019 Mar 24.


Extent, trends, and determinants of controller/reliever balance in mild asthma: a 14-year population-based study.

Khakban A, FitzGerald JM, Tavakoli H, Lynd L, Ehteshami-Afshar S, Sadatsafavi M.

Respir Res. 2019 Feb 28;20(1):44. doi: 10.1186/s12931-019-1007-0.


Phenotyping and outcomes of hospitalized COPD patients using rapid molecular diagnostics on sputum samples.

Alotaibi NM, Chen V, Hollander Z, Leipsic JA, Hague CJ, Murphy DT, DeMarco ML, FitzGerald JM, McManus BM, Ng RT, Sin DD.

Int J Chron Obstruct Pulmon Dis. 2019 Jan 23;14:311-319. doi: 10.2147/COPD.S188186. eCollection 2019.


Development and Validation of the Evaluation Platform in COPD (EPIC): A Population-Based Outcomes Model of COPD for Canada.

Sadatsafavi M, Ghanbarian S, Adibi A, Johnson K, FitzGerald JM, Flanagan W, Bryan S, Sin D; Canadian Respiratory Research Network.

Med Decis Making. 2019 Feb;39(2):152-167. doi: 10.1177/0272989X18824098. Epub 2019 Jan 24.


Psychological distress is related to poor health behaviours in COPD and non-COPD patients: Evidence from the CanCOLD study.

Paine NJ, Bacon SL, Bourbeau J, Tan WC, Lavoie KL; CanCOLD Study Investigators, Aaron SD, Chapman KR, FitzGerald JM, Hernandez P, Marciniuk DD, Maltais F, O'Donnell DE, Sin D, Walker BL; Canadian Respiratory Research Network and teh CanCOLD Collaborative Research Group.

Respir Med. 2019 Jan;146:1-9. doi: 10.1016/j.rmed.2018.11.006. Epub 2018 Nov 15.


Heterogeneity in the respiratory symptoms of patients with mild-to-moderate COPD.

Johnson KM, Safari A, Tan WC, Bourbeau J, FitzGerald JM, Sadatsafavi M, Study OBOTCCOOLDC; Canadian Respiratory Research Network.

Int J Chron Obstruct Pulmon Dis. 2018 Dec 13;13:3983-3995. doi: 10.2147/COPD.S184424. eCollection 2018.


A systematic review of the adverse events and economic impact associated with oral corticosteroids in asthma.

Al Efraij K, Johnson KM, Wiebe D, Sadatsafavi M, FitzGerald JM.

J Asthma. 2019 Dec;56(12):1334-1346. doi: 10.1080/02770903.2018.1539100. Epub 2018 Dec 4.


The Incidence of Recorded Delirium Episodes Before and After Dementia Diagnosis: Differences Between Dementia With Lewy Bodies and Alzheimer's Disease.

FitzGerald JM, Perera G, Chang-Tave A, Price A, Rajkumar AP, Bhattarai M, O'Brien JT, Ballard C, Aarsland D, Stewart R, Mueller C.

J Am Med Dir Assoc. 2019 May;20(5):604-609. doi: 10.1016/j.jamda.2018.09.021. Epub 2018 Nov 15.


Long-term safety and efficacy of benralizumab in patients with severe, uncontrolled asthma: 1-year results from the BORA phase 3 extension trial.

Busse WW, Bleecker ER, FitzGerald JM, Ferguson GT, Barker P, Sproule S, Olsson RF, Martin UJ, Goldman M; BORA study investigators.

Lancet Respir Med. 2019 Jan;7(1):46-59. doi: 10.1016/S2213-2600(18)30406-5. Epub 2018 Nov 8. Erratum in: Lancet Respir Med. 2019 Jan;7(1):e1.


Transdiagnostic neural correlates of volitional emotion regulation in anxiety and depression.

Fitzgerald JM, Klumpp H, Langenecker S, Phan KL.

Depress Anxiety. 2019 May;36(5):453-464. doi: 10.1002/da.22859. Epub 2018 Nov 8.


Sputum Microbiome Is Associated with 1-Year Mortality after Chronic Obstructive Pulmonary Disease Hospitalizations.

Leitao Filho FS, Alotaibi NM, Ngan D, Tam S, Yang J, Hollander Z, Chen V, FitzGerald JM, Nislow C, Leung JM, Man SFP, Sin DD.

Am J Respir Crit Care Med. 2019 May 15;199(10):1205-1213. doi: 10.1164/rccm.201806-1135OC.


Long-term effects of inhaled corticosteroids on bone mineral density in older women with asthma or COPD: a registry-based cohort study.

Chen W, Johnson KM, FitzGerald JM, Sadatsafavi M, Leslie WD.

Arch Osteoporos. 2018 Oct 29;13(1):116. doi: 10.1007/s11657-018-0537-2.


Principal component analysis and brain-based predictors of emotion regulation in anxiety and depression.

Klumpp H, Kinney KL, Bhaumik R, Fitzgerald JM.

Psychol Med. 2019 Oct;49(14):2320-2329. doi: 10.1017/S0033291718003148. Epub 2018 Oct 25.


Tiotropium add-on to inhaled corticosteroids versus addition of long-acting β2-agonists for adults with asthma.

Buhl R, FitzGerald JM, Busse WW.

Respir Med. 2018 Oct;143:82-90. doi: 10.1016/j.rmed.2018.08.014. Epub 2018 Aug 29. Review.


Development of the International Severe Asthma Registry (ISAR): A Modified Delphi Study.

Bulathsinhala L, Eleangovan N, Heaney LG, Menzies-Gow A, Gibson PG, Peters M, Hew M, van Boven JFM, Lehtimäki L, van Ganse E, Belhassen M, Harvey ES, Perez de Llano L, Maitland-van der Zee AH, Papadopoulos NG, FitzGerald JM, Porsbjerg C, Canonica GW, Backer V, Rhee CK, Verhamme KMC, Buhl R, Cosio BG, Carter V, Price C, Le T, Stagno d'Alcontres M, Gopalan G, Tran TN, Price D.

J Allergy Clin Immunol Pract. 2019 Feb;7(2):578-588.e2. doi: 10.1016/j.jaip.2018.08.016. Epub 2018 Sep 1.


As-Needed Budesonide-Formoterol in Mild Asthma.

Bateman ED, Reddel HK, FitzGerald JM.

N Engl J Med. 2018 Aug 30;379(9):898. doi: 10.1056/NEJMc1808073. No abstract available.


Neuroimaging Predictors and Mechanisms of Treatment Response in Social Anxiety Disorder: an Overview of the Amygdala.

Klumpp H, Fitzgerald JM.

Curr Psychiatry Rep. 2018 Aug 28;20(10):89. doi: 10.1007/s11920-018-0948-1. Review.


Baseline patient factors impact on the clinical efficacy of benralizumab for severe asthma.

Bleecker ER, Wechsler ME, FitzGerald JM, Menzies-Gow A, Wu Y, Hirsch I, Goldman M, Newbold P, Zangrilli JG.

Eur Respir J. 2018 Oct 18;52(4). pii: 1800936. doi: 10.1183/13993003.00936-2018. Print 2018 Oct.


A pilot randomized controlled trial on the impact of text messaging check-ins and a web-based asthma action plan versus a written action plan on asthma exacerbations.

Poureslami I PhD, Shum J MSc, Lester RT MD, Tavakoli H MD, MSc, Dorscheid DR MD, PhD, FitzGerald JM MD.

J Asthma. 2018 Oct 16:1-13. doi: 10.1080/02770903.2018.1500583. [Epub ahead of print]


Benralizumab for the add-on maintenance treatment of patients with severe asthma aged 12 years and older with an eosinophilic phenotype.

Al Efraij K, FitzGerald JM.

Expert Rev Clin Pharmacol. 2018 Jul;11(7):669-676. doi: 10.1080/17512433.2018.1496819. Epub 2018 Jul 11. Review.


Between-Visit Variability in FEV1 as a Diagnostic Test for Asthma in Adults.

Dean BW, Birnie EE, Whitmore GA, Vandemheen KL, Boulet LP, FitzGerald JM, Ainslie M, Gupta S, Lemiere C, Field SK, McIvor RA, Hernandez P, Mayers I, Aaron SD; Canadian Respiratory Research Network.

Ann Am Thorac Soc. 2018 Sep;15(9):1039-1046. doi: 10.1513/AnnalsATS.201803-211OC.


Working Memory Load and Negative Picture Processing: Neural and Behavioral Associations With Panic, Social Anxiety, and Positive Affect.

MacNamara A, Jackson TB, Fitzgerald JM, Hajcak G, Phan KL.

Biol Psychiatry Cogn Neurosci Neuroimaging. 2019 Feb;4(2):151-159. doi: 10.1016/j.bpsc.2018.04.005. Epub 2018 Apr 22.


Effect of tralokinumab, an interleukin-13 neutralising monoclonal antibody, on eosinophilic airway inflammation in uncontrolled moderate-to-severe asthma (MESOS): a multicentre, double-blind, randomised, placebo-controlled phase 2 trial.

Russell RJ, Chachi L, FitzGerald JM, Backer V, Olivenstein R, Titlestad IL, Ulrik CS, Harrison T, Singh D, Chaudhuri R, Leaker B, McGarvey L, Siddiqui S, Wang M, Braddock M, Nordenmark LH, Cohen D, Parikh H, Colice G, Brightling CE; MESOS study investigators.

Lancet Respir Med. 2018 Jul;6(7):499-510. doi: 10.1016/S2213-2600(18)30201-7. Epub 2018 May 21.


Health literacy in chronic disease management: a matter of interaction.

van der Heide I, Poureslami I, Mitic W, Shum J, Rootman I, FitzGerald JM.

J Clin Epidemiol. 2018 Oct;102:134-138. doi: 10.1016/j.jclinepi.2018.05.010. Epub 2018 May 21.


Inhaled Glucocorticoids in Asthma.

Boulet LP, Gupta S, FitzGerald JM.

N Engl J Med. 2018 May 24;378(21):2050-1. doi: 10.1056/NEJMc1804801. No abstract available.


Dupilumab Efficacy and Safety in Moderate-to-Severe Uncontrolled Asthma.

Castro M, Corren J, Pavord ID, Maspero J, Wenzel S, Rabe KF, Busse WW, Ford L, Sher L, FitzGerald JM, Katelaris C, Tohda Y, Zhang B, Staudinger H, Pirozzi G, Amin N, Ruddy M, Akinlade B, Khan A, Chao J, Martincova R, Graham NMH, Hamilton JD, Swanson BN, Stahl N, Yancopoulos GD, Teper A.

N Engl J Med. 2018 Jun 28;378(26):2486-2496. doi: 10.1056/NEJMoa1804092. Epub 2018 May 21.


Asthma in low-income and middle-income countries: an urgent call to action.

FitzGerald JM, Al Efraij K.

Thorax. 2018 Oct;73(10):898-899. doi: 10.1136/thoraxjnl-2018-211718. Epub 2018 May 18. No abstract available.


Inhaled Combined Budesonide-Formoterol as Needed in Mild Asthma.

O'Byrne PM, FitzGerald JM, Bateman ED, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Ivanov S, Reddel HK.

N Engl J Med. 2018 May 17;378(20):1865-1876. doi: 10.1056/NEJMoa1715274.


As-Needed Budesonide-Formoterol versus Maintenance Budesonide in Mild Asthma.

Bateman ED, Reddel HK, O'Byrne PM, Barnes PJ, Zhong N, Keen C, Jorup C, Lamarca R, Siwek-Posluszna A, FitzGerald JM.

N Engl J Med. 2018 May 17;378(20):1877-1887. doi: 10.1056/NEJMoa1715275.

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