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Items: 18


Investigation of Genetic Susceptibility to Blastomycosis Reveals Interleukin-6 as a Potential Susceptibility Locus.

Merkhofer RM Jr, O'Neill MB, Xiong D, Hernandez-Santos N, Dobson H, Fites JS, Shockey AC, Wuethrich M, Pepperell CS, Klein BS.

MBio. 2019 Jun 18;10(3). pii: e01224-19. doi: 10.1128/mBio.01224-19.


Virally-vectored vaccine candidates against white-nose syndrome induce anti-fungal immune response in little brown bats (Myotis lucifugus).

Rocke TE, Kingstad-Bakke B, Wüthrich M, Stading B, Abbott RC, Isidoro-Ayza M, Dobson HE, Dos Santos Dias L, Galles K, Lankton JS, Falendysz EA, Lorch JM, Fites JS, Lopera-Madrid J, White JP, Klein B, Osorio JE.

Sci Rep. 2019 May 1;9(1):6788. doi: 10.1038/s41598-019-43210-w.


Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.

Hernández-Santos N, Wiesner DL, Fites JS, McDermott AJ, Warner T, Wüthrich M, Klein BS.

Cell Host Microbe. 2019 Apr 10;25(4):630. doi: 10.1016/j.chom.2019.03.013. No abstract available.


Metabolites Involved in Immune Evasion by Batrachochytrium dendrobatidis Include the Polyamine Spermidine.

Rollins-Smith LA, Ruzzini AC, Fites JS, Reinert LK, Hall EM, Joosse BA, Ravikumar VI, Huebner MI, Aka A, Kehs MH, Gillard BM, Doe E, Tasca JA, Umile TP, Clardy J, Minbiole KPC.

Infect Immun. 2019 Apr 23;87(5). pii: e00035-19. doi: 10.1128/IAI.00035-19. Print 2019 Mar.


CBLB Constrains Inactivated Vaccine-Induced CD8+ T Cell Responses and Immunity against Lethal Fungal Pneumonia.

Nanjappa SG, Mudalagiriyappa S, Fites JS, Suresh M, Klein BS.

J Immunol. 2018 Sep 15;201(6):1717-1726. doi: 10.4049/jimmunol.1701241. Epub 2018 Jul 27.


An unappreciated role for neutrophil-DC hybrids in immunity to invasive fungal infections.

Fites JS, Gui M, Kernien JF, Negoro P, Dagher Z, Sykes DB, Nett JE, Mansour MK, Klein BS.

PLoS Pathog. 2018 May 21;14(5):e1007073. doi: 10.1371/journal.ppat.1007073. eCollection 2018 May.


Lung Epithelial Cells Coordinate Innate Lymphocytes and Immunity against Pulmonary Fungal Infection.

Hernández-Santos N, Wiesner DL, Fites JS, McDermott AJ, Warner T, Wüthrich M, Klein BS.

Cell Host Microbe. 2018 Apr 11;23(4):511-522.e5. doi: 10.1016/j.chom.2018.02.011. Epub 2018 Mar 22. Erratum in: Cell Host Microbe. 2019 Apr 10;25(4):630.


Antifungal Tc17 cells are durable and stable, persisting as long-lasting vaccine memory without plasticity towards IFNγ cells.

Nanjappa SG, McDermott AJ, Fites JS, Galles K, Wüthrich M, Deepe GS Jr, Klein BS.

PLoS Pathog. 2017 May 22;13(5):e1006356. doi: 10.1371/journal.ppat.1006356. eCollection 2017 May.


Human iNKT Cells Promote Protective Inflammation by Inducing Oscillating Purinergic Signaling in Monocyte-Derived DCs.

Xu X, Pocock GM, Sharma A, Peery SL, Fites JS, Felley L, Zarnowski R, Stewart D, Berthier E, Klein BS, Sherer NM, Gumperz JE.

Cell Rep. 2016 Sep 20;16(12):3273-3285. doi: 10.1016/j.celrep.2016.08.061.


Fungal Mimicry of a Mammalian Aminopeptidase Disables Innate Immunity and Promotes Pathogenicity.

Sterkel AK, Lorenzini JL, Fites JS, Subramanian Vignesh K, Sullivan TD, Wuthrich M, Brandhorst T, Hernandez-Santos N, Deepe GS Jr, Klein BS.

Cell Host Microbe. 2016 Mar 9;19(3):361-74. doi: 10.1016/j.chom.2016.02.001. Epub 2016 Feb 25.


Immunomodulatory metabolites released by the frog-killing fungus Batrachochytrium dendrobatidis.

Rollins-Smith LA, Fites JS, Reinert LK, Shiakolas AR, Umile TP, Minbiole KP.

Infect Immun. 2015 Dec;83(12):4565-70. doi: 10.1128/IAI.00877-15. Epub 2015 Sep 14.


Inhibition of local immune responses by the frog-killing fungus Batrachochytrium dendrobatidis.

Fites JS, Reinert LK, Chappell TM, Rollins-Smith LA.

Infect Immun. 2014 Nov;82(11):4698-706. doi: 10.1128/IAI.02231-14. Epub 2014 Aug 25.


Amphibians acquire resistance to live and dead fungus overcoming fungal immunosuppression.

McMahon TA, Sears BF, Venesky MD, Bessler SM, Brown JM, Deutsch K, Halstead NT, Lentz G, Tenouri N, Young S, Civitello DJ, Ortega N, Fites JS, Reinert LK, Rollins-Smith LA, Raffel TR, Rohr JR.

Nature. 2014 Jul 10;511(7508):224-7. doi: 10.1038/nature13491.


Nikkomycin Z is an effective inhibitor of the chytrid fungus linked to global amphibian declines.

Holden WM, Fites JS, Reinert LK, Rollins-Smith LA.

Fungal Biol. 2014 Jan;118(1):48-60. doi: 10.1016/j.funbio.2013.11.001. Epub 2013 Nov 18.


The invasive chytrid fungus of amphibians paralyzes lymphocyte responses.

Fites JS, Ramsey JP, Holden WM, Collier SP, Sutherland DM, Reinert LK, Gayek AS, Dermody TS, Aune TM, Oswald-Richter K, Rollins-Smith LA.

Science. 2013 Oct 18;342(6156):366-9. doi: 10.1126/science.1243316.


The yeast eukaryotic translation initiation factor 2B translation initiation complex interacts with the fatty acid synthesis enzyme YBR159W and endoplasmic reticulum membranes.

Browne CM, Samir P, Fites JS, Villarreal SA, Link AJ.

Mol Cell Biol. 2013 Mar;33(5):1041-56. doi: 10.1128/MCB.00811-12. Epub 2012 Dec 21.


Norepinephrine depletion of antimicrobial peptides from the skin glands of Xenopus laevis.

Gammill WM, Fites JS, Rollins-Smith LA.

Dev Comp Immunol. 2012 May;37(1):19-27. doi: 10.1016/j.dci.2011.12.012. Epub 2011 Dec 28.


Mitochondrial genome sequence of Unionicola foili (Acari: Unionicolidae): a unique gene order with implications for phylogenetic inference.

Ernsting BR, Edwards DD, Aldred KJ, Fites JS, Neff CR.

Exp Appl Acarol. 2009 Dec;49(4):305-16. doi: 10.1007/s10493-009-9263-1. Epub 2009 Apr 8.


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