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Items: 1 to 50 of 202

1.

αKlotho Regulates Age-Associated Vascular Calcification and Lifespan in Zebrafish.

Singh AP, Sosa MX, Fang J, Shanmukhappa SK, Hubaud A, Fawcett CH, Molind GJ, Tsai T, Capodieci P, Wetzel K, Sanchez E, Wang G, Coble M, Tang W, Cadena SM, Fishman MC, Glass DJ.

Cell Rep. 2019 Sep 10;28(11):2767-2776.e5. doi: 10.1016/j.celrep.2019.08.013.

2.

Mating Suppresses Alarm Response in Zebrafish.

Diaz-Verdugo C, Sun GJ, Fawcett CH, Zhu P, Fishman MC.

Curr Biol. 2019 Aug 5;29(15):2541-2546.e3. doi: 10.1016/j.cub.2019.06.047. Epub 2019 Jul 18.

3.

Abnormal Behavior of Zebrafish Mutant in Dopamine Transporter Is Rescued by Clozapine.

Wang G, Zhang G, Li Z, Fawcett CH, Coble M, Sosa MX, Tsai T, Malesky K, Thibodeaux SJ, Zhu P, Glass DJ, Fishman MC.

iScience. 2019 Jul 26;17:325-333. doi: 10.1016/j.isci.2019.06.039. Epub 2019 Jul 4.

4.

Prevalence of rheumatic heart disease in Zambian school children.

Musuku J, Engel ME, Musonda P, Lungu JC, Machila E, Schwaninger S, Mtaja A, Mulendele E, Kavindele D, Spector J, Tadmor B, Gutierrez MM, Van Dam J, Colin L, Long A, Fishman MC, Mayosi BM, Zühlke LJ.

BMC Cardiovasc Disord. 2018 Jul 3;18(1):135. doi: 10.1186/s12872-018-0871-8.

5.

The Great Opportunity: Cultivating Scientific Inquiry in Medical Residency.

Vyas JM, Rajagopal J, Sokol CL, Wein MN, Mansour MK, Corey KE, Fishman MC, Armstrong KA.

J Infect Dis. 2018 Aug 14;218(suppl_1):S44-S48. doi: 10.1093/infdis/jiy200.

6.

Fundamental science behind today's important medicines.

Spector JM, Harrison RS, Fishman MC.

Sci Transl Med. 2018 Apr 25;10(438). pii: eaaq1787. doi: 10.1126/scitranslmed.aaq1787. Review.

PMID:
29695453
7.

The mediator complex subunit Med10 regulates heart valve formation in zebrafish by controlling Tbx2b-mediated Has2 expression and cardiac jelly formation.

Just S, Hirth S, Berger IM, Fishman MC, Rottbauer W.

Biochem Biophys Res Commun. 2016 Sep 2;477(4):581-588. doi: 10.1016/j.bbrc.2016.06.088. Epub 2016 Jun 22.

8.

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Palacino J, Swalley SE, Song C, Cheung AK, Shu L, Zhang X, Van Hoosear M, Shin Y, Chin DN, Keller CG, Beibel M, Renaud NA, Smith TM, Salcius M, Shi X, Hild M, Servais R, Jain M, Deng L, Bullock C, McLellan M, Schuierer S, Murphy L, Blommers MJ, Blaustein C, Berenshteyn F, Lacoste A, Thomas JR, Roma G, Michaud GA, Tseng BS, Porter JA, Myer VE, Tallarico JA, Hamann LG, Curtis D, Fishman MC, Dietrich WF, Dales NA, Sivasankaran R.

Nat Chem Biol. 2016 Apr;12(4):304. doi: 10.1038/nchembio0416-304c. No abstract available.

PMID:
26991088
9.

Improving paediatric asthma care in Zambia.

Wa Somwe S, Jumbe-Marsden E, Mateyo K, Senkwe MN, Sotomayor-Ruiz M, Musuku J, Soriano JB, Ancochea J, Fishman MC.

Bull World Health Organ. 2015 Oct 1;93(10):732-736. Epub 2015 Aug 19.

10.

Corrigendum: SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Palacino J, Swalley SE, Song C, Cheung AK, Shu L, Zhang X, Van Hoosear M, Shin Y, Chin DN, Keller CG, Beibel M, Renaud NA, Smith TM, Salcius M, Shi X, Hild M, Servais R, Jain M, Deng L, Bullock C, McLellan M, Schuierer S, Murphy L, Blommers MJ, Blaustein C, Berenshteyn F, Lacoste A, Thomas JR, Roma G, Michaud GA, Tseng BS, Porter JA, Myer VE, Tallarico JA, Hamann LG, Curtis D, Fishman MC, Dietrich WF, Dales NA, Sivasankaran R.

Nat Chem Biol. 2015 Sep;11(9):741. doi: 10.1038/nchembio0915-741a. No abstract available.

PMID:
26284678
11.

SMN2 splice modulators enhance U1-pre-mRNA association and rescue SMA mice.

Palacino J, Swalley SE, Song C, Cheung AK, Shu L, Zhang X, Van Hoosear M, Shin Y, Chin DN, Keller CG, Beibel M, Renaud NA, Smith TM, Salcius M, Shi X, Hild M, Servais R, Jain M, Deng L, Bullock C, McLellan M, Schuierer S, Murphy L, Blommers MJ, Blaustein C, Berenshteyn F, Lacoste A, Thomas JR, Roma G, Michaud GA, Tseng BS, Porter JA, Myer VE, Tallarico JA, Hamann LG, Curtis D, Fishman MC, Dietrich WF, Dales NA, Sivasankaran R.

Nat Chem Biol. 2015 Jul;11(7):511-7. doi: 10.1038/nchembio.1837. Epub 2015 Jun 1. Erratum in: Nat Chem Biol. 2015 Sep;11(9):741. Nat Chem Biol. 2016 Apr;12(4):304.

PMID:
26030728
12.

Author response to comment on "Power of rare diseases: found in translation".

Fishman MC.

Sci Transl Med. 2014 Mar 19;6(228):228lr1. doi: 10.1126/scitranslmed.3008809.

13.

High-resolution chemical dissection of a model eukaryote reveals targets, pathways and gene functions.

Hoepfner D, Helliwell SB, Sadlish H, Schuierer S, Filipuzzi I, Brachat S, Bhullar B, Plikat U, Abraham Y, Altorfer M, Aust T, Baeriswyl L, Cerino R, Chang L, Estoppey D, Eichenberger J, Frederiksen M, Hartmann N, Hohendahl A, Knapp B, Krastel P, Melin N, Nigsch F, Oakeley EJ, Petitjean V, Petersen F, Riedl R, Schmitt EK, Staedtler F, Studer C, Tallarico JA, Wetzel S, Fishman MC, Porter JA, Movva NR.

Microbiol Res. 2014 Feb-Mar;169(2-3):107-20. doi: 10.1016/j.micres.2013.11.004. Epub 2013 Dec 1.

14.

Power of rare diseases: found in translation.

Fishman MC.

Sci Transl Med. 2013 Sep 4;5(201):201ps11. doi: 10.1126/scitranslmed.3006800.

PMID:
24005157
15.

Selective and specific inhibition of the plasmodium falciparum lysyl-tRNA synthetase by the fungal secondary metabolite cladosporin.

Hoepfner D, McNamara CW, Lim CS, Studer C, Riedl R, Aust T, McCormack SL, Plouffe DM, Meister S, Schuierer S, Plikat U, Hartmann N, Staedtler F, Cotesta S, Schmitt EK, Petersen F, Supek F, Glynne RJ, Tallarico JA, Porter JA, Fishman MC, Bodenreider C, Diagana TT, Movva NR, Winzeler EA.

Cell Host Microbe. 2012 Jun 14;11(6):654-63. doi: 10.1016/j.chom.2012.04.015.

16.

Designing zebrafish chemical screens.

Peterson RT, Fishman MC.

Methods Cell Biol. 2011;105:525-41. doi: 10.1016/B978-0-12-381320-6.00023-0.

PMID:
21951546
17.

The myosin-interacting protein SMYD1 is essential for sarcomere organization.

Just S, Meder B, Berger IM, Etard C, Trano N, Patzel E, Hassel D, Marquart S, Dahme T, Vogel B, Fishman MC, Katus HA, Strähle U, Rottbauer W.

J Cell Sci. 2011 Sep 15;124(Pt 18):3127-36. doi: 10.1242/jcs.084772. Epub 2011 Aug 18.

18.

Distinct troponin C isoform requirements in cardiac and skeletal muscle.

Sogah VM, Serluca FC, Fishman MC, Yelon DL, Macrae CA, Mably JD.

Dev Dyn. 2010 Nov;239(11):3115-23. doi: 10.1002/dvdy.22445.

19.

Mutations in zebrafish leucine-rich repeat-containing six-like affect cilia motility and result in pronephric cysts, but have variable effects on left-right patterning.

Serluca FC, Xu B, Okabe N, Baker K, Lin SY, Sullivan-Brown J, Konieczkowski DJ, Jaffe KM, Bradner JM, Fishman MC, Burdine RD.

Development. 2009 May;136(10):1621-31. doi: 10.1242/dev.020735.

20.

A single serine in the carboxyl terminus of cardiac essential myosin light chain-1 controls cardiomyocyte contractility in vivo.

Meder B, Laufer C, Hassel D, Just S, Marquart S, Vogel B, Hess A, Fishman MC, Katus HA, Rottbauer W.

Circ Res. 2009 Mar 13;104(5):650-9. doi: 10.1161/CIRCRESAHA.108.186676. Epub 2009 Jan 22.

PMID:
19168438
21.

Genetic steps to organ laterality in zebrafish.

Chen JN, van Bebber F, Goldstein AM, Serluca FC, Jackson D, Childs S, Serbedzija G, Warren KS, Mably JD, Lindahl P, Mayer A, Haffter P, Fishman MC.

Comp Funct Genomics. 2001;2(2):60-8. doi: 10.1002/cfg.74.

22.

Deficient zebrafish ether-à-go-go-related gene channel gating causes short-QT syndrome in zebrafish reggae mutants.

Hassel D, Scholz EP, Trano N, Friedrich O, Just S, Meder B, Weiss DL, Zitron E, Marquart S, Vogel B, Karle CA, Seemann G, Fishman MC, Katus HA, Rottbauer W.

Circulation. 2008 Feb 19;117(7):866-75. doi: 10.1161/CIRCULATIONAHA.107.752220. Epub 2008 Feb 4.

PMID:
18250272
23.

Integrin-linked kinase, a novel component of the cardiac mechanical stretch sensor, controls contractility in the zebrafish heart.

Bendig G, Grimmler M, Huttner IG, Wessels G, Dahme T, Just S, Trano N, Katus HA, Fishman MC, Rottbauer W.

Genes Dev. 2006 Sep 1;20(17):2361-72. Epub 2006 Aug 18.

24.

santa and valentine pattern concentric growth of cardiac myocardium in the zebrafish.

Mably JD, Chuang LP, Serluca FC, Mohideen MA, Chen JN, Fishman MC.

Development. 2006 Aug;133(16):3139-46.

25.

Cardiac myosin light chain-2: a novel essential component of thick-myofilament assembly and contractility of the heart.

Rottbauer W, Wessels G, Dahme T, Just S, Trano N, Hassel D, Burns CG, Katus HA, Fishman MC.

Circ Res. 2006 Aug 4;99(3):323-31. Epub 2006 Jun 29.

PMID:
16809551
26.

Big, bad hearts: from flies to man.

Serluca FC, Fishman MC.

Proc Natl Acad Sci U S A. 2006 Mar 14;103(11):3947-8. Epub 2006 Mar 6. No abstract available.

27.

High-throughput assay for small molecules that modulate zebrafish embryonic heart rate.

Burns CG, Milan DJ, Grande EJ, Rottbauer W, MacRae CA, Fishman MC.

Nat Chem Biol. 2005 Oct;1(5):263-4. Epub 2005 Sep 18.

PMID:
16408054
28.

Calcium extrusion is critical for cardiac morphogenesis and rhythm in embryonic zebrafish hearts.

Ebert AM, Hume GL, Warren KS, Cook NP, Burns CG, Mohideen MA, Siegal G, Yelon D, Fishman MC, Garrity DM.

Proc Natl Acad Sci U S A. 2005 Dec 6;102(49):17705-10. Epub 2005 Nov 28.

29.

Pharmaceuticals: a new grammar for drug discovery.

Fishman MC, Porter JA.

Nature. 2005 Sep 22;437(7058):491-3. No abstract available.

PMID:
16177777
30.

VEGF-PLCgamma1 pathway controls cardiac contractility in the embryonic heart.

Rottbauer W, Just S, Wessels G, Trano N, Most P, Katus HA, Fishman MC.

Genes Dev. 2005 Jul 1;19(13):1624-34.

31.

Discovery and use of small molecules for probing biological processes in zebrafish.

Peterson RT, Fishman MC.

Methods Cell Biol. 2004;76:569-91. No abstract available.

PMID:
15602893
32.

Semaphorin-plexin signaling guides patterning of the developing vasculature.

Torres-Vázquez J, Gitler AD, Fraser SD, Berk JD, Van N Pham, Fishman MC, Childs S, Epstein JA, Weinstein BM.

Dev Cell. 2004 Jul;7(1):117-23.

33.

Mark C. Fishman.

Fishman MC.

Nat Rev Drug Discov. 2004 Apr;3(4):292. No abstract available.

PMID:
15124621
34.

Chemical suppression of a genetic mutation in a zebrafish model of aortic coarctation.

Peterson RT, Shaw SY, Peterson TA, Milan DJ, Zhong TP, Schreiber SL, MacRae CA, Fishman MC.

Nat Biotechnol. 2004 May;22(5):595-9. Epub 2004 Apr 18.

35.

heart of glass regulates the concentric growth of the heart in zebrafish.

Mably JD, Mohideen MA, Burns CG, Chen JN, Fishman MC.

Curr Biol. 2003 Dec 16;13(24):2138-47.

37.

Zebrafish: the complete cardiovascular compendium.

MacRae CA, Fishman MC.

Cold Spring Harb Symp Quant Biol. 2002;67:301-7. Review. No abstract available.

PMID:
12858553
38.

The limb identity gene Tbx5 promotes limb initiation by interacting with Wnt2b and Fgf10.

Ng JK, Kawakami Y, Büscher D, Raya A, Itoh T, Koth CM, Rodríguez Esteban C, Rodríguez-León J, Garrity DM, Fishman MC, Izpisúa Belmonte JC.

Development. 2002 Nov;129(22):5161-70.

39.

Cardiovascular system.

Yelon D, Weinstein BM, Fishman MC.

Results Probl Cell Differ. 2002;40:298-321. Review. No abstract available.

PMID:
12353483
40.

The heartstrings mutation in zebrafish causes heart/fin Tbx5 deficiency syndrome.

Garrity DM, Childs S, Fishman MC.

Development. 2002 Oct;129(19):4635-45.

41.

From Zebrafish to human: modular medical models.

Shin JT, Fishman MC.

Annu Rev Genomics Hum Genet. 2002;3:311-40. Epub 2002 Apr 15. Review.

PMID:
12142362
42.

In vivo imaging of proteolytic activity in atherosclerosis.

Chen J, Tung CH, Mahmood U, Ntziachristos V, Gyurko R, Fishman MC, Huang PL, Weissleder R.

Circulation. 2002 Jun 11;105(23):2766-71.

PMID:
12057992
43.

Disruption of acvrl1 increases endothelial cell number in zebrafish cranial vessels.

Roman BL, Pham VN, Lawson ND, Kulik M, Childs S, Lekven AC, Garrity DM, Moon RT, Fishman MC, Lechleider RJ, Weinstein BM.

Development. 2002 Jun;129(12):3009-19.

44.

Endothelial signaling in kidney morphogenesis: a role for hemodynamic forces.

Serluca FC, Drummond IA, Fishman MC.

Curr Biol. 2002 Mar 19;12(6):492-7.

45.

Patterning of angiogenesis in the zebrafish embryo.

Childs S, Chen JN, Garrity DM, Fishman MC.

Development. 2002 Feb;129(4):973-82.

46.

Cardiomyopathy in zebrafish due to mutation in an alternatively spliced exon of titin.

Xu X, Meiler SE, Zhong TP, Mohideen M, Crossley DA, Burggren WW, Fishman MC.

Nat Genet. 2002 Feb;30(2):205-9. Epub 2002 Jan 14.

PMID:
11788825
47.

Growth and function of the embryonic heart depend upon the cardiac-specific L-type calcium channel alpha1 subunit.

Rottbauer W, Baker K, Wo ZG, Mohideen MA, Cantiello HF, Fishman MC.

Dev Cell. 2001 Aug;1(2):265-75.

48.

Genomics. Zebrafish--the canonical vertebrate.

Fishman MC.

Science. 2001 Nov 9;294(5545):1290-1. No abstract available.

PMID:
11701913
49.

Gridlock signalling pathway fashions the first embryonic artery.

Zhong TP, Childs S, Leu JP, Fishman MC.

Nature. 2001 Nov 8;414(6860):216-20.

PMID:
11700560
50.

Partitioning of tissue expression accompanies multiple duplications of the Na+/K+ ATPase alpha subunit gene.

Serluca FC, Sidow A, Mably JD, Fishman MC.

Genome Res. 2001 Oct;11(10):1625-31.

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