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Items: 1 to 50 of 123

1.

Whole-Blood Transcriptome Profiling Identifies Women With Myocardial Infarction With Nonobstructive Coronary Artery Disease.

Barrett TJ, Lee AH, Smilowitz NR, Hausvater A, Fishman GI, Hochman JS, Reynolds HR, Berger JS.

Circ Genom Precis Med. 2018 Dec;11(12):e002387. doi: 10.1161/CIRCGEN.118.002387. No abstract available.

PMID:
30562118
2.

ETV1 activates a rapid conduction transcriptional program in rodent and human cardiomyocytes.

Shekhar A, Lin X, Lin B, Liu FY, Zhang J, Khodadadi-Jamayran A, Tsirigos A, Bu L, Fishman GI, Park DS.

Sci Rep. 2018 Jul 2;8(1):9944. doi: 10.1038/s41598-018-28239-7.

3.

Telephone-based mindfulness training to reduce stress in women with myocardial infarction: Rationale and design of a multicenter randomized controlled trial.

Spruill TM, Reynolds HR, Dickson VV, Shallcross AJ, Visvanathan PD, Park C, Kalinowski J, Zhong H, Berger JS, Hochman JS, Fishman GI, Ogedegbe G.

Am Heart J. 2018 Aug;202:61-67. doi: 10.1016/j.ahj.2018.03.028. Epub 2018 Apr 21.

PMID:
29864732
4.

SCN5A: the greatest HITS collection.

Park DS, Fishman GI.

J Clin Invest. 2018 Mar 1;128(3):913-915. doi: 10.1172/JCI99927. Epub 2018 Feb 19.

5.

Development and Function of the Cardiac Conduction System in Health and Disease.

Park DS, Fishman GI.

J Cardiovasc Dev Dis. 2017;4(2). pii: 7. doi: 10.3390/jcdd4020007. Epub 2017 Jun 7.

6.

Drug-Induced Arrhythmias, Precision Medicine, and Small Data.

Fishman GI.

Circ Arrhythm Electrophysiol. 2017 Apr;10(4). pii: e005208. doi: 10.1161/CIRCEP.117.005208. No abstract available.

7.

Transcription factor ETV1 is essential for rapid conduction in the heart.

Shekhar A, Lin X, Liu FY, Zhang J, Mo H, Bastarache L, Denny JC, Cox NJ, Delmar M, Roden DM, Fishman GI, Park DS.

J Clin Invest. 2016 Dec 1;126(12):4444-4459. doi: 10.1172/JCI87968. Epub 2016 Oct 24.

8.

Fhf2 gene deletion causes temperature-sensitive cardiac conduction failure.

Park DS, Shekhar A, Marra C, Lin X, Vasquez C, Solinas S, Kelley K, Morley G, Goldfarb M, Fishman GI.

Nat Commun. 2016 Oct 4;7:12966. doi: 10.1038/ncomms12966.

9.

Purkinje Cells as Sources of Arrhythmias in Long QT Syndrome Type 3.

Iyer V, Roman-Campos D, Sampson KJ, Kang G, Fishman GI, Kass RS.

Sci Rep. 2015 Aug 20;5:13287. doi: 10.1038/srep13287.

10.

Efficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling.

Tsai SY, Maass K, Lu J, Fishman GI, Chen S, Evans T.

Stem Cell Reports. 2015 Jun 9;4(6):1089-102. doi: 10.1016/j.stemcr.2015.04.015. Epub 2015 May 28.

11.

Scn1b deletion leads to increased tetrodotoxin-sensitive sodium current, altered intracellular calcium homeostasis and arrhythmias in murine hearts.

Lin X, O'Malley H, Chen C, Auerbach D, Foster M, Shekhar A, Zhang M, Coetzee W, Jalife J, Fishman GI, Isom L, Delmar M.

J Physiol. 2015 Mar 15;593(6):1389-407. doi: 10.1113/jphysiol.2014.277699. Epub 2014 Sep 17.

12.

Isolation and characterization of embryonic stem cell-derived cardiac Purkinje cells.

Maass K, Shekhar A, Lu J, Kang G, See F, Kim EE, Delgado C, Shen S, Cohen L, Fishman GI.

Stem Cells. 2015 Apr;33(4):1102-12. doi: 10.1002/stem.1921.

13.

Genetically engineered SCN5A mutant pig hearts exhibit conduction defects and arrhythmias.

Park DS, Cerrone M, Morley G, Vasquez C, Fowler S, Liu N, Bernstein SA, Liu FY, Zhang J, Rogers CS, Priori SG, Chinitz LA, Fishman GI.

J Clin Invest. 2015 Jan;125(1):403-12. doi: 10.1172/JCI76919. Epub 2014 Dec 15.

14.

PCP4 regulates Purkinje cell excitability and cardiac rhythmicity.

Kim EE, Shekhar A, Lu J, Lin X, Liu FY, Zhang J, Delmar M, Fishman GI.

J Clin Invest. 2014 Nov;124(11):5027-36. doi: 10.1172/JCI77495. Epub 2014 Oct 8.

15.

Identification and purification of human induced pluripotent stem cell-derived atrial-like cardiomyocytes based on sarcolipin expression.

Josowitz R, Lu J, Falce C, D'Souza SL, Wu M, Cohen N, Dubois NC, Zhao Y, Sobie EA, Fishman GI, Gelb BD.

PLoS One. 2014 Jul 10;9(7):e101316. doi: 10.1371/journal.pone.0101316. eCollection 2014.

16.

Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias.

Hartman ME, Liu Y, Zhu WZ, Chien WM, Weldy CS, Fishman GI, Laflamme MA, Chin MT.

FASEB J. 2014 Jul;28(7):3007-15. doi: 10.1096/fj.14-251728. Epub 2014 Mar 31.

17.

Nav-igating through a complex landscape: SCN10A and cardiac conduction.

Park DS, Fishman GI.

J Clin Invest. 2014 Apr;124(4):1460-2. doi: 10.1172/JCI75240. Epub 2014 Mar 18.

18.

Myogenic bladder defects in mouse models of human oculodentodigital dysplasia.

Huang T, Shao Q, Barr K, Simek J, Fishman GI, Laird DW.

Biochem J. 2014 Feb 1;457(3):441-9. doi: 10.1042/BJ20130810.

19.

Pocket proteins critically regulate cell cycle exit of the trabecular myocardium and the ventricular conduction system.

Park DS, Tompkins RO, Liu F, Zhang J, Phoon CK, Zavadil J, Fishman GI.

Biol Open. 2013 Jul 31;2(9):968-78. doi: 10.1242/bio.20135785. eCollection 2013.

20.

GATA factors efficiently direct cardiac fate from embryonic stem cells.

Turbendian HK, Gordillo M, Tsai SY, Lu J, Kang G, Liu TC, Tang A, Liu S, Fishman GI, Evans T.

Development. 2013 Apr;140(8):1639-44. doi: 10.1242/dev.093260. Epub 2013 Mar 13.

21.

Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis.

Danielson LS, Park DS, Rotllan N, Chamorro-Jorganes A, Guijarro MV, Fernandez-Hernando C, Fishman GI, Phoon CK, Hernando E.

FASEB J. 2013 Apr;27(4):1460-7. doi: 10.1096/fj.12-221994. Epub 2012 Dec 27.

22.

Designer gap junctions that prevent cardiac arrhythmias.

Kim E, Fishman GI.

Trends Cardiovasc Med. 2013 Feb;23(2):33-8. doi: 10.1016/j.tcm.2012.08.008. Epub 2012 Dec 13. Review.

23.

The severity of mammary gland developmental defects is linked to the overall functional status of Cx43 as revealed by genetically modified mice.

Stewart MK, Gong XQ, Barr KJ, Bai D, Fishman GI, Laird DW.

Biochem J. 2013 Jan 15;449(2):401-13. doi: 10.1042/BJ20121070.

24.

Myocardial Notch signaling reprograms cardiomyocytes to a conduction-like phenotype.

Rentschler S, Yen AH, Lu J, Petrenko NB, Lu MM, Manderfield LJ, Patel VV, Fishman GI, Epstein JA.

Circulation. 2012 Aug 28;126(9):1058-66. doi: 10.1161/CIRCULATIONAHA.112.103390. Epub 2012 Jul 26.

25.

Characterization of gap junction proteins in the bladder of Cx43 mutant mouse models of oculodentodigital dysplasia.

Lorentz R, Shao Q, Huang T, Fishman GI, Laird DW.

J Membr Biol. 2012 Jun;245(5-6):345-55. doi: 10.1007/s00232-012-9455-1. Epub 2012 Jul 3.

26.

Connexin43 cardiac gap junction remodeling: lessons from genetically engineered murine models.

Remo BF, Giovannone S, Fishman GI.

J Membr Biol. 2012 Jun;245(5-6):275-81. doi: 10.1007/s00232-012-9448-0. Epub 2012 Jun 22. Review.

27.

Forever young: induced pluripotent stem cells as models of inherited arrhythmias.

Park DS, Fishman GI.

Circulation. 2012 Jun 26;125(25):3055-6. doi: 10.1161/CIRCULATIONAHA.112.114165. Epub 2012 May 30. No abstract available.

28.

Connexin-43 prevents hematopoietic stem cell senescence through transfer of reactive oxygen species to bone marrow stromal cells.

Taniguchi Ishikawa E, Gonzalez-Nieto D, Ghiaur G, Dunn SK, Ficker AM, Murali B, Madhu M, Gutstein DE, Fishman GI, Barrio LC, Cancelas JA.

Proc Natl Acad Sci U S A. 2012 Jun 5;109(23):9071-6. doi: 10.1073/pnas.1120358109. Epub 2012 May 18.

29.

Connexin-43 in the osteogenic BM niche regulates its cellular composition and the bidirectional traffic of hematopoietic stem cells and progenitors.

Gonzalez-Nieto D, Li L, Kohler A, Ghiaur G, Ishikawa E, Sengupta A, Madhu M, Arnett JL, Santho RA, Dunn SK, Fishman GI, Gutstein DE, Civitelli R, Barrio LC, Gunzer M, Cancelas JA.

Blood. 2012 May 31;119(22):5144-54. doi: 10.1182/blood-2011-07-368506. Epub 2012 Apr 12.

30.

Channeling diversity: gap junction expression in the heart.

Giovannone S, Remo BF, Fishman GI.

Heart Rhythm. 2012 Jul;9(7):1159-62. doi: 10.1016/j.hrthm.2011.11.040. Epub 2011 Nov 23. No abstract available.

31.

Full report from the first annual Heart Rhythm Society Research Forum: a vision for our research future, "dream, discover, develop, deliver".

Albert CM, Chen PS, Anderson ME, Cain ME, Fishman GI, Narayan SM, Olgin JE, Spooner PM, Stevenson WG, Van Wagoner DR, Packer DL; Heart Rhythm Society Research Task Force.

Heart Rhythm. 2011 Dec;8(12):e1-12. doi: 10.1016/j.hrthm.2011.10.024. Epub 2011 Nov 7. No abstract available.

32.

Unique properties of the ATP-sensitive K⁺ channel in the mouse ventricular cardiac conduction system.

Bao L, Kefaloyianni E, Lader J, Hong M, Morley G, Fishman GI, Sobie EA, Coetzee WA.

Circ Arrhythm Electrophysiol. 2011 Dec;4(6):926-35. doi: 10.1161/CIRCEP.111.964643. Epub 2011 Oct 9.

33.

Subcellular heterogeneity of sodium current properties in adult cardiac ventricular myocytes.

Lin X, Liu N, Lu J, Zhang J, Anumonwo JM, Isom LL, Fishman GI, Delmar M.

Heart Rhythm. 2011 Dec;8(12):1923-30. doi: 10.1016/j.hrthm.2011.07.016. Epub 2011 Jul 20.

34.

Remodeling of atrial ATP-sensitive K⁺ channels in a model of salt-induced elevated blood pressure.

Lader JM, Vasquez C, Bao L, Maass K, Qu J, Kefalogianni E, Fishman GI, Coetzee WA, Morley GE.

Am J Physiol Heart Circ Physiol. 2011 Sep;301(3):H964-74. doi: 10.1152/ajpheart.00410.2011. Epub 2011 Jul 1.

35.

The power of Pasteur's quadrant: cardiovascular disease at the turn of the century.

Levin RI, Fishman GI.

FASEB J. 2011 Jun;25(6):1788-92. doi: 10.1096/fj.11-0604ufm.

36.

Phosphatase-resistant gap junctions inhibit pathological remodeling and prevent arrhythmias.

Remo BF, Qu J, Volpicelli FM, Giovannone S, Shin D, Lader J, Liu FY, Zhang J, Lent DS, Morley GE, Fishman GI.

Circ Res. 2011 Jun 10;108(12):1459-66. doi: 10.1161/CIRCRESAHA.111.244046. Epub 2011 Apr 28.

37.

The sarcoplasmic reticulum luminal thiol oxidase ERO1 regulates cardiomyocyte excitation-coupled calcium release and response to hemodynamic load.

Chin KT, Kang G, Qu J, Gardner LB, Coetzee WA, Zito E, Fishman GI, Ron D.

FASEB J. 2011 Aug;25(8):2583-91. doi: 10.1096/fj.11-184622. Epub 2011 Apr 20.

38.

The cardiac conduction system.

Park DS, Fishman GI.

Circulation. 2011 Mar 1;123(8):904-15. doi: 10.1161/CIRCULATIONAHA.110.942284. Review. No abstract available.

39.

Sudden cardiac death prediction and prevention: report from a National Heart, Lung, and Blood Institute and Heart Rhythm Society Workshop.

Fishman GI, Chugh SS, Dimarco JP, Albert CM, Anderson ME, Bonow RO, Buxton AE, Chen PS, Estes M, Jouven X, Kwong R, Lathrop DA, Mascette AM, Nerbonne JM, O'Rourke B, Page RL, Roden DM, Rosenbaum DS, Sotoodehnia N, Trayanova NA, Zheng ZJ.

Circulation. 2010 Nov 30;122(22):2335-48. doi: 10.1161/CIRCULATIONAHA.110.976092. No abstract available.

40.

Common variants in 22 loci are associated with QRS duration and cardiac ventricular conduction.

Sotoodehnia N, Isaacs A, de Bakker PI, Dörr M, Newton-Cheh C, Nolte IM, van der Harst P, Müller M, Eijgelsheim M, Alonso A, Hicks AA, Padmanabhan S, Hayward C, Smith AV, Polasek O, Giovannone S, Fu J, Magnani JW, Marciante KD, Pfeufer A, Gharib SA, Teumer A, Li M, Bis JC, Rivadeneira F, Aspelund T, Köttgen A, Johnson T, Rice K, Sie MP, Wang YA, Klopp N, Fuchsberger C, Wild SH, Mateo Leach I, Estrada K, Völker U, Wright AF, Asselbergs FW, Qu J, Chakravarti A, Sinner MF, Kors JA, Petersmann A, Harris TB, Soliman EZ, Munroe PB, Psaty BM, Oostra BA, Cupples LA, Perz S, de Boer RA, Uitterlinden AG, Völzke H, Spector TD, Liu FY, Boerwinkle E, Dominiczak AF, Rotter JI, van Herpen G, Levy D, Wichmann HE, van Gilst WH, Witteman JC, Kroemer HK, Kao WH, Heckbert SR, Meitinger T, Hofman A, Campbell H, Folsom AR, van Veldhuisen DJ, Schwienbacher C, O'Donnell CJ, Volpato CB, Caulfield MJ, Connell JM, Launer L, Lu X, Franke L, Fehrmann RS, te Meerman G, Groen HJ, Weersma RK, van den Berg LH, Wijmenga C, Ophoff RA, Navis G, Rudan I, Snieder H, Wilson JF, Pramstaller PP, Siscovick DS, Wang TJ, Gudnason V, van Duijn CM, Felix SB, Fishman GI, Jamshidi Y, Stricker BH, Samani NJ, Kääb S, Arking DE.

Nat Genet. 2010 Dec;42(12):1068-76. doi: 10.1038/ng.716. Epub 2010 Nov 14.

41.

Purkinje cells from RyR2 mutant mice are highly arrhythmogenic but responsive to targeted therapy.

Kang G, Giovannone SF, Liu N, Liu FY, Zhang J, Priori SG, Fishman GI.

Circ Res. 2010 Aug 20;107(4):512-9. doi: 10.1161/CIRCRESAHA.110.221481. Epub 2010 Jul 1.

42.

Contactin-2 expression in the cardiac Purkinje fiber network.

Pallante BA, Giovannone S, Fang-Yu L, Zhang J, Liu N, Kang G, Dun W, Boyden PA, Fishman GI.

Circ Arrhythm Electrophysiol. 2010 Apr;3(2):186-94. doi: 10.1161/CIRCEP.109.928820. Epub 2010 Jan 28.

43.

A colorful explanation for atrial arrhythmias.

Remo BF, Fishman GI.

Pigment Cell Melanoma Res. 2010 Feb;23(1):3-4. doi: 10.1111/j.1755-148X.2009.00658.x. Epub 2009 Dec 2. No abstract available.

44.

Gap junction remodeling and spironolactone-dependent reverse remodeling in the hypertrophied heart.

Qu J, Volpicelli FM, Garcia LI, Sandeep N, Zhang J, Márquez-Rosado L, Lampe PD, Fishman GI.

Circ Res. 2009 Feb 13;104(3):365-71. doi: 10.1161/CIRCRESAHA.108.184044. Epub 2008 Dec 18.

45.

Ephaptic conduction in a cardiac strand model with 3D electrodiffusion.

Mori Y, Fishman GI, Peskin CS.

Proc Natl Acad Sci U S A. 2008 Apr 29;105(17):6463-8. doi: 10.1073/pnas.0801089105. Epub 2008 Apr 23.

46.

Lamin A/C haploinsufficiency causes dilated cardiomyopathy and apoptosis-triggered cardiac conduction system disease.

Wolf CM, Wang L, Alcalai R, Pizard A, Burgon PG, Ahmad F, Sherwood M, Branco DM, Wakimoto H, Fishman GI, See V, Stewart CL, Conner DA, Berul CI, Seidman CE, Seidman JG.

J Mol Cell Cardiol. 2008 Feb;44(2):293-303. doi: 10.1016/j.yjmcc.2007.11.008. Epub 2007 Dec 3.

47.

Gap junction remodeling and cardiac arrhythmogenesis in a murine model of oculodentodigital dysplasia.

Kalcheva N, Qu J, Sandeep N, Garcia L, Zhang J, Wang Z, Lampe PD, Suadicani SO, Spray DC, Fishman GI.

Proc Natl Acad Sci U S A. 2007 Dec 18;104(51):20512-6. Epub 2007 Dec 11.

48.

Abnormal conduction and morphology in the atrioventricular node of mice with atrioventricular canal targeted deletion of Alk3/Bmpr1a receptor.

Stroud DM, Gaussin V, Burch JB, Yu C, Mishina Y, Schneider MD, Fishman GI, Morley GE.

Circulation. 2007 Nov 27;116(22):2535-43. Epub 2007 Nov 12.

49.

Electrical remodeling contributes to complex tachyarrhythmias in connexin43-deficient mouse hearts.

Danik SB, Rosner G, Lader J, Gutstein DE, Fishman GI, Morley GE.

FASEB J. 2008 Apr;22(4):1204-12. Epub 2007 Nov 5.

50.

Transfection of mammalian cells with connexins and measurement of voltage sensitivity of their gap junctions.

del Corsso C, Srinivas M, Urban-Maldonado M, Moreno AP, Fort AG, Fishman GI, Spray DC.

Nat Protoc. 2006;1(4):1799-809.

PMID:
17487162

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