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Lack of group-to-individual generalizability is a threat to human subjects research.

Fisher AJ, Medaglia JD, Jeronimus BF.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):E6106-E6115. doi: 10.1073/pnas.1711978115. Epub 2018 Jun 18.


Structural basis for eukaryotic mRNA modification.

Fisher AJ, Beal PA.

Curr Opin Struct Biol. 2018 Jun 15;53:59-68. doi: 10.1016/ [Epub ahead of print] Review.


Outcomes of lung transplantation in adults with bronchiectasis.

Birch J, Sunny SS, Hester KLM, Parry G, Kate Gould F, Dark JH, Clark SC, Meachery G, Lordan J, Fisher AJ, Corris PA, De Soyza A.

BMC Pulm Med. 2018 May 22;18(1):82. doi: 10.1186/s12890-018-0634-4.


Using network analysis for the prediction of treatment dropout in patients with mood and anxiety disorders: A methodological proof-of-concept study.

Lutz W, Schwartz B, Hofmann SG, Fisher AJ, Husen K, Rubel JA.

Sci Rep. 2018 May 18;8(1):7819. doi: 10.1038/s41598-018-25953-0.


Translating Person-Specific Network Models into Personalized Treatments: Development and Demonstration of the Dynamic Assessment Treatment Algorithm for Individual Networks (DATA-IN).

Rubel JA, Fisher AJ, Husen K, Lutz W.

Psychother Psychosom. 2018 Apr 20. doi: 10.1159/000487769. [Epub ahead of print] No abstract available.


The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity.

Lal NK, Nagalakshmi U, Hurlburt NK, Flores R, Bak A, Sone P, Ma X, Song G, Walley J, Shan L, He P, Casteel C, Fisher AJ, Dinesh-Kumar SP.

Cell Host Microbe. 2018 Apr 11;23(4):485-497.e5. doi: 10.1016/j.chom.2018.03.010.


Lung transplantation for scleroderma lung disease: An international, multicenter, observational cohort study.

Pradère P, Tudorache I, Magnusson J, Savale L, Brugiere O, Douvry B, Reynaud-Gaubert M, Claustre J, Borgne AL, Holm AM, Schultz HH, Knoop C, Godinas L, Fisher AJ, Hirschi S, Gottlieb J, Le Pavec J; Working Group on Heart/Lung Transplantation in Systemic Sclerosis.

J Heart Lung Transplant. 2018 Jul;37(7):903-911. doi: 10.1016/j.healun.2018.03.003. Epub 2018 Mar 15.


α2-6-Neosialidase: A Sialyltransferase Mutant as a Sialyl Linkage-Specific Sialidase.

McArthur JB, Yu H, Tasnima N, Lee CM, Fisher AJ, Chen X.

ACS Chem Biol. 2018 May 18;13(5):1228-1234. doi: 10.1021/acschembio.8b00002. Epub 2018 Mar 28.


Altered DNA methylation is associated with aberrant gene expression in parenchymal but not airway fibroblasts isolated from individuals with COPD.

Clifford RL, Fishbane N, Patel J, MacIsaac JL, McEwen LM, Fisher AJ, Brandsma CA, Nair P, Kobor MS, Hackett TL, Knox AJ.

Clin Epigenetics. 2018 Mar 5;10:32. doi: 10.1186/s13148-018-0464-5. eCollection 2018.


British Thoracic Society Guideline for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD).

Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA.

BMJ Open Respir Res. 2017 Oct 19;4(1):e000242. doi: 10.1136/bmjresp-2017-000242. eCollection 2017. Review.


Potential Mechanisms Underlying TGF-β-mediated Complement Activation in Lung Fibrosis.

Fisher AJ, Cipolla E, Varre A, Gu H, Mickler EA, Vittal R.

Cell Mol Med Open Access. 2017;3(3). pii: 14. Epub 2017 Nov 22.


Pathophysiology and classification of primary graft dysfunction after lung transplantation.

Morrison MI, Pither TL, Fisher AJ.

J Thorac Dis. 2017 Oct;9(10):4084-4097. doi: 10.21037/jtd.2017.09.09. Review.


Controlling miRNA-like off-target effects of an siRNA with nucleobase modifications.

Suter SR, Ball-Jones A, Mumbleau MM, Valenzuela R, Ibarra-Soza J, Owens H, Fisher AJ, Beal PA.

Org Biomol Chem. 2017 Dec 6;15(47):10029-10036. doi: 10.1039/c7ob02654d.


Exploring the idiographic dynamics of mood and anxiety via network analysis.

Fisher AJ, Reeves JW, Lawyer G, Medaglia JD, Rubel JA.

J Abnorm Psychol. 2017 Nov;126(8):1044-1056. doi: 10.1037/abn0000311.


Xeroderma Pigmentosum Group C Deficiency Alters Cigarette Smoke DNA Damage Cell Fate and Accelerates Emphysema Development.

Sears CR, Zhou H, Justice MJ, Fisher AJ, Saliba J, Lamb I, Wicker J, Schweitzer KS, Petrache I.

Am J Respir Cell Mol Biol. 2018 Mar;58(3):402-411. doi: 10.1165/rcmb.2017-0251OC.


British Thoracic Society guidelines for the management of non-tuberculous mycobacterial pulmonary disease (NTM-PD).

Haworth CS, Banks J, Capstick T, Fisher AJ, Gorsuch T, Laurenson IF, Leitch A, Loebinger MR, Milburn HJ, Nightingale M, Ormerod P, Shingadia D, Smith D, Whitehead N, Wilson R, Floto RA.

Thorax. 2017 Nov;72(Suppl 2):ii1-ii64. doi: 10.1136/thoraxjnl-2017-210927. No abstract available.


IL-17A deficiency mitigates bleomycin-induced complement activation during lung fibrosis.

Cipolla E, Fisher AJ, Gu H, Mickler EA, Agarwal M, Wilke CA, Kim KK, Moore BB, Vittal R.

FASEB J. 2017 Dec;31(12):5543-5556. doi: 10.1096/fj.201700289R. Epub 2017 Aug 17.


Report of the ISHLT Working Group on Primary Lung Graft Dysfunction Part III: Mechanisms: A 2016 Consensus Group Statement of the International Society for Heart and Lung Transplantation.

Gelman AE, Fisher AJ, Huang HJ, Baz MA, Shaver CM, Egan TM, Mulligan MS.

J Heart Lung Transplant. 2017 Oct;36(10):1114-1120. doi: 10.1016/j.healun.2017.07.014. Epub 2017 Jul 24. No abstract available.


Development and initial implementation of the Dynamic Assessment Treatment Algorithm (DATA).

Fernandez KC, Fisher AJ, Chi C.

PLoS One. 2017 Jun 27;12(6):e0178806. doi: 10.1371/journal.pone.0178806. eCollection 2017.


Cathepsin K in Lymphangioleiomyomatosis: LAM Cell-Fibroblast Interactions Enhance Protease Activity by Extracellular Acidification.

Dongre A, Clements D, Fisher AJ, Johnson SR.

Am J Pathol. 2017 Aug;187(8):1750-1762. doi: 10.1016/j.ajpath.2017.04.014. Epub 2017 Jun 15.


The role of interleukin-1β as a predictive biomarker and potential therapeutic target during clinical ex vivo lung perfusion.

Andreasson ASI, Borthwick LA, Gillespie C, Jiwa K, Scott J, Henderson P, Mayes J, Romano R, Roman M, Ali S, Fildes JE, Marczin N, Dark JH, Fisher AJ; DEVELOP-UK Investigators.

J Heart Lung Transplant. 2017 Sep;36(9):985-995. doi: 10.1016/j.healun.2017.05.012. Epub 2017 May 12.


Reply to Mohamed S.A. Mohamed.

Andreasson ASI, Dark JH, Fisher AJ.

Eur J Cardiothorac Surg. 2017 Sep 1;52(3):607-608. doi: 10.1093/ejcts/ezx111. No abstract available.


Controlling electronic access to the spin excitations of a single molecule in a tunnel junction.

Warner B, El Hallak F, Prüser H, Ajibade A, Gill TG, Fisher AJ, Persson M, Hirjibehedin CF.

Nanoscale. 2017 Mar 23;9(12):4053-4057. doi: 10.1039/c6nr06469h.


The role of extracorporeal photopheresis in the management of cutaneous T-cell lymphoma, graft-versus-host disease and organ transplant rejection: a consensus statement update from the UK Photopheresis Society.

Alfred A, Taylor PC, Dignan F, El-Ghariani K, Griffin J, Gennery AR, Bonney D, Das-Gupta E, Lawson S, Malladi RK, Douglas KW, Maher T, Guest J, Hartlett L, Fisher AJ, Child F, Scarisbrick JJ.

Br J Haematol. 2017 Apr;177(2):287-310. doi: 10.1111/bjh.14537. Epub 2017 Feb 21.


Survival in portopulmonary hypertension: Outcomes of the United Kingdom National Pulmonary Arterial Hypertension Registry.

Sithamparanathan S, Nair A, Thirugnanasothy L, Coghlan JG, Condliffe R, Dimopoulos K, Elliot CA, Fisher AJ, Gaine S, Gibbs JSR, Gatzoulis MA, E Handler C, Howard LS, Johnson M, Kiely DG, Lordan JL, Peacock AJ, Pepke-Zaba J, Schreiber BE, Sheares KKK, Wort SJ, Corris PA; National Pulmonary Hypertension Service Research Collaboration of the United Kingdom and Ireland.

J Heart Lung Transplant. 2017 Jul;36(7):770-779. doi: 10.1016/j.healun.2016.12.014. Epub 2016 Dec 31.


Comparative Autonomic Responses to Diagnostic Interviewing between Individuals with GAD, MDD, SAD and Healthy Controls.

Diamond AE, Fisher AJ.

Front Hum Neurosci. 2017 Jan 11;10:677. doi: 10.3389/fnhum.2016.00677. eCollection 2016.


Profiling inflammation and tissue injury markers in perfusate and bronchoalveolar lavage fluid during human ex vivo lung perfusion.

Andreasson AS, Karamanou DM, Gillespie CS, Özalp F, Butt T, Hill P, Jiwa K, Walden HR, Green NJ, Borthwick LA, Clark SC, Pauli H, Gould KF, Corris PA, Ali S, Dark JH, Fisher AJ.

Eur J Cardiothorac Surg. 2017 Mar 1;51(3):577-586. doi: 10.1093/ejcts/ezw358.


Interpersonal Problems Predict Differential Response to Cognitive Versus Behavioral Treatment in a Randomized Controlled Trial.

Newman MG, Jacobson NC, Erickson TM, Fisher AJ.

Behav Ther. 2017 Jan;48(1):56-68. doi: 10.1016/j.beth.2016.05.005. Epub 2016 Jun 6.


Effects of Aicardi-Goutières syndrome mutations predicted from ADAR-RNA structures.

Fisher AJ, Beal PA.

RNA Biol. 2017 Feb;14(2):164-170. doi: 10.1080/15476286.2016.1267097. Epub 2016 Dec 12. Review.


Observational Study of Methotrexate in the Treatment of Bronchiolitis Obliterans Syndrome.

Sithamparanathan S, Thirugnanasothy L, Morley KE, Fisher AJ, Lordan JL, Meachery G, Parry G, Corris PA.

Transplant Proc. 2016 Dec;48(10):3387-3392. doi: 10.1016/j.transproceed.2016.09.045.


An association of particulate air pollution and traffic exposure with mortality after lung transplantation in Europe.

Ruttens D, Verleden SE, Bijnens EM, Winckelmans E, Gottlieb J, Warnecke G, Meloni F, Morosini M, Van Der Bij W, Verschuuren EA, Sommerwerck U, Weinreich G, Kamler M, Roman A, Gomez-Olles S, Berastegui C, Benden C, Holm AM, Iversen M, Schultz HH, Luijk B, Oudijk EJ, Kwakkel-van Erp JM, Jaksch P, Klepetko W, Kneidinger N, Neurohr C, Corris P, Fisher AJ, Lordan J, Meachery G, Piloni D, Vandermeulen E, Bellon H, Hoffmann B, Vienneau D, Hoek G, de Hoogh K, Nemery B, Verleden GM, Vos R, Nawrot TS, Vanaudenaerde BM.

Eur Respir J. 2017 Jan 18;49(1). pii: 1600484. doi: 10.1183/13993003.00484-2016. Print 2017 Jan.


Differential responses of positive affect, negative affect, and worry in CBT for generalized anxiety disorder: A person-specific analysis of symptom course during therapy.

Bosley HG, Fisher AJ, Taylor CB.

Psychother Res. 2018 Jul;28(4):630-642. doi: 10.1080/10503307.2016.1233366. Epub 2016 Oct 31.


High-intensity interval training, but not continuous training, reverses right ventricular hypertrophy and dysfunction in a rat model of pulmonary hypertension.

Brown MB, Neves E, Long G, Graber J, Gladish B, Wiseman A, Owens M, Fisher AJ, Presson RG, Petrache I, Kline J, Lahm T.

Am J Physiol Regul Integr Comp Physiol. 2017 Feb 1;312(2):R197-R210. doi: 10.1152/ajpregu.00358.2016. Epub 2016 Oct 26.


Arabidopsis receptor-like cytoplasmic kinase BIK1: purification, crystallization and X-ray diffraction analysis.

Lal NK, Fisher AJ, Dinesh-Kumar SP.

Acta Crystallogr F Struct Biol Commun. 2016 Oct 1;72(Pt 10):738-742. Epub 2016 Sep 22.


Sub-molecular modulation of a 4f driven Kondo resonance by surface-induced asymmetry.

Warner B, El Hallak F, Atodiresei N, Seibt P, Prüser H, Caciuc V, Waters M, Fisher AJ, Blügel S, van Slageren J, Hirjibehedin CF.

Nat Commun. 2016 Sep 26;7:12785. doi: 10.1038/ncomms12785.


A Bayesian hierarchical model for prediction of latent health states from multiple data sources with application to active surveillance of prostate cancer.

Coley RY, Fisher AJ, Mamawala M, Carter HB, Pienta KJ, Zeger SL.

Biometrics. 2017 Jun;73(2):625-634. doi: 10.1111/biom.12577. Epub 2016 Aug 22.


Hypoxia-Inducible Factor-1α Regulates CD55 in Airway Epithelium.

Pandya PH, Fisher AJ, Mickler EA, Temm CJ, Lipking KP, Gracon A, Rothhaar K, Sandusky GE, Murray M, Pollok K, Renbarger J, Blum JS, Lahm T, Wilkes DS.

Am J Respir Cell Mol Biol. 2016 Dec;55(6):889-898.


Observational study of lung transplant recipients surviving 20 years.

Sithamparanathan S, Thirugnanasothy L, Clark S, Dark JH, Fisher AJ, Gould KF, Hasan A, Lordan JL, Meachery G, Parry G, Corris PA.

Respir Med. 2016 Aug;117:103-8. doi: 10.1016/j.rmed.2016.06.008. Epub 2016 Jun 7.


Structural Analysis of an Avr4 Effector Ortholog Offers Insight into Chitin Binding and Recognition by the Cf-4 Receptor.

Kohler AC, Chen LH, Hurlburt N, Salvucci A, Schwessinger B, Fisher AJ, Stergiopoulos I.

Plant Cell. 2016 Aug;28(8):1945-65. doi: 10.1105/tpc.15.00893. Epub 2016 Jul 8.


17β-Estradiol mediates superior adaptation of right ventricular function to acute strenuous exercise in female rats with severe pulmonary hypertension.

Lahm T, Frump AL, Albrecht ME, Fisher AJ, Cook TG, Jones TJ, Yakubov B, Whitson J, Fuchs RK, Liu A, Chesler NC, Brown MB.

Am J Physiol Lung Cell Mol Physiol. 2016 Aug 1;311(2):L375-88. doi: 10.1152/ajplung.00132.2016. Epub 2016 Jun 10.


Telomere Dysfunction and Senescence-associated Pathways in Bronchiectasis.

Birch J, Victorelli S, Rahmatika D, Anderson RK, Jiwa K, Moisey E, Ward C, Fisher AJ, De Soyza A, Passos JF.

Am J Respir Crit Care Med. 2016 Apr 15;193(8):929-32. doi: 10.1164/rccm.201510-2035LE. No abstract available.


Role of CD248 as a potential severity marker in idiopathic pulmonary fibrosis.

Bartis D, Crowley LE, D'Souza VK, Borthwick L, Fisher AJ, Croft AP, Pongrácz JE, Thompson R, Langman G, Buckley CD, Thickett DR.

BMC Pulm Med. 2016 Apr 14;16(1):51. doi: 10.1186/s12890-016-0211-7.


Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity.

Matthews MM, Thomas JM, Zheng Y, Tran K, Phelps KJ, Scott AI, Havel J, Fisher AJ, Beal PA.

Nat Struct Mol Biol. 2016 May;23(5):426-33. doi: 10.1038/nsmb.3203. Epub 2016 Apr 11.


Dynamic RSA: Examining parasympathetic regulatory dynamics via vector-autoregressive modeling of time-varying RSA and heart period.

Fisher AJ, Reeves JW, Chi C.

Psychophysiology. 2016 Jul;53(7):1093-9. doi: 10.1111/psyp.12644. Epub 2016 Apr 4.


Enhancing the Personalization of Psychotherapy With Dynamic Assessment and Modeling.

Fisher AJ, Boswell JF.

Assessment. 2016 Aug;23(4):496-506. doi: 10.1177/1073191116638735.


Contribution of the anaphylatoxin receptors, C3aR and C5aR, to the pathogenesis of pulmonary fibrosis.

Gu H, Fisher AJ, Mickler EA, Duerson F 3rd, Cummings OW, Peters-Golden M, Twigg HL 3rd, Woodruff TM, Wilkes DS, Vittal R.

FASEB J. 2016 Jun;30(6):2336-50. doi: 10.1096/fj.201500044. Epub 2016 Mar 8.


Reductions in the diurnal rigidity of anxiety predict treatment outcome in cognitive behavioral therapy for generalized anxiety disorder.

Fisher AJ, Newman MG.

Behav Res Ther. 2016 Apr;79:46-55. doi: 10.1016/j.brat.2016.02.006. Epub 2016 Feb 27.


Sympathetic and hypothalamic-pituitary-adrenal asymmetry in generalized anxiety disorder.

Reeves JW, Fisher AJ, Newman MG, Granger DA.

Psychophysiology. 2016 Jun;53(6):951-7. doi: 10.1111/psyp.12634. Epub 2016 Mar 2.


Depression is a risk factor for incident coronary heart disease in women: An 18-year longitudinal study.

O'Neil A, Fisher AJ, Kibbey KJ, Jacka FN, Kotowicz MA, Williams LJ, Stuart AL, Berk M, Lewandowski PA, Taylor CB, Pasco JA.

J Affect Disord. 2016 May 15;196:117-24. doi: 10.1016/j.jad.2016.02.029. Epub 2016 Feb 16.


The addition of depression to the Framingham Risk Equation model for predicting coronary heart disease risk in women.

O'Neil A, Fisher AJ, Kibbey KJ, Jacka FN, Kotowicz MA, Williams LJ, Stuart AL, Berk M, Lewandowski PA, Atherton JJ, Taylor CB, Pasco JA.

Prev Med. 2016 Jun;87:115-120. doi: 10.1016/j.ypmed.2016.02.028. Epub 2016 Feb 22.


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