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Items: 37

1.

Extent of MHC Clustering Regulates Selectivity and Effectiveness of T Cell Responses.

Anikeeva N, Fischer NO, Blanchette CD, Sykulev Y.

J Immunol. 2019 Jan 15;202(2):591-597. doi: 10.4049/jimmunol.1801196. Epub 2018 Dec 12.

PMID:
30541879
2.

Evaluation of in vitro neuronal platforms as surrogates for in vivo whole brain systems.

Belle AM, Enright HA, Sales AP, Kulp K, Osburn J, Kuhn EA, Fischer NO, Wheeler EK.

Sci Rep. 2018 Jul 17;8(1):10820. doi: 10.1038/s41598-018-28950-5.

3.

Lipid composition dictates serum stability of reconstituted high-density lipoproteins: implications for in vivo applications.

Gilmore SF, Carpenter TS, Ingólfsson HI, Peters SKG, Henderson PT, Blanchette CD, Fischer NO.

Nanoscale. 2018 Apr 26;10(16):7420-7430. doi: 10.1039/C7NR09690A.

PMID:
29564446
4.

Small-angle X-ray and neutron scattering demonstrates that cell-free expression produces properly formed disc-shaped nanolipoprotein particles.

Cleveland TE 4th, He W, Evans AC, Fischer NO, Lau EY, Coleman MA, Butler P.

Protein Sci. 2018 Mar;27(3):780-789. doi: 10.1002/pro.3365. Epub 2018 Feb 13.

PMID:
29266475
5.

Cell-free production of a functional oligomeric form of a Chlamydia major outer-membrane protein (MOMP) for vaccine development.

He W, Felderman M, Evans AC, Geng J, Homan D, Bourguet F, Fischer NO, Li Y, Lam KS, Noy A, Xing L, Cheng RH, Rasley A, Blanchette CD, Kamrud K, Wang N, Gouvis H, Peterson TC, Hubby B, Coleman MA.

J Biol Chem. 2017 Sep 8;292(36):15121-15132. doi: 10.1074/jbc.M117.784561. Epub 2017 Jul 24.

6.

Enhancement of antigen-specific CD4+ and CD8+ T cell responses using a self-assembled biologic nanolipoprotein particle vaccine.

Weilhammer D, Dunkle AD, Blanchette CD, Fischer NO, Corzett M, Lehmann D, Boone T, Hoeprich P, Driks A, Rasley A.

Vaccine. 2017 Mar 13;35(11):1475-1481. doi: 10.1016/j.vaccine.2017.02.004. Epub 2017 Feb 14.

PMID:
28214044
7.

Lipid Cross-Linking of Nanolipoprotein Particles Substantially Enhances Serum Stability and Cellular Uptake.

Gilmore SF, Blanchette CD, Scharadin TM, Hura GL, Rasley A, Corzett M, Pan CX, Fischer NO, Henderson PT.

ACS Appl Mater Interfaces. 2016 Aug 17;8(32):20549-57. doi: 10.1021/acsami.6b04609. Epub 2016 Aug 4.

8.

Long-term non-invasive interrogation of human dorsal root ganglion neuronal cultures on an integrated microfluidic multielectrode array platform.

Enright HA, Felix SH, Fischer NO, Mukerjee EV, Soscia D, Mcnerney M, Kulp K, Zhang J, Page G, Miller P, Ghetti A, Wheeler EK, Pannu S.

Analyst. 2016 Sep 21;141(18):5346-57. doi: 10.1039/c5an01728a. Epub 2016 Jun 28.

PMID:
27351032
9.

Fluorescence correlation spectroscopy at micromolar concentrations without optical nanoconfinement.

Laurence TA, Ly S, Bourguet F, Fischer NO, Coleman MA.

J Phys Chem B. 2014 Aug 14;118(32):9662-7. doi: 10.1021/jp505881z. Epub 2014 Jul 31.

PMID:
25060197
10.

Nanoparticles and antigen delivery: understanding the benefits and drawbacks of different delivery platforms.

Fischer NO, Rasley A, Blanchette C.

Nanomedicine (Lond). 2014 Apr;9(4):373-6. doi: 10.2217/nnm.14.16. No abstract available.

PMID:
24787434
11.

Enhancing the efficacy of innate immune agonists: could nanolipoprotein particles hold the key?

Fischer NO, Blanchette C, Rasley A.

Nanomedicine (Lond). 2014 Mar;9(3):369-72. doi: 10.2217/nnm.14.15. No abstract available.

PMID:
24746187
12.

Evaluation of nanolipoprotein particles (NLPs) as an in vivo delivery platform.

Fischer NO, Weilhammer DR, Dunkle A, Thomas C, Hwang M, Corzett M, Lychak C, Mayer W, Urbin S, Collette N, Chiun Chang J, Loots GG, Rasley A, Blanchette CD.

PLoS One. 2014 Mar 27;9(3):e93342. doi: 10.1371/journal.pone.0093342. eCollection 2014.

13.

Quantifying interactions of a membrane protein embedded in a lipid nanodisc using fluorescence correlation spectroscopy.

Ly S, Bourguet F, Fischer NO, Lau EY, Coleman MA, Laurence TA.

Biophys J. 2014 Jan 21;106(2):L05-8. doi: 10.1016/j.bpj.2013.12.014.

14.

The use of nanolipoprotein particles to enhance the immunostimulatory properties of innate immune agonists against lethal influenza challenge.

Weilhammer DR, Blanchette CD, Fischer NO, Alam S, Loots GG, Corzett M, Thomas C, Lychak C, Dunkle AD, Ruitenberg JJ, Ghanekar SA, Sant AJ, Rasley A.

Biomaterials. 2013 Dec;34(38):10305-18. doi: 10.1016/j.biomaterials.2013.09.038. Epub 2013 Sep 27.

PMID:
24075406
15.

Nanofiber near-field light-matter interactions for enhanced detection of molecular level displacements and dynamics.

Yoon I, Baker SE, Kim K, Fischer NO, Heineck D, Wang Y, Esener SC, Sirbuly DJ.

Nano Lett. 2013 Apr 10;13(4):1440-5. doi: 10.1021/nl3043085. Epub 2013 Mar 28.

PMID:
23517010
16.

Colocalized delivery of adjuvant and antigen using nanolipoprotein particles enhances the immune response to recombinant antigens.

Fischer NO, Rasley A, Corzett M, Hwang MH, Hoeprich PD, Blanchette CD.

J Am Chem Soc. 2013 Feb 13;135(6):2044-7. doi: 10.1021/ja3063293. Epub 2013 Jan 31.

PMID:
23331082
17.

Enhanced cellulose degradation using cellulase-nanosphere complexes.

Blanchette C, Lacayo CI, Fischer NO, Hwang M, Thelen MP.

PLoS One. 2012;7(8):e42116. doi: 10.1371/journal.pone.0042116. Epub 2012 Aug 1.

18.

Identification and optimization of DNA aptamer binding regions using DNA microarrays.

Fischer NO, Tarasow TM.

Methods Mol Biol. 2011;723:57-66. doi: 10.1007/978-1-61779-043-0_5.

PMID:
21370059
19.

Isolation, characterization, and stability of discretely-sized nanolipoprotein particles assembled with apolipophorin-III.

Fischer NO, Blanchette CD, Segelke BW, Corzett M, Chromy BA, Kuhn EA, Bench G, Hoeprich PD.

PLoS One. 2010 Jul 19;5(7):e11643. doi: 10.1371/journal.pone.0011643.

20.

Kinetic analysis of his-tagged protein binding to nickel-chelating nanolipoprotein particles.

Blanchette CD, Fischer NO, Corzett M, Bench G, Hoeprich PD.

Bioconjug Chem. 2010 Jul 21;21(7):1321-30. doi: 10.1021/bc100129s.

PMID:
20586461
21.

Conjugation to nickel-chelating nanolipoprotein particles increases the potency and efficacy of subunit vaccines to prevent West Nile encephalitis.

Fischer NO, Infante E, Ishikawa T, Blanchette CD, Bourne N, Hoeprich PD, Mason PW.

Bioconjug Chem. 2010 Jun 16;21(6):1018-22. doi: 10.1021/bc100083d.

22.

Hydrogen production by a hyperthermophilic membrane-bound hydrogenase in water-soluble nanolipoprotein particles.

Baker SE, Hopkins RC, Blanchette CD, Walsworth VL, Sumbad R, Fischer NO, Kuhn EA, Coleman M, Chromy BA, Létant SE, Hoeprich PD, Adams MW, Henderson PT.

J Am Chem Soc. 2009 Jun 10;131(22):7508-9. doi: 10.1021/ja809251f.

PMID:
19449869
23.

Immobilization of His-tagged proteins on nickel-chelating nanolipoprotein particles.

Fischer NO, Blanchette CD, Chromy BA, Kuhn EA, Segelke BW, Corzett M, Bench G, Mason PW, Hoeprich PD.

Bioconjug Chem. 2009 Mar 18;20(3):460-5. doi: 10.1021/bc8003155.

PMID:
19239247
24.

Biofunctional subwavelength optical waveguides for biodetection.

Sirbuly DJ, Fischer NO, Huang SC, Artyukhin AB, Tok JB, Bakajin O, Noy A.

ACS Nano. 2008 Feb;2(2):255-62. doi: 10.1021/nn700220b.

PMID:
19206625
25.

Protein-passivated Fe(3)O(4) nanoparticles: low toxicity and rapid heating for thermal therapy.

Samanta B, Yan H, Fischer NO, Shi J, Jerry DJ, Rotello VM.

J Mater Chem. 2008;18(11):1204-1208.

26.

Sensitive and selective viral DNA detection assay via microbead-based rolling circle amplification.

Schopf E, Fischer NO, Chen Y, Tok JB.

Bioorg Med Chem Lett. 2008 Nov 15;18(22):5871-4. doi: 10.1016/j.bmcl.2008.07.064. Epub 2008 Jul 18.

PMID:
18694640
27.

Massively parallel interrogation of aptamer sequence, structure and function.

Fischer NO, Tok JB, Tarasow TM.

PLoS One. 2008 Jul 16;3(7):e2720. doi: 10.1371/journal.pone.0002720.

28.

Single microbead SELEX for efficient ssDNA aptamer generation against botulinum neurotoxin.

Tok JB, Fischer NO.

Chem Commun (Camb). 2008 Apr 28;(16):1883-5. doi: 10.1039/b717936g. Epub 2008 Mar 18.

PMID:
18401506
29.

Protein detection via direct enzymatic amplification of short DNA aptamers.

Fischer NO, Tarasow TM, Tok JB.

Anal Biochem. 2008 Feb 1;373(1):121-8. Epub 2007 Oct 1.

30.

Aptasensors for biosecurity applications.

Fischer NO, Tarasow TM, Tok JB.

Curr Opin Chem Biol. 2007 Jun;11(3):316-28. Epub 2007 Jun 4. Review.

PMID:
17548236
31.

Heightened sense for sensing: recent advances in pathogen immunoassay sensing platforms.

Fischer NO, Tarasow TM, Tok JB.

Analyst. 2007 Mar;132(3):187-91. Epub 2007 Feb 13. Review.

PMID:
17325749
32.

Dual-acting agents that possess free radical scavenging and antithrombotic activities: design, synthesis, and evaluation of phenolic tetrahydro-beta-carboline RGD peptide conjugates.

Bi W, Bi L, Cai J, Liu S, Peng S, Fischer NO, Tok JB, Wang G.

Bioorg Med Chem Lett. 2006 Sep 1;16(17):4523-7. Epub 2006 Jun 23.

PMID:
16797986
33.

Light-induced inhibition of chymotrypsin using photocleavable monolayers on gold nanoparticles.

Fischer NO, Paulini R, Drechsler U, Rotello VM.

Chem Commun (Camb). 2004 Dec 21;(24):2866-7. Epub 2004 Oct 25.

PMID:
15599446
34.

Control of protein structure and function through surface recognition by tailored nanoparticle scaffolds.

Hong R, Fischer NO, Verma A, Goodman CM, Emrick T, Rotello VM.

J Am Chem Soc. 2004 Jan 28;126(3):739-43.

PMID:
14733547
35.

Reversible "irreversible" inhibition of chymotrypsin using nanoparticle receptors.

Fischer NO, Verma A, Goodman CM, Simard JM, Rotello VM.

J Am Chem Soc. 2003 Nov 5;125(44):13387-91.

PMID:
14583034
36.

Inhibition of chymotrypsin through surface binding using nanoparticle-based receptors.

Fischer NO, McIntosh CM, Simard JM, Rotello VM.

Proc Natl Acad Sci U S A. 2002 Apr 16;99(8):5018-23. Epub 2002 Apr 2.

37.

HSV-2 disrupts gap junctional intercellular communication between mammalian cells in vitro.

Fischer NO, Mbuy GN, Woodruff RI.

J Virol Methods. 2001 Feb;91(2):157-66.

PMID:
11164497

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