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Items: 1 to 50 of 67

1.

A Novel Mitochondrial Inhibitor Blocks MAPK Pathway and Overcomes MAPK Inhibitor Resistance in Melanoma.

Vashisht Gopal YN, Gammon S, Prasad R, Knighton B, Pisaneschi F, Roszik J, Feng N, Johnson S, Pramanik S, Sudderth J, Sui D, Hudgens C, Fischer GM, Deng W, Reuben A, Peng W, Wang J, McQuade JL, Tetzlaff MT, Di Francesco ME, Marszalek J, Piwnica-Worms D, DeBerardinis RJ, Davies MA.

Clin Cancer Res. 2019 Aug 22. doi: 10.1158/1078-0432.CCR-19-0836. [Epub ahead of print]

PMID:
31439581
2.

AKT1E17K Activates Focal Adhesion Kinase and Promotes Melanoma Brain Metastasis.

Kircher DA, Trombetti KA, Silvis MR, Parkman GL, Fischer GM, Angel SN, Stehn CM, Strain SC, Grossmann AH, Duffy KL, Boucher KM, McMahon M, Davies MA, Mendoza MC, VanBrocklin MW, Holmen SL.

Mol Cancer Res. 2019 Sep;17(9):1787-1800. doi: 10.1158/1541-7786.MCR-18-1372. Epub 2019 May 28.

PMID:
31138602
3.

Molecular Profiling Reveals Unique Immune and Metabolic Features of Melanoma Brain Metastases.

Fischer GM, Jalali A, Kircher DA, Lee WC, McQuade JL, Haydu LE, Joon AY, Reuben A, de Macedo MP, Carapeto FCL, Yang C, Srivastava A, Ambati CR, Sreekumar A, Hudgens CW, Knighton B, Deng W, Ferguson SD, Tawbi HA, Glitza IC, Gershenwald JE, Vashisht Gopal YN, Hwu P, Huse JT, Wargo JA, Futreal PA, Putluri N, Lazar AJ, DeBerardinis RJ, Marszalek JR, Zhang J, Holmen SL, Tetzlaff MT, Davies MA.

Cancer Discov. 2019 May;9(5):628-645. doi: 10.1158/2159-8290.CD-18-1489. Epub 2019 Feb 20.

PMID:
30787016
4.

Field Investigation of Ambulatory Clinic Exam Room Design with respect to Computing Devices: A Pilot Study.

Saleem JJ, Weiler DT, Satterly T, Nussbaum MA, Chumbler NR, Fischer GM, Rehman SU.

Proc Hum Factors Ergon Soc Annu Meet. 2018 Sep;62(1):518-522. doi: 10.1177/1541931218621118. Epub 2018 Sep 25.

5.

Ambulatory Clinic Exam Room Design with respect to Computing Devices: A Laboratory Simulation Study.

Weiler DT, Satterly T, Rehman SU, Nussbaum MA, Chumbler NR, Fischer GM, Saleem JJ.

IISE Trans Occup Ergon Hum Factors. 2018;6(3-4):165-177. doi: 10.1080/24725838.2018.1456988. Epub 2018 Jun 8.

6.

Metabolic strategies of melanoma cells: Mechanisms, interactions with the tumor microenvironment, and therapeutic implications.

Fischer GM, Vashisht Gopal YN, McQuade JL, Peng W, DeBerardinis RJ, Davies MA.

Pigment Cell Melanoma Res. 2018 Jan;31(1):11-30. doi: 10.1111/pcmr.12661. Epub 2017 Nov 2. Review.

7.

Electronic Delocalization in the Radical Cations of Porphyrin Oligomer Molecular Wires.

Peeks MD, Tait CE, Neuhaus P, Fischer GM, Hoffmann M, Haver R, Cnossen A, Harmer JR, Timmel CR, Anderson HL.

J Am Chem Soc. 2017 Aug 2;139(30):10461-10471. doi: 10.1021/jacs.7b05386. Epub 2017 Jul 24.

8.

Whole-Exome Sequencing Identifies Biallelic IDH3A Variants as a Cause of Retinitis Pigmentosa Accompanied by Pseudocoloboma.

Pierrache LHM, Kimchi A, Ratnapriya R, Roberts L, Astuti GDN, Obolensky A, Beryozkin A, Tjon-Fo-Sang MJH, Schuil J, Klaver CCW, Bongers EMHF, Haer-Wigman L, Schalij N, Breuning MH, Fischer GM, Banin E, Ramesar RS, Swaroop A, van den Born LI, Sharon D, Cremers FPM.

Ophthalmology. 2017 Jul;124(7):992-1003. doi: 10.1016/j.ophtha.2017.03.010. Epub 2017 Apr 13.

9.

Photophysics of aminophenyl substituted pyrrolopyrrole cyanines.

Wiktorowski S, Fischer GM, Winterhalder MJ, Daltrozzo E, Zumbusch A.

Phys Chem Chem Phys. 2012 Feb 28;14(8):2921-8. doi: 10.1039/c2cp23330d. Epub 2012 Jan 19.

PMID:
22262058
10.

Four sensitive screening tools to detect cognitive dysfunction in geriatric emergency department patients: brief Alzheimer's Screen, Short Blessed Test, Ottawa 3DY, and the caregiver-completed AD8.

Carpenter CR, Bassett ER, Fischer GM, Shirshekan J, Galvin JE, Morris JC.

Acad Emerg Med. 2011 Apr;18(4):374-84. doi: 10.1111/j.1553-2712.2011.01040.x.

11.

Selective NIR chromophores: bis(pyrrolopyrrole) cyanines.

Fischer GM, Daltrozzo E, Zumbusch A.

Angew Chem Int Ed Engl. 2011 Feb 7;50(6):1406-9. doi: 10.1002/anie.201004829. Epub 2011 Jan 5. No abstract available.

PMID:
21290523
12.

Noninvasive photoacoustic and fluorescence sentinel lymph node identification using dye-loaded perfluorocarbon nanoparticles.

Akers WJ, Kim C, Berezin M, Guo K, Fuhrhop R, Lanza GM, Fischer GM, Daltrozzo E, Zumbusch A, Cai X, Wang LV, Achilefu S.

ACS Nano. 2011 Jan 25;5(1):173-82. doi: 10.1021/nn102274q. Epub 2010 Dec 20.

13.

Asymmetric PPCys: strongly fluorescing NIR labels.

Fischer GM, Jüngst C, Isomäki-Krondahl M, Gauss D, Möller HM, Daltrozzo E, Zumbusch A.

Chem Commun (Camb). 2010 Aug 7;46(29):5289-91. doi: 10.1039/c0cc00359j. Epub 2010 Jun 11.

PMID:
20539898
14.

Long fluorescence lifetime molecular probes based on near infrared pyrrolopyrrole cyanine fluorophores for in vivo imaging.

Berezin MY, Akers WJ, Guo K, Fischer GM, Daltrozzo E, Zumbusch A, Achilefu S.

Biophys J. 2009 Nov 4;97(9):L22-4. doi: 10.1016/j.bpj.2009.08.022.

15.

Pyrrolopyrrole cyanine dyes: a new class of near-infrared dyes and fluorophores.

Fischer GM, Isomäki-Krondahl M, Göttker-Schnetmann I, Daltrozzo E, Zumbusch A.

Chemistry. 2009;15(19):4857-64. doi: 10.1002/chem.200801996.

PMID:
19296481
16.

Near-infrared dyes and fluorophores based on diketopyrrolopyrroles.

Fischer GM, Ehlers AP, Zumbusch A, Daltrozzo E.

Angew Chem Int Ed Engl. 2007;46(20):3750-3. No abstract available.

PMID:
17410628
17.

The MicroArray Quality Control (MAQC) project shows inter- and intraplatform reproducibility of gene expression measurements.

MAQC Consortium, Shi L, Reid LH, Jones WD, Shippy R, Warrington JA, Baker SC, Collins PJ, de Longueville F, Kawasaki ES, Lee KY, Luo Y, Sun YA, Willey JC, Setterquist RA, Fischer GM, Tong W, Dragan YP, Dix DJ, Frueh FW, Goodsaid FM, Herman D, Jensen RV, Johnson CD, Lobenhofer EK, Puri RK, Schrf U, Thierry-Mieg J, Wang C, Wilson M, Wolber PK, Zhang L, Amur S, Bao W, Barbacioru CC, Lucas AB, Bertholet V, Boysen C, Bromley B, Brown D, Brunner A, Canales R, Cao XM, Cebula TA, Chen JJ, Cheng J, Chu TM, Chudin E, Corson J, Corton JC, Croner LJ, Davies C, Davison TS, Delenstarr G, Deng X, Dorris D, Eklund AC, Fan XH, Fang H, Fulmer-Smentek S, Fuscoe JC, Gallagher K, Ge W, Guo L, Guo X, Hager J, Haje PK, Han J, Han T, Harbottle HC, Harris SC, Hatchwell E, Hauser CA, Hester S, Hong H, Hurban P, Jackson SA, Ji H, Knight CR, Kuo WP, LeClerc JE, Levy S, Li QZ, Liu C, Liu Y, Lombardi MJ, Ma Y, Magnuson SR, Maqsodi B, McDaniel T, Mei N, Myklebost O, Ning B, Novoradovskaya N, Orr MS, Osborn TW, Papallo A, Patterson TA, Perkins RG, Peters EH, Peterson R, Philips KL, Pine PS, Pusztai L, Qian F, Ren H, Rosen M, Rosenzweig BA, Samaha RR, Schena M, Schroth GP, Shchegrova S, Smith DD, Staedtler F, Su Z, Sun H, Szallasi Z, Tezak Z, Thierry-Mieg D, Thompson KL, Tikhonova I, Turpaz Y, Vallanat B, Van C, Walker SJ, Wang SJ, Wang Y, Wolfinger R, Wong A, Wu J, Xiao C, Xie Q, Xu J, Yang W, Zhang L, Zhong S, Zong Y, Slikker W Jr.

Nat Biotechnol. 2006 Sep;24(9):1151-61.

18.

Effect of aromatic ring-containing drugs on carnitine biosynthesis in rats with special regard to p-aminomethylbenzoic acid.

Debreceni B, Farkas V, Fischer GM, Sandor A.

Metabolism. 2005 Dec;54(12):1582-6.

PMID:
16311089
19.

Thermal properties and crystallization dynamics of a phase-change alloy for write-once optical data storage.

Fischer GM, Medower B, Revay R, Mansuripur M.

Appl Opt. 2002 Apr 1;41(10):1998-2007.

PMID:
11936803
20.

Splenic and peritoneal B-1 cells differ in terms of transcriptional and proliferative features that separate peritoneal B-1 from splenic B-2 cells.

Fischer GM, Solt LA, Hastings WD, Yang K, Gerstein RM, Nikolajczyk BS, Clarke SH, Rothstein TL.

Cell Immunol. 2001 Oct 10;213(1):62-71.

PMID:
11747357
21.

STAT3 activation, chemokine receptor expression, and cyclin-Cdk function in B-1 cells.

Rothstein TL, Fischer GM, Tanguay DA, Pavlovic S, Colarusso TP, Gerstein RM, Clarke SH, Chiles TC.

Curr Top Microbiol Immunol. 2000;252:121-30. No abstract available.

PMID:
11125469
22.

Corrigendum to 'Metabolism of carnitine in phenylacetic acid-treated rats and in patients with phenylketonuria'.

Fischer GM, Nemeti B, Farkas V V, Debreceni B, Laszlo A, Schuler A, Somogyi C, Sandor A.

Biochim Biophys Acta. 2000 Nov 15;1502(3):515. No abstract available.

PMID:
11068193
23.

Metabolism of carnitine in phenylacetic acid-treated rats and in patients with phenylketonuria.

Fischer GM, Nemeti B, Farkas V, Debreceni B, Laszlo A, Schaffer Z, Somogyi C, Sandor A.

Biochim Biophys Acta. 2000 Jun 15;1501(2-3):200-10.

24.

Remineralization by fluoride enhanced with calcium and phosphate ingredients.

Schemehorn BR, Orban JC, Wood GD, Fischer GM, Winston AE.

J Clin Dent. 1999;10(1 Spec No):13-6.

PMID:
10686853
25.

Molecular mechanism of the short-term cardiotoxicity caused by 2',3'-dideoxycytidine (ddC): modulation of reactive oxygen species levels and ADP-ribosylation reactions.

Skuta G, Fischer GM, Janaky T, Kele Z, Szabo P, Tozser J, Sumegi B.

Biochem Pharmacol. 1999 Dec 15;58(12):1915-25.

PMID:
10591146
26.

Enhanced ADP-ribosylation and its diminution by lipoamide after ischemia-reperfusion in perfused rat heart.

Szabados E, Fischer GM, Gallyas F Jr, Kispal G, Sumegi B.

Free Radic Biol Med. 1999 Nov;27(9-10):1103-13.

PMID:
10569643
27.

A novel gene coding for a Fas apoptosis inhibitory molecule (FAIM) isolated from inducibly Fas-resistant B lymphocytes.

Schneider TJ, Fischer GM, Donohoe TJ, Colarusso TP, Rothstein TL.

J Exp Med. 1999 Mar 15;189(6):949-56.

28.

Role of reactive oxygen species and poly-ADP-ribose polymerase in the development of AZT-induced cardiomyopathy in rat.

Szabados E, Fischer GM, Toth K, Csete B, Nemeti B, Trombitas K, Habon T, Endrei D, Sumegi B.

Free Radic Biol Med. 1999 Feb;26(3-4):309-17.

PMID:
9895221
29.

Measurement of enamel remineralization using microradiography and confocal microscopy. A correlational study.

González-Cabezas C, Fontana M, Dunipace AJ, Li Y, Fischer GM, Proskin HM, Stookey GK.

Caries Res. 1998;32(5):385-92.

PMID:
9701664
30.

An in situ interproximal model for studying the effect of fluoride on enamel.

Dunipace AJ, Hall AF, Kelly SA, Beiswanger AJ, Fischer GM, Lukantsova LL, Eckert GJ, Stookey GK.

Caries Res. 1997;31(1):60-70.

PMID:
8955997
31.

Intracellular signaling for inducible antigen receptor-mediated Fas resistance in B cells.

Foote LC, Schneider TJ, Fischer GM, Wang JK, Rasmussen B, Campbell KA, Lynch DH, Ju ST, Marshak-Rothstein A, Rothstein TL.

J Immunol. 1996 Sep 1;157(5):1878-85.

PMID:
8757305
32.

Validation and assessment of a conversational interaction intervention.

Hughes C, Killian DJ, Fischer GM.

Am J Ment Retard. 1996 Mar;100(5):493-509.

PMID:
8852301
33.

Inducible resistance to Fas-mediated apoptosis in primary B lymphocytes.

Rothstein TL, Foote LC, Schneider TJ, Fischer GM, Jacobson BA, Lynch DH, Ju ST, Marshak-Rothstein A.

Adv Exp Med Biol. 1996;406:177-89. No abstract available.

PMID:
8910684
34.

Nonlocal response of grain-boundary-type Josephson junctions to local perturbation.

Mayer B, Schulze H, Fischer GM, Gross R.

Phys Rev B Condens Matter. 1995 Sep 1;52(10):7727-7741. No abstract available.

PMID:
9979719
35.

Spatially Resolved Observation of Static Magnetic Flux States in YBa2Cu3O7-dgr Grain Boundary Josephson Junctions.

Fischer GM, Mayer B, Gross R, Nissel T, Husemann KD, Huebener RP, Freltoft T, Shen Y, Vase P.

Science. 1994 Feb 25;263(5150):1112-4.

PMID:
17831622
36.

Amalgam retention using pins, boxes, and Amalgambond.

Fischer GM, Stewart GP, Panelli J.

Am J Dent. 1993 Aug;6(4):173-5.

PMID:
7803002
37.

A three-rooted mandibular second premolar.

Fischer GM, Evans CE.

Gen Dent. 1992 Mar-Apr;40(2):139-40.

PMID:
1499966
38.

A possible mechanism in arterial wall for mediation of sex difference in atherosclerosis.

Fischer GM, Bashey RI, Rosenbaum H, Lyttle CR.

Exp Mol Pathol. 1985 Dec;43(3):288-96.

PMID:
4065308
39.
40.
41.

Hypercholesterolemia in rats: combined effect of high cholesterol diet and female sex steroids.

Fischer GM, Swain ML.

Lipids. 1982 Mar;17(3):172-5. No abstract available.

PMID:
7087694
42.
43.

Influence of contraceptive and other sex steroids on aortic collagen and elastin.

Fischer GM, Swain ML.

Exp Mol Pathol. 1980 Aug;33(1):15-24. No abstract available.

PMID:
7409083
44.

Pulsatile distention and vascular collagen synthesis in the rabbit.

Fischer GM, Swain ML, Cherian K.

Blood Vessels. 1980;17(4):216-20.

PMID:
7397405
46.
47.

Effect of sex hormones on plasma cholesterol in castrated and noncastrated male rats.

Fischer GM, Swain ML.

Experientia. 1978 May 15;34(5):624-5.

PMID:
658247
48.

In vivo effects of sex hormones on aortic elastin and collagen dynamics in castrated and intact male rats.

Fischer GM, Swain ML.

Endocrinology. 1978 Jan;102(1):92-7. No abstract available.

PMID:
743960
49.

Effects of sex hormones on the passive mechanical properties of rat carotid artery.

Cox RH, Fischer GM.

Blood Vessels. 1978;15(4):266-76. No abstract available.

PMID:
638260
50.

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