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Family-wide Annotation of Enzymatic Pathways by Parallel In Vivo Metabolomics.

Kim JT, Li VL, Terrell SM, Fischer CR, Long JZ.

Cell Chem Biol. 2019 Nov 21;26(11):1623-1629.e3. doi: 10.1016/j.chembiol.2019.09.009. Epub 2019 Oct 3.


Preoperative MRI Predictors of Health-Related Quality of Life Improvement after Microscopic Lumbar Discectomy.

Varlotta CG, Manning JH, Ayres EW, Wang E, Woo D, Vasquez-Montes D, Alas H, Brown A, Egers M, Kim Y, Bendo JA, Fischer CR, Protopsaltis TS, Stieber JR, Buckland AJ.

Spine J. 2019 Sep 30. pii: S1529-9430(19)31005-8. doi: 10.1016/j.spinee.2019.09.020. [Epub ahead of print]


CRISPR-Cas9 screens identify regulators of antibody-drug conjugate toxicity.

Tsui CK, Barfield RM, Fischer CR, Morgens DW, Li A, Smith BAH, Gray MA, Bertozzi CR, Rabuka D, Bassik MC.

Nat Chem Biol. 2019 Oct;15(10):949-958. doi: 10.1038/s41589-019-0342-2. Epub 2019 Aug 26.


Minimally Invasive Versus Open Transforaminal Lumbar Interbody Fusion Surgery: An Analysis of Opioids, Nonopioid Analgesics, and Perioperative Characteristics.

Hockley A, Ge D, Vasquez-Montes D, Moawad MA, Passias PG, Errico TJ, Buckland AJ, Protopsaltis TS, Fischer CR.

Global Spine J. 2019 Sep;9(6):624-629. doi: 10.1177/2192568218822320. Epub 2019 Feb 26.


D2O Labeling to Measure Active Biosynthesis of Natural Products in Medicinal Plants.

Nett RS, Guan X, Smith K, Faust AM, Sattely ES, Fischer CR.

AIChE J. 2018 Dec;64(12):4319-4330. doi: 10.1002/aic.16413. Epub 2018 Sep 21.


Factors influencing length of stay following cervical spine surgery: A comparison of myelopathy and radiculopathy patients.

Pierce KE, Gerling MC, Bortz CA, Alas H, Brown AE, Woo D, Vasquez-Montes D, Ayres EW, Diebo BG, Maglaras C, Janjua MB, Buckland AJ, Fischer CR, Protopsaltis TS, Passias PG.

J Clin Neurosci. 2019 Sep;67:109-113. doi: 10.1016/j.jocn.2019.06.009. Epub 2019 Jun 15.


Tunable Enzymatic Synthesis of the Immunomodulator Lipid IVA To Enable Structure-Activity Analysis.

Sankaranarayanan K, Antaris XX, Palanski BA, El Gamal A, Kao CM, Fitch WL, Fischer CR, Khosla C.

J Am Chem Soc. 2019 Jun 19;141(24):9474-9478. doi: 10.1021/jacs.9b03066. Epub 2019 Jun 11.


Total Inpatient Morphine Milligram Equivalents Can Predict Long-term Opioid Use After Transforaminal Lumbar Interbody Fusion.

Ge DH, Hockley A, Vasquez-Montes D, Moawad MA, Passias PG, Errico TJ, Buckland AJ, Protopsaltis TS, Fischer CR.

Spine (Phila Pa 1976). 2019 Oct 15;44(20):1465-1470. doi: 10.1097/BRS.0000000000003106.


Association Between Nonmodifiable Demographic Factors and Patient Satisfaction Scores in Spine Surgery Clinics.

Johnson BC, Vasquez-Montes D, Steinmetz L, Buckland AJ, Bendo JA, Goldstein JA, Errico TJ, Fischer CR.

Orthopedics. 2019 May 1;42(3):143-148. doi: 10.3928/01477447-20190424-05.


Thioesterase-Catalyzed Aminoacylation and Thiolation of Polyketides in Fungi.

Tang MC, Fischer CR, Chari JV, Tan D, Suresh S, Chu A, Miranda M, Smith J, Zhang Z, Garg NK, St Onge RP, Tang Y.

J Am Chem Soc. 2019 May 22;141(20):8198-8206. doi: 10.1021/jacs.9b01083. Epub 2019 May 10.


Instrumentation complication rates following spine surgery: a report from the Scoliosis Research Society (SRS) morbidity and mortality database.

Shillingford JN, Laratta JL, Sarpong NO, Alrabaa RG, Cerpa MK, Lehman RA, Lenke LG, Fischer CR.

J Spine Surg. 2019 Mar;5(1):110-115. doi: 10.21037/jss.2018.12.09.


Osteoporosis Knowledge Among Spine Surgery Patients.

Fischer CR, Vasudeva E, Beaubrun B, Messer Z, Cazzullino A, Lehman R.

Int J Spine Surg. 2018 Dec 21;12(6):689-694. doi: 10.14444/5086. eCollection 2018 Dec.


Evidence Based Medicine Review of Posterior Thoracolumbar Minimally Invasive Technology.

Fischer CR, Beaubrun B, Manning J, Qureshi S, Uribe J.

Int J Spine Surg. 2018 Dec 21;12(6):680-688. doi: 10.14444/5085. eCollection 2018 Dec.


Preoperative Assessment of Bone Quality in Spine Deformity Surgery: Correlation With Clinical Practice and Published Recommendations.

Kuprys TK, Steinmetz LM, Fischer CR, Protopsaltis TS, Passias PG, Goldstein JA, Bendo JA, Errico TJ, Buckland AJ.

Spine (Phila Pa 1976). 2019 Jun 15;44(12):E735-E741. doi: 10.1097/BRS.0000000000002956.


Postoperative Surgical Site Infection After Spine Surgery: An Update From the Scoliosis Research Society (SRS) Morbidity and Mortality Database.

Shillingford JN, Laratta JL, Reddy H, Ha A, Lehman RA Jr, Lenke LG, Fischer CR.

Spine Deform. 2018 Nov - Dec;6(6):634-643. doi: 10.1016/j.jspd.2018.04.004.


Comparative Analysis of Two Transforaminal Lumbar Interbody Fusion Techniques: Open TLIF Versus Wiltse MIS TLIF.

Ge DH, Stekas ND, Varlotta CG, Fischer CR, Petrizzo A, Protopsaltis TS, Passias PG, Errico TJ, Buckland AJ.

Spine (Phila Pa 1976). 2019 May 1;44(9):E555-E560. doi: 10.1097/BRS.0000000000002903.


Utilization of Interspinous Devices Throughout the United States Over a Recent Decade: An Analysis of the Nationwide Inpatient Sample.

Laratta JL, Reddy H, Lombardi JM, Shillingford JN, Saifi C, Fischer CR, Lehman RA Jr, Lenke LG.

Global Spine J. 2018 Jun;8(4):382-387. doi: 10.1177/2192568217731336. Epub 2017 Sep 14.


N-hydroxy-pipecolic acid is a mobile metabolite that induces systemic disease resistance in Arabidopsis.

Chen YC, Holmes EC, Rajniak J, Kim JG, Tang S, Fischer CR, Mudgett MB, Sattely ES.

Proc Natl Acad Sci U S A. 2018 May 22;115(21):E4920-E4929. doi: 10.1073/pnas.1805291115. Epub 2018 May 7.


Optimal Lowest Instrumented Vertebra for Thoracic Adolescent Idiopathic Scoliosis.

Fischer CR, Lenke LG, Bridwell KH, Boachie-Adjei O, Gupta M, Kim YJ.

Spine Deform. 2018 May - Jun;6(3):250-256. doi: 10.1016/j.jspd.2017.10.002.


Complications following single-level interbody fusion procedures: an ACS-NSQIP study.

Shillingford JN, Laratta JL, Lombardi JM, Mueller JD, Cerpa M, Reddy HP, Saifi C, Fischer CR, Lehman RA Jr.

J Spine Surg. 2018 Mar;4(1):17-27. doi: 10.21037/jss.2018.03.19.


HEx: A heterologous expression platform for the discovery of fungal natural products.

Harvey CJB, Tang M, Schlecht U, Horecka J, Fischer CR, Lin HC, Li J, Naughton B, Cherry J, Miranda M, Li YF, Chu AM, Hennessy JR, Vandova GA, Inglis D, Aiyar RS, Steinmetz LM, Davis RW, Medema MH, Sattely E, Khosla C, St Onge RP, Tang Y, Hillenmeyer ME.

Sci Adv. 2018 Apr 11;4(4):eaar5459. doi: 10.1126/sciadv.aar5459. eCollection 2018 Apr.


Visual Loss Following Spine Surgery: What Have We Seen Within the Scoliosis Research Society Morbidity and Mortality Database?

Shillingford JN, Laratta JL, Sarpong NO, Swindell H, Cerpa M, Lehman RA, Lenke LG, Fischer CR.

Spine (Phila Pa 1976). 2018 Sep 1;43(17):1201-1207. doi: 10.1097/BRS.0000000000002592.


The Free-Hand Technique for S2-Alar-Iliac Screw Placement: A Safe and Effective Method for Sacropelvic Fixation in Adult Spinal Deformity.

Shillingford JN, Laratta JL, Tan LA, Sarpong NO, Lin JD, Fischer CR, Lehman RA Jr, Kim YJ, Lenke LG.

J Bone Joint Surg Am. 2018 Feb 21;100(4):334-342. doi: 10.2106/JBJS.17.00052.


Safety of a High-Dose Tranexamic Acid Protocol in Complex Adult Spinal Deformity: Analysis of 100 Consecutive Cases.

Lin JD, Lenke LG, Shillingford JN, Laratta JL, Tan LA, Fischer CR, Weller MA, Lehman RA Jr.

Spine Deform. 2018 Mar - Apr;6(2):189-194. doi: 10.1016/j.jspd.2017.08.007. Epub 2017 Nov 2.


Utilization of vertebroplasty and kyphoplasty procedures throughout the United States over a recent decade: an analysis of the Nationwide Inpatient Sample.

Laratta JL, Shillingford JN, Lombardi JM, Mueller JD, Reddy H, Saifi C, Fischer CR, Ludwig SC, Lenke LG, Lehman RA.

J Spine Surg. 2017 Sep;3(3):364-370. doi: 10.21037/jss.2017.08.02.


Genetic Mapping and Biochemical Basis of Yellow Feather Pigmentation in Budgerigars.

Cooke TF, Fischer CR, Wu P, Jiang TX, Xie KT, Kuo J, Doctorov E, Zehnder A, Khosla C, Chuong CM, Bustamante CD.

Cell. 2017 Oct 5;171(2):427-439.e21. doi: 10.1016/j.cell.2017.08.016.


Calreticulin inhibits inflammation-induced osteoclastogenesis and bone resorption.

Fischer CR, Mikami M, Minematsu H, Nizami S, Goo Lee H, Stamer D, Patel N, Yu Soung D, Back JH, Song L, Drissi H, Lee FY.

J Orthop Res. 2017 Dec;35(12):2658-2666. doi: 10.1002/jor.23587. Epub 2017 Jul 18.


Heterologous expression of diverse propionyl-CoA carboxylases affects polyketide production in Escherichia coli.

Vandova GA, O'Brien RV, Lowry B, Robbins TF, Fischer CR, Davis RW, Khosla C, Harvey CJ, Hillenmeyer ME.

J Antibiot (Tokyo). 2017 Jul;70(7):859-863. doi: 10.1038/ja.2017.38. Epub 2017 Apr 12. No abstract available.


Cost-Effectiveness of Lumbar Spondylolisthesis Surgery at 2-Year Follow-up.

Fischer CR, Cassilly R, Dyrszka M, Trimba Y, Peters A, Goldstein JA, Spivak J, Bendo JA.

Spine Deform. 2016 Jan;4(1):48-54. doi: 10.1016/j.jspd.2015.05.006. Epub 2015 Dec 23.


A Systematic Review of Treatment Strategies for Degenerative Lumbar Spine Fusion Surgery in Patients With Osteoporosis.

Fischer CR, Hanson G, Eller M, Lehman RA.

Geriatr Orthop Surg Rehabil. 2016 Dec;7(4):188-196. Epub 2016 Oct 20.


Tissue engineering advances in spine surgery.

Makhni MC, Caldwell JM, Saifi C, Fischer CR, Lehman RA, Lenke LG, Lee FY.

Regen Med. 2016 Mar;11(2):211-22. doi: 10.2217/rme.16.3. Epub 2016 Feb 15. Review.


Comparative Studies of Three Pairs of α- and γ-Conjugated Folic Acid Derivatives Labeled with Fluorine-18.

Boss SD, Betzel T, Müller C, Fischer CR, Haller S, Reber J, Groehn V, Schibli R, Ametamey SM.

Bioconjug Chem. 2016 Jan 20;27(1):74-86. doi: 10.1021/acs.bioconjchem.5b00644. Epub 2015 Dec 11.


High-throughput platforms for metabolomics.

de Raad M, Fischer CR, Northen TR.

Curr Opin Chem Biol. 2016 Feb;30:7-13. doi: 10.1016/j.cbpa.2015.10.012. Epub 2015 Nov 4. Review.


An accessible, scalable ecosystem for enabling and sharing diverse mass spectrometry imaging analyses.

Fischer CR, Ruebel O, Bowen BP.

Arch Biochem Biophys. 2016 Jan 1;589:18-26. doi: 10.1016/ Epub 2015 Sep 11. Review.


Outcomes and complications of the midline anterior approach 3 years after lumbar spine surgery.

Fischer CR, Braaksma B, Peters A, Weinreb JH, Nalbandian M, Spivak JM, Petrizzo A.

Adv Orthop. 2014;2014:142604. doi: 10.1155/2014/142604. Epub 2014 Dec 22.


Editorial overview: chemical biotechnology: the expansion of chemical biotechnology.

Fischer CR, Schaffer S.

Curr Opin Biotechnol. 2014 Dec;30:v-vii. doi: 10.1016/j.copbio.2014.10.009. Epub 2014 Nov 8. No abstract available.


CA-074Me compound inhibits osteoclastogenesis via suppression of the NFATc1 and c-FOS signaling pathways.

Patel N, Nizami S, Song L, Mikami M, Hsu A, Hickernell T, Chandhanayingyong C, Rho S, Compton JT, Caldwell JM, Kaiser PB, Bai H, Lee HG, Fischer CR, Lee FY.

J Orthop Res. 2015 Oct;33(10):1474-86. doi: 10.1002/jor.22795. Epub 2015 Aug 20.


Factors Predicting Cost-effectiveness of Adult Spinal Deformity Surgery at 2 Years.

Fischer CR, Terran J, Lonner B, McHugh B, Warren D, Glassman S, Bridwell K, Schwab F, Lafage V.

Spine Deform. 2014 Sep;2(5):415-422. doi: 10.1016/j.jspd.2014.04.011. Epub 2014 Aug 27.


Posterior lumbar fusion: choice of approach and adjunct techniques.

Fischer CR, Ducoffe AR, Errico TJ.

J Am Acad Orthop Surg. 2014 Aug;22(8):503-11. doi: 10.5435/JAAOS-22-08-503. Review.


Surgical treatment for adult spinal deformity: projected cost effectiveness at 5-year follow-up.

Terran J, McHugh BJ, Fischer CR, Lonner B, Warren D, Glassman S, Bridwell K, Schwab F, Lafage V.

Ochsner J. 2014 Spring;14(1):14-22.


Imaging atherosclerotic plaque inflammation via folate receptor targeting using a novel 18F-folate radiotracer.

Müller A, Beck K, Rancic Z, Müller C, Fischer CR, Betzel T, Kaufmann PA, Schibli R, Krämer SD, Ametamey SM.

Mol Imaging. 2014;13:1-11.


18 F-click labeling and preclinical evaluation of a new 18 F-folate for PET imaging.

Schieferstein H, Betzel T, Fischer CR, Ross TL.

EJNMMI Res. 2013 Sep 16;3(1):68. doi: 10.1186/2191-219X-3-68.


Assessment of an elastin binding molecule for PET imaging of atherosclerotic plaques.

Fischer CR, Müller A, Bochsler B, Rancic Z, Kaufmann P, Schibli R, Ametamey SM.

Am J Nucl Med Mol Imaging. 2013 Jul 10;3(4):326-35. Print 2013.


Characterization of different osteosarcoma phenotypes by PET imaging in preclinical animal models.

Campanile C, Arlt MJ, Krämer SD, Honer M, Gvozdenovic A, Brennecke P, Fischer CR, Sabile AA, Müller A, Ametamey SM, Born W, Schibli R, Fuchs B.

J Nucl Med. 2013 Aug;54(8):1362-8. doi: 10.2967/jnumed.112.115527. Epub 2013 Jun 25.


Improved PET imaging of tumors in mice using a novel (18) F-folate conjugate with an albumin-binding entity.

Fischer CR, Groehn V, Reber J, Schibli R, Ametamey SM, Müller C.

Mol Imaging Biol. 2013 Dec;15(6):649-54. doi: 10.1007/s11307-013-0651-x.


Stable-isotope probing reveals that hydrogen isotope fractionation in proteins and lipids in a microbial community are different and species-specific.

Fischer CR, Bowen BP, Pan C, Northen TR, Banfield JF.

ACS Chem Biol. 2013 Aug 16;8(8):1755-63. doi: 10.1021/cb400210q. Epub 2013 Jun 5.


A systematic review of comparative studies on bone graft alternatives for common spine fusion procedures.

Fischer CR, Cassilly R, Cantor W, Edusei E, Hammouri Q, Errico T.

Eur Spine J. 2013 Jun;22(6):1423-35. doi: 10.1007/s00586-013-2718-4. Epub 2013 Feb 26. Review.


Radiosynthesis and preclinical evaluation of 3'-Aza-2'-[(18)F]fluorofolic acid: a novel PET radiotracer for folate receptor targeting.

Betzel T, Müller C, Groehn V, Müller A, Reber J, Fischer CR, Krämer SD, Schibli R, Ametamey SM.

Bioconjug Chem. 2013 Feb 20;24(2):205-14. doi: 10.1021/bc300483a. Epub 2013 Jan 17.


Long-term follow-up of shoulder hemiarthroplasty for glenohumeral osteoarthritis.

Levine WN, Fischer CR, Nguyen D, Flatow EL, Ahmad CS, Bigliani LU.

J Bone Joint Surg Am. 2012 Nov 21;94(22):e164. doi: 10.2106/JBJS.K.00603.


[18F]fluoro-deoxy-glucose folate: a novel PET radiotracer with improved in vivo properties for folate receptor targeting.

Fischer CR, Müller C, Reber J, Müller A, Krämer SD, Ametamey SM, Schibli R.

Bioconjug Chem. 2012 Apr 18;23(4):805-13. doi: 10.1021/bc200660z. Epub 2012 Mar 13.


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