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Items: 1 to 50 of 94


C6orf203 is an RNA-binding protein involved in mitochondrial protein synthesis.

Gopalakrishna S, Pearce SF, Dinan AM, Schober FA, Cipullo M, Spåhr H, Khawaja A, Maffezzini C, Freyer C, Wredenberg A, Atanassov I, Firth AE, Rorbach J.

Nucleic Acids Res. 2019 Sep 26;47(17):9386-9399. doi: 10.1093/nar/gkz684.


Comparative Analysis of Gene Expression in Virulent and Attenuated Strains of Infectious Bronchitis Virus at Subcodon Resolution.

Dinan AM, Keep S, Bickerton E, Britton P, Firth AE, Brierley I.

J Virol. 2019 Aug 28;93(18). pii: e00714-19. doi: 10.1128/JVI.00714-19. Print 2019 Sep 15.


Enterovirus Competition Assay to Assess Replication Fitness.

Lulla V, Firth AE.

Bio Protoc. 2019 Jun 3;9(10). doi: 10.21769/BioProtoc.3233. Epub 2019 May 20.


Characterization of the stimulators of protein-directed ribosomal frameshifting in Theiler's murine encephalomyelitis virus.

Napthine S, Bell S, Hill CH, Brierley I, Firth AE.

Nucleic Acids Res. 2019 Sep 5;47(15):8207-8223. doi: 10.1093/nar/gkz503.


Programmed -2/-1 Ribosomal Frameshifting in Simarteriviruses: an Evolutionarily Conserved Mechanism.

Li Y, Firth AE, Brierley I, Cai Y, Napthine S, Wang T, Yan X, Kuhn JH, Fang Y.

J Virol. 2019 Jul 30;93(16). pii: e00370-19. doi: 10.1128/JVI.00370-19. Print 2019 Aug 15.


Retapamulin-Assisted Ribosome Profiling Reveals the Alternative Bacterial Proteome.

Meydan S, Marks J, Klepacki D, Sharma V, Baranov PV, Firth AE, Margus T, Kefi A, Vázquez-Laslop N, Mankin AS.

Mol Cell. 2019 May 2;74(3):481-493.e6. doi: 10.1016/j.molcel.2019.02.017. Epub 2019 Mar 20.


ICTV Virus Taxonomy Profile: Polycipiviridae.

Olendraite I, Brown K, Valles SM, Firth AE, Chen Y, Guérin DMA, Hashimoto Y, Herrero S, de Miranda JR, Ryabov E, Ictv Report Consortium.

J Gen Virol. 2019 Apr;100(4):554-555. doi: 10.1099/jgv.0.001241. Epub 2019 Mar 5.


ICTV Virus Taxonomy Profile: Solinviviridae.

Brown K, Olendraite I, Valles SM, Firth AE, Chen Y, Guérin DMA, Hashimoto Y, Herrero S, de Miranda JR, Ryabov E, Ictv Report Consortium.

J Gen Virol. 2019 May;100(5):736-737. doi: 10.1099/jgv.0.001242. Epub 2019 Mar 5.


Propensity of a picornavirus polymerase to slip on potyvirus-derived transcriptional slippage sites.

Stewart H, Olspert A, Butt BG, Firth AE.

J Gen Virol. 2019 Feb;100(2):199-205. doi: 10.1099/jgv.0.001189. Epub 2018 Dec 3.


An upstream protein-coding region in enteroviruses modulates virus infection in gut epithelial cells.

Lulla V, Dinan AM, Hosmillo M, Chaudhry Y, Sherry L, Irigoyen N, Nayak KM, Stonehouse NJ, Zilbauer M, Goodfellow I, Firth AE.

Nat Microbiol. 2019 Feb;4(2):280-292. doi: 10.1038/s41564-018-0297-1. Epub 2018 Nov 26.


Discovery of a novel Tymoviridae-like virus in mosquitoes from Mexico.

Charles J, Tangudu CS, Hurt SL, Tumescheit C, Firth AE, Garcia-Rejon JE, Machain-Williams C, Blitvich BJ.

Arch Virol. 2019 Feb;164(2):649-652. doi: 10.1007/s00705-018-4098-x. Epub 2018 Nov 13.


Discovery of three RNA viruses using ant transcriptomic datasets.

Kleanthous E, Olendraite I, Lukhovitskaya NI, Firth AE.

Arch Virol. 2019 Feb;164(2):643-647. doi: 10.1007/s00705-018-4093-2. Epub 2018 Nov 10.


Detection of novel and recognized RNA viruses in mosquitoes from the Yucatan Peninsula of Mexico using metagenomics and characterization of their in vitro host ranges.

Charles J, Tangudu CS, Hurt SL, Tumescheit C, Firth AE, Garcia-Rejon JE, Machain-Williams C, Blitvich BJ.

J Gen Virol. 2018 Dec;99(12):1729-1738. doi: 10.1099/jgv.0.001165. Epub 2018 Nov 9.


Transcriptional and Translational Landscape of Equine Torovirus.

Stewart H, Brown K, Dinan AM, Irigoyen N, Snijder EJ, Firth AE.

J Virol. 2018 Aug 16;92(17). pii: e00589-18. doi: 10.1128/JVI.00589-18. Print 2018 Sep 1.


A barnavirus sequence mined from a transcriptome of the Antarctic pearlwort Colobanthus quitensis.

Nibert ML, Manny AR, Debat HJ, Firth AE, Bertini L, Caruso C.

Arch Virol. 2018 Jul;163(7):1921-1926. doi: 10.1007/s00705-018-3794-x. Epub 2018 Mar 7.


Translational autoregulation of BZW1 and BZW2 expression by modulating the stringency of start codon selection.

Loughran G, Firth AE, Atkins JF, Ivanov IP.

PLoS One. 2018 Feb 22;13(2):e0192648. doi: 10.1371/journal.pone.0192648. eCollection 2018.


Ribosome profiling of the retrovirus murine leukemia virus.

Irigoyen N, Dinan AM, Brierley I, Firth AE.

Retrovirology. 2018 Jan 22;15(1):10. doi: 10.1186/s12977-018-0394-5.


Nonstructural proteins nsp2TF and nsp2N of porcine reproductive and respiratory syndrome virus (PRRSV) play important roles in suppressing host innate immune responses.

Li Y, Shang P, Shyu D, Carrillo C, Naraghi-Arani P, Jaing CJ, Renukaradhya GJ, Firth AE, Snijder EJ, Fang Y.

Virology. 2018 Apr;517:164-176. doi: 10.1016/j.virol.2017.12.017. Epub 2018 Jan 8.


ASXL gain-of-function truncation mutants: defective and dysregulated forms of a natural ribosomal frameshifting product?

Dinan AM, Atkins JF, Firth AE.

Biol Direct. 2017 Oct 16;12(1):24. doi: 10.1186/s13062-017-0195-0.


Complete genome sequences of two insect-specific flaviviruses.

Charles J, Tangudu CS, Firth AE, Blitvich BJ.

Arch Virol. 2017 Dec;162(12):3913-3917. doi: 10.1007/s00705-017-3552-5. Epub 2017 Sep 16.


Polycipiviridae: a proposed new family of polycistronic picorna-like RNA viruses.

Olendraite I, Lukhovitskaya NI, Porter SD, Valles SM, Firth AE.

J Gen Virol. 2017 Sep;98(9):2368-2378. doi: 10.1099/jgv.0.000902. Epub 2017 Aug 31.


An analysis by metabolic labelling of the encephalomyocarditis virus ribosomal frameshifting efficiency and stimulators.

Ling R, Firth AE.

J Gen Virol. 2017 Aug;98(8):2100-2105. doi: 10.1099/jgv.0.000888. Epub 2017 Aug 8.


Maturation of selected human mitochondrial tRNAs requires deadenylation.

Pearce SF, Rorbach J, Van Haute L, D'Souza AR, Rebelo-Guiomar P, Powell CA, Brierley I, Firth AE, Minczuk M.

Elife. 2017 Jul 26;6. pii: e27596. doi: 10.7554/eLife.27596.


Translation Initiation from Conserved Non-AUG Codons Provides Additional Layers of Regulation and Coding Capacity.

Ivanov IP, Wei J, Caster SZ, Smith KM, Michel AM, Zhang Y, Firth AE, Freitag M, Dunlap JC, Bell-Pedersen D, Atkins JF, Sachs MS.

MBio. 2017 Jun 27;8(3). pii: e00844-17. doi: 10.1128/mBio.00844-17.


A Review of Flaviviruses that Have No Known Arthropod Vector.

Blitvich BJ, Firth AE.

Viruses. 2017 Jun 21;9(6). pii: E154. doi: 10.3390/v9060154. Review.


Protein-directed ribosomal frameshifting temporally regulates gene expression.

Napthine S, Ling R, Finch LK, Jones JD, Bell S, Brierley I, Firth AE.

Nat Commun. 2017 Jun 8;8:15582. doi: 10.1038/ncomms15582.


Neurodevelopmental protein Musashi-1 interacts with the Zika genome and promotes viral replication.

Chavali PL, Stojic L, Meredith LW, Joseph N, Nahorski MS, Sanford TJ, Sweeney TR, Krishna BA, Hosmillo M, Firth AE, Bayliss R, Marcelis CL, Lindsay S, Goodfellow I, Woods CG, Gergely F.

Science. 2017 Jul 7;357(6346):83-88. doi: 10.1126/science.aam9243. Epub 2017 Jun 1.


Avoidance of reporter assay distortions from fused dual reporters.

Loughran G, Howard MT, Firth AE, Atkins JF.

RNA. 2017 Aug;23(8):1285-1289. doi: 10.1261/rna.061051.117. Epub 2017 Apr 25.


ICTV Virus Taxonomy Profile: Iflaviridae.

Valles SM, Chen Y, Firth AE, Guérin DMA, Hashimoto Y, Herrero S, de Miranda JR, Ryabov E, Ictv Report Consortium.

J Gen Virol. 2017 Apr;98(4):527-528. doi: 10.1099/jgv.0.000757. Epub 2017 Apr 6.


ICTV Virus Taxonomy Profile: Dicistroviridae.

Valles SM, Chen Y, Firth AE, Guérin DMA, Hashimoto Y, Herrero S, de Miranda JR, Ryabov E, Ictv Report Consortium.

J Gen Virol. 2017 Mar;98(3):355-356. doi: 10.1099/jgv.0.000756.


A +1 ribosomal frameshifting motif prevalent among plant amalgaviruses.

Nibert ML, Pyle JD, Firth AE.

Virology. 2016 Nov;498:201-208. doi: 10.1016/j.virol.2016.07.002. Epub 2016 Sep 4.


Ribosomal frameshifting and transcriptional slippage: From genetic steganography and cryptography to adventitious use.

Atkins JF, Loughran G, Bhatt PR, Firth AE, Baranov PV.

Nucleic Acids Res. 2016 Sep 6;44(15):7007-78. doi: 10.1093/nar/gkw530. Epub 2016 Jul 19. Review.


Isolation and characterization of Nylanderia fulva virus 1, a positive-sense, single-stranded RNA virus infecting the tawny crazy ant, Nylanderia fulva.

Valles SM, Oi DH, Becnel JJ, Wetterer JK, LaPolla JS, Firth AE.

Virology. 2016 Sep;496:244-254. doi: 10.1016/j.virol.2016.06.014. Epub 2016 Jun 30.


A novel role for poly(C) binding proteins in programmed ribosomal frameshifting.

Napthine S, Treffers EE, Bell S, Goodfellow I, Fang Y, Firth AE, Snijder EJ, Brierley I.

Nucleic Acids Res. 2016 Jul 8;44(12):5491-503. doi: 10.1093/nar/gkw480. Epub 2016 Jun 2.


Mutational analysis of the Potyviridae transcriptional slippage site utilized for expression of the P3N-PIPO and P1N-PISPO proteins.

Olspert A, Carr JP, Firth AE.

Nucleic Acids Res. 2016 Sep 19;44(16):7618-29. doi: 10.1093/nar/gkw441. Epub 2016 May 16.


High-Resolution Analysis of Coronavirus Gene Expression by RNA Sequencing and Ribosome Profiling.

Irigoyen N, Firth AE, Jones JD, Chung BY, Siddell SG, Brierley I.

PLoS Pathog. 2016 Feb 26;12(2):e1005473. doi: 10.1371/journal.ppat.1005473. eCollection 2016 Feb.


Merida virus, a putative novel rhabdovirus discovered in Culex and Ochlerotatus spp. mosquitoes in the Yucatan Peninsula of Mexico.

Charles J, Firth AE, Loroño-Pino MA, Garcia-Rejon JE, Farfan-Ale JA, Lipkin WI, Blitvich BJ, Briese T.

J Gen Virol. 2016 Apr;97(4):977-87. doi: 10.1099/jgv.0.000424. Epub 2016 Feb 11.


A novel sweet potato potyvirus open reading frame (ORF) is expressed via polymerase slippage and suppresses RNA silencing.

Untiveros M, Olspert A, Artola K, Firth AE, Kreuze JF, Valkonen JP.

Mol Plant Pathol. 2016 Sep;17(7):1111-23. doi: 10.1111/mpp.12366. Epub 2016 Apr 28.


Ecuador Paraiso Escondido Virus, a New Flavivirus Isolated from New World Sand Flies in Ecuador, Is the First Representative of a Novel Clade in the Genus Flavivirus.

Alkan C, Zapata S, Bichaud L, Moureau G, Lemey P, Firth AE, Gritsun TS, Gould EA, de Lamballerie X, Depaquit J, Charrel RN.

J Virol. 2015 Dec;89(23):11773-85. doi: 10.1128/JVI.01543-15. Epub 2015 Sep 9.


The use of duplex-specific nuclease in ribosome profiling and a user-friendly software package for Ribo-seq data analysis.

Chung BY, Hardcastle TJ, Jones JD, Irigoyen N, Firth AE, Baulcombe DC, Brierley I.

RNA. 2015 Oct;21(10):1731-45. doi: 10.1261/rna.052548.115. Epub 2015 Aug 18.


Transcriptional slippage in the positive-sense RNA virus family Potyviridae.

Olspert A, Chung BY, Atkins JF, Carr JP, Firth AE.

EMBO Rep. 2015 Aug;16(8):995-1004. doi: 10.15252/embr.201540509. Epub 2015 Jun 25.


Characterization of Ribosomal Frameshifting in Theiler's Murine Encephalomyelitis Virus.

Finch LK, Ling R, Napthine S, Olspert A, Michiels T, Lardinois C, Bell S, Loughran G, Brierley I, Firth AE.

J Virol. 2015 Aug;89(16):8580-9.


Discovery of a Small Non-AUG-Initiated ORF in Poleroviruses and Luteoviruses That Is Required for Long-Distance Movement.

Smirnova E, Firth AE, Miller WA, Scheidecker D, Brault V, Reinbold C, Rakotondrafara AM, Chung BY, Ziegler-Graff V.

PLoS Pathog. 2015 May 6;11(5):e1004868. doi: 10.1371/journal.ppat.1004868. eCollection 2015 May.


New insights into flavivirus evolution, taxonomy and biogeographic history, extended by analysis of canonical and alternative coding sequences.

Moureau G, Cook S, Lemey P, Nougairede A, Forrester NL, Khasnatinov M, Charrel RN, Firth AE, Gould EA, de Lamballerie X.

PLoS One. 2015 Feb 26;10(2):e0117849. doi: 10.1371/journal.pone.0117849. eCollection 2015.


Mapping overlapping functional elements embedded within the protein-coding regions of RNA viruses.

Firth AE.

Nucleic Acids Res. 2014 Nov 10;42(20):12425-39. doi: 10.1093/nar/gku981. Epub 2014 Oct 17.


Novel flaviviruses from mosquitoes: mosquito-specific evolutionary lineages within the phylogenetic group of mosquito-borne flaviviruses.

Huhtamo E, Cook S, Moureau G, Uzcátegui NY, Sironen T, Kuivanen S, Putkuri N, Kurkela S, Harbach RE, Firth AE, Vapalahti O, Gould EA, de Lamballerie X.

Virology. 2014 Sep;464-465:320-329. doi: 10.1016/j.virol.2014.07.015. Epub 2014 Aug 9.


Solenopsis invicta virus 3: pathogenesis and stage specificity in red imported fire ants.

Valles SM, Porter SD, Firth AE.

Virology. 2014 Jul;460-461:66-71. doi: 10.1016/j.virol.2014.04.026. Epub 2014 May 29.


Analysis of tetra- and hepta-nucleotides motifs promoting -1 ribosomal frameshifting in Escherichia coli.

Sharma V, Prère MF, Canal I, Firth AE, Atkins JF, Baranov PV, Fayet O.

Nucleic Acids Res. 2014 Jun;42(11):7210-25. doi: 10.1093/nar/gku386. Epub 2014 May 29.


Transactivation of programmed ribosomal frameshifting by a viral protein.

Li Y, Treffers EE, Napthine S, Tas A, Zhu L, Sun Z, Bell S, Mark BL, van Veelen PA, van Hemert MJ, Firth AE, Brierley I, Snijder EJ, Fang Y.

Proc Natl Acad Sci U S A. 2014 May 27;111(21):E2172-81. doi: 10.1073/pnas.1321930111. Epub 2014 May 13.

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