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Items: 1 to 50 of 317

1.

Endocrine activities and adipogenic effects of bisphenol AF and its main metabolite.

Skledar DG, Carino A, Trontelj J, Troberg J, Distrutti E, Marchianò S, Tomašič T, Zega A, Finel M, Fiorucci S, Mašič LP.

Chemosphere. 2019 Jan;215:870-880. doi: 10.1016/j.chemosphere.2018.10.129. Epub 2018 Oct 18.

PMID:
30408883
2.

Agonism for the bile acid receptor GPBAR1 reverses liver and vascular damage in a mouse model of steatohepatitis.

Carino A, Marchianò S, Biagioli M, Bucci M, Vellecco V, Brancaleone V, Fiorucci C, Zampella A, Monti MC, Distrutti E, Fiorucci S.

FASEB J. 2018 Oct 10:fj201801373RR. doi: 10.1096/fj.201801373RR. [Epub ahead of print]

PMID:
30303744
3.

Bile Acids Activated Receptors Regulate Innate Immunity.

Fiorucci S, Biagioli M, Zampella A, Distrutti E.

Front Immunol. 2018 Aug 13;9:1853. doi: 10.3389/fimmu.2018.01853. eCollection 2018. Review.

4.

Future trends in the treatment of non-alcoholic steatohepatitis.

Fiorucci S, Biagioli M, Distrutti E.

Pharmacol Res. 2018 Aug;134:289-298. doi: 10.1016/j.phrs.2018.07.014. Epub 2018 Jul 17. Review.

PMID:
30021122
5.

Activation Dynamics of the Neurotensin G Protein-Coupled Receptor 1.

Cong X, Fiorucci S, Golebiowski J.

J Chem Theory Comput. 2018 Aug 14;14(8):4467-4473. doi: 10.1021/acs.jctc.8b00216. Epub 2018 Jul 25.

PMID:
29965755
6.

Farnesoid X receptor modulators 2014-present: a patent review.

Sepe V, Distrutti E, Fiorucci S, Zampella A.

Expert Opin Ther Pat. 2018 May;28(5):351-364. doi: 10.1080/13543776.2018.1459569. Epub 2018 Apr 13. Review.

PMID:
29649907
7.

Agonists of G-Protein-Coupled Odorant Receptors Are Predicted from Chemical Features.

Bushdid C, de March CA, Fiorucci S, Matsunami H, Golebiowski J.

J Phys Chem Lett. 2018 May 3;9(9):2235-2240. doi: 10.1021/acs.jpclett.8b00633. Epub 2018 Apr 17.

PMID:
29648835
8.

Immunephenotype Predicts Response to Vedolizumab: Integrating Clinical and Biochemical Biomarkers in the Treatment of Inflammatory Bowel Diseases.

Fiorucci S, Biagioli M, Distrutti E.

Dig Dis Sci. 2018 Sep;63(9):2168-2171. doi: 10.1007/s10620-018-5039-y. No abstract available.

PMID:
29611077
9.

Disruption of TFGβ-SMAD3 pathway by the nuclear receptor SHP mediates the antifibrotic activities of BAR704, a novel highly selective FXR ligand.

Carino A, Biagioli M, Marchianò S, Scarpelli P, Zampella A, Limongelli V, Fiorucci S.

Pharmacol Res. 2018 May;131:17-31. doi: 10.1016/j.phrs.2018.02.033. Epub 2018 Mar 9.

PMID:
29530598
10.

Genetic and Pharmacological Dissection of the Role of Spleen Tyrosine Kinase (Syk) in Intestinal Inflammation and Immune Dysfunction in Inflammatory Bowel Diseases.

Biagioli M, Mencarelli A, Carino A, Cipriani S, Marchianò S, Fiorucci C, Donini A, Graziosi L, Baldelli F, Distrutti E, Costantino G, Fiorucci S.

Inflamm Bowel Dis. 2017 Dec 19;24(1):123-135. doi: 10.1093/ibd/izx031.

PMID:
29272492
11.

Gpbar1 agonism promotes a Pgc-1α-dependent browning of white adipose tissue and energy expenditure and reverses diet-induced steatohepatitis in mice.

Carino A, Cipriani S, Marchianò S, Biagioli M, Scarpelli P, Zampella A, Monti MC, Fiorucci S.

Sci Rep. 2017 Oct 20;7(1):13689. doi: 10.1038/s41598-017-13102-y.

12.

Metabolic Variability of a Multispecies Probiotic Preparation Impacts on the Anti-inflammatory Activity.

Biagioli M, Laghi L, Carino A, Cipriani S, Distrutti E, Marchianò S, Parolin C, Scarpelli P, Vitali B, Fiorucci S.

Front Pharmacol. 2017 Jul 28;8:505. doi: 10.3389/fphar.2017.00505. eCollection 2017.

13.

Nanotraps with biomimetic surface as decoys for chemokines.

Guryanov I, Cipriani S, Fiorucci S, Zashikhina N, Marchianò S, Scarpelli P, Korzhikov-Vlakh V, Popova E, Korzhikova-Vlakh E, Biondi B, Formaggio F, Tennikova T.

Nanomedicine. 2017 Nov;13(8):2575-2585. doi: 10.1016/j.nano.2017.07.006. Epub 2017 Jul 26.

PMID:
28756094
14.

First Searches for Axions and Axionlike Particles with the LUX Experiment.

Akerib DS, Alsum S, Aquino C, Araújo HM, Bai X, Bailey AJ, Balajthy J, Beltrame P, Bernard EP, Bernstein A, Biesiadzinski TP, Boulton EM, Brás P, Byram D, Cahn SB, Carmona-Benitez MC, Chan C, Chiller AA, Chiller C, Currie A, Cutter JE, Davison TJR, Dobi A, Dobson JEY, Druszkiewicz E, Edwards BN, Faham CH, Fallon SR, Fiorucci S, Gaitskell RJ, Gehman VM, Ghag C, Gibson KR, Gilchriese MGD, Hall CR, Hanhardt M, Haselschwardt SJ, Hertel SA, Hogan DP, Horn M, Huang DQ, Ignarra CM, Jacobsen RG, Ji W, Kamdin K, Kazkaz K, Khaitan D, Knoche R, Larsen NA, Lee C, Lenardo BG, Lesko KT, Lindote A, Lopes MI, Manalaysay A, Mannino RL, Marzioni MF, McKinsey DN, Mei DM, Mock J, Moongweluwan M, Morad JA, Murphy ASJ, Nehrkorn C, Nelson HN, Neves F, O'Sullivan K, Oliver-Mallory KC, Palladino KJ, Pease EK, Reichhart L, Rhyne C, Shaw S, Shutt TA, Silva C, Solmaz M, Solovov VN, Sorensen P, Stephenson S, Sumner TJ, Szydagis M, Taylor DJ, Taylor WC, Tennyson BP, Terman PA, Tiedt DR, To WH, Tripathi M, Tvrznikova L, Uvarov S, Velan V, Verbus JR, Webb RC, White JT, Whitis TJ, Witherell MS, Wolfs FLH, Xu J, Yazdani K, Young SK, Zhang C; LUX Collaboration.

Phys Rev Lett. 2017 Jun 30;118(26):261301. doi: 10.1103/PhysRevLett.118.261301. Epub 2017 Jun 29.

15.

Limits on Spin-Dependent WIMP-Nucleon Cross Section Obtained from the Complete LUX Exposure.

Akerib DS, Alsum S, Araújo HM, Bai X, Bailey AJ, Balajthy J, Beltrame P, Bernard EP, Bernstein A, Biesiadzinski TP, Boulton EM, Brás P, Byram D, Cahn SB, Carmona-Benitez MC, Chan C, Chiller AA, Chiller C, Currie A, Cutter JE, Davison TJR, Dobi A, Dobson JEY, Druszkiewicz E, Edwards BN, Faham CH, Fallon SR, Fiorucci S, Gaitskell RJ, Gehman VM, Ghag C, Gilchriese MGD, Hall CR, Hanhardt M, Haselschwardt SJ, Hertel SA, Hogan DP, Horn M, Huang DQ, Ignarra CM, Jacobsen RG, Ji W, Kamdin K, Kazkaz K, Khaitan D, Knoche R, Larsen NA, Lee C, Lenardo BG, Lesko KT, Lindote A, Lopes MI, Manalaysay A, Mannino RL, Marzioni MF, McKinsey DN, Mei DM, Mock J, Moongweluwan M, Morad JA, Murphy ASJ, Nehrkorn C, Nelson HN, Neves F, O'Sullivan K, Oliver-Mallory KC, Palladino KJ, Pease EK, Reichhart L, Rhyne C, Shaw S, Shutt TA, Silva C, Solmaz M, Solovov VN, Sorensen P, Stephenson S, Sumner TJ, Szydagis M, Taylor DJ, Taylor WC, Tennyson BP, Terman PA, Tiedt DR, To WH, Tripathi M, Tvrznikova L, Uvarov S, Velan V, Verbus JR, Webb RC, White JT, Whitis TJ, Witherell MS, Wolfs FLH, Xu J, Yazdani K, Young SK, Zhang C; LUX Collaboration.

Phys Rev Lett. 2017 Jun 23;118(25):251302. doi: 10.1103/PhysRevLett.118.251302. Epub 2017 Jun 23.

16.

The Bile Acid Receptor GPBAR1 Regulates the M1/M2 Phenotype of Intestinal Macrophages and Activation of GPBAR1 Rescues Mice from Murine Colitis.

Biagioli M, Carino A, Cipriani S, Francisci D, Marchianò S, Scarpelli P, Sorcini D, Zampella A, Fiorucci S.

J Immunol. 2017 Jul 15;199(2):718-733. doi: 10.4049/jimmunol.1700183. Epub 2017 Jun 12.

17.

Update of the ATTRACT force field for the prediction of protein-protein binding affinity.

Chéron JB, Zacharias M, Antonczak S, Fiorucci S.

J Comput Chem. 2017 Jun 5;38(21):1887-1890. doi: 10.1002/jcc.24836. Epub 2017 Jun 5.

PMID:
28580613
18.

Targeting Bile Acid Receptors: Discovery of a Potent and Selective Farnesoid X Receptor Agonist as a New Lead in the Pharmacological Approach to Liver Diseases.

Festa C, De Marino S, Carino A, Sepe V, Marchianò S, Cipriani S, Di Leva FS, Limongelli V, Monti MC, Capolupo A, Distrutti E, Fiorucci S, Zampella A.

Front Pharmacol. 2017 Mar 30;8:162. doi: 10.3389/fphar.2017.00162. eCollection 2017.

19.

Hyodeoxycholic acid derivatives as liver X receptor α and G-protein-coupled bile acid receptor agonists.

De Marino S, Carino A, Masullo D, Finamore C, Marchianò S, Cipriani S, Di Leva FS, Catalanotti B, Novellino E, Limongelli V, Fiorucci S, Zampella A.

Sci Rep. 2017 Feb 24;7:43290. doi: 10.1038/srep43290.

20.

BAR502, a dual FXR and GPBAR1 agonist, promotes browning of white adipose tissue and reverses liver steatosis and fibrosis.

Carino A, Cipriani S, Marchianò S, Biagioli M, Santorelli C, Donini A, Zampella A, Monti MC, Fiorucci S.

Sci Rep. 2017 Feb 16;7:42801. doi: 10.1038/srep42801.

21.

Bornyl-diphosphate synthase from Lavandula angustifolia: A major monoterpene synthase involved in essential oil quality.

Despinasse Y, Fiorucci S, Antonczak S, Moja S, Bony A, Nicolè F, Baudino S, Magnard JL, Jullien F.

Phytochemistry. 2017 May;137:24-33. doi: 10.1016/j.phytochem.2017.01.015. Epub 2017 Feb 9.

PMID:
28190677
22.

Results from a Search for Dark Matter in the Complete LUX Exposure.

Akerib DS, Alsum S, Araújo HM, Bai X, Bailey AJ, Balajthy J, Beltrame P, Bernard EP, Bernstein A, Biesiadzinski TP, Boulton EM, Bramante R, Brás P, Byram D, Cahn SB, Carmona-Benitez MC, Chan C, Chiller AA, Chiller C, Currie A, Cutter JE, Davison TJ, Dobi A, Dobson JE, Druszkiewicz E, Edwards BN, Faham CH, Fiorucci S, Gaitskell RJ, Gehman VM, Ghag C, Gibson KR, Gilchriese MG, Hall CR, Hanhardt M, Haselschwardt SJ, Hertel SA, Hogan DP, Horn M, Huang DQ, Ignarra CM, Ihm M, Jacobsen RG, Ji W, Kamdin K, Kazkaz K, Khaitan D, Knoche R, Larsen NA, Lee C, Lenardo BG, Lesko KT, Lindote A, Lopes MI, Manalaysay A, Mannino RL, Marzioni MF, McKinsey DN, Mei DM, Mock J, Moongweluwan M, Morad JA, Murphy AS, Nehrkorn C, Nelson HN, Neves F, O'Sullivan K, Oliver-Mallory KC, Palladino KJ, Pease EK, Phelps P, Reichhart L, Rhyne C, Shaw S, Shutt TA, Silva C, Solmaz M, Solovov VN, Sorensen P, Stephenson S, Sumner TJ, Szydagis M, Taylor DJ, Taylor WC, Tennyson BP, Terman PA, Tiedt DR, To WH, Tripathi M, Tvrznikova L, Uvarov S, Verbus JR, Webb RC, White JT, Whitis TJ, Witherell MS, Wolfs FL, Xu J, Yazdani K, Young SK, Zhang C; LUX Collaboration.

Phys Rev Lett. 2017 Jan 13;118(2):021303. doi: 10.1103/PhysRevLett.118.021303. Epub 2017 Jan 11.

23.

Decoding the role of the nuclear receptor SHP in regulating hepatic stellate cells and liver fibrogenesis.

Cipriani S, Carino A, Masullo D, Zampella A, Distrutti E, Fiorucci S.

Sci Rep. 2017 Jan 24;7:41055. doi: 10.1038/srep41055.

24.

Sweetness prediction of natural compounds.

Chéron JB, Casciuc I, Golebiowski J, Antonczak S, Fiorucci S.

Food Chem. 2017 Apr 15;221:1421-1425. doi: 10.1016/j.foodchem.2016.10.145. Epub 2016 Nov 3.

PMID:
27979110
25.

The anatomy of mammalian sweet taste receptors.

Chéron JB, Golebiowski J, Antonczak S, Fiorucci S.

Proteins. 2017 Feb;85(2):332-341. doi: 10.1002/prot.25228. Epub 2017 Jan 5.

PMID:
27936499
26.

Decoding the vasoregulatory activities of bile acid-activated receptors in systemic and portal circulation: role of gaseous mediators.

Fiorucci S, Zampella A, Cirino G, Bucci M, Distrutti E.

Am J Physiol Heart Circ Physiol. 2017 Jan 1;312(1):H21-H32. doi: 10.1152/ajpheart.00577.2016. Epub 2016 Oct 7. Review.

27.

Receptor-ligand interactions: Advanced biomedical applications.

Guryanov I, Fiorucci S, Tennikova T.

Mater Sci Eng C Mater Biol Appl. 2016 Nov 1;68:890-903. doi: 10.1016/j.msec.2016.07.072. Epub 2016 Jul 28. Review.

PMID:
27524092
28.

New brominated flame retardants and their metabolites as activators of the pregnane X receptor.

Gramec Skledar D, Tomašič T, Carino A, Distrutti E, Fiorucci S, Peterlin Mašič L.

Toxicol Lett. 2016 Sep 30;259:116-123. doi: 10.1016/j.toxlet.2016.08.005. Epub 2016 Aug 6.

PMID:
27506419
29.

Highly specific blockade of CCR5 inhibits leukocyte trafficking and reduces mucosal inflammation in murine colitis.

Mencarelli A, Cipriani S, Francisci D, Santucci L, Baldelli F, Distrutti E, Fiorucci S.

Sci Rep. 2016 Aug 5;6:30802. doi: 10.1038/srep30802.

30.

Targeting the transsulfuration-H2S pathway by FXR and GPBAR1 ligands in the treatment of portal hypertension.

Fiorucci S, Distrutti E.

Pharmacol Res. 2016 Sep;111:749-756. doi: 10.1016/j.phrs.2016.07.040. Epub 2016 Jul 27. Review.

PMID:
27475883
31.

The bile acid receptor GPBAR1 (TGR5) is expressed in human gastric cancers and promotes epithelial-mesenchymal transition in gastric cancer cell lines.

Carino A, Graziosi L, D'Amore C, Cipriani S, Marchianò S, Marino E, Zampella A, Rende M, Mosci P, Distrutti E, Donini A, Fiorucci S.

Oncotarget. 2016 Sep 20;7(38):61021-61035. doi: 10.18632/oncotarget.10477.

32.

Navigation in bile acid chemical space: discovery of novel FXR and GPBAR1 ligands.

Finamore C, Festa C, Renga B, Sepe V, Carino A, Masullo D, Biagioli M, Marchianò S, Capolupo A, Monti MC, Fiorucci S, Zampella A.

Sci Rep. 2016 Jul 6;6:29320. doi: 10.1038/srep29320.

33.

Phallusiasterol C, A New Disulfated Steroid from the Mediterranean Tunicate Phallusia fumigata.

Imperatore C, Senese M, Aiello A, Luciano P, Fiorucci S, D'Amore C, Carino A, Menna M.

Mar Drugs. 2016 Jun 18;14(6). pii: E117. doi: 10.3390/md14060117.

34.

Results on the Spin-Dependent Scattering of Weakly Interacting Massive Particles on Nucleons from the Run 3 Data of the LUX Experiment.

Akerib DS, Araújo HM, Bai X, Bailey AJ, Balajthy J, Beltrame P, Bernard EP, Bernstein A, Biesiadzinski TP, Boulton EM, Bradley A, Bramante R, Cahn SB, Carmona-Benitez MC, Chan C, Chapman JJ, Chiller AA, Chiller C, Currie A, Cutter JE, Davison TJ, de Viveiros L, Dobi A, Dobson JE, Druszkiewicz E, Edwards BN, Faham CH, Fiorucci S, Gaitskell RJ, Gehman VM, Ghag C, Gibson KR, Gilchriese MG, Hall CR, Hanhardt M, Haselschwardt SJ, Hertel SA, Hogan DP, Horn M, Huang DQ, Ignarra CM, Ihm M, Jacobsen RG, Ji W, Kazkaz K, Khaitan D, Knoche R, Larsen NA, Lee C, Lenardo BG, Lesko KT, Lindote A, Lopes MI, Malling DC, Manalaysay A, Mannino RL, Marzioni MF, McKinsey DN, Mei DM, Mock J, Moongweluwan M, Morad JA, Murphy AS, Nehrkorn C, Nelson HN, Neves F, O'Sullivan K, Oliver-Mallory KC, Ott RA, Palladino KJ, Pangilinan M, Pease EK, Phelps P, Reichhart L, Rhyne C, Shaw S, Shutt TA, Silva C, Solovov VN, Sorensen P, Stephenson S, Sumner TJ, Szydagis M, Taylor DJ, Taylor W, Tennyson BP, Terman PA, Tiedt DR, To WH, Tripathi M, Tvrznikova L, Uvarov S, Verbus JR, Webb RC, White JT, Whitis TJ, Witherell MS, Wolfs FL, Yazdani K, Young SK, Zhang C; LUX Collaboration.

Phys Rev Lett. 2016 Apr 22;116(16):161302. doi: 10.1103/PhysRevLett.116.161302. Epub 2016 Apr 20.

35.

Improved Limits on Scattering of Weakly Interacting Massive Particles from Reanalysis of 2013 LUX Data.

Akerib DS, Araújo HM, Bai X, Bailey AJ, Balajthy J, Beltrame P, Bernard EP, Bernstein A, Biesiadzinski TP, Boulton EM, Bradley A, Bramante R, Cahn SB, Carmona-Benitez MC, Chan C, Chapman JJ, Chiller AA, Chiller C, Currie A, Cutter JE, Davison TJ, de Viveiros L, Dobi A, Dobson JE, Druszkiewicz E, Edwards BN, Faham CH, Fiorucci S, Gaitskell RJ, Gehman VM, Ghag C, Gibson KR, Gilchriese MG, Hall CR, Hanhardt M, Haselschwardt SJ, Hertel SA, Hogan DP, Horn M, Huang DQ, Ignarra CM, Ihm M, Jacobsen RG, Ji W, Kazkaz K, Khaitan D, Knoche R, Larsen NA, Lee C, Lenardo BG, Lesko KT, Lindote A, Lopes MI, Malling DC, Manalaysay A, Mannino RL, Marzioni MF, McKinsey DN, Mei DM, Mock J, Moongweluwan M, Morad JA, Murphy AS, Nehrkorn C, Nelson HN, Neves F, O'Sullivan K, Oliver-Mallory KC, Ott RA, Palladino KJ, Pangilinan M, Pease EK, Phelps P, Reichhart L, Rhyne C, Shaw S, Shutt TA, Silva C, Solovov VN, Sorensen P, Stephenson S, Sumner TJ, Szydagis M, Taylor DJ, Taylor W, Tennyson BP, Terman PA, Tiedt DR, To WH, Tripathi M, Tvrznikova L, Uvarov S, Verbus JR, Webb RC, White JT, Whitis TJ, Witherell MS, Wolfs FL, Yazdani K, Young SK, Zhang C; LUX Collaboration.

Phys Rev Lett. 2016 Apr 22;116(16):161301. doi: 10.1103/PhysRevLett.116.161301. Epub 2016 Apr 20.

36.

Fine-tuning of microsolvation and hydrogen bond interaction regulates substrate channelling in the course of flavonoid biosynthesis.

Diharce J, Golebiowski J, Fiorucci S, Antonczak S.

Phys Chem Chem Phys. 2016 Apr 21;18(15):10337-45. doi: 10.1039/c5cp05059f. Epub 2016 Mar 30.

PMID:
27027108
37.

Gut microbiota role in irritable bowel syndrome: New therapeutic strategies.

Distrutti E, Monaldi L, Ricci P, Fiorucci S.

World J Gastroenterol. 2016 Feb 21;22(7):2219-41. doi: 10.3748/wjg.v22.i7.2219. Review.

38.

Insights on FXR selective modulation. Speculation on bile acid chemical space in the discovery of potent and selective agonists.

Sepe V, Festa C, Renga B, Carino A, Cipriani S, Finamore C, Masullo D, Del Gaudio F, Monti MC, Fiorucci S, Zampella A.

Sci Rep. 2016 Jan 7;6:19008. doi: 10.1038/srep19008.

39.

Investigation on bile acid receptor regulators. Discovery of cholanoic acid derivatives with dual G-protein coupled bile acid receptor 1 (GPBAR1) antagonistic and farnesoid X receptor (FXR) modulatory activity.

Sepe V, Renga B, Festa C, Finamore C, Masullo D, Carino A, Cipriani S, Distrutti E, Fiorucci S, Zampella A.

Steroids. 2016 Jan;105:59-67. doi: 10.1016/j.steroids.2015.11.003. Epub 2015 Dec 1.

PMID:
26607331
40.

Structure-based drug design targeting the cell membrane receptor GPBAR1: exploiting the bile acid scaffold towards selective agonism.

Di Leva FS, Festa C, Renga B, Sepe V, Novellino E, Fiorucci S, Zampella A, Limongelli V.

Sci Rep. 2015 Nov 16;5:16605. doi: 10.1038/srep16605.

41.

Reversal of Endothelial Dysfunction by GPBAR1 Agonism in Portal Hypertension Involves a AKT/FOXOA1 Dependent Regulation of H2S Generation and Endothelin-1.

Renga B, Cipriani S, Carino A, Simonetti M, Zampella A, Fiorucci S.

PLoS One. 2015 Nov 5;10(11):e0141082. doi: 10.1371/journal.pone.0141082. eCollection 2015.

42.

Targeting Integrin-Dependent Adhesion and Signaling with 3-Arylquinoline and 3-Aryl-2-Quinolone Derivatives: A new Class of Integrin Antagonists.

Fiorucci S, Lin X, Sadoul K, Fournet G, Bouvard D, Vinogradova O, Joseph B, Block MR.

PLoS One. 2015 Oct 28;10(10):e0141205. doi: 10.1371/journal.pone.0141205. eCollection 2015.

43.

Bile Acid-Activated Receptors, Intestinal Microbiota, and the Treatment of Metabolic Disorders.

Fiorucci S, Distrutti E.

Trends Mol Med. 2015 Nov;21(11):702-714. doi: 10.1016/j.molmed.2015.09.001. Epub 2015 Oct 16. Review.

PMID:
26481828
44.

The HIV matrix protein p17 induces hepatic lipid accumulation via modulation of nuclear receptor transcriptoma.

Renga B, Francisci D, Carino A, Marchianò S, Cipriani S, Chiara Monti M, Del Sordo R, Schiaroli E, Distrutti E, Baldelli F, Fiorucci S.

Sci Rep. 2015 Oct 15;5:15403. doi: 10.1038/srep15403.

45.

Diethylstilbestrol-scaffold-based pregnane X receptor modulators.

Hodnik Ž, Tomašič T, Smodiš D, D'Amore C, Mašič LP, Fiorucci S, Kikelj D.

Eur J Med Chem. 2015 Oct 20;103:551-62. doi: 10.1016/j.ejmech.2015.09.005. Epub 2015 Sep 8.

PMID:
26408814
46.

Farnesoid X receptor modulators (2011 - 2014): a patent review.

Sepe V, Distrutti E, Fiorucci S, Zampella A.

Expert Opin Ther Pat. 2015;25(8):885-96. doi: 10.1517/13543776.2015.1045413. Review.

PMID:
26183029
47.

Impaired Itching Perception in Murine Models of Cholestasis Is Supported by Dysregulation of GPBAR1 Signaling.

Cipriani S, Renga B, D'Amore C, Simonetti M, De Tursi AA, Carino A, Monti MC, Sepe V, Zampella A, Fiorucci S.

PLoS One. 2015 Jul 15;10(7):e0129866. doi: 10.1371/journal.pone.0129866. eCollection 2015.

48.

Steroidal scaffolds as FXR and GPBAR1 ligands: from chemistry to therapeutical application.

Sepe V, Distrutti E, Limongelli V, Fiorucci S, Zampella A.

Future Med Chem. 2015;7(9):1109-35. doi: 10.4155/fmc.15.54. Review.

PMID:
26132522
49.

Cystathionine γ-lyase, a H2S-generating enzyme, is a GPBAR1-regulated gene and contributes to vasodilation caused by secondary bile acids.

Renga B, Bucci M, Cipriani S, Carino A, Monti MC, Zampella A, Gargiulo A, d'Emmanuele di Villa Bianca R, Distrutti E, Fiorucci S.

Am J Physiol Heart Circ Physiol. 2015 Jul 1;309(1):H114-26. doi: 10.1152/ajpheart.00087.2015. Epub 2015 May 1.

50.

Inhibition of chronic ulcerative colitis-associated adenocarcinoma development in mice by VSL#3.

Talero E, Bolivar S, Ávila-Román J, Alcaide A, Fiorucci S, Motilva V.

Inflamm Bowel Dis. 2015 May;21(5):1027-37. doi: 10.1097/MIB.0000000000000346.

PMID:
25793324

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