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Items: 33


A replication-defective human cytomegalovirus vaccine for prevention of congenital infection.

Wang D, Freed DC, He X, Li F, Tang A, Cox KS, Dubey SA, Cole S, Medi MB, Liu Y, Xu J, Zhang ZQ, Finnefrock AC, Song L, Espeseth AS, Shiver JW, Casimiro DR, Fu TM.

Sci Transl Med. 2016 Oct 26;8(362):362ra145.


Preclinical evaluations of peptide-conjugate vaccines targeting the antigenic domain-2 of glycoprotein B of human cytomegalovirus.

Finnefrock AC, Freed DC, Tang A, Li F, He X, Wu C, Nahas D, Wang D, Fu TM.

Hum Vaccin Immunother. 2016 Aug 2;12(8):2106-2112. Epub 2016 Mar 17.


DNA vaccines targeting heavy chain C-terminal fragments of Clostridium botulinum neurotoxin serotypes A, B, and E induce potent humoral and cellular immunity and provide protection from lethal toxin challenge.

Scott VL, Villarreal DO, Hutnick NA, Walters JN, Ragwan E, Bdeir K, Yan J, Sardesai NY, Finnefrock AC, Casimiro DR, Weiner DB.

Hum Vaccin Immunother. 2015;11(8):1961-71. doi: 10.1080/21645515.2015.1066051.


Development of neutralizing monoclonal antibodies for oncogenic human papillomavirus types 31, 33, 45, 52, and 58.

Brown MJ, Seitz H, Towne V, Müller M, Finnefrock AC.

Clin Vaccine Immunol. 2014 Apr;21(4):587-93. doi: 10.1128/CVI.00773-13. Epub 2014 Feb 26.


Antibodies to a single, conserved epitope in Anopheles APN1 inhibit universal transmission of Plasmodium falciparum and Plasmodium vivax malaria.

Armistead JS, Morlais I, Mathias DK, Jardim JG, Joy J, Fridman A, Finnefrock AC, Bagchi A, Plebanski M, Scorpio DG, Churcher TS, Borg NA, Sattabongkot J, Dinglasan RR.

Infect Immun. 2014 Feb;82(2):818-29. doi: 10.1128/IAI.01222-13. Epub 2013 Dec 9.


Pentameric complex of viral glycoprotein H is the primary target for potent neutralization by a human cytomegalovirus vaccine.

Freed DC, Tang Q, Tang A, Li F, He X, Huang Z, Meng W, Xia L, Finnefrock AC, Durr E, Espeseth AS, Casimiro DR, Zhang N, Shiver JW, Wang D, An Z, Fu TM.

Proc Natl Acad Sci U S A. 2013 Dec 17;110(51):E4997-5005. doi: 10.1073/pnas.1316517110. Epub 2013 Dec 2.


An efficient T-cell epitope discovery strategy using in silico prediction and the iTopia assay platform.

Fridman A, Finnefrock AC, Peruzzi D, Pak I, La Monica N, Bagchi A, Casimiro DR, Ciliberto G, Aurisicchio L.

Oncoimmunology. 2012 Nov 1;1(8):1258-1270.


Pairwise antibody footprinting using surface plasmon resonance technology to characterize human papillomavirus type 16 virus-like particles with direct anti-HPV antibody immobilization.

Towne V, Zhao Q, Brown M, Finnefrock AC.

J Immunol Methods. 2013 Feb 28;388(1-2):1-7. doi: 10.1016/j.jim.2012.11.005. Epub 2012 Nov 15.


Restoration of viral epithelial tropism improves immunogenicity in rabbits and rhesus macaques for a whole virion vaccine of human cytomegalovirus.

Fu TM, Wang D, Freed DC, Tang A, Li F, He X, Cole S, Dubey S, Finnefrock AC, ter Meulen J, Shiver JW, Casimiro DR.

Vaccine. 2012 Dec 14;30(52):7469-74. doi: 10.1016/j.vaccine.2012.10.053. Epub 2012 Oct 26.


Quantitative analysis of neutralizing antibody response to human cytomegalovirus in natural infection.

Wang D, Li F, Freed DC, Finnefrock AC, Tang A, Grimes SN, Casimiro DR, Fu TM.

Vaccine. 2011 Nov 8;29(48):9075-80. doi: 10.1016/j.vaccine.2011.09.056. Epub 2011 Sep 22.


A novel high-throughput neutralization assay for supporting clinical evaluations of human cytomegalovirus vaccines.

Tang A, Li F, Freed DC, Finnefrock AC, Casimiro DR, Wang D, Fu TM.

Vaccine. 2011 Oct 26;29(46):8350-6. doi: 10.1016/j.vaccine.2011.08.086. Epub 2011 Aug 31.


Mapping HIV-1 vaccine induced T-cell responses: bias towards less-conserved regions and potential impact on vaccine efficacy in the Step study.

Li F, Finnefrock AC, Dubey SA, Korber BT, Szinger J, Cole S, McElrath MJ, Shiver JW, Casimiro DR, Corey L, Self SG.

PLoS One. 2011;6(6):e20479. doi: 10.1371/journal.pone.0020479. Epub 2011 Jun 10.


A fully human monoclonal antibody to Staphylococcus aureus iron regulated surface determinant B (IsdB) with functional activity in vitro and in vivo.

Ebert T, Smith S, Pancari G, Clark D, Hampton R, Secore S, Towne V, Fan H, Wang XM, Wu X, Ernst R, Harvey BR, Finnefrock AC, Wang F, Tan C, Durr E, Cope L, Anderson A, An Z, McNeely T.

Hum Antibodies. 2010;19(4):113-28. doi: 10.3233/HAB-2010-0235.


Comparative analysis of immune responses induced by vaccination with SIV antigens by recombinant Ad5 vector or plasmid DNA in rhesus macaques.

Hirao LA, Wu L, Satishchandran A, Khan AS, Draghia-Akli R, Finnefrock AC, Bett AJ, Betts MR, Casimiro DR, Sardesai NY, Kim JJ, Shiver JW, Weiner DB.

Mol Ther. 2010 Aug;18(8):1568-76. doi: 10.1038/mt.2010.112. Epub 2010 Jun 15.


Vaccination with peptide mimetics of the gp41 prehairpin fusion intermediate yields neutralizing antisera against HIV-1 isolates.

Bianchi E, Joyce JG, Miller MD, Finnefrock AC, Liang X, Finotto M, Ingallinella P, McKenna P, Citron M, Ottinger E, Hepler RW, Hrin R, Nahas D, Wu C, Montefiori D, Shiver JW, Pessi A, Kim PS.

Proc Natl Acad Sci U S A. 2010 Jun 8;107(23):10655-60. doi: 10.1073/pnas.1004261107. Epub 2010 May 18.


Affinity maturation and characterization of a human monoclonal antibody against HIV-1 gp41.

Montgomery DL, Wang YJ, Hrin R, Luftig M, Su B, Miller MD, Wang F, Haytko P, Huang L, Vitelli S, Condra J, Liu X, Hampton R, Carfi A, Pessi A, Bianchi E, Joyce J, Lloyd C, Geleziunas R, Bramhill D, King VM, Finnefrock AC, Strohl W, An Z.

MAbs. 2009 Sep-Oct;1(5):462-74. Epub 2009 Sep 8.


Selection and characterization of murine monoclonal antibodies to Staphylococcus aureus iron-regulated surface determinant B with functional activity in vitro and in vivo.

Brown M, Kowalski R, Zorman J, Wang XM, Towne V, Zhao Q, Secore S, Finnefrock AC, Ebert T, Pancari G, Isett K, Zhang Y, Anderson AS, Montgomery D, Cope L, McNeely T.

Clin Vaccine Immunol. 2009 Aug;16(8):1095-104. doi: 10.1128/CVI.00085-09. Epub 2009 Jun 24.


Tolerability of two sequential electroporation treatments using MedPulser DNA delivery system (DDS) in healthy adults.

Wallace M, Evans B, Woods S, Mogg R, Zhang L, Finnefrock AC, Rabussay D, Fons M, Mallee J, Mehrotra D, Schödel F, Musey L.

Mol Ther. 2009 May;17(5):922-8. doi: 10.1038/mt.2009.27. Epub 2009 Mar 10.


PD-1 blockade in rhesus macaques: impact on chronic infection and prophylactic vaccination.

Finnefrock AC, Tang A, Li F, Freed DC, Feng M, Cox KS, Sykes KJ, Guare JP, Miller MD, Olsen DB, Hazuda DJ, Shiver JW, Casimiro DR, Fu TM.

J Immunol. 2009 Jan 15;182(2):980-7.


Enhanced in vivo transgene expression and immunogenicity from plasmid vectors following electrostimulation in rodents and primates.

Simon AJ, Casimiro DR, Finnefrock AC, Davies ME, Tang A, Chen M, Chastain M, Kath GS, Chen L, Shiver JW.

Vaccine. 2008 Sep 19;26(40):5202-9. doi: 10.1016/j.vaccine.2008.03.058. Epub 2008 Apr 14.


Design and optimization of a multiplex anti-influenza peptide immunoassay.

Drummond JE, Shaw EE, Antonello JM, Green T, Page GJ, Motley CO, Wilson KA, Finnefrock AC, Liang X, Casimiro DR.

J Immunol Methods. 2008 May 20;334(1-2):11-20. doi: 10.1016/j.jim.2008.01.017. Epub 2008 Feb 15.


HIV type 1 vaccines for worldwide use: predicting in-clade and cross-clade breadth of immune responses.

Finnefrock AC, Liu X, Opalka DW, Shiver JW, Casimiro DR, Condra JH.

AIDS Res Hum Retroviruses. 2007 Oct;23(10):1283-92.


Fully synthetic carbohydrate HIV antigens designed on the logic of the 2G12 antibody.

Krauss IJ, Joyce JG, Finnefrock AC, Song HC, Dudkin VY, Geng X, Warren JD, Chastain M, Shiver JW, Danishefsky SJ.

J Am Chem Soc. 2007 Sep 12;129(36):11042-4. Epub 2007 Aug 21. No abstract available.


Attenuation of simian immunodeficiency virus SIVmac239 infection by prophylactic immunization with dna and recombinant adenoviral vaccine vectors expressing Gag.

Casimiro DR, Wang F, Schleif WA, Liang X, Zhang ZQ, Tobery TW, Davies ME, McDermott AB, O'Connor DH, Fridman A, Bagchi A, Tussey LG, Bett AJ, Finnefrock AC, Fu TM, Tang A, Wilson KA, Chen M, Perry HC, Heidecker GJ, Freed DC, Carella A, Punt KS, Sykes KJ, Huang L, Ausensi VI, Bachinsky M, Sadasivan-Nair U, Watkins DI, Emini EA, Shiver JW.

J Virol. 2005 Dec;79(24):15547-55.


A human monoclonal antibody neutralizes diverse HIV-1 isolates by binding a critical gp41 epitope.

Miller MD, Geleziunas R, Bianchi E, Lennard S, Hrin R, Zhang H, Lu M, An Z, Ingallinella P, Finotto M, Mattu M, Finnefrock AC, Bramhill D, Cook J, Eckert DM, Hampton R, Patel M, Jarantow S, Joyce J, Ciliberto G, Cortese R, Lu P, Strohl W, Schleif W, McElhaugh M, Lane S, Lloyd C, Lowe D, Osbourn J, Vaughan T, Emini E, Barbato G, Kim PS, Hazuda DJ, Shiver JW, Pessi A.

Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14759-64. Epub 2005 Oct 3.


Vectored Gag and Env but not Tat show efficacy against simian-human immunodeficiency virus 89.6P challenge in Mamu-A*01-negative rhesus monkeys.

Liang X, Casimiro DR, Schleif WA, Wang F, Davies ME, Zhang ZQ, Fu TM, Finnefrock AC, Handt L, Citron MP, Heidecker G, Tang A, Chen M, Wilson KA, Gabryelski L, McElhaugh M, Carella A, Moyer C, Huang L, Vitelli S, Patel D, Lin J, Emini EA, Shiver JW.

J Virol. 2005 Oct;79(19):12321-31.


The plumber's nightmare: a new morphology in block copolymer-ceramic nanocomposites and mesoporous aluminosilicates.

Finnefrock AC, Ulrich R, Toombes GE, Gruner SM, Wiesner U.

J Am Chem Soc. 2003 Oct 29;125(43):13084-93.


Time resolved collapse of a folding protein observed with small angle x-ray scattering.

Pollack L, Tate MW, Finnefrock AC, Kalidas C, Trotter S, Darnton NC, Lurio L, Austin RH, Batt CA, Gruner SM, Mochrie SG.

Phys Rev Lett. 2001 May 21;86(21):4962-5.


Detailed Structure of a Charge-Density Wave in a Quenched Random Field.

Brock JD, Finnefrock AC, Ringland KL, Sweetland E.

Phys Rev Lett. 1994 Dec 26;73(26):3588-3591. No abstract available.


X-ray-scattering measurements of the transient structure of a driven charge-density wave.

Sweetland E, Finnefrock AC, Podulka WJ, Sutton M, Brock JD, DiCarlo D, Thorne RE.

Phys Rev B Condens Matter. 1994 Sep 15;50(12):8157-8165. No abstract available.


Geometric ordering, surface chemistry, band bending, and work function at decapped GaAs(100) surfaces.

Vitomirov IM, Raisanen A, Finnefrock AC, Viturro RE, Brillson LJ, Kirchner PD, Pettit GD, Woodall JM.

Phys Rev B Condens Matter. 1992 Nov 15;46(20):13293-13302. No abstract available.


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