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Items: 1 to 50 of 132


The olfactory G protein-coupled receptor (Olfr-78/OR51E2) modulates the intestinal response to colitis.

Kotlo K, Anbazhagan AN, Priyamvada S, Jayawardena D, Kumar A, Chen Y, Xia Y, Finn PW, Perkins DL, Dudeja PK, Layden BT.

Am J Physiol Cell Physiol. 2020 Mar 1;318(3):C502-C513. doi: 10.1152/ajpcell.00454.2019. Epub 2020 Jan 8.


Declining Pulmonary Function in Interstitial Lung Disease Linked to Lymphocyte Dysfunction.

Schott CA, Ascoli C, Huang Y, Perkins DL, Finn PW.

Am J Respir Crit Care Med. 2020 Mar 1;201(5):610-613. doi: 10.1164/rccm.201910-1909LE. No abstract available.


Cheminformatics in the Identification of Drug Classes for the Treatment of Type 2 Diabetes.

Finn PW.

Methods Mol Biol. 2020;2076:71-84. doi: 10.1007/978-1-4939-9882-1_4.


Ligity: A Non-Superpositional, Knowledge-Based Approach to Virtual Screening.

Ebejer JP, Finn PW, Wong WK, Deane CM, Morris GM.

J Chem Inf Model. 2019 Jun 24;59(6):2600-2616. doi: 10.1021/acs.jcim.8b00779. Epub 2019 Jun 4.


Prenatal Maternal Depression and Neonatal Immune Responses.

Hahn J, Gold DR, Coull BA, McCormick MC, Finn PW, Perkins DL, Rich-Edwards JW, Rifas Shiman SL, Oken E, Kubzansky LD.

Psychosom Med. 2019 May;81(4):320-327. doi: 10.1097/PSY.0000000000000686.


Serotonin Transporter Deficiency is Associated with Dysbiosis and Changes in Metabolic Function of the Mouse Intestinal Microbiome.

Singhal M, Turturice BA, Manzella CR, Ranjan R, Metwally AA, Theorell J, Huang Y, Alrefai WA, Dudeja PK, Finn PW, Perkins DL, Gill RK.

Sci Rep. 2019 Feb 14;9(1):2138. doi: 10.1038/s41598-019-38489-8.


Utilizing longitudinal microbiome taxonomic profiles to predict food allergy via Long Short-Term Memory networks.

Metwally AA, Yu PS, Reiman D, Dai Y, Finn PW, Perkins DL.

PLoS Comput Biol. 2019 Feb 4;15(2):e1006693. doi: 10.1371/journal.pcbi.1006693. eCollection 2019 Feb.


Multiomic Strategies Reveal Diversity and Important Functional Aspects of Human Gut Microbiome.

Ranjan R, Rani A, Finn PW, Perkins DL.

Biomed Res Int. 2018 Nov 14;2018:6074918. doi: 10.1155/2018/6074918. eCollection 2018.


In vitro antioxidant activities of Rhodobacter sphaeroides and protective effect on Caco-2 cell line model.

An J, Yang C, Li Z, Finn PW, Perkins DL, Sun J, Bai Z, Gao L, Zhang M, Ren D.

Appl Microbiol Biotechnol. 2019 Jan;103(2):917-927. doi: 10.1007/s00253-018-9497-0. Epub 2018 Nov 12.


An optimized protocol to quantify signaling in human transitional B cells by phospho flow cytometry.

Zwang NA, Ganesh BB, Cardenas KT, Chong AS, Finn PW, Perkins DL.

J Immunol Methods. 2018 Dec;463:112-121. doi: 10.1016/j.jim.2018.10.002. Epub 2018 Oct 13.


Lower perinatal exposure to Proteobacteria is an independent predictor of early childhood wheezing.

Turturice BA, Gold DR, Litonjua AA, Oken E, Rifas-Shiman S, Perkins DL, Finn PW.

J Allergy Clin Immunol. 2019 Jan;143(1):419-421.e5. doi: 10.1016/j.jaci.2018.06.051. Epub 2018 Sep 8. No abstract available.


Developing Faculty in Emerging Areas of Interdisciplinary Research.

Coleman DL, Tannock LR, Pignone M, Amin AN, Finn PW.

Am J Med. 2018 Oct;131(10):1257-1262. doi: 10.1016/j.amjmed.2018.06.009. Epub 2018 Jul 5.


Bronchiolitis obliterans syndrome susceptibility and the pulmonary microbiome.

Schott C, Weigt SS, Turturice BA, Metwally A, Belperio J, Finn PW, Perkins DL.

J Heart Lung Transplant. 2018 Sep;37(9):1131-1140. doi: 10.1016/j.healun.2018.04.007. Epub 2018 Apr 26.


N-Leucinyl Benzenesulfonamides as Structurally Simplified Leucyl-tRNA Synthetase Inhibitors.

Charlton MH, Aleksis R, Saint-Leger A, Gupta A, Loza E, Ribas de Pouplana L, Kaula I, Gustina D, Madre M, Lola D, Jaudzems K, Edmund G, Randall CP, Kime L, O'Neill AJ, Goessens W, Jirgensons A, Finn PW.

ACS Med Chem Lett. 2018 Jan 18;9(2):84-88. doi: 10.1021/acsmedchemlett.7b00374. eCollection 2018 Feb 8.


MetaLonDA: a flexible R package for identifying time intervals of differentially abundant features in metagenomic longitudinal studies.

Metwally AA, Yang J, Ascoli C, Dai Y, Finn PW, Perkins DL.

Microbiome. 2018 Feb 13;6(1):32. doi: 10.1186/s40168-018-0402-y.


Donor and Recipient Ethnicity Impacts Renal Graft Adverse Outcomes.

Kwan JM, Hajjiri Z, Chen YF, Metwally A, Perkins DL, Finn PW.

J Racial Ethn Health Disparities. 2018 Oct;5(5):1003-1013. doi: 10.1007/s40615-017-0447-9. Epub 2017 Dec 21.


Atopic asthmatic immune phenotypes associated with airway microbiota and airway obstruction.

Turturice BA, McGee HS, Oliver B, Baraket M, Nguyen BT, Ascoli C, Ranjan R, Rani A, Perkins DL, Finn PW.

PLoS One. 2017 Oct 20;12(10):e0184566. doi: 10.1371/journal.pone.0184566. eCollection 2017.


A Circulating Micro-RNA Signature Serves as a Diagnostic and Prognostic Indicator in Sarcoidosis.

Ascoli C, Huang Y, Schott C, Turturice BA, Metwally A, Perkins DL, Finn PW; ACCESS Research Group .

Am J Respir Cell Mol Biol. 2017 Aug 16. doi: 10.1165/rcmb.2017-0207OC. [Epub ahead of print]


The Potential for Emerging Microbiome-Mediated Therapeutics in Asthma.

Ozturk AB, Turturice BA, Perkins DL, Finn PW.

Curr Allergy Asthma Rep. 2017 Aug 10;17(9):62. doi: 10.1007/s11882-017-0730-1. Review.


Perinatal Bacterial Exposure Contributes to IL-13 Aeroallergen Response.

Turturice BA, Ranjan R, Nguyen B, Hughes LM, Andropolis KE, Gold DR, Litonjua AA, Oken E, Perkins DL, Finn PW.

Am J Respir Cell Mol Biol. 2017 Oct;57(4):419-427. doi: 10.1165/rcmb.2017-0027OC.


Complete Genome Sequence of BK Polyomavirus Subtype Ib-1 Detected in a Kidney Transplant Patient with BK Viremia Using Shotgun Sequencing.

Ranjan R, Rani A, Brennan DC, Finn PW, Perkins DL.

Genome Announc. 2017 Feb 9;5(6). pii: e01474-16. doi: 10.1128/genomeA.01474-16.


Effect of the Obesity Epidemic on Kidney Transplantation: Obesity Is Independent of Diabetes as a Risk Factor for Adverse Renal Transplant Outcomes.

Kwan JM, Hajjiri Z, Metwally A, Finn PW, Perkins DL.

PLoS One. 2016 Nov 16;11(11):e0165712. doi: 10.1371/journal.pone.0165712. eCollection 2016.


WEVOTE: Weighted Voting Taxonomic Identification Method of Microbial Sequences.

Metwally AA, Dai Y, Finn PW, Perkins DL.

PLoS One. 2016 Sep 28;11(9):e0163527. doi: 10.1371/journal.pone.0163527. eCollection 2016.


Urinary microbiome of kidney transplant patients reveals dysbiosis with potential for antibiotic resistance.

Rani A, Ranjan R, McGee HS, Andropolis KE, Panchal DV, Hajjiri Z, Brennan DC, Finn PW, Perkins DL.

Transl Res. 2017 Mar;181:59-70. doi: 10.1016/j.trsl.2016.08.008. Epub 2016 Sep 9.


A diverse virome in kidney transplant patients contains multiple viral subtypes with distinct polymorphisms.

Rani A, Ranjan R, McGee HS, Metwally A, Hajjiri Z, Brennan DC, Finn PW, Perkins DL.

Sci Rep. 2016 Sep 16;6:33327. doi: 10.1038/srep33327.


Structure-guided selection of specificity determining positions in the human Kinome.

Moll M, Finn PW, Kavraki LE.

BMC Genomics. 2016 Aug 18;17 Suppl 4:431. doi: 10.1186/s12864-016-2790-3.


Choosing and succeeding in academic medicine: advice for students, trainees, and junior faculty.

Lora CM, Finn PW.

Transl Res. 2016 Nov;177:1-5. doi: 10.1016/j.trsl.2016.06.004. Epub 2016 Jun 16. No abstract available.


Are the physicochemical properties of antibacterial compounds really different from other drugs?

Ebejer JP, Charlton MH, Finn PW.

J Cheminform. 2016 Jun 3;8:30. doi: 10.1186/s13321-016-0143-5. eCollection 2016.


Looking to the Future. Equality in Health and Marriage.

Finn PW.

Ann Am Thorac Soc. 2016 Mar;13(3):305-6. doi: 10.1513/AnnalsATS.201601-005ED. No abstract available.


Precision Subtypes of T Cell-Mediated Rejection Identified by Molecular Profiles.

Kadota PO, Hajjiri Z, Finn PW, Perkins DL.

Front Immunol. 2015 Nov 6;6:536. doi: 10.3389/fimmu.2015.00536. eCollection 2015.


Health equality for pulmonary, critical care, and sleep medicine: opportunities for professional societies.

Finn PW, Malhotra A.

Glob Heart. 2014 Sep;9(3):359-60. doi: 10.1016/j.gheart.2014.07.004. Epub 2014 Oct 31. No abstract available.


Approaches to achieving equality in respiratory health.

Finn PW, Cohen R; Forum of International Respiratory Societies working group collaboration.

Lancet Respir Med. 2015 Feb;3(2):97-98. doi: 10.1016/S2213-2600(14)70247-4. Epub 2014 Nov 12. No abstract available.


Exploration of piperidinols as potential antitubercular agents.

Abuhammad A, Fullam E, Bhakta S, Russell AJ, Morris GM, Finn PW, Sim E.

Molecules. 2014 Oct 10;19(10):16274-90. doi: 10.3390/molecules191016274.


CD45 ligation expands Tregs by promoting interactions with DCs.

Camirand G, Wang Y, Lu Y, Wan YY, Lin Y, Deng S, Guz G, Perkins DL, Finn PW, Farber DL, Flavell RA, Shlomchik WD, Lakkis FG, Rudd CE, Rothstein DM.

J Clin Invest. 2014 Oct;124(10):4603-13. doi: 10.1172/JCI74087. Epub 2014 Sep 9.


The cloud and other new computational methods to improve molecular modelling.

Korb O, Finn PW, Jones G.

Expert Opin Drug Discov. 2014 Oct;9(10):1121-31. doi: 10.1517/17460441.2014.941800. Epub 2014 Aug 22. Review.


Substrate derived peptidic α-ketoamides as inhibitors of the malarial protease PfSUB1.

Kher SS, Penzo M, Fulle S, Finn PW, Blackman MJ, Jirgensons A.

Bioorg Med Chem Lett. 2014 Sep 15;24(18):4486-4489. doi: 10.1016/j.bmcl.2014.07.086. Epub 2014 Aug 7.


Reranking docking poses using molecular simulations and approximate free energy methods.

Lauro G, Ferruz N, Fulle S, Harvey MJ, Finn PW, De Fabritiis G.

J Chem Inf Model. 2014 Aug 25;54(8):2185-9. doi: 10.1021/ci500309a. Epub 2014 Jul 31.


Next generation: community, advocacy.

Finn PW.

Ann Am Thorac Soc. 2014 May;11(4):592-3. doi: 10.1513/AnnalsATS.201403-119ED. No abstract available.


The lung corps' approach to reducing health disparities in respiratory disease.

Thakur N, McGarry ME, Oh SS, Galanter JM, Finn PW, Burchard EG; ATS Health Equality Committee.

Ann Am Thorac Soc. 2014 May;11(4):655-60. doi: 10.1513/AnnalsATS.201402-061AR.


T cells and lung injury. Impact of rapamycin.

Nakajima T, Lin KW, Li J, McGee HS, Kwan JM, Perkins DL, Finn PW.

Am J Respir Cell Mol Biol. 2014 Aug;51(2):294-9. doi: 10.1165/rcmb.2013-0171OC.


Rituximab in the treatment of refractory pulmonary sarcoidosis.

Sweiss NJ, Lower EE, Mirsaeidi M, Dudek S, Garcia JG, Perkins D, Finn PW, Baughman RP.

Eur Respir J. 2014 May;43(5):1525-8. doi: 10.1183/09031936.00224513. Epub 2014 Jan 31. No abstract available.


An official American Thoracic Society/European Respiratory Society policy statement: disparities in respiratory health.

Schraufnagel DE, Blasi F, Kraft M, Gaga M, Finn PW, Rabe KF; ATS/ERS Committee on Disparities in Respiratory Health.

Am J Respir Crit Care Med. 2013 Oct 1;188(7):865-71. doi: 10.1164/rccm.201308-1509ST.


The emerging role of cloud computing in molecular modelling.

Ebejer JP, Fulle S, Morris GM, Finn PW.

J Mol Graph Model. 2013 Jul;44:177-87. doi: 10.1016/j.jmgm.2013.06.002. Epub 2013 Jun 17. Review.


Comparison of ultra-fast 2D and 3D ligand and target descriptors for side effect prediction and network analysis in polypharmacology.

Cortés-Cabrera A, Morris GM, Finn PW, Morreale A, Gago F.

Br J Pharmacol. 2013 Oct;170(3):557-67. doi: 10.1111/bph.12294.


Combinatorial clustering of residue position subsets predicts inhibitor affinity across the human kinome.

Bryant DH, Moll M, Finn PW, Kavraki LE.

PLoS Comput Biol. 2013;9(6):e1003087. doi: 10.1371/journal.pcbi.1003087. Epub 2013 Jun 6.


Molecular determinants of binding to the Plasmodium subtilisin-like protease 1.

Fulle S, Withers-Martinez C, Blackman MJ, Morris GM, Finn PW.

J Chem Inf Model. 2013 Mar 25;53(3):573-83. doi: 10.1021/ci300581z. Epub 2013 Mar 4.


Regulation of cytotoxic T lymphocyte antigen 4 by cyclic AMP.

Li J, Lin KW, Murray F, Nakajima T, Zhao Y, Perkins DL, Finn PW.

Am J Respir Cell Mol Biol. 2013 Jan;48(1):63-70. doi: 10.1165/rcmb.2012-0155OC. Epub 2012 Sep 28.


The public health benefits of air pollution control.

Li J, Ewart G, Kraft M, Finn PW.

J Allergy Clin Immunol. 2012 Jul;130(1):22-3. doi: 10.1016/j.jaci.2012.02.047. Epub 2012 Apr 21. No abstract available.


Systems biology approach to transplant tolerance: proof of concept experiments using RNA interference (RNAi) to knock down hub genes in Jurkat and HeLa cells in vitro.

Lwin WW, Park K, Wauson M, Gao Q, Finn PW, Perkins D, Khanna A.

J Surg Res. 2012 Jul;176(1):e41-6. doi: 10.1016/j.jss.2011.12.002. Epub 2011 Dec 22.


Improving the accuracy of ultrafast ligand-based screening: incorporating lipophilicity into ElectroShape as an extra dimension.

Armstrong MS, Finn PW, Morris GM, Richards WG.

J Comput Aided Mol Des. 2011 Aug;25(8):785-90. doi: 10.1007/s10822-011-9463-8. Epub 2011 Aug 6.


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