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Items: 26

1.

Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs.

Cornacchia D, Zhang C, Zimmer B, Chung SY, Fan Y, Soliman MA, Tchieu J, Chambers SM, Shah H, Paull D, Konrad C, Vincendeau M, Noggle SA, Manfredi G, Finley LWS, Cross JR, Betel D, Studer L.

Cell Stem Cell. 2019 May 21. pii: S1934-5909(19)30205-X. doi: 10.1016/j.stem.2019.05.001. [Epub ahead of print]

PMID:
31155483
2.

Flura-seq identifies organ-specific metabolic adaptations during early metastatic colonization.

Basnet H, Tian L, Ganesh K, Huang YH, Macalinao DG, Brogi E, Finley LW, Massagué J.

Elife. 2019 Mar 26;8. pii: e43627. doi: 10.7554/eLife.43627.

3.

Isoform Switching as a Mechanism of Acquired Resistance to Mutant Isocitrate Dehydrogenase Inhibition.

Harding JJ, Lowery MA, Shih AH, Schvartzman JM, Hou S, Famulare C, Patel M, Roshal M, Do RK, Zehir A, You D, Selcuklu SD, Viale A, Tallman MS, Hyman DM, Reznik E, Finley LWS, Papaemmanuil E, Tosolini A, Frattini MG, MacBeth KJ, Liu G, Fan B, Choe S, Wu B, Janjigian YY, Mellinghoff IK, Diaz LA, Levine RL, Abou-Alfa GK, Stein EM, Intlekofer AM.

Cancer Discov. 2018 Dec;8(12):1540-1547. doi: 10.1158/2159-8290.CD-18-0877. Epub 2018 Oct 24.

PMID:
30355724
4.

Inhibition of epithelial cell migration and Src/FAK signaling by SIRT3.

Lee JJ, van de Ven RAH, Zaganjor E, Ng MR, Barakat A, Demmers JJPG, Finley LWS, Gonzalez Herrera KN, Hung YP, Harris IS, Jeong SM, Danuser G, McAllister SS, Haigis MC.

Proc Natl Acad Sci U S A. 2018 Jul 3;115(27):7057-7062. doi: 10.1073/pnas.1800440115. Epub 2018 Jun 18.

5.

Metabolic regulation of chromatin modifications and gene expression.

Schvartzman JM, Thompson CB, Finley LWS.

J Cell Biol. 2018 Jul 2;217(7):2247-2259. doi: 10.1083/jcb.201803061. Epub 2018 May 14. Review.

6.

Pluripotency transcription factors and Tet1/2 maintain Brd4-independent stem cell identity.

Finley LWS, Vardhana SA, Carey BW, Alonso-Curbelo D, Koche R, Chen Y, Wen D, King B, Radler MR, Rafii S, Lowe SW, Allis CD, Thompson CB.

Nat Cell Biol. 2018 May;20(5):565-574. doi: 10.1038/s41556-018-0086-3. Epub 2018 Apr 16.

7.

Adrenergic nerves activate an angio-metabolic switch in prostate cancer.

Zahalka AH, Arnal-Estapé A, Maryanovich M, Nakahara F, Cruz CD, Finley LWS, Frenette PS.

Science. 2017 Oct 20;358(6361):321-326. doi: 10.1126/science.aah5072.

8.

PHD3 Loss in Cancer Enables Metabolic Reliance on Fatty Acid Oxidation via Deactivation of ACC2.

German NJ, Yoon H, Yusuf RZ, Murphy JP, Finley LW, Laurent G, Haas W, Satterstrom FK, Guarnerio J, Zaganjor E, Santos D, Pandolfi PP, Beck AH, Gygi SP, Scadden DT, Kaelin WG Jr, Haigis MC.

Mol Cell. 2016 Sep 15;63(6):1006-20. doi: 10.1016/j.molcel.2016.08.014.

9.

Hypoxia Induces Production of L-2-Hydroxyglutarate.

Intlekofer AM, Dematteo RG, Venneti S, Finley LW, Lu C, Judkins AR, Rustenburg AS, Grinaway PB, Chodera JD, Cross JR, Thompson CB.

Cell Metab. 2015 Aug 4;22(2):304-11. doi: 10.1016/j.cmet.2015.06.023. Epub 2015 Jul 23.

10.

Intracellular α-ketoglutarate maintains the pluripotency of embryonic stem cells.

Carey BW, Finley LW, Cross JR, Allis CD, Thompson CB.

Nature. 2015 Feb 19;518(7539):413-6. doi: 10.1038/nature13981. Epub 2014 Dec 10.

11.

Serine catabolism regulates mitochondrial redox control during hypoxia.

Ye J, Fan J, Venneti S, Wan YW, Pawel BR, Zhang J, Finley LW, Lu C, Lindsten T, Cross JR, Qing G, Liu Z, Simon MC, Rabinowitz JD, Thompson CB.

Cancer Discov. 2014 Dec;4(12):1406-17. doi: 10.1158/2159-8290.CD-14-0250. Epub 2014 Sep 3.

12.

SIRT3 regulates cellular iron metabolism and cancer growth by repressing iron regulatory protein 1.

Jeong SM, Lee J, Finley LW, Schmidt PJ, Fleming MD, Haigis MC.

Oncogene. 2015 Apr 16;34(16):2115-24. doi: 10.1038/onc.2014.124. Epub 2014 Jun 9.

13.

SIRT4 represses peroxisome proliferator-activated receptor α activity to suppress hepatic fat oxidation.

Laurent G, de Boer VC, Finley LW, Sweeney M, Lu H, Schug TT, Cen Y, Jeong SM, Li X, Sauve AA, Haigis MC.

Mol Cell Biol. 2013 Nov;33(22):4552-61. doi: 10.1128/MCB.00087-13. Epub 2013 Sep 16.

14.

SIRT4 has tumor-suppressive activity and regulates the cellular metabolic response to DNA damage by inhibiting mitochondrial glutamine metabolism.

Jeong SM, Xiao C, Finley LW, Lahusen T, Souza AL, Pierce K, Li YH, Wang X, Laurent G, German NJ, Xu X, Li C, Wang RH, Lee J, Csibi A, Cerione R, Blenis J, Clish CB, Kimmelman A, Deng CX, Haigis MC.

Cancer Cell. 2013 Apr 15;23(4):450-63. doi: 10.1016/j.ccr.2013.02.024. Epub 2013 Apr 4.

15.

Altered social behavior and neuronal development in mice lacking the Uba6-Use1 ubiquitin transfer system.

Lee PC, Dodart JC, Aron L, Finley LW, Bronson RT, Haigis MC, Yankner BA, Harper JW.

Mol Cell. 2013 Apr 25;50(2):172-84. doi: 10.1016/j.molcel.2013.02.014. Epub 2013 Mar 14.

16.

SnapShot: cancer metabolism pathways.

Finley LW, Zhang J, Ye J, Ward PS, Thompson CB.

Cell Metab. 2013 Mar 5;17(3):466-466.e2. doi: 10.1016/j.cmet.2013.02.016. No abstract available.

17.

A novel AMPK-dependent FoxO3A-SIRT3 intramitochondrial complex sensing glucose levels.

Peserico A, Chiacchiera F, Grossi V, Matrone A, Latorre D, Simonatto M, Fusella A, Ryall JG, Finley LW, Haigis MC, Villani G, Puri PL, Sartorelli V, Simone C.

Cell Mol Life Sci. 2013 Jun;70(11):2015-29. doi: 10.1007/s00018-012-1244-6. Epub 2013 Jan 3.

PMID:
23283301
18.

Acetylation-dependent regulation of Skp2 function.

Inuzuka H, Gao D, Finley LW, Yang W, Wan L, Fukushima H, Chin YR, Zhai B, Shaik S, Lau AW, Wang Z, Gygi SP, Nakayama K, Teruya-Feldstein J, Toker A, Haigis MC, Pandolfi PP, Wei W.

Cell. 2012 Jul 6;150(1):179-93. doi: 10.1016/j.cell.2012.05.038.

19.

Metabolic regulation by SIRT3: implications for tumorigenesis.

Finley LW, Haigis MC.

Trends Mol Med. 2012 Sep;18(9):516-23. doi: 10.1016/j.molmed.2012.05.004. Epub 2012 Jun 27. Review.

20.

SIRT3 is a mitochondrial tumor suppressor: a scientific tale that connects aberrant cellular ROS, the Warburg effect, and carcinogenesis.

Haigis MC, Deng CX, Finley LW, Kim HS, Gius D.

Cancer Res. 2012 May 15;72(10):2468-72. doi: 10.1158/0008-5472.CAN-11-3633.

21.

Short-term calorie restriction enhances skeletal muscle stem cell function.

Cerletti M, Jang YC, Finley LW, Haigis MC, Wagers AJ.

Cell Stem Cell. 2012 May 4;10(5):515-9. doi: 10.1016/j.stem.2012.04.002.

22.

Skeletal muscle transcriptional coactivator PGC-1α mediates mitochondrial, but not metabolic, changes during calorie restriction.

Finley LW, Lee J, Souza A, Desquiret-Dumas V, Bullock K, Rowe GC, Procaccio V, Clish CB, Arany Z, Haigis MC.

Proc Natl Acad Sci U S A. 2012 Feb 21;109(8):2931-6. doi: 10.1073/pnas.1115813109. Epub 2012 Feb 3.

23.

Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity.

Finley LW, Haas W, Desquiret-Dumas V, Wallace DC, Procaccio V, Gygi SP, Haigis MC.

PLoS One. 2011;6(8):e23295. doi: 10.1371/journal.pone.0023295. Epub 2011 Aug 17.

24.

SIRT3 opposes reprogramming of cancer cell metabolism through HIF1α destabilization.

Finley LW, Carracedo A, Lee J, Souza A, Egia A, Zhang J, Teruya-Feldstein J, Moreira PI, Cardoso SM, Clish CB, Pandolfi PP, Haigis MC.

Cancer Cell. 2011 Mar 8;19(3):416-28. doi: 10.1016/j.ccr.2011.02.014.

25.

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling.

Verdin E, Hirschey MD, Finley LW, Haigis MC.

Trends Biochem Sci. 2010 Dec;35(12):669-75. doi: 10.1016/j.tibs.2010.07.003. Epub 2010 Sep 20. Review.

26.

The coordination of nuclear and mitochondrial communication during aging and calorie restriction.

Finley LW, Haigis MC.

Ageing Res Rev. 2009 Jul;8(3):173-88. doi: 10.1016/j.arr.2009.03.003. Epub 2009 Mar 27. Review.

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