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Thiol-based direct threat sensing by the stress-activated protein kinase Hog1.

Guerra-Moreno A, Prado MA, Ang J, Schnell HM, Micoogullari Y, Paulo JA, Finley D, Gygi SP, Hanna J.

Sci Signal. 2019 Nov 26;12(609). pii: eaaw4956. doi: 10.1126/scisignal.aaw4956.


Outcomes of an Intensive, Pre-Operative Smoking Cessation Program.

Fay KA, Phillips JD, Hasson RM, Fannin A, Millington TM, Finley DJ.

Ann Thorac Surg. 2019 Oct 3. pii: S0003-4975(19)31466-3. doi: 10.1016/j.athoracsur.2019.08.075. [Epub ahead of print]


N-Terminal Ubiquitination of Amyloidogenic Proteins Triggers Removal of their Oligomers by the Proteasome Holoenzyme.

Ye Y, Klenerman D, Finley D.

J Mol Biol. 2019 Sep 10. pii: S0022-2836(19)30545-5. doi: 10.1016/j.jmb.2019.08.021. [Epub ahead of print]


Editorial on expanded indications for robotic surgery in stage IIIA non-small cell lung cancer.

Phillips JD, Finley DJ.

J Thorac Dis. 2019 May;11(Suppl 9):S1172-S1174. doi: 10.21037/jtd.2019.04.10. No abstract available.


Salvage Cryoablation for Radiorecurrent Prostate Cancer: Initial Experience at a Regional Health Care System.

Safavy S, Jabaji RB, Lu SM, Slezak JM, Cosmatos HA, Williams SG, Finley DS.

Perm J. 2019;23. doi: 10.7812/TPP/18-153.


National practice trends for the surgical management of lung cancer in the CMS population: an atlas of care.

Phillips JD, Bostock IC, Hasson RM, Goodney PP, Goodman DC, Millington TM, Finley DJ.

J Thorac Dis. 2019 Mar;11(Suppl 4):S500-S508. doi: 10.21037/jtd.2019.01.05.


Tension hydrothorax secondary to small cell lung cancer.

Porter ED, Finley DJ, Phillips JD.

Respirol Case Rep. 2019 Apr 6;7(5):e00420. doi: 10.1002/rcr2.420. eCollection 2019 Jul.


Radical Prostatectomy and Pelvic Lymph Node Dissection in Kaiser Permanente Southern California: 15-Year Experience.

Banapour P, Schumacher A, Lin JC, Finley DS.

Perm J. 2019;23. pii: 17-233. doi: 10.7812/TPP/17-233.


The Proteasome and Its Network: Engineering for Adaptability.

Finley D, Prado MA.

Cold Spring Harb Perspect Biol. 2019 Mar 4. pii: a033985. doi: 10.1101/cshperspect.a033985. [Epub ahead of print]


Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme.

Cliffe R, Sang JC, Kundel F, Finley D, Klenerman D, Ye Y.

Cell Rep. 2019 Feb 19;26(8):2140-2149.e3. doi: 10.1016/j.celrep.2019.01.096.


Significant Excess of Electronlike Events in the MiniBooNE Short-Baseline Neutrino Experiment.

Aguilar-Arevalo AA, Brown BC, Bugel L, Cheng G, Conrad JM, Cooper RL, Dharmapalan R, Diaz A, Djurcic Z, Finley DA, Ford R, Garcia FG, Garvey GT, Grange J, Huang EC, Huelsnitz W, Ignarra C, Johnson RA, Karagiorgi G, Katori T, Kobilarcik T, Louis WC, Mariani C, Marsh W, Mills GB, Mirabal J, Monroe J, Moore CD, Mousseau J, Nienaber P, Nowak J, Osmanov B, Pavlovic Z, Perevalov D, Ray H, Roe BP, Russell AD, Shaevitz MH, Spitz J, Stancu I, Tayloe R, Thornton RT, Tzanov M, Van de Water RG, White DH, Wickremasinghe DA, Zimmerman ED; MiniBooNE Collaboration.

Phys Rev Lett. 2018 Nov 30;121(22):221801. doi: 10.1103/PhysRevLett.121.221801.


Cryo-EM structures and dynamics of substrate-engaged human 26S proteasome.

Dong Y, Zhang S, Wu Z, Li X, Wang WL, Zhu Y, Stoilova-McPhie S, Lu Y, Finley D, Mao Y.

Nature. 2019 Jan;565(7737):49-55. doi: 10.1038/s41586-018-0736-4. Epub 2018 Nov 12.


Molecular Mechanics Simulations and Improved Tight-Binding Hamiltonians for Artificial Light Harvesting Systems: Predicting Geometric Distributions, Disorder, and Spectroscopy of Chromophores in a Protein Environment.

Lee J, Lee D, Kocherzhenko AA, Greenman L, Finley DT, Francis MB, Whaley KB.

J Phys Chem B. 2018 Dec 27;122(51):12292-12301. doi: 10.1021/acs.jpcb.8b08858. Epub 2018 Dec 17.


Contemporary outcomes of surgical management of complex thoracic infections.

Bostock IC, Sheikh F, Millington TM, Finley DJ, Phillips JD.

J Thorac Dis. 2018 Sep;10(9):5421-5427. doi: 10.21037/jtd.2018.08.43.


The deubiquitinating enzyme Usp14 controls ciliogenesis and Hedgehog signaling.

Massa F, Tammaro R, Prado MA, Cesana M, Lee BH, Finley D, Franco B, Morleo M.

Hum Mol Genet. 2019 Mar 1;28(5):764-777. doi: 10.1093/hmg/ddy380.


Altered patterns of global protein synthesis and translational fidelity in RPS15-mutated chronic lymphocytic leukemia.

Bretones G, Álvarez MG, Arango JR, Rodríguez D, Nadeu F, Prado MA, Valdés-Mas R, Puente DA, Paulo JA, Delgado J, Villamor N, López-Guillermo A, Finley DJ, Gygi SP, Campo E, Quesada V, López-Otín C.

Blood. 2018 Nov 29;132(22):2375-2388. doi: 10.1182/blood-2017-09-804401. Epub 2018 Sep 4.


Robotic partial cystectomy for venous malformation of the bladder.

Jabaji R, Li V, Banapour P, Huang GO, Finley DS.

Urol Case Rep. 2018 Jul 6;20:65-66. doi: 10.1016/j.eucr.2018.07.003. eCollection 2018 Sep. No abstract available.


First Measurement of Monoenergetic Muon Neutrino Charged Current Interactions.

Aguilar-Arevalo AA, Brown BC, Bugel L, Cheng G, Church ED, Conrad JM, Cooper RL, Dharmapalan R, Djurcic Z, Finley DA, Fitzpatrick RS, Ford R, Garcia FG, Garvey GT, Grange J, Huelsnitz W, Ignarra C, Imlay R, Johnson RA, Jordan JR, Karagiorgi G, Katori T, Kobilarcik T, Louis WC, Mahn K, Mariani C, Marsh W, Mills GB, Mirabal J, Moore CD, Mousseau J, Nienaber P, Osmanov B, Pavlovic Z, Perevalov D, Ray H, Roe BP, Russell AD, Shaevitz MH, Spitz J, Stancu I, Tayloe R, Thornton RT, Van de Water RG, Wascko MO, White DH, Wickremasinghe DA, Zeller GP, Zimmerman ED; MiniBooNE Collaboration.

Phys Rev Lett. 2018 Apr 6;120(14):141802. doi: 10.1103/PhysRevLett.120.141802.


Meddling with Fate: The Proteasomal Deubiquitinating Enzymes.

de Poot SAH, Tian G, Finley D.

J Mol Biol. 2017 Nov 10;429(22):3525-3545. doi: 10.1016/j.jmb.2017.09.015. Epub 2017 Oct 5. Review.


An inhibitor of the proteasomal deubiquitinating enzyme USP14 induces tau elimination in cultured neurons.

Boselli M, Lee BH, Robert J, Prado MA, Min SW, Cheng C, Silva MC, Seong C, Elsasser S, Hatle KM, Gahman TC, Gygi SP, Haggarty SJ, Gan L, King RW, Finley D.

J Biol Chem. 2017 Nov 24;292(47):19209-19225. doi: 10.1074/jbc.M117.815126. Epub 2017 Sep 26.


Ubiquilin1 promotes antigen-receptor mediated proliferation by eliminating mislocalized mitochondrial proteins.

Whiteley AM, Prado MA, Peng I, Abbas AR, Haley B, Paulo JA, Reichelt M, Katakam A, Sagolla M, Modrusan Z, Lee DY, Roose-Girma M, Kirkpatrick DS, McKenzie BS, Gygi SP, Finley D, Brown EJ.

Elife. 2017 Sep 21;6. pii: e26435. doi: 10.7554/eLife.26435.


UBE2O remodels the proteome during terminal erythroid differentiation.

Nguyen AT, Prado MA, Schmidt PJ, Sendamarai AK, Wilson-Grady JT, Min M, Campagna DR, Tian G, Shi Y, Dederer V, Kawan M, Kuehnle N, Paulo JA, Yao Y, Weiss MJ, Justice MJ, Gygi SP, Fleming MD, Finley D.

Science. 2017 Aug 4;357(6350). pii: eaan0218. doi: 10.1126/science.aan0218.


Conformational Landscape of the p28-Bound Human Proteasome Regulatory Particle.

Lu Y, Wu J, Dong Y, Chen S, Sun S, Ma YB, Ouyang Q, Finley D, Kirschner MW, Mao Y.

Mol Cell. 2017 Jul 20;67(2):322-333.e6. doi: 10.1016/j.molcel.2017.06.007. Epub 2017 Jul 6.


Multi-omics analysis identifies ATF4 as a key regulator of the mitochondrial stress response in mammals.

Quirós PM, Prado MA, Zamboni N, D'Amico D, Williams RW, Finley D, Gygi SP, Auwerx J.

J Cell Biol. 2017 Jul 3;216(7):2027-2045. doi: 10.1083/jcb.201702058. Epub 2017 May 31.


Nodular Fasciitis of the Posterior Chest Wall With Bone Invasion Mimicking a Malignant Neoplasm.

Olson NJ, Finley DJ, Tsapakos MJ, Wong SL, Linos K.

Ann Thorac Surg. 2017 May;103(5):e405-e407. doi: 10.1016/j.athoracsur.2016.10.045.


Ubiquitylation of p62/sequestosome1 activates its autophagy receptor function and controls selective autophagy upon ubiquitin stress.

Peng H, Yang J, Li G, You Q, Han W, Li T, Gao D, Xie X, Lee BH, Du J, Hou J, Zhang T, Rao H, Huang Y, Li Q, Zeng R, Hui L, Wang H, Xia Q, Zhang X, He Y, Komatsu M, Dikic I, Finley D, Hu R.

Cell Res. 2017 May;27(5):657-674. doi: 10.1038/cr.2017.40. Epub 2017 Mar 21.


Nucleotide-dependent switch in proteasome assembly mediated by the Nas6 chaperone.

Li F, Tian G, Langager D, Sokolova V, Finley D, Park S.

Proc Natl Acad Sci U S A. 2017 Feb 14;114(7):1548-1553. doi: 10.1073/pnas.1612922114. Epub 2017 Jan 30.


Long-term Survival Based on the Surgical Approach to Lobectomy For Clinical Stage I Nonsmall Cell Lung Cancer: Comparison of Robotic, Video-assisted Thoracic Surgery, and Thoracotomy Lobectomy.

Yang HX, Woo KM, Sima CS, Bains MS, Adusumilli PS, Huang J, Finley DJ, Rizk NP, Rusch VW, Jones DR, Park BJ.

Ann Surg. 2017 Feb;265(2):431-437. doi: 10.1097/SLA.0000000000001708.


Structural basis for dynamic regulation of the human 26S proteasome.

Chen S, Wu J, Lu Y, Ma YB, Lee BH, Yu Z, Ouyang Q, Finley DJ, Kirschner MW, Mao Y.

Proc Natl Acad Sci U S A. 2016 Nov 15;113(46):12991-12996. Epub 2016 Oct 21.


Highly Multiplexed Quantitative Mass Spectrometry Analysis of Ubiquitylomes.

Rose CM, Isasa M, Ordureau A, Prado MA, Beausoleil SA, Jedrychowski MP, Finley DJ, Harper JW, Gygi SP.

Cell Syst. 2016 Oct 26;3(4):395-403.e4. doi: 10.1016/j.cels.2016.08.009. Epub 2016 Sep 22.


Stable Disk Assemblies of a Tobacco Mosaic Virus Mutant as Nanoscale Scaffolds for Applications in Drug Delivery.

Finbloom JA, Han K, Aanei IL, Hartman EC, Finley DT, Dedeo MT, Fishman M, Downing KH, Francis MB.

Bioconjug Chem. 2016 Oct 19;27(10):2480-2485. doi: 10.1021/acs.bioconjchem.6b00424. Epub 2016 Oct 7.


Attaining Proficiency in Robotic-Assisted Minimally Invasive Esophagectomy While Maximizing Safety During Procedure Development.

Sarkaria IS, Rizk NP, Grosser R, Goldman D, Finley DJ, Ghanie A, Sima CS, Bains MS, Adusumilli PS, Rusch VW, Jones DR.

Innovations (Phila). 2016 Jul-Aug;11(4):268-73. doi: 10.1097/IMI.0000000000000297.


Robot-Assisted Excision of a Urachal Cyst Causing Dyspareunia and Dysorgasmia: Report of a Case.

Kilday PS, Finley DS.

J Endourol Case Rep. 2016 Jan 1;2(1):3-5. doi: 10.1089/cren.2015.0029. eCollection 2016.


USP14 deubiquitinates proteasome-bound substrates that are ubiquitinated at multiple sites.

Lee BH, Lu Y, Prado MA, Shi Y, Tian G, Sun S, Elsasser S, Gygi SP, King RW, Finley D.

Nature. 2016 Apr 21;532(7599):398-401. doi: 10.1038/nature17433. Epub 2016 Apr 13.


Open-gate mutants of the mammalian proteasome show enhanced ubiquitin-conjugate degradation.

Choi WH, de Poot SA, Lee JH, Kim JH, Han DH, Kim YK, Finley D, Lee MJ.

Nat Commun. 2016 Mar 9;7:10963. doi: 10.1038/ncomms10963.


Structure of an endogenous yeast 26S proteasome reveals two major conformational states.

Luan B, Huang X, Wu J, Mei Z, Wang Y, Xue X, Yan C, Wang J, Finley DJ, Shi Y, Wang F.

Proc Natl Acad Sci U S A. 2016 Mar 8;113(10):2642-7. doi: 10.1073/pnas.1601561113. Epub 2016 Feb 29.


Rpn1 provides adjacent receptor sites for substrate binding and deubiquitination by the proteasome.

Shi Y, Chen X, Elsasser S, Stocks BB, Tian G, Lee BH, Shi Y, Zhang N, de Poot SA, Tuebing F, Sun S, Vannoy J, Tarasov SG, Engen JR, Finley D, Walters KJ.

Science. 2016 Feb 19;351(6275). pii: aad9421. doi: 10.1126/science.aad9421.


Gates, Channels, and Switches: Elements of the Proteasome Machine.

Finley D, Chen X, Walters KJ.

Trends Biochem Sci. 2016 Jan;41(1):77-93. doi: 10.1016/j.tibs.2015.10.009. Epub 2015 Nov 28. Review.


Pretreatment Dysphagia in Esophageal Cancer Patients May Eliminate the Need for Staging by Endoscopic Ultrasonography.

Ripley RT, Sarkaria IS, Grosser R, Sima CS, Bains MS, Jones DR, Adusumilli PS, Huang J, Finley DJ, Rusch VW, Rizk NP.

Ann Thorac Surg. 2016 Jan;101(1):226-230. doi: 10.1016/j.athoracsur.2015.06.062. Epub 2015 Oct 23.


Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system.

Xu D, Shan B, Lee BH, Zhu K, Zhang T, Sun H, Liu M, Shi L, Liang W, Qian L, Xiao J, Wang L, Pan L, Finley D, Yuan J.

Elife. 2015 Nov 2;4:e10510. doi: 10.7554/eLife.10510.


Multiplexed, Proteome-Wide Protein Expression Profiling: Yeast Deubiquitylating Enzyme Knockout Strains.

Isasa M, Rose CM, Elsasser S, Navarrete-Perea J, Paulo JA, Finley DJ, Gygi SP.

J Proteome Res. 2015 Dec 4;14(12):5306-17. doi: 10.1021/acs.jproteome.5b00802. Epub 2015 Nov 4.


Chylothorax and Recurrent Laryngeal Nerve Injury Associated With Robotic Video-Assisted Mediastinal Lymph Node Dissection.

Sarkaria IS, Finley DJ, Bains MS, Adusumilli PS, Rizk NP, Huang J, Downey RJ, Rusch VW, Jones DR.

Innovations (Phila). 2015 May-Jun;10(3):170-3. doi: 10.1097/IMI.0000000000000160.


Manipulating Excited-State Dynamics of Individual Light-Harvesting Chromophores through Restricted Motions in a Hydrated Nanoscale Protein Cavity.

Noriega R, Finley DT, Haberstroh J, Geissler PL, Francis MB, Ginsberg NS.

J Phys Chem B. 2015 Jun 11;119(23):6963-73. doi: 10.1021/acs.jpcb.5b03784. Epub 2015 Jun 2.


Substrate degradation by the proteasome: a single-molecule kinetic analysis.

Lu Y, Lee BH, King RW, Finley D, Kirschner MW.

Science. 2015 Apr 10;348(6231):1250834. doi: 10.1126/science.1250834.


Tumors of the Anterior Prostate: Implications for Diagnosis and Treatment.

Abdelsayed GA, Danial T, Kaswick JA, Finley DS.

Urology. 2015 Jun;85(6):1224-8. doi: 10.1016/j.urology.2014.12.035. Epub 2015 Feb 12. Review.


Interview with Delvecchio S. Finley, FACHE, CEO of Harbor-UCLA Medical Center.

Finley DS, O'Connor SJ.

J Healthc Manag. 2014 Sep-Oct;59(5):310-4. No abstract available.


K63 polyubiquitination is a new modulator of the oxidative stress response.

Silva GM, Finley D, Vogel C.

Nat Struct Mol Biol. 2015 Feb;22(2):116-23. doi: 10.1038/nsmb.2955. Epub 2015 Jan 26.


Endovascular approach to acute hemorrhage in locally advanced breast cancer.

Ugras S, Gemignani ML, Connolly PH, Finley DJ.

Breast J. 2015 Mar-Apr;21(2):189-91. doi: 10.1111/tbj.12373. Epub 2015 Jan 21.


Prognostic nomogram to predict survival after surgery for synchronous multiple lung cancers in multiple lobes.

Tanvetyanon T, Finley DJ, Fabian T, Riquet M, Voltolini L, Kocaturk C, Bryant A, Robinson L.

J Thorac Oncol. 2015 Feb;10(2):338-45. doi: 10.1097/JTO.0000000000000400.


Sculpting the proteome with small molecules.

King RW, Finley D.

Nat Chem Biol. 2014 Nov;10(11):870-4. doi: 10.1038/nchembio.1671. No abstract available.

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