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Items: 1 to 50 of 96

1.

Aerosol drug delivery to the lungs during nasal high flow therapy: an in vitro study.

Wallin M, Tang P, Chang RYK, Yang M, Finlay WH, Chan HK.

BMC Pulm Med. 2019 Feb 15;19(1):42. doi: 10.1186/s12890-019-0807-9.

2.

In Vitro-In Silico Comparison of Pulsed Oxygen Delivery From Portable Oxygen Concentrators Versus Continuous Flow Oxygen Delivery.

Chen JZ, Katz IM, Pichelin M, Zhu K, Caillibotte G, Finlay WH, Martin AR.

Respir Care. 2019 Feb;64(2):117-129. doi: 10.4187/respcare.06359. Epub 2019 Jan 29.

PMID:
30696754
3.

Experimental evaluation of pressure drop for flows of air and heliox through upper and central conducting airway replicas of 4- to 8-year-old children.

Paxman T, Noga M, Finlay WH, Martin AR.

J Biomech. 2019 Jan 3;82:134-141. doi: 10.1016/j.jbiomech.2018.10.028. Epub 2018 Oct 27.

PMID:
30522876
4.

Jet nebulization of bacteriophages with different tail morphologies - Structural effects.

Leung SSY, Carrigy NB, Vehring R, Finlay WH, Morales S, Carter EA, Britton WJ, Kutter E, Chan HK.

Int J Pharm. 2019 Jan 10;554:322-326. doi: 10.1016/j.ijpharm.2018.11.026. Epub 2018 Nov 13.

PMID:
30445174
5.

Models of deposition, pharmacokinetics, and intersubject variability in respiratory drug delivery.

Martin AR, Moore CP, Finlay WH.

Expert Opin Drug Deliv. 2018 Dec;15(12):1175-1188. doi: 10.1080/17425247.2018.1544616. Epub 2018 Nov 14.

PMID:
30388902
6.

Effect of storage temperature on the stability of spray dried bacteriophage powders.

Leung SSY, Parumasivam T, Nguyen A, Gengenbach T, Carter EA, Carrigy NB, Wang H, Vehring R, Finlay WH, Morales S, Britton WJ, Kutter E, Chan HK.

Eur J Pharm Biopharm. 2018 Jun;127:213-222. doi: 10.1016/j.ejpb.2018.02.033. Epub 2018 Feb 24.

PMID:
29486303
7.

Regional deposition of nasal sprays in adults: A wide ranging computational study.

Kiaee M, Wachtel H, Noga ML, Martin AR, Finlay WH.

Int J Numer Method Biomed Eng. 2018 May;34(5):e2968. doi: 10.1002/cnm.2968. Epub 2018 Mar 25.

PMID:
29453801
8.

Correlation of high flow nasal cannula outlet area with gas clearance and pressure in adult upper airway replicas.

Moore CP, Katz IM, Caillibotte G, Finlay WH, Martin AR.

Clin Biomech (Bristol, Avon). 2017 Nov 11. pii: S0268-0033(17)30281-4. doi: 10.1016/j.clinbiomech.2017.11.003. [Epub ahead of print]

PMID:
29174453
9.

An In Vitro Examination of the Effects of Altitude on Dry Powder Inhaler Performance.

Ruzycki CA, Martin AR, Vehring R, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2018 Aug;31(4):221-236. doi: 10.1089/jamp.2017.1417. Epub 2017 Nov 10.

PMID:
29125912
10.

Comparison of pulsed versus continuous oxygen delivery using realistic adult nasal airway replicas.

Chen JZ, Katz IM, Pichelin M, Zhu K, Caillibotte G, Noga ML, Finlay WH, Martin AR.

Int J Chron Obstruct Pulmon Dis. 2017 Aug 24;12:2559-2571. doi: 10.2147/COPD.S141976. eCollection 2017.

11.

Powder aerosol delivery through nasal high-flow system: In vitro feasibility and influence of process conditions.

Okuda T, Tang P, Yu J, Finlay WH, Chan HK.

Int J Pharm. 2017 Nov 25;533(1):187-197. doi: 10.1016/j.ijpharm.2017.08.079. Epub 2017 Aug 19.

PMID:
28830783
12.

Model Calculations of Regional Deposition and Disposition for Single Doses of Inhaled Liposomal and Dry Powder Ciprofloxacin.

Martin AR, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2018 Feb;31(1):49-60. doi: 10.1089/jamp.2017.1377. Epub 2017 Jul 14.

PMID:
28708440
13.

Anti-Tuberculosis Bacteriophage D29 Delivery with a Vibrating Mesh Nebulizer, Jet Nebulizer, and Soft Mist Inhaler.

Carrigy NB, Chang RY, Leung SSY, Harrison M, Petrova Z, Pope WH, Hatfull GF, Britton WJ, Chan HK, Sauvageau D, Finlay WH, Vehring R.

Pharm Res. 2017 Oct;34(10):2084-2096. doi: 10.1007/s11095-017-2213-4. Epub 2017 Jun 23.

PMID:
28646325
14.

Theoretical and experimental evaluation of the effects of an argon gas mixture on the pressure drop through adult tracheobronchial airway replicas.

Litwin PD, Reis Dib AL, Chen J, Noga M, Finlay WH, Martin AR.

J Biomech. 2017 Jun 14;58:217-221. doi: 10.1016/j.jbiomech.2017.04.002. Epub 2017 Apr 18.

PMID:
28478944
15.

Humidity affects the morphology of particles emitted from beclomethasone dipropionate pressurized metered dose inhalers.

Ivey JW, Bhambri P, Church TK, Lewis DA, McDermott MT, Elbayomy S, Finlay WH, Vehring R.

Int J Pharm. 2017 Mar 30;520(1-2):207-215. doi: 10.1016/j.ijpharm.2017.01.062. Epub 2017 Feb 3.

PMID:
28167262
16.

Effects of storage conditions on the stability of spray dried, inhalable bacteriophage powders.

Leung SSY, Parumasivam T, Gao FG, Carter EA, Carrigy NB, Vehring R, Finlay WH, Morales S, Britton WJ, Kutter E, Chan HK.

Int J Pharm. 2017 Apr 15;521(1-2):141-149. doi: 10.1016/j.ijpharm.2017.01.060. Epub 2017 Feb 3.

17.

The effect of device resistance and inhalation flow rate on the lung deposition of orally inhaled mannitol dry powder.

Yang MY, Verschuer J, Shi Y, Song Y, Katsifis A, Eberl S, Wong K, Brannan JD, Cai W, Finlay WH, Chan HK.

Int J Pharm. 2016 Nov 20;513(1-2):294-301. doi: 10.1016/j.ijpharm.2016.09.047. Epub 2016 Sep 14.

PMID:
27639621
18.

Dry Powder Inhaler Delivery of Tobramycin in In Vitro Models of Tracheostomized Children.

Wee WB, Tavernini S, Martin AR, Amirav I, Majaesic C, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2017 Feb;30(1):64-70. doi: 10.1089/jamp.2016.1309. Epub 2016 Aug 26.

PMID:
27563934
19.

Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections.

Leung SS, Parumasivam T, Gao FG, Carrigy NB, Vehring R, Finlay WH, Morales S, Britton WJ, Kutter E, Chan HK.

Pharm Res. 2016 Jun;33(6):1486-96. doi: 10.1007/s11095-016-1892-6. Epub 2016 Feb 29.

20.

Use of Extrathoracic Deposition Models for Patient-Specific Dose Estimation during Inhaler Design.

Carrigy NB, Martin AR, Finlay WH.

Curr Pharm Des. 2015;21(27):3984-92. Review.

PMID:
26290196
21.

Simulation of muscle and adipose tissue deformation in the passive human pharynx.

Carrigy NB, Carey JP, Martin AR, Remmers JE, Zareian A, Topor Z, Grosse J, Noga M, Finlay WH.

Comput Methods Biomech Biomed Engin. 2016;19(7):780-8. doi: 10.1080/10255842.2015.1062477. Epub 2015 Jul 27.

PMID:
26213804
22.

Validation of airway resistance models for predicting pressure loss through anatomically realistic conducting airway replicas of adults and children.

Borojeni AA, Noga ML, Martin AR, Finlay WH.

J Biomech. 2015 Jul 16;48(10):1988-96. doi: 10.1016/j.jbiomech.2015.03.035. Epub 2015 Apr 7.

PMID:
25912661
23.

An Apparatus to Deliver Mannitol Powder for Bronchial Provocation in Children Under Six Years Old.

Tang P, Leung SS, Hor E, Ruzycki CA, Carrigy NB, Finlay WH, Brannan JD, Devadason S, Anderson SD, Sly PD, Samnick K, Chan HK.

J Aerosol Med Pulm Drug Deliv. 2015 Dec;28(6):452-61. doi: 10.1089/jamp.2015.1208. Epub 2015 Apr 6.

PMID:
25844950
24.

Nebulizers for drug delivery to the lungs.

Martin AR, Finlay WH.

Expert Opin Drug Deliv. 2015 Jun;12(6):889-900. doi: 10.1517/17425247.2015.995087. Epub 2014 Dec 23. Review.

PMID:
25534396
25.

Understanding pressurized metered dose inhaler performance.

Ivey JW, Vehring R, Finlay WH.

Expert Opin Drug Deliv. 2015 Jun;12(6):901-16. doi: 10.1517/17425247.2015.984683. Epub 2014 Dec 13. Review.

PMID:
25496601
26.

Performance of pressurized metered-dose inhalers at extreme temperature conditions.

Morin CMD, Ivey JW, Titosky JTF, Suderman JD, Olfert JS, Vehring R, Finlay WH.

J Pharm Sci. 2014 Nov;103(11):3553-3559. doi: 10.1002/jps.24145. Epub 2014 Sep 22.

PMID:
25252183
27.

The effect of altitude on inhaler performance.

Titosky JTF, Morin CMD, Suderman JD, Olfert JS, Finlay WH, Vehring R.

J Pharm Sci. 2014 Jul;103(7):2116-2124. doi: 10.1002/jps.24032. Epub 2014 Jun 2.

PMID:
24890630
28.

Pediatric in vitro and in silico models of deposition via oral and nasal inhalation.

Carrigy NB, Ruzycki CA, Golshahi L, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2014 Jun;27(3):149-69. doi: 10.1089/jamp.2013.1075. Review.

PMID:
24870701
29.

Aerosol phage therapy efficacy in Burkholderia cepacia complex respiratory infections.

Semler DD, Goudie AD, Finlay WH, Dennis JJ.

Antimicrob Agents Chemother. 2014 Jul;58(7):4005-13. doi: 10.1128/AAC.02388-13. Epub 2014 May 5.

30.

Effect of electrostatic charge on deposition of uniformly charged monodisperse particles in the nasal extrathoracic airways of an infant.

Azhdarzadeh M, Olfert JS, Vehring R, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2015 Feb;28(1):30-4. doi: 10.1089/jamp.2013.1118. Epub 2014 Apr 1.

PMID:
24689985
31.

A correlation equation for the mass median aerodynamic diameter of the aerosol emitted by solution metered dose inhalers.

Ivey JW, Lewis D, Church T, Finlay WH, Vehring R.

Int J Pharm. 2014 Apr 25;465(1-2):18-24. doi: 10.1016/j.ijpharm.2014.01.039. Epub 2014 Feb 11.

PMID:
24524827
32.

Comparison of in vitro deposition of pharmaceutical aerosols in an idealized child throat with in vivo deposition in the upper respiratory tract of children.

Ruzycki CA, Golshahi L, Vehring R, Finlay WH.

Pharm Res. 2014 Jun;31(6):1525-35. doi: 10.1007/s11095-013-1258-2. Epub 2014 Jan 7.

PMID:
24395403
33.

Manufacturing and device options for the delivery of biotherapeutics.

Hoe S, Boraey MA, Ivey JW, Finlay WH, Vehring R.

J Aerosol Med Pulm Drug Deliv. 2014 Oct;27(5):315-28. doi: 10.1089/jamp.2013.1090. Epub 2013 Dec 3. Review.

PMID:
24299502
34.

Effect of facial material softness and applied force on face mask dead volume, face mask seal, and inhaled corticosteroid delivery through an idealized infant replica.

Carrigy NB, O'Reilly C, Schmitt J, Noga M, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2014 Aug;27(4):290-8. doi: 10.1089/jamp.2013.1087. Epub 2013 Nov 12.

PMID:
24219815
35.

Use of a fundamental approach to spray-drying formulation design to facilitate the development of multi-component dry powder aerosols for respiratory drug delivery.

Hoe S, Ivey JW, Boraey MA, Shamsaddini-Shahrbabak A, Javaheri E, Matinkhoo S, Finlay WH, Vehring R.

Pharm Res. 2014 Feb;31(2):449-65. doi: 10.1007/s11095-013-1174-5. Epub 2013 Aug 23.

PMID:
23974958
36.

Topical contrast agents to improve soft-tissue contrast in the upper airway using cone beam CT: a pilot study.

Alsufyani NA, Noga ML, Finlay WH, Major PW.

Dentomaxillofac Radiol. 2013;42(7):20130022. doi: 10.1259/dmfr.20130022. Epub 2013 Apr 26.

37.

Respirable bacteriophages for the treatment of bacterial lung infections.

Hoe S, Semler DD, Goudie AD, Lynch KH, Matinkhoo S, Finlay WH, Dennis JJ, Vehring R.

J Aerosol Med Pulm Drug Deliv. 2013 Dec;26(6):317-35. doi: 10.1089/jamp.2012.1001. Epub 2013 Apr 18. Review.

PMID:
23597003
38.

An in vitro study on the deposition of micrometer-sized particles in the extrathoracic airways of adults during tidal oral breathing.

Golshahi L, Noga ML, Vehring R, Finlay WH.

Ann Biomed Eng. 2013 May;41(5):979-89. doi: 10.1007/s10439-013-0747-0. Epub 2013 Jan 29.

PMID:
23358802
39.

The use of computational fluid dynamics in inhaler design.

Ruzycki CA, Javaheri E, Finlay WH.

Expert Opin Drug Deliv. 2013 Mar;10(3):307-23. doi: 10.1517/17425247.2013.753053. Epub 2013 Jan 7. Review.

PMID:
23289401
40.

In vitro investigation of the effect of ambient humidity on regional delivered dose with solution and suspension MDIs.

Shemirani FM, Hoe S, Lewis D, Church T, Vehring R, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2013 Aug;26(4):215-22. doi: 10.1089/jamp.2012.0991. Epub 2012 Oct 24.

PMID:
23094687
41.

Distribution of effervescent inhalable nanoparticles after pulmonary delivery: an in vivo study.

Al-Hallak MH, Sarfraz MK, Azarmi S, Roa WH, Finlay WH, Rouleau C, Löbenberg R.

Ther Deliv. 2012 Jun;3(6):725-34.

PMID:
22838068
42.

Pulmonary delivery of inhalable nanoparticles: dry powder inhalers.

Al-Hallak MH, Sarfraz MK, Azarmi S, Roa WH, Finlay WH, Löbenberg R.

Ther Deliv. 2011 Oct;2(10):1313-24. Review.

PMID:
22826885
43.

Simulation of enhanced deposition due to magnetic field alignment of ellipsoidal particles in a lung bifurcation.

Martinez RC, Roshchenko A, Minev P, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2013 Feb;26(1):31-40. doi: 10.1089/jamp.2011.0921. Epub 2012 May 2.

PMID:
22551082
44.

A pilot study on the use of geometrically accurate face models to replicate ex vivo N95 mask fit.

Golshahi L, Telidetzki K, King B, Shaw D, Finlay WH.

Am J Infect Control. 2013 Jan;41(1):77-9. doi: 10.1016/j.ajic.2012.01.008. Epub 2012 Apr 13.

PMID:
22503133
45.

Using MRI to measure aerosol deposition.

Thompson RB, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2012 Apr;25(2):55-62. doi: 10.1089/jamp.2011.0897. Review.

PMID:
22463490
46.

Spray-dried respirable powders containing bacteriophages for the treatment of pulmonary infections.

Matinkhoo S, Lynch KH, Dennis JJ, Finlay WH, Vehring R.

J Pharm Sci. 2011 Dec;100(12):5197-205. doi: 10.1002/jps.22715. Epub 2011 Aug 23.

PMID:
22020816
47.

In vivo-in vitro correlations: predicting pulmonary drug deposition from pharmaceutical aerosols.

Byron PR, Hindle M, Lange CF, Longest PW, McRobbie D, Oldham MJ, Olsson B, Thiel CG, Wachtel H, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2010 Dec;23 Suppl 2:S59-69. doi: 10.1089/jamp.2010.0846. Review.

PMID:
21133801
48.

Inhalable nanoparticles, a non-invasive approach to treat lung cancer in a mouse model.

Roa WH, Azarmi S, Al-Hallak MH, Finlay WH, Magliocco AM, Löbenberg R.

J Control Release. 2011 Feb 28;150(1):49-55. doi: 10.1016/j.jconrel.2010.10.035. Epub 2010 Nov 6.

PMID:
21059378
49.

In vitro lung delivery of bacteriophages KS4-M and ΦKZ using dry powder inhalers for treatment of Burkholderia cepacia complex and Pseudomonas aeruginosa infections in cystic fibrosis.

Golshahi L, Lynch KH, Dennis JJ, Finlay WH.

J Appl Microbiol. 2011 Jan;110(1):106-17. doi: 10.1111/j.1365-2672.2010.04863.x. Epub 2010 Sep 28.

50.

Changes in collection efficiency in nylon net filter media through magnetic alignment of elongated aerosol particles.

Lam CO, Finlay WH.

J Occup Environ Hyg. 2009 Oct;6(10):648-57. doi: 10.1080/15459620903139136.

PMID:
19693722

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