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Items: 1 to 50 of 103

1.

An Exploration of Factors Affecting In Vitro Deposition of Pharmaceutical Aerosols in the Alberta Idealized Throat.

Ruzycki CA, Martin AR, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2019 Aug 16. doi: 10.1089/jamp.2019.1531. [Epub ahead of print]

PMID:
31418632
2.

Correction to: Multi-Solvent Microdroplet Evaporation: Modeling and Measurement of Spray-Drying Kinetics with Inhalable Pharmaceutics.

Ordoubadi M, Gregson FKA, Melhem O, Barona D, Miles REH, D'Sa D, Gracin S, Lechuga-Ballesteros D, Reid JP, Finlay WH, Vehring R.

Pharm Res. 2019 May 29;36(8):111. doi: 10.1007/s11095-019-2648-x.

PMID:
31144049
3.

Multi-Solvent Microdroplet Evaporation: Modeling and Measurement of Spray-Drying Kinetics with Inhalable Pharmaceutics.

Ordoubadi M, Gregson FKA, Melhem O, Barona D, Miles REH, D'Sa D, Gracin S, Lechuga-Ballesteros D, Reid JP, Finlay WH, Vehring R.

Pharm Res. 2019 May 14;36(7):100. doi: 10.1007/s11095-019-2630-7. Erratum in: Pharm Res. 2019 May 29;36(8):111.

PMID:
31089892
4.

High flow nasal cannula: Influence of gas type and flow rate on airway pressure and CO2 clearance in adult nasal airway replicas.

Moore CP, Katz IM, Pichelin M, Caillibotte G, Finlay WH, Martin AR.

Clin Biomech (Bristol, Avon). 2019 May;65:73-80. doi: 10.1016/j.clinbiomech.2019.04.004. Epub 2019 Apr 6.

PMID:
30991233
5.

Amorphous pullulan trehalose microparticle platform for respiratory delivery.

Carrigy NB, Ordoubadi M, Liu Y, Melhem O, Barona D, Wang H, Milburn L, Ruzycki CA, Finlay WH, Vehring R.

Int J Pharm. 2019 May 30;563:156-168. doi: 10.1016/j.ijpharm.2019.04.004. Epub 2019 Apr 2.

PMID:
30951858
6.

Atmospheric Spray Freeze Drying of Sugar Solution With Phage D29.

Ly A, Carrigy NB, Wang H, Harrison M, Sauvageau D, Martin AR, Vehring R, Finlay WH.

Front Microbiol. 2019 Mar 20;10:488. doi: 10.3389/fmicb.2019.00488. eCollection 2019.

7.

An idealized geometry that mimics average nasal spray deposition in adults: A computational study.

Kiaee M, Wachtel H, Noga ML, Martin AR, Finlay WH.

Comput Biol Med. 2019 Apr;107:206-217. doi: 10.1016/j.compbiomed.2019.02.013. Epub 2019 Feb 26.

PMID:
30851506
8.

Aerosol drug delivery to the lungs during nasal high flow therapy: an in vitro study.

Wallin M, Tang P, Chang RYK, Yang M, Finlay WH, Chan HK.

BMC Pulm Med. 2019 Feb 15;19(1):42. doi: 10.1186/s12890-019-0807-9.

9.

In Vitro-In Silico Comparison of Pulsed Oxygen Delivery From Portable Oxygen Concentrators Versus Continuous Flow Oxygen Delivery.

Chen JZ, Katz IM, Pichelin M, Zhu K, Caillibotte G, Finlay WH, Martin AR.

Respir Care. 2019 Feb;64(2):117-129. doi: 10.4187/respcare.06359. Epub 2019 Jan 29.

PMID:
30696754
10.

Experimental evaluation of pressure drop for flows of air and heliox through upper and central conducting airway replicas of 4- to 8-year-old children.

Paxman T, Noga M, Finlay WH, Martin AR.

J Biomech. 2019 Jan 3;82:134-141. doi: 10.1016/j.jbiomech.2018.10.028. Epub 2018 Oct 27.

PMID:
30522876
11.

Jet nebulization of bacteriophages with different tail morphologies - Structural effects.

Leung SSY, Carrigy NB, Vehring R, Finlay WH, Morales S, Carter EA, Britton WJ, Kutter E, Chan HK.

Int J Pharm. 2019 Jan 10;554:322-326. doi: 10.1016/j.ijpharm.2018.11.026. Epub 2018 Nov 13.

PMID:
30445174
12.

Models of deposition, pharmacokinetics, and intersubject variability in respiratory drug delivery.

Martin AR, Moore CP, Finlay WH.

Expert Opin Drug Deliv. 2018 Dec;15(12):1175-1188. doi: 10.1080/17425247.2018.1544616. Epub 2018 Nov 14. Review.

PMID:
30388902
13.

Effect of storage temperature on the stability of spray dried bacteriophage powders.

Leung SSY, Parumasivam T, Nguyen A, Gengenbach T, Carter EA, Carrigy NB, Wang H, Vehring R, Finlay WH, Morales S, Britton WJ, Kutter E, Chan HK.

Eur J Pharm Biopharm. 2018 Jun;127:213-222. doi: 10.1016/j.ejpb.2018.02.033. Epub 2018 Feb 24.

14.

Regional deposition of nasal sprays in adults: A wide ranging computational study.

Kiaee M, Wachtel H, Noga ML, Martin AR, Finlay WH.

Int J Numer Method Biomed Eng. 2018 May;34(5):e2968. doi: 10.1002/cnm.2968. Epub 2018 Mar 25.

PMID:
29453801
15.

Correlation of high flow nasal cannula outlet area with gas clearance and pressure in adult upper airway replicas.

Moore CP, Katz IM, Caillibotte G, Finlay WH, Martin AR.

Clin Biomech (Bristol, Avon). 2019 Jun;66:66-73. doi: 10.1016/j.clinbiomech.2017.11.003. Epub 2017 Nov 11.

PMID:
29174453
16.

An In Vitro Examination of the Effects of Altitude on Dry Powder Inhaler Performance.

Ruzycki CA, Martin AR, Vehring R, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2018 Aug;31(4):221-236. doi: 10.1089/jamp.2017.1417. Epub 2017 Nov 10.

PMID:
29125912
17.

Comparison of pulsed versus continuous oxygen delivery using realistic adult nasal airway replicas.

Chen JZ, Katz IM, Pichelin M, Zhu K, Caillibotte G, Noga ML, Finlay WH, Martin AR.

Int J Chron Obstruct Pulmon Dis. 2017 Aug 24;12:2559-2571. doi: 10.2147/COPD.S141976. eCollection 2017.

18.

Powder aerosol delivery through nasal high-flow system: In vitro feasibility and influence of process conditions.

Okuda T, Tang P, Yu J, Finlay WH, Chan HK.

Int J Pharm. 2017 Nov 25;533(1):187-197. doi: 10.1016/j.ijpharm.2017.08.079. Epub 2017 Aug 19.

PMID:
28830783
19.

Model Calculations of Regional Deposition and Disposition for Single Doses of Inhaled Liposomal and Dry Powder Ciprofloxacin.

Martin AR, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2018 Feb;31(1):49-60. doi: 10.1089/jamp.2017.1377. Epub 2017 Jul 14.

PMID:
28708440
20.

Anti-Tuberculosis Bacteriophage D29 Delivery with a Vibrating Mesh Nebulizer, Jet Nebulizer, and Soft Mist Inhaler.

Carrigy NB, Chang RY, Leung SSY, Harrison M, Petrova Z, Pope WH, Hatfull GF, Britton WJ, Chan HK, Sauvageau D, Finlay WH, Vehring R.

Pharm Res. 2017 Oct;34(10):2084-2096. doi: 10.1007/s11095-017-2213-4. Epub 2017 Jun 23.

PMID:
28646325
21.

Theoretical and experimental evaluation of the effects of an argon gas mixture on the pressure drop through adult tracheobronchial airway replicas.

Litwin PD, Reis Dib AL, Chen J, Noga M, Finlay WH, Martin AR.

J Biomech. 2017 Jun 14;58:217-221. doi: 10.1016/j.jbiomech.2017.04.002. Epub 2017 Apr 18.

PMID:
28478944
22.

Humidity affects the morphology of particles emitted from beclomethasone dipropionate pressurized metered dose inhalers.

Ivey JW, Bhambri P, Church TK, Lewis DA, McDermott MT, Elbayomy S, Finlay WH, Vehring R.

Int J Pharm. 2017 Mar 30;520(1-2):207-215. doi: 10.1016/j.ijpharm.2017.01.062. Epub 2017 Feb 3.

PMID:
28167262
23.

Effects of storage conditions on the stability of spray dried, inhalable bacteriophage powders.

Leung SSY, Parumasivam T, Gao FG, Carter EA, Carrigy NB, Vehring R, Finlay WH, Morales S, Britton WJ, Kutter E, Chan HK.

Int J Pharm. 2017 Apr 15;521(1-2):141-149. doi: 10.1016/j.ijpharm.2017.01.060. Epub 2017 Feb 3.

24.

The effect of device resistance and inhalation flow rate on the lung deposition of orally inhaled mannitol dry powder.

Yang MY, Verschuer J, Shi Y, Song Y, Katsifis A, Eberl S, Wong K, Brannan JD, Cai W, Finlay WH, Chan HK.

Int J Pharm. 2016 Nov 20;513(1-2):294-301. doi: 10.1016/j.ijpharm.2016.09.047. Epub 2016 Sep 14.

PMID:
27639621
25.

Dry Powder Inhaler Delivery of Tobramycin in In Vitro Models of Tracheostomized Children.

Wee WB, Tavernini S, Martin AR, Amirav I, Majaesic C, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2017 Feb;30(1):64-70. doi: 10.1089/jamp.2016.1309. Epub 2016 Aug 26.

PMID:
27563934
26.

Production of Inhalation Phage Powders Using Spray Freeze Drying and Spray Drying Techniques for Treatment of Respiratory Infections.

Leung SS, Parumasivam T, Gao FG, Carrigy NB, Vehring R, Finlay WH, Morales S, Britton WJ, Kutter E, Chan HK.

Pharm Res. 2016 Jun;33(6):1486-96. doi: 10.1007/s11095-016-1892-6. Epub 2016 Feb 29.

27.

Use of Extrathoracic Deposition Models for Patient-Specific Dose Estimation during Inhaler Design.

Carrigy NB, Martin AR, Finlay WH.

Curr Pharm Des. 2015;21(27):3984-92. Review.

PMID:
26290196
28.

Simulation of muscle and adipose tissue deformation in the passive human pharynx.

Carrigy NB, Carey JP, Martin AR, Remmers JE, Zareian A, Topor Z, Grosse J, Noga M, Finlay WH.

Comput Methods Biomech Biomed Engin. 2016;19(7):780-8. doi: 10.1080/10255842.2015.1062477. Epub 2015 Jul 27.

PMID:
26213804
29.

Validation of airway resistance models for predicting pressure loss through anatomically realistic conducting airway replicas of adults and children.

Borojeni AA, Noga ML, Martin AR, Finlay WH.

J Biomech. 2015 Jul 16;48(10):1988-96. doi: 10.1016/j.jbiomech.2015.03.035. Epub 2015 Apr 7.

PMID:
25912661
30.

An Apparatus to Deliver Mannitol Powder for Bronchial Provocation in Children Under Six Years Old.

Tang P, Leung SS, Hor E, Ruzycki CA, Carrigy NB, Finlay WH, Brannan JD, Devadason S, Anderson SD, Sly PD, Samnick K, Chan HK.

J Aerosol Med Pulm Drug Deliv. 2015 Dec;28(6):452-61. doi: 10.1089/jamp.2015.1208. Epub 2015 Apr 6.

PMID:
25844950
31.

Nebulizers for drug delivery to the lungs.

Martin AR, Finlay WH.

Expert Opin Drug Deliv. 2015 Jun;12(6):889-900. doi: 10.1517/17425247.2015.995087. Epub 2014 Dec 23. Review.

PMID:
25534396
32.

Understanding pressurized metered dose inhaler performance.

Ivey JW, Vehring R, Finlay WH.

Expert Opin Drug Deliv. 2015 Jun;12(6):901-16. doi: 10.1517/17425247.2015.984683. Epub 2014 Dec 13. Review.

PMID:
25496601
33.

Performance of pressurized metered-dose inhalers at extreme temperature conditions.

Morin CMD, Ivey JW, Titosky JTF, Suderman JD, Olfert JS, Vehring R, Finlay WH.

J Pharm Sci. 2014 Nov;103(11):3553-3559. doi: 10.1002/jps.24145. Epub 2014 Sep 22.

PMID:
25252183
34.

The effect of altitude on inhaler performance.

Titosky JTF, Morin CMD, Suderman JD, Olfert JS, Finlay WH, Vehring R.

J Pharm Sci. 2014 Jul;103(7):2116-2124. doi: 10.1002/jps.24032. Epub 2014 Jun 2.

PMID:
24890630
35.

Pediatric in vitro and in silico models of deposition via oral and nasal inhalation.

Carrigy NB, Ruzycki CA, Golshahi L, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2014 Jun;27(3):149-69. doi: 10.1089/jamp.2013.1075. Review.

PMID:
24870701
36.

Aerosol phage therapy efficacy in Burkholderia cepacia complex respiratory infections.

Semler DD, Goudie AD, Finlay WH, Dennis JJ.

Antimicrob Agents Chemother. 2014 Jul;58(7):4005-13. doi: 10.1128/AAC.02388-13. Epub 2014 May 5.

37.

Effect of electrostatic charge on deposition of uniformly charged monodisperse particles in the nasal extrathoracic airways of an infant.

Azhdarzadeh M, Olfert JS, Vehring R, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2015 Feb;28(1):30-4. doi: 10.1089/jamp.2013.1118. Epub 2014 Apr 1.

PMID:
24689985
38.

A correlation equation for the mass median aerodynamic diameter of the aerosol emitted by solution metered dose inhalers.

Ivey JW, Lewis D, Church T, Finlay WH, Vehring R.

Int J Pharm. 2014 Apr 25;465(1-2):18-24. doi: 10.1016/j.ijpharm.2014.01.039. Epub 2014 Feb 11.

PMID:
24524827
39.

Comparison of in vitro deposition of pharmaceutical aerosols in an idealized child throat with in vivo deposition in the upper respiratory tract of children.

Ruzycki CA, Golshahi L, Vehring R, Finlay WH.

Pharm Res. 2014 Jun;31(6):1525-35. doi: 10.1007/s11095-013-1258-2. Epub 2014 Jan 7.

PMID:
24395403
40.

Manufacturing and device options for the delivery of biotherapeutics.

Hoe S, Boraey MA, Ivey JW, Finlay WH, Vehring R.

J Aerosol Med Pulm Drug Deliv. 2014 Oct;27(5):315-28. doi: 10.1089/jamp.2013.1090. Epub 2013 Dec 3. Review.

PMID:
24299502
41.

Effect of facial material softness and applied force on face mask dead volume, face mask seal, and inhaled corticosteroid delivery through an idealized infant replica.

Carrigy NB, O'Reilly C, Schmitt J, Noga M, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2014 Aug;27(4):290-8. doi: 10.1089/jamp.2013.1087. Epub 2013 Nov 12.

PMID:
24219815
42.

Use of a fundamental approach to spray-drying formulation design to facilitate the development of multi-component dry powder aerosols for respiratory drug delivery.

Hoe S, Ivey JW, Boraey MA, Shamsaddini-Shahrbabak A, Javaheri E, Matinkhoo S, Finlay WH, Vehring R.

Pharm Res. 2014 Feb;31(2):449-65. doi: 10.1007/s11095-013-1174-5. Epub 2013 Aug 23.

PMID:
23974958
43.

Topical contrast agents to improve soft-tissue contrast in the upper airway using cone beam CT: a pilot study.

Alsufyani NA, Noga ML, Finlay WH, Major PW.

Dentomaxillofac Radiol. 2013;42(7):20130022. doi: 10.1259/dmfr.20130022. Epub 2013 Apr 26.

44.

Respirable bacteriophages for the treatment of bacterial lung infections.

Hoe S, Semler DD, Goudie AD, Lynch KH, Matinkhoo S, Finlay WH, Dennis JJ, Vehring R.

J Aerosol Med Pulm Drug Deliv. 2013 Dec;26(6):317-35. doi: 10.1089/jamp.2012.1001. Epub 2013 Apr 18. Review.

PMID:
23597003
45.

An in vitro study on the deposition of micrometer-sized particles in the extrathoracic airways of adults during tidal oral breathing.

Golshahi L, Noga ML, Vehring R, Finlay WH.

Ann Biomed Eng. 2013 May;41(5):979-89. doi: 10.1007/s10439-013-0747-0. Epub 2013 Jan 29.

PMID:
23358802
46.

The use of computational fluid dynamics in inhaler design.

Ruzycki CA, Javaheri E, Finlay WH.

Expert Opin Drug Deliv. 2013 Mar;10(3):307-23. doi: 10.1517/17425247.2013.753053. Epub 2013 Jan 7. Review.

PMID:
23289401
47.

In vitro investigation of the effect of ambient humidity on regional delivered dose with solution and suspension MDIs.

Shemirani FM, Hoe S, Lewis D, Church T, Vehring R, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2013 Aug;26(4):215-22. doi: 10.1089/jamp.2012.0991. Epub 2012 Oct 24.

PMID:
23094687
48.

Distribution of effervescent inhalable nanoparticles after pulmonary delivery: an in vivo study.

Al-Hallak MH, Sarfraz MK, Azarmi S, Roa WH, Finlay WH, Rouleau C, Löbenberg R.

Ther Deliv. 2012 Jun;3(6):725-34.

PMID:
22838068
49.

Pulmonary delivery of inhalable nanoparticles: dry powder inhalers.

Al-Hallak MH, Sarfraz MK, Azarmi S, Roa WH, Finlay WH, Löbenberg R.

Ther Deliv. 2011 Oct;2(10):1313-24. Review.

PMID:
22826885
50.

Simulation of enhanced deposition due to magnetic field alignment of ellipsoidal particles in a lung bifurcation.

Martinez RC, Roshchenko A, Minev P, Finlay WH.

J Aerosol Med Pulm Drug Deliv. 2013 Feb;26(1):31-40. doi: 10.1089/jamp.2011.0921. Epub 2012 May 2.

PMID:
22551082

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