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Items: 1 to 50 of 180

1.

AZD7648 is a potent and selective DNA-PK inhibitor that enhances radiation, chemotherapy and olaparib activity.

Fok JHL, Ramos-Montoya A, Vazquez-Chantada M, Wijnhoven PWG, Follia V, James N, Farrington PM, Karmokar A, Willis SE, Cairns J, Nikkilä J, Beattie D, Lamont GM, Finlay MRV, Wilson J, Smith A, O'Connor LO, Ling S, Fawell SE, O'Connor MJ, Hollingsworth SJ, Dean E, Goldberg FW, Davies BR, Cadogan EB.

Nat Commun. 2019 Nov 7;10(1):5065. doi: 10.1038/s41467-019-12836-9.

PMID:
31699977
2.

Selective DNA-PKcs inhibition extends the therapeutic index of localized radiotherapy and chemotherapy.

Willoughby CE, Jiang Y, Thomas HD, Willmore E, Kyle S, Wittner A, Phillips N, Zhao Y, Tudhope SJ, Prendergast L, Junge G, Madia Lourenco L, Finlay MRV, Turner P, Munck JM, Griffin RJ, Rennison T, Pickles J, Cano C, Newell DR, Reeves HL, Ryan AJ, Wedge SR.

J Clin Invest. 2019 Oct 3. pii: 127483. doi: 10.1172/JCI127483. [Epub ahead of print]

3.

A nurse-led implantable loop recorder service is safe and cost effective.

Lim WY, Papageorgiou N, Sukumar SM, Alexiou S, Srinivasan NT, Monkhouse C, Daw H, Caldeira H, Harvie H, Kuriakose J, Baca M, Ahsan SY, Chow AW, Hunter RJ, Finlay M, Lambiase PD, Schilling RJ, Earley MJ, Providencia R.

J Cardiovasc Electrophysiol. 2019 Oct 2. doi: 10.1111/jce.14206. [Epub ahead of print]

PMID:
31578806
4.

STAR mapping method to identify driving sites in persistent atrial fibrillation: Application through sequential mapping.

Honarbakhsh S, Schilling RJ, Finlay M, Keating E, Ullah W, Hunter RJ.

J Cardiovasc Electrophysiol. 2019 Sep 25. doi: 10.1111/jce.14201. [Epub ahead of print]

PMID:
31552697
5.

Full blood count as potential predictor of outcomes in patients undergoing cardiac resynchronization therapy.

Papageorgiou N, Falconer D, Ioannou A, Wongwarawipat T, Barra S, Tousoulis D, Lim WY, Khan FZ, Ahsan S, Muthumala A, Hunter RJ, Finlay M, Creta A, Rowland E, Lowe M, Segal OR, Schilling RJ, Lambiase PD, Chow AW, Providência R.

Sci Rep. 2019 Sep 10;9(1):13016. doi: 10.1038/s41598-019-49659-z.

6.

Fluoroscopy guided axillary vein access versus cephalic vein access in pacemaker and defibrillator implantation: Randomized clinical trial of efficacy and safety.

Creta A, Providência R, Finlay M.

J Cardiovasc Electrophysiol. 2019 Oct;30(10):2183. doi: 10.1111/jce.14115. Epub 2019 Aug 21. No abstract available.

PMID:
31433091
7.

Ablation in Persistent Atrial Fibrillation Using Stochastic Trajectory Analysis of Ranked Signals (STAR) Mapping Method.

Honarbakhsh S, Hunter RJ, Ullah W, Keating E, Finlay M, Schilling RJ.

JACC Clin Electrophysiol. 2019 Jul;5(7):817-829. doi: 10.1016/j.jacep.2019.04.007. Epub 2019 May 8.

8.

Autonomic modulation of the electrical substrate in mice haploinsufficient for cardiac sodium channels: a model of the Brugada syndrome.

Finlay M, Bhar-Amato J, Ng KE, Santos D, Orini M, Vyas V, Taggart P, Grace AA, Huang CL, Lambiase PD, Tinker A.

Am J Physiol Cell Physiol. 2019 Sep 1;317(3):C576-C583. doi: 10.1152/ajpcell.00028.2019. Epub 2019 Jul 10.

PMID:
31291141
9.

Discovery of a Thiadiazole-Pyridazine-Based Allosteric Glutaminase 1 Inhibitor Series That Demonstrates Oral Bioavailability and Activity in Tumor Xenograft Models.

Finlay MRV, Anderton M, Bailey A, Boyd S, Brookfield J, Cairnduff C, Charles M, Cheasty A, Critchlow SE, Culshaw J, Ekwuru T, Hollingsworth I, Jones N, Leroux F, Littleson M, McCarron H, McKelvie J, Mooney L, Nissink JWM, Perkins D, Powell S, Quesada MJ, Raubo P, Sabin V, Smith J, Smith PD, Stark A, Ting A, Wang P, Wilson Z, Winter-Holt JJ, Wood JM, Wrigley GL, Yu G, Zhang P.

J Med Chem. 2019 Jul 25;62(14):6540-6560. doi: 10.1021/acs.jmedchem.9b00260. Epub 2019 Jul 16.

PMID:
31199640
10.

Differentially expressed genes for atrial fibrillation identified by RNA sequencing from paired human left and right atrial appendages.

Thomas AM, Cabrera CP, Finlay M, Lall K, Nobles M, Schilling RJ, Wood K, Mein CA, Barnes MR, Munroe PB, Tinker A.

Physiol Genomics. 2019 Aug 1;51(8):323-332. doi: 10.1152/physiolgenomics.00012.2019. Epub 2019 Jun 7.

11.

Simultaneous Comparison of Electrocardiographic Imaging and Epicardial Contact Mapping in Structural Heart Disease.

Graham AJ, Orini M, Zacur E, Dhillon G, Daw H, Srinivasan NT, Lane JD, Cambridge A, Garcia J, O'Reilly NJ, Whittaker-Axon S, Taggart P, Lowe M, Finlay M, Earley MJ, Chow A, Sporton S, Dhinoja M, Schilling RJ, Hunter RJ, Lambiase PD.

Circ Arrhythm Electrophysiol. 2019 Apr;12(4):e007120. doi: 10.1161/CIRCEP.118.007120.

PMID:
30947511
12.

All-Optical Rotational Ultrasound Imaging.

Colchester RJ, Little C, Dwyer G, Noimark S, Alles EJ, Zhang EZ, Loder CD, Parkin IP, Papakonstantinou I, Beard PC, Finlay MC, Rakhit RD, Desjardins AE.

Sci Rep. 2019 Apr 3;9(1):5576. doi: 10.1038/s41598-019-41970-z.

13.

Dynamic physiological temperature and pressure sensing with phase-resolved low-coherence interferometry.

Coote JM, Alles EJ, Noimark S, Mosse CA, Little CD, Loder CD, David AL, Rakhit RD, Finlay MC, Desjardins AE.

Opt Express. 2019 Feb 18;27(4):5641-5654. doi: 10.1364/OE.27.005641.

PMID:
30876162
14.

The impact of virtual arrhythmia clinics following catheter ablation for atrial fibrillation.

Manimaran M, Das D, Martinez P, Schwartz R, Schilling R, Finlay M.

Eur Heart J Qual Care Clin Outcomes. 2019 Jul 1;5(3):272-273. doi: 10.1093/ehjqcco/qcz011. No abstract available.

PMID:
30847488
15.

Development, in vitro validation and human application of a novel method to identify arrhythmia mechanisms: The stochastic trajectory analysis of ranked signals mapping method.

Honarbakhsh S, Hunter RJ, Finlay M, Ullah W, Keating E, Tinker A, Schilling RJ.

J Cardiovasc Electrophysiol. 2019 May;30(5):691-701. doi: 10.1111/jce.13882. Epub 2019 Mar 5.

PMID:
30801836
16.

Procedural and quality assessment data on catheter ablation for fascicular ventricular tachycardia.

Creta A, Chow AW, Sporton S, Finlay M, Papageorgiou N, Honarbakhsh S, Dhillon G, Graham A, Patel KH, Dhinoja M, Earley MJ, Hunter RJ, Lowe M, Rowland E, Segal OR, Calabrese V, Ricciardi D, Lambiase PD, Schilling RJ, Providência R.

Data Brief. 2018 Nov 13;21:2376-2378. doi: 10.1016/j.dib.2018.11.027. eCollection 2018 Dec.

17.

Catheter ablation for fascicular ventricular tachycardia: A systematic review.

Creta A, Chow AW, Sporton S, Finlay M, Papageorgiou N, Honarbakhsh S, Dhillon G, Graham A, Patel KHK, Dhinoja M, Earley MJ, Hunter RJ, Lowe M, Rowland E, Segal OR, Calabrese V, Ricciardi D, Lambiase PD, Schilling RJ, Providência R.

Int J Cardiol. 2019 Feb 1;276:136-148. doi: 10.1016/j.ijcard.2018.10.080. Epub 2018 Oct 25.

PMID:
30463682
18.

A novel technique for performing transseptal puncture guided by a non-fluoroscopic 3D mapping system.

Sawhney V, Breitenstein A, Watts T, Garcia J, Finlay M, Lowe M, Hunter R, Earley MJ, Schilling RJ, Sporton S, Dhinoja M.

Pacing Clin Electrophysiol. 2019 Jan;42(1):4-12. doi: 10.1111/pace.13541. Epub 2018 Nov 28.

PMID:
30397922
19.

Left atrial scarring and conduction velocity dynamics: Rate dependent conduction slowing predicts sites of localized reentrant atrial tachycardias.

Honarbakhsh S, Schilling RJ, Orini M, Providencia R, Finlay M, Keating E, Lambiase PD, Chow A, Earley MJ, Sporton S, Hunter RJ.

Int J Cardiol. 2019 Mar 1;278:114-119. doi: 10.1016/j.ijcard.2018.10.072. Epub 2018 Oct 24.

PMID:
30391065
20.

Physical Response to Pad- and Bag-Based Boxing-Specific Training Modalities.

Finlay MJ, Greig M, McCarthy J, Page RM.

J Strength Cond Res. 2018 Oct 24. doi: 10.1519/JSC.0000000000002928. [Epub ahead of print]

PMID:
30358696
21.

Pharmacological Modulation of Right Ventricular Endocardial-Epicardial Gradients in Brugada Syndrome.

Bhar-Amato J, Finlay M, Santos D, Orini M, Chaubey S, Vyas V, Taggart P, Grace AA, Huang CL, Ben Simon R, Tinker A, Lambiase PD.

Circ Arrhythm Electrophysiol. 2018 Sep;11(9):e006330. doi: 10.1161/CIRCEP.118.006330.

PMID:
30354290
22.

It Does Take Two to Tango: An Applied Conversation Analysis of Interactions between a Psychiatrist and Service-Users Discussing Medication.

Kaminskiy E, Finlay M.

Health Commun. 2019 Nov;34(13):1628-1636. doi: 10.1080/10410236.2018.1517633. Epub 2018 Sep 12.

PMID:
30207485
23.

Three-Dimensional Ultrasonic Needle Tip Tracking with a Fiber-Optic Ultrasound Receiver.

Xia W, West SJ, Finlay MC, Pratt R, Mathews S, Mari JM, Ourselin S, David AL, Desjardins AE.

J Vis Exp. 2018 Aug 21;(138). doi: 10.3791/57207.

24.

Through-needle all-optical ultrasound imaging in vivo: a preclinical swine study.

Finlay MC, Mosse CA, Colchester RJ, Noimark S, Zhang EZ, Ourselin S, Beard PC, Schilling RJ, Parkin IP, Papakonstantinou I, Desjardins AE.

Light Sci Appl. 2017 Dec 1;6(12):e17103. doi: 10.1038/lsa.2017.103. eCollection 2017 Dec.

25.

All-optical dual photoacoustic and optical coherence tomography intravascular probe.

Mathews SJ, Little C, Loder CD, Rakhit RD, Xia W, Zhang EZ, Beard PC, Finlay MC, Desjardins AE.

Photoacoustics. 2018 Jul 24;11:65-70. doi: 10.1016/j.pacs.2018.07.002. eCollection 2018 Sep.

26.

Comparison of a high throughput day case atrial fibrillation ablation service in a local hospital with standard regional tertiary cardiac centre care.

Opel A, Mansell J, Butler A, Schwartz R, Fannon M, Finlay M, Hunter RJ, Schilling RJ.

Europace. 2019 Mar 1;21(3):440-444. doi: 10.1093/europace/euy153.

PMID:
30085050
27.

Structural remodeling and conduction velocity dynamics in the human left atrium: Relationship with reentrant mechanisms sustaining atrial fibrillation.

Honarbakhsh S, Schilling RJ, Orini M, Providencia R, Keating E, Finlay M, Sporton S, Chow A, Earley MJ, Lambiase PD, Hunter RJ.

Heart Rhythm. 2019 Jan;16(1):18-25. doi: 10.1016/j.hrthm.2018.07.019. Epub 2018 Jul 17.

28.

Impact of attributed audit on procedural performance in cardiac electrophysiology catheter laboratory.

Sawhney V, Volkova E, Shaukat M, Khan F, Segal O, Ahsan S, Chow A, Ezzat V, Finlay M, Lambiase P, Lowe M, Dhinoja M, Sporton S, Earley MJ, Hunter RJ, Schilling RJ.

J Interv Card Electrophysiol. 2018 Jun 1. doi: 10.1007/s10840-018-0383-6. [Epub ahead of print]

PMID:
29858762
29.

Ablation Index and Surround Flow Catheter Irrigation: Impedance-Based Appraisal in Clinical Ablation.

Ullah W, Hunter RJ, Finlay MC, McLean A, Dhinoja MB, Sporton S, Earley MJ, Schilling RJ.

JACC Clin Electrophysiol. 2017 Oct;3(10):1080-1088. doi: 10.1016/j.jacep.2017.03.011. Epub 2017 Jun 28.

30.

Engagement in online pain self-management improves pain in adults on medication-assisted behavioral treatment for opioid use disorders.

Wilson M, Finlay M, Orr M, Barbosa-Leiker C, Sherazi N, Roberts MLA, Layton M, Roll JM.

Addict Behav. 2018 Nov;86:130-137. doi: 10.1016/j.addbeh.2018.04.019. Epub 2018 Apr 27.

PMID:
29731244
31.

ATP-sensitive potassium channels in the sinoatrial node contribute to heart rate control and adaptation to hypoxia.

Aziz Q, Finlay M, Montaigne D, Ojake L, Li Y, Anderson N, Ludwig A, Tinker A.

J Biol Chem. 2018 Jun 8;293(23):8912-8921. doi: 10.1074/jbc.RA118.002775. Epub 2018 Apr 17.

32.

Quantifying the Physical Response to a Contemporary Amateur Boxing Simulation.

Finlay MJ, Greig M, Page RM.

J Strength Cond Res. 2018 Apr;32(4):1005-1012. doi: 10.1519/JSC.0000000000001926.

PMID:
29570596
33.

Pilot investigation: randomized-controlled analog trial for alcohol and tobacco smoking co-addiction using contingency management.

Orr MF, Lederhos Smith C, Finlay M, Martin SC, Brooks O, Oluwoye OA, Leickly E, McDonell M, Burduli E, Barbosa-Leiker C, Layton M, Roll JM, McPherson SM.

Behav Pharmacol. 2018 Aug;29(5):462-468. doi: 10.1097/FBP.0000000000000379.

34.

Antitumor Activity of Osimertinib, an Irreversible Mutant-Selective EGFR Tyrosine Kinase Inhibitor, in NSCLC Harboring EGFR Exon 20 Insertions.

Floc'h N, Martin MJ, Riess JW, Orme JP, Staniszewska AD, Ménard L, Cuomo ME, O'Neill DJ, Ward RA, Finlay MRV, McKerrecher D, Cheng M, Vang DP, Burich RA, Keck JG, Gandara DR, Mack PC, Cross DAE.

Mol Cancer Ther. 2018 May;17(5):885-896. doi: 10.1158/1535-7163.MCT-17-0758. Epub 2018 Feb 26.

35.

Erratum to "The contribution of pathways initiated via the Gq\11 G-protein family to atrial fibrillation" [Pharmacol. Res. 105 (2016) 54-61].

Tinker A, Finlay M, Nobles M, Opel A.

Pharmacol Res. 2018 Mar;129:544. doi: 10.1016/j.phrs.2018.02.019. No abstract available.

PMID:
29482824
36.

Use of leadless pacemakers in Europe: results of the European Heart Rhythm Association survey.

Boveda S, Lenarczyk R, Haugaa KH, Iliodromitis K, Finlay M, Lane D, Prinzen FW, Dagres N.

Europace. 2018 Mar 1;20(3):555-559. doi: 10.1093/europace/eux381. Erratum in: Europace. 2018 Mar 1;20(3):554.

PMID:
29360974
37.

Mutations in SUFU and PTCH1 genes may cause different cutaneous cancer predisposition syndromes: similar, but not the same.

Huq AJ, Walsh M, Rajagopalan B, Finlay M, Trainer AH, Bonnet F, Sevenet N, Winship IM.

Fam Cancer. 2018 Oct;17(4):601-606. doi: 10.1007/s10689-018-0073-7.

PMID:
29356994
38.

Anatomically realistic ultrasound phantoms using gel wax with 3D printed moulds.

Maneas E, Xia W, Nikitichev DI, Daher B, Manimaran M, Wong RYJ, Chang CW, Rahmani B, Capelli C, Schievano S, Burriesci G, Ourselin S, David AL, Finlay MC, West SJ, Vercauteren T, Desjardins AE.

Phys Med Biol. 2018 Jan 5;63(1):015033. doi: 10.1088/1361-6560/aa9e2c.

39.

Multi-organ vaso-occlusive disease: Buerger's or Kohlmeier-Degos disease?

Choo SZ, Simpson I, Finlay MJ, Mulley WR.

Pathology. 2017 Dec;49(7):798-801. doi: 10.1016/j.pathol.2017.06.008. Epub 2017 Oct 31. No abstract available.

PMID:
29096880
40.

Ultrasonic Needle Tracking with a Fibre-Optic Ultrasound Transmitter for Guidance of Minimally Invasive Fetal Surgery.

Xia W, Noimark S, Ourselin S, West SJ, Finlay MC, David AL, Desjardins AE.

Med Image Comput Comput Assist Interv. 2017 Sep;10434:637-645. doi: 10.1007/978-3-319-66185-8_72. Epub 2017 Sep 4.

41.

Panoramic atrial mapping with basket catheters: A quantitative analysis to optimize practice, patient selection, and catheter choice.

Honarbakhsh S, Schilling RJ, Providência R, Dhillon G, Sawhney V, Martin CA, Keating E, Finlay M, Ahsan S, Chow A, Earley MJ, Hunter RJ.

J Cardiovasc Electrophysiol. 2017 Dec;28(12):1423-1432. doi: 10.1111/jce.13331. Epub 2017 Sep 26.

PMID:
28862787
42.

The perfect storm.

Ruderman I, Finlay M, Barbour T.

Kidney Int. 2017 Jul;92(1):267. doi: 10.1016/j.kint.2017.03.049. No abstract available.

PMID:
28646996
43.

Looking beyond the imaging plane: 3D needle tracking with a linear array ultrasound probe.

Xia W, West SJ, Finlay MC, Mari JM, Ourselin S, David AL, Desjardins AE.

Sci Rep. 2017 Jun 16;7(1):3674. doi: 10.1038/s41598-017-03886-4.

44.

The structure-guided discovery of osimertinib: the first U.S. FDA approved mutant selective inhibitor of EGFR T790M.

Butterworth S, Cross DAE, Finlay MRV, Ward RA, Waring MJ.

Medchemcomm. 2017 May 10;8(5):820-822. doi: 10.1039/c7md90012k. eCollection 2017 May 1.

45.

The control of cardiac ventricular excitability by autonomic pathways.

Finlay M, Harmer SC, Tinker A.

Pharmacol Ther. 2017 Jun;174:97-111. doi: 10.1016/j.pharmthera.2017.02.023. Epub 2017 Feb 14. Review.

PMID:
28223225
46.

Durable remission of C3 glomerulonephritis with mycophenolate mofetil.

Lioufas N, Finlay M, Barbour T.

Nephrology (Carlton). 2017 Feb;22 Suppl 1:36-39. doi: 10.1111/nep.12939. Review.

PMID:
28176473
47.

Validation of a High-Fidelity Electrophysiology Simulator and Development of a Proficiency-Based Simulator Training Program.

Ullah W, Hunter RJ, Finlay M, Earley MJ, McLean A, Marazzi R, De Ponti R, Schilling RJ.

Simul Healthc. 2017 Feb;12(1):41-46. doi: 10.1097/SIH.0000000000000197.

PMID:
28146452
48.

Panoramic characterization of endocardial left atrial activation during human persistent AF: Insights from non-contact mapping.

Lee G, McLellan AJ, Hunter RJ, Lovell MJ, Finlay M, Ullah W, Dhinoja MB, Sporton S, Earley MJ, Schilling RJ.

Int J Cardiol. 2017 Feb 1;228:406-411. doi: 10.1016/j.ijcard.2016.11.085. Epub 2016 Nov 9.

PMID:
27870970
49.

A propensity matched case-control study comparing efficacy, safety and costs of the subcutaneous vs. transvenous implantable cardioverter defibrillator.

Honarbakhsh S, Providencia R, Srinivasan N, Ahsan S, Lowe M, Rowland E, Hunter RJ, Finlay M, Segal O, Earley MJ, Chow A, Schilling RJ, Lambiase PD.

Int J Cardiol. 2017 Feb 1;228:280-285. doi: 10.1016/j.ijcard.2016.11.017. Epub 2016 Nov 7.

PMID:
27865198
50.

Medium-term outcomes of idiopathic ventricular fibrillation survivors and family screening: a multicentre experience.

Honarbakhsh S, Srinivasan N, Kirkby C, Firman E, Tobin L, Finlay M, Hunter RJ, Murphy C, Lowe MD, Schilling RJ, Lambiase PD.

Europace. 2017 Nov 1;19(11):1874-1880. doi: 10.1093/europace/euw251.

PMID:
27738067

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