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Items: 1 to 50 of 595

1.

Prion acute synaptotoxicity is largely driven by protease-resistant PrPSc species.

Foliaki ST, Lewis V, Finkelstein DI, Lawson V, Coleman HA, Senesi M, Islam AMT, Chen F, Sarros S, Roberts B, Adlard PA, Collins SJ.

PLoS Pathog. 2018 Aug 8;14(8):e1007214. doi: 10.1371/journal.ppat.1007214. [Epub ahead of print]

2.

High-resolution transcriptional dissection of in vivo Atoh1-mediated hair cell conversion in mature cochleae identifies Isl1 as a co-reprogramming factor.

Yamashita T, Zheng F, Finkelstein D, Kellard Z, Carter R, Rosencrance CD, Sugino K, Easton J, Gawad C, Zuo J.

PLoS Genet. 2018 Jul 31;14(7):e1007552. doi: 10.1371/journal.pgen.1007552. eCollection 2018 Jul.

3.

Type I Interferon Potentiates IgA Immunity to Respiratory Syncytial Virus Infection During Infancy.

Hijano DR, Siefker DT, Shrestha B, Jaligama S, Vu LD, Tillman H, Finkelstein D, Saravia J, You D, Cormier SA.

Sci Rep. 2018 Jul 23;8(1):11034. doi: 10.1038/s41598-018-29456-w.

4.

Modulating Protein Phosphatase 2A Rescues Disease Phenotype in Neurodegenerative Tauopathies.

McKenzie-Nickson S, Chan J, Perez K, Hung LW, Cheng L, Sedjahtera A, Gunawan L, Adlard PA, Hayne DJ, McInnes LE, Donnelly PS, Finkelstein DI, Hill AF, Barnham KJ.

ACS Chem Neurosci. 2018 Jul 3. doi: 10.1021/acschemneuro.8b00161. [Epub ahead of print]

PMID:
29920069
5.

Mouse medulloblastoma driven by CRISPR activation of cellular Myc.

Vo BT, Kwon JA, Li C, Finkelstein D, Xu B, Orr BA, Sherr CJ, Roussel MF.

Sci Rep. 2018 Jun 7;8(1):8733. doi: 10.1038/s41598-018-24956-1.

6.

ETV6-NTRK3 induces aggressive acute lymphoblastic leukemia highly sensitive to selective TRK inhibition.

Roberts KG, Janke LJ, Zhao Y, Seth A, Ma J, Finkelstein D, Smith S, Ebata K, Tuch BB, Hunger SP, Mullighan CG.

Blood. 2018 Jun 7. pii: blood-2018-05-849554. doi: 10.1182/blood-2018-05-849554. [Epub ahead of print] No abstract available.

PMID:
29880614
7.

Trehalose elevates brain zinc levels following controlled cortical impact in a mouse model of traumatic brain injury.

Portbury SD, Hare DJ, Bishop DP, Finkelstein DI, Doble PA, Adlard PA.

Metallomics. 2018 Jun 20;10(6):846-853. doi: 10.1039/c8mt00068a.

PMID:
29872801
8.

Efficacy of Anti-HER2 Agents in Combination With Adjuvant or Neoadjuvant Chemotherapy for Early and Locally Advanced HER2-Positive Breast Cancer Patients: A Network Meta-Analysis.

Debiasi M, Polanczyk CA, Ziegelmann P, Barrios C, Cao H, Dignam JJ, Goss P, Bychkovsky B, Finkelstein DM, Guindalini RS, Filho P, Albuquerque C, Reinert T, de Azambuja E, Olopade O.

Front Oncol. 2018 May 22;8:156. doi: 10.3389/fonc.2018.00156. eCollection 2018. Review.

9.

UMI-count modeling and differential expression analysis for single-cell RNA sequencing.

Chen W, Li Y, Easton J, Finkelstein D, Wu G, Chen X.

Genome Biol. 2018 May 31;19(1):70. doi: 10.1186/s13059-018-1438-9.

10.

The critical role that STAT3 plays in glioma-initiating cells: STAT3 addiction in glioma.

Ganguly D, Fan M, Yang CH, Zbytek B, Finkelstein D, Roussel MF, Pfeffer LM.

Oncotarget. 2018 Apr 24;9(31):22095-22112. doi: 10.18632/oncotarget.25188. eCollection 2018 Apr 24.

11.

Robotic surgery in public hospitals of Latin-America: a castle of sand?

Secin FP, Coelho R, Monzó Gardiner JI, Salcedo JGC, Puente R, Martínez L, Finkelstein D, Valero R, León A, Angeloni D, Rozanec J, Berger M, Cavazzola LT, Faria EF, Machado RD, Lott F, Campos F, Morales Montor JG, Moreno CS, Barrios HD.

World J Urol. 2018 Apr;36(4):595-601. doi: 10.1007/s00345-018-2227-5. Epub 2018 Feb 19.

PMID:
29459996
12.

Nfix Promotes Survival of Immature Hematopoietic Cells via Regulation of c-Mpl.

Hall T, Walker M, Ganuza M, Holmfeldt P, Bordas M, Kang G, Bi W, Palmer LE, Finkelstein D, McKinney-Freeman S.

Stem Cells. 2018 Jun;36(6):943-950. doi: 10.1002/stem.2800. Epub 2018 Feb 27.

PMID:
29430853
13.

Acute Neurotoxicity Models of Prion Disease.

T Islam AM, Adlard PA, Finkelstein DI, Lewis V, Biggi S, Biasini E, Collins SJ.

ACS Chem Neurosci. 2018 Mar 21;9(3):431-445. doi: 10.1021/acschemneuro.7b00517. Epub 2018 Feb 14.

PMID:
29393619
14.

PAX3-FOXO1 drives miR-486-5p and represses miR-221 contributing to pathogenesis of alveolar rhabdomyosarcoma.

Hanna JA, Garcia MR, Lardennois A, Leavey PJ, Maglic D, Fagnan A, Go JC, Roach J, Wang YD, Finkelstein D, Hatley ME.

Oncogene. 2018 Apr;37(15):1991-2007. doi: 10.1038/s41388-017-0081-3. Epub 2018 Jan 25.

15.

HNRNPH1 is required for rhabdomyosarcoma cell growth and survival.

Li Y, Bakke J, Finkelstein D, Zeng H, Wu J, Chen T.

Oncogenesis. 2018 Jan 24;7(1):9. doi: 10.1038/s41389-017-0024-4.

16.

The role of interleukin-2, all-trans retinoic acid, and natural killer cells: surveillance mechanisms in anti-GD2 antibody therapy in neuroblastoma.

Nguyen R, Houston J, Chan WK, Finkelstein D, Dyer MA.

Cancer Immunol Immunother. 2018 Apr;67(4):615-626. doi: 10.1007/s00262-017-2108-6. Epub 2018 Jan 11.

PMID:
29327110
17.

Hedgehog Pathway Drives Fusion-Negative Rhabdomyosarcoma Initiated From Non-myogenic Endothelial Progenitors.

Drummond CJ, Hanna JA, Garcia MR, Devine DJ, Heyrana AJ, Finkelstein D, Rehg JE, Hatley ME.

Cancer Cell. 2018 Jan 8;33(1):108-124.e5. doi: 10.1016/j.ccell.2017.12.001.

PMID:
29316425
18.

Acquisition of Cholangiocarcinoma Traits during Advanced Hepatocellular Carcinoma Development in Mice.

Li L, Qian M, Chen IH, Finkelstein D, Onar-Thomas A, Johnson M, Calabrese C, Bahrami A, López-Terrada DH, Yang JJ, Tao WA, Zhu L.

Am J Pathol. 2018 Mar;188(3):656-671. doi: 10.1016/j.ajpath.2017.11.013. Epub 2017 Dec 15.

PMID:
29248454
19.

Expressed Gene Fusions as Frequent Drivers of Poor Outcomes in Hormone Receptor-Positive Breast Cancer.

Matissek KJ, Onozato ML, Sun S, Zheng Z, Schultz A, Lee J, Patel K, Jerevall PL, Saladi SV, Macleay A, Tavallai M, Badovinac-Crnjevic T, Barrios C, Beşe N, Chan A, Chavarri-Guerra Y, Debiasi M, Demirdögen E, Egeli Ü, Gökgöz S, Gomez H, Liedke P, Tasdelen I, Tolunay S, Werutsky G, St Louis J, Horick N, Finkelstein DM, Le LP, Bardia A, Goss PE, Sgroi DC, Iafrate AJ, Ellisen LW.

Cancer Discov. 2018 Mar;8(3):336-353. doi: 10.1158/2159-8290.CD-17-0535. Epub 2017 Dec 14.

PMID:
29242214
20.

Promoting Children's Physical Activity in Low-Income Communities in Colorado: What Are the Barriers and Opportunities?

Finkelstein DM, Petersen DM, Schottenfeld LS.

Prev Chronic Dis. 2017 Dec 14;14:E134. doi: 10.5888/pcd14.170111.

21.

Hypoxia-induced upregulation of BMX kinase mediates therapeutic resistance in acute myeloid leukemia.

van Oosterwijk JG, Buelow DR, Drenberg CD, Vasilyeva A, Li L, Shi L, Wang YD, Finkelstein D, Shurtleff SA, Janke LJ, Pounds S, Rubnitz JE, Inaba H, Pabla N, Baker SD.

J Clin Invest. 2018 Jan 2;128(1):369-380. doi: 10.1172/JCI91893. Epub 2017 Dec 11.

22.

A pilot investigation of an iOS-based app for toilet training children with autism spectrum disorder.

Mruzek DW, McAleavey S, Loring WA, Butter E, Smith T, McDonnell E, Levato L, Aponte C, Travis RP, Aiello RE, Taylor CM, Wilkins JW, Corbett-Dick P, Finkelstein DM, York AM, Zanibbi K.

Autism. 2017 Dec 1:1362361317741741. doi: 10.1177/1362361317741741. [Epub ahead of print]

PMID:
29212345
23.

Modulation of Navitoclax Sensitivity by Dihydroartemisinin-Mediated MCL-1 Repression in BCR-ABL+ B-Lineage Acute Lymphoblastic Leukemia.

Budhraja A, Turnis ME, Churchman ML, Kothari A, Yang X, Xu H, Kaminska E, Panetta JC, Finkelstein D, Mullighan CG, Opferman JT.

Clin Cancer Res. 2017 Dec 15;23(24):7558-7568. doi: 10.1158/1078-0432.CCR-17-1231. Epub 2017 Oct 3.

PMID:
28974549
24.

Lifelong haematopoiesis is established by hundreds of precursors throughout mammalian ontogeny.

Ganuza M, Hall T, Finkelstein D, Chabot A, Kang G, McKinney-Freeman S.

Nat Cell Biol. 2017 Oct;19(10):1153-1163. doi: 10.1038/ncb3607. Epub 2017 Sep 18.

25.

Biallelic Dicer1 Loss Mediated by aP2-Cre Drives Angiosarcoma.

Hanna JA, Drummond CJ, Garcia MR, Go JC, Finkelstein D, Rehg JE, Hatley ME.

Cancer Res. 2017 Nov 15;77(22):6109-6118. doi: 10.1158/0008-5472.CAN-17-1262. Epub 2017 Sep 15.

PMID:
28916654
26.

Trehalose Improves Cognition in the Transgenic Tg2576 Mouse Model of Alzheimer's Disease.

Portbury SD, Hare DJ, Sgambelloni C, Perronnes K, Portbury AJ, Finkelstein DI, Adlard PA.

J Alzheimers Dis. 2017;60(2):549-560. doi: 10.3233/JAD-170322.

27.

Trehalose improves traumatic brain injury-induced cognitive impairment.

Portbury SD, Hare DJ, Finkelstein DI, Adlard PA.

PLoS One. 2017 Aug 24;12(8):e0183683. doi: 10.1371/journal.pone.0183683. eCollection 2017.

28.

Ventromorphins: A New Class of Small Molecule Activators of the Canonical BMP Signaling Pathway.

Genthe JR, Min J, Farmer DM, Shelat AA, Grenet JA, Lin W, Finkelstein D, Vrijens K, Chen T, Guy RK, Clements WK, Roussel MF.

ACS Chem Biol. 2017 Sep 15;12(9):2436-2447. doi: 10.1021/acschembio.7b00527. Epub 2017 Aug 29.

29.

The whole-genome landscape of medulloblastoma subtypes.

Northcott PA, Buchhalter I, Morrissy AS, Hovestadt V, Weischenfeldt J, Ehrenberger T, Gröbner S, Segura-Wang M, Zichner T, Rudneva VA, Warnatz HJ, Sidiropoulos N, Phillips AH, Schumacher S, Kleinheinz K, Waszak SM, Erkek S, Jones DTW, Worst BC, Kool M, Zapatka M, Jäger N, Chavez L, Hutter B, Bieg M, Paramasivam N, Heinold M, Gu Z, Ishaque N, Jäger-Schmidt C, Imbusch CD, Jugold A, Hübschmann D, Risch T, Amstislavskiy V, Gonzalez FGR, Weber UD, Wolf S, Robinson GW, Zhou X, Wu G, Finkelstein D, Liu Y, Cavalli FMG, Luu B, Ramaswamy V, Wu X, Koster J, Ryzhova M, Cho YJ, Pomeroy SL, Herold-Mende C, Schuhmann M, Ebinger M, Liau LM, Mora J, McLendon RE, Jabado N, Kumabe T, Chuah E, Ma Y, Moore RA, Mungall AJ, Mungall KL, Thiessen N, Tse K, Wong T, Jones SJM, Witt O, Milde T, Von Deimling A, Capper D, Korshunov A, Yaspo ML, Kriwacki R, Gajjar A, Zhang J, Beroukhim R, Fraenkel E, Korbel JO, Brors B, Schlesner M, Eils R, Marra MA, Pfister SM, Taylor MD, Lichter P.

Nature. 2017 Jul 19;547(7663):311-317. doi: 10.1038/nature22973.

30.

Histone H3G34R mutation causes replication stress, homologous recombination defects and genomic instability in S. pombe.

Yadav RK, Jablonowski CM, Fernandez AG, Lowe BR, Henry RA, Finkelstein D, Barnum KJ, Pidoux AL, Kuo YM, Huang J, O'Connell MJ, Andrews AJ, Onar-Thomas A, Allshire RC, Partridge JF.

Elife. 2017 Jul 18;6. pii: e27406. doi: 10.7554/eLife.27406.

31.

SNP-mediated disruption of CTCF binding at the IFITM3 promoter is associated with risk of severe influenza in humans.

Allen EK, Randolph AG, Bhangale T, Dogra P, Ohlson M, Oshansky CM, Zamora AE, Shannon JP, Finkelstein D, Dressen A, DeVincenzo J, Caniza M, Youngblood B, Rosenberger CM, Thomas PG.

Nat Med. 2017 Aug;23(8):975-983. doi: 10.1038/nm.4370. Epub 2017 Jul 17.

32.

The paralytic shellfish toxin, saxitoxin, enters the cytoplasm and induces apoptosis of oyster immune cells through a caspase-dependent pathway.

Abi-Khalil C, Finkelstein DS, Conejero G, Du Bois J, Destoumieux-Garzon D, Rolland JL.

Aquat Toxicol. 2017 Sep;190:133-141. doi: 10.1016/j.aquatox.2017.07.001. Epub 2017 Jul 8.

PMID:
28711010
33.

Identification of OAT1/OAT3 as Contributors to Cisplatin Toxicity.

Hu S, Leblanc AF, Gibson AA, Hong KW, Kim JY, Janke LJ, Li L, Vasilyeva A, Finkelstein DB, Sprowl JA, Sweet DH, Schlatter E, Ciarimboli G, Schellens J, Baker SD, Pabla N, Sparreboom A.

Clin Transl Sci. 2017 Sep;10(5):412-420. doi: 10.1111/cts.12480. Epub 2017 Jul 8.

34.

The novel compound PBT434 prevents iron mediated neurodegeneration and alpha-synuclein toxicity in multiple models of Parkinson's disease.

Finkelstein DI, Billings JL, Adlard PA, Ayton S, Sedjahtera A, Masters CL, Wilkins S, Shackleford DM, Charman SA, Bal W, Zawisza IA, Kurowska E, Gundlach AL, Ma S, Bush AI, Hare DJ, Doble PA, Crawford S, Gautier EC, Parsons J, Huggins P, Barnham KJ, Cherny RA.

Acta Neuropathol Commun. 2017 Jun 28;5(1):53. doi: 10.1186/s40478-017-0456-2.

35.

Excessive early-life dietary exposure: a potential source of elevated brain iron and a risk factor for Parkinson's disease.

Hare DJ, Cardoso BR, Raven EP, Double KL, Finkelstein DI, Szymlek-Gay EA, Biggs BA.

NPJ Parkinsons Dis. 2017 Jan 5;3:1. doi: 10.1038/s41531-016-0004-y. eCollection 2017.

36.

Evaluation of IFITM3 rs12252 Association With Severe Pediatric Influenza Infection.

Randolph AG, Yip WK, Allen EK, Rosenberger CM, Agan AA, Ash SA, Zhang Y, Bhangale TR, Finkelstein D, Cvijanovich NZ, Mourani PM, Hall MW, Su HC, Thomas PG; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators; Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators.

J Infect Dis. 2017 Jul 1;216(1):14-21. doi: 10.1093/infdis/jix242.

37.

Novel MYC-driven medulloblastoma models from multiple embryonic cerebellar cells.

Kawauchi D, Ogg RJ, Liu L, Shih DJH, Finkelstein D, Murphy BL, Rehg JE, Korshunov A, Calabrese C, Zindy F, Phoenix T, Kawaguchi Y, Gronych J, Gilbertson RJ, Lichter P, Gajjar A, Kool M, Northcott PA, Pfister SM, Roussel MF.

Oncogene. 2017 Sep 14;36(37):5231-5242. doi: 10.1038/onc.2017.110. Epub 2017 May 15.

38.

Analogues of desferrioxamine B designed to attenuate iron-mediated neurodegeneration: synthesis, characterisation and activity in the MPTP-mouse model of Parkinson's disease.

Gotsbacher MP, Telfer TJ, Witting PK, Double KL, Finkelstein DI, Codd R.

Metallomics. 2017 Jul 19;9(7):852-864. doi: 10.1039/c7mt00039a.

PMID:
28466891
39.

MYCN induces neuroblastoma in primary neural crest cells.

Olsen RR, Otero JH, García-López J, Wallace K, Finkelstein D, Rehg JE, Yin Z, Wang YD, Freeman KW.

Oncogene. 2017 Aug 31;36(35):5075-5082. doi: 10.1038/onc.2017.128. Epub 2017 May 1.

40.

In vivo prion models and the disconnection between transmissibility and neurotoxicity.

Senesi M, Lewis V, Kim JH, Adlard PA, Finkelstein DI, Collins SJ.

Ageing Res Rev. 2017 Jul;36:156-164. doi: 10.1016/j.arr.2017.03.007. Epub 2017 Apr 24. Review.

PMID:
28450269
41.

Inactivation of Ezh2 Upregulates Gfi1 and Drives Aggressive Myc-Driven Group 3 Medulloblastoma.

Vo BT, Li C, Morgan MA, Theurillat I, Finkelstein D, Wright S, Hyle J, Smith SMC, Fan Y, Wang YD, Wu G, Orr BA, Northcott PA, Shilatifard A, Sherr CJ, Roussel MF.

Cell Rep. 2017 Mar 21;18(12):2907-2917. doi: 10.1016/j.celrep.2017.02.073.

42.

Pramipexole restores depressed transmission in the ventral hippocampus following MPTP-lesion.

Castro-Hernández J, Adlard PA, Finkelstein DI.

Sci Rep. 2017 Mar 14;7:44426. doi: 10.1038/srep44426.

43.

Age modulates the injury-induced metallomic profile in the brain.

Portbury SD, Hare DJ, Sgambelloni CJ, Bishop DP, Finkelstein DI, Doble PA, Adlard PA.

Metallomics. 2017 Apr 19;9(4):402-410. doi: 10.1039/c6mt00260a.

PMID:
28170006
44.

Early Detection of Ovarian Cancer using the Risk of Ovarian Cancer Algorithm with Frequent CA125 Testing in Women at Increased Familial Risk - Combined Results from Two Screening Trials.

Skates SJ, Greene MH, Buys SS, Mai PL, Brown P, Piedmonte M, Rodriguez G, Schorge JO, Sherman M, Daly MB, Rutherford T, Brewster WR, O'Malley DM, Partridge E, Boggess J, Drescher CW, Isaacs C, Berchuck A, Domchek S, Davidson SA, Edwards R, Elg SA, Wakeley K, Phillips KA, Armstrong D, Horowitz I, Fabian CJ, Walker J, Sluss PM, Welch W, Minasian L, Horick NK, Kasten CH, Nayfield S, Alberts D, Finkelstein DM, Lu KH.

Clin Cancer Res. 2017 Jul 15;23(14):3628-3637. doi: 10.1158/1078-0432.CCR-15-2750. Epub 2017 Jan 31.

45.

Ferroptosis and cell death mechanisms in Parkinson's disease.

Guiney SJ, Adlard PA, Bush AI, Finkelstein DI, Ayton S.

Neurochem Int. 2017 Mar;104:34-48. doi: 10.1016/j.neuint.2017.01.004. Epub 2017 Jan 9. Review.

PMID:
28082232
46.

Real world patterns of care in HER2-overexpressing breast cancer: Results of a survey of TEACH clinical trial investigators in 2011.

Chavarri-Guerra Y, St Louis J, Bukowski A, Soto-Perez-de-Celis E, Liedke PER, Symecko H, Moy B, Higgins M, Finkelstein DM, Goss PE.

Breast. 2017 Feb;31:197-201. doi: 10.1016/j.breast.2016.11.014. Epub 2016 Nov 25.

PMID:
27894048
47.

Correction: Functional screen identifies regulators of murine hematopoietic stem cell repopulation.

Holmfeldt P, Ganuza M, Marathe H, He B, Hall T, Kang G, Moen J, Pardieck J, Saulsberry AC, Cico A, Gaut L, McGoldrick D, Finkelstein D, Tan K, McKinney-Freeman S.

J Exp Med. 2016 Oct 17;213(11):2525. Epub 2016 Sep 27. No abstract available.

48.

A randomized controlled trial of cognitive behavioral therapy for ADHD in medication-treated adolescents.

Sprich SE, Safren SA, Finkelstein D, Remmert JE, Hammerness P.

J Child Psychol Psychiatry. 2016 Nov;57(11):1218-1226. doi: 10.1111/jcpp.12549. Epub 2016 Mar 17.

49.

Physical and psychological health in rare cancer survivors.

Horick NK, Manful A, Lowery J, Domchek S, Moorman P, Griffin C, Visvanathan K, Isaacs C, Kinney AY, Finkelstein DM.

J Cancer Surviv. 2017 Feb;11(1):158-165. doi: 10.1007/s11764-016-0573-0. Epub 2016 Oct 19.

50.

Keratinocytes contribute intrinsically to psoriasis upon loss of Tnip1 function.

Ippagunta SK, Gangwar R, Finkelstein D, Vogel P, Pelletier S, Gingras S, Redecke V, Häcker H.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6162-E6171. Epub 2016 Sep 26.

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