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Items: 1 to 50 of 78

1.

Being Overweight or Obese and the Development of Asthma.

Lang JE, Bunnell HT, Hossain MJ, Wysocki T, Lima JJ, Finkel TH, Bacharier L, Dempsey A, Sarzynski L, Test M, Forrest CB.

Pediatrics. 2018 Dec;142(6). pii: e20182119. doi: 10.1542/peds.2018-2119.

PMID:
30478238
2.

Variants in CXCR4 associate with juvenile idiopathic arthritis susceptibility.

Finkel TH, Li J, Wei Z, Wang W, Zhang H, Behrens EM, Reuschel EL, Limou S, Wise C, Punaro M, Becker ML, Munro JE, Flatø B, Førre Ø, Thompson SD, Langefeld CD, Glass DN, Glessner JT, Kim CE, Frackelton E, Shivers DK, Thomas KA, Chiavacci RM, Hou C, Xu K, Snyder J, Qiu H, Mentch F, Wang K, Winkler CA, Lie BA, Ellis JA, Hakonarson H.

BMC Med Genet. 2016 Mar 22;17:24. doi: 10.1186/s12881-016-0285-3.

3.

Genetic sharing and heritability of paediatric age of onset autoimmune diseases.

Li YR, Zhao SD, Li J, Bradfield JP, Mohebnasab M, Steel L, Kobie J, Abrams DJ, Mentch FD, Glessner JT, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Li D, Maggadottir SM, Thomas KA, Qui H, Chiavacci RM, Kim CE, Wang F, Snyder J, Flatø B, Førre Ø, Denson LA, Thompson SD, Becker ML, Guthery SL, Latiano A, Perez E, Resnick E, Strisciuglio C, Staiano A, Miele E, Silverberg MS, Lie BA, Punaro M, Russell RK, Wilson DC, Dubinsky MC, Monos DS, Annese V, Munro JE, Wise C, Chapel H, Cunningham-Rundles C, Orange JS, Behrens EM, Sullivan KE, Kugathasan S, Griffiths AM, Satsangi J, Grant SFA, Sleiman PMA, Finkel TH, Polychronakos C, Baldassano RN, Luning Prak ET, Ellis JA, Li H, Keating BJ, Hakonarson H.

Nat Commun. 2015 Oct 9;6:8442. doi: 10.1038/ncomms9442.

4.

REDD1 Is Essential for Optimal T Cell Proliferation and Survival.

Reuschel EL, Wang J, Shivers DK, Muthumani K, Weiner DB, Ma Z, Finkel TH.

PLoS One. 2015 Aug 24;10(8):e0136323. doi: 10.1371/journal.pone.0136323. eCollection 2015.

5.

Meta-analysis of shared genetic architecture across ten pediatric autoimmune diseases.

Li YR, Li J, Zhao SD, Bradfield JP, Mentch FD, Maggadottir SM, Hou C, Abrams DJ, Chang D, Gao F, Guo Y, Wei Z, Connolly JJ, Cardinale CJ, Bakay M, Glessner JT, Li D, Kao C, Thomas KA, Qiu H, Chiavacci RM, Kim CE, Wang F, Snyder J, Richie MD, Flatø B, Førre Ø, Denson LA, Thompson SD, Becker ML, Guthery SL, Latiano A, Perez E, Resnick E, Russell RK, Wilson DC, Silverberg MS, Annese V, Lie BA, Punaro M, Dubinsky MC, Monos DS, Strisciuglio C, Staiano A, Miele E, Kugathasan S, Ellis JA, Munro JE, Sullivan KE, Wise CA, Chapel H, Cunningham-Rundles C, Grant SF, Orange JS, Sleiman PM, Behrens EM, Griffiths AM, Satsangi J, Finkel TH, Keinan A, Prak ET, Polychronakos C, Baldassano RN, Li H, Keating BJ, Hakonarson H.

Nat Med. 2015 Sep;21(9):1018-27. doi: 10.1038/nm.3933. Epub 2015 Aug 24.

6.

The association of PTPN22 rs2476601 with juvenile idiopathic arthritis is specific to females.

Chiaroni-Clarke RC, Li YR, Munro JE, Chavez RA, Scurrah KJ, Pezic A, Akikusa JD, Allen RC, Piper SE, Becker ML, Thompson SD, Lie BA, Flato B, Forre O, Punaro M, Wise C, Saffery R, Finkel TH, Hakonarson H, Ponsonby AL, Ellis JA.

Genes Immun. 2015 Oct;16(7):495-8. doi: 10.1038/gene.2015.32. Epub 2015 Aug 20.

PMID:
26291515
7.

Epistasis amongst PTPN2 and genes of the vitamin D pathway contributes to risk of juvenile idiopathic arthritis.

Ellis JA, Scurrah KJ, Li YR, Ponsonby AL, Chavez RA, Pezic A, Dwyer T, Akikusa JD, Allen RC, Becker ML, Thompson SD, Lie BA, Flatø B, Førre O, Punaro M, Wise C, Finkel TH, Hakonarson H, Munro JE.

J Steroid Biochem Mol Biol. 2015 Jan;145:113-20. doi: 10.1016/j.jsbmb.2014.10.012. Epub 2014 Oct 18.

PMID:
25460303
8.

Novel and enhanced anti-melanoma DNA vaccine targeting the tyrosinase protein inhibits myeloid-derived suppressor cells and tumor growth in a syngeneic prophylactic and therapeutic murine model.

Yan J, Tingey C, Lyde R, Gorham TC, Choo DK, Muthumani A, Myles D, Weiner LP, Kraynyak KA, Reuschel EL, Finkel TH, Kim JJ, Sardesai NY, Ugen KE, Muthumani K, Weiner DB.

Cancer Gene Ther. 2014 Dec;21(12):507-17. doi: 10.1038/cgt.2014.56. Epub 2014 Nov 14.

PMID:
25394503
9.

TCR triggering by pMHC ligands tethered on surfaces via poly(ethylene glycol) depends on polymer length.

Ma Z, LeBard DN, Loverde SM, Sharp KA, Klein ML, Discher DE, Finkel TH.

PLoS One. 2014 Nov 10;9(11):e112292. doi: 10.1371/journal.pone.0112292. eCollection 2014.

10.

The impact of Nucleofection® on the activation state of primary human CD4 T cells.

Zhang M, Ma Z, Selliah N, Weiss G, Genin A, Finkel TH, Cron RQ.

J Immunol Methods. 2014 Jun;408:123-31. doi: 10.1016/j.jim.2014.05.014. Epub 2014 Jun 5.

11.

Tumor necrosis factor receptor-associated factor 1 influences KRN/I-Ag7 mouse arthritis autoantibody production.

Cheng T, Choi Y, Finkel TH, Tsao PY, Ji MQ, Eisenberg RA.

J Clin Immunol. 2013 May;33(4):759-66. doi: 10.1007/s10875-013-9866-5. Epub 2013 Jan 26.

12.

Mechanical force in T cell receptor signal initiation.

Ma Z, Discher DE, Finkel TH.

Front Immunol. 2012 Jul 20;3:217. doi: 10.3389/fimmu.2012.00217. eCollection 2012. No abstract available.

13.

Glucocorticoid elevation of dexamethasone-induced gene 2 (Dig2/RTP801/REDD1) protein mediates autophagy in lymphocytes.

Molitoris JK, McColl KS, Swerdlow S, Matsuyama M, Lam M, Finkel TH, Matsuyama S, Distelhorst CW.

J Biol Chem. 2011 Aug 26;286(34):30181-9. doi: 10.1074/jbc.M111.245423. Epub 2011 Jul 6. Erratum in: J Biol Chem. 2011 Nov 11;286(45):39673.

14.

Enthesitis in an inception cohort of enthesitis-related arthritis.

Weiss PF, Klink AJ, Behrens EM, Sherry DD, Finkel TH, Feudtner C, Keren R.

Arthritis Care Res (Hoboken). 2011 Sep;63(9):1307-12. doi: 10.1002/acr.20508.

15.

Improved method of preparation of supported planar lipid bilayers as artificial membranes for antigen presentation.

Ma Z, Janmey PA, Sharp KA, Finkel TH.

Microsc Res Tech. 2011 Dec;74(12):1174-85. doi: 10.1002/jemt.21012. Epub 2011 May 11.

PMID:
21563272
16.

HIV-1 Vif promotes the G₁- to S-phase cell-cycle transition.

Wang J, Reuschel EL, Shackelford JM, Jeang L, Shivers DK, Diehl JA, Yu XF, Finkel TH.

Blood. 2011 Jan 27;117(4):1260-9. doi: 10.1182/blood-2010-06-289215. Epub 2010 Dec 13.

17.

T cell receptor triggering by force.

Ma Z, Finkel TH.

Trends Immunol. 2010 Jan;31(1):1-6. doi: 10.1016/j.it.2009.09.008.

18.

FOXP3 inhibits HIV-1 infection of CD4 T-cells via inhibition of LTR transcriptional activity.

Selliah N, Zhang M, White S, Zoltick P, Sawaya BE, Finkel TH, Cron RQ.

Virology. 2008 Nov 25;381(2):161-7. doi: 10.1016/j.virol.2008.08.033. Epub 2008 Oct 1.

19.

Association of the TRAF1-C5 locus on chromosome 9 with juvenile idiopathic arthritis.

Behrens EM, Finkel TH, Bradfield JP, Kim CE, Linton L, Casalunovo T, Frackelton EC, Santa E, Otieno FG, Glessner JT, Chiavacci RM, Grant SF, Hakonarson H.

Arthritis Rheum. 2008 Jul;58(7):2206-7. doi: 10.1002/art.23603. No abstract available.

20.

The HIV-1 Vif protein mediates degradation of Vpr and reduces Vpr-induced cell cycle arrest.

Wang J, Shackelford JM, Selliah N, Shivers DK, O'Neill E, Garcia JV, Muthumani K, Weiner D, Yu XF, Gabuzda D, Finkel TH.

DNA Cell Biol. 2008 May;27(5):267-77. doi: 10.1089/dna.2007.0707.

PMID:
18462066
21.

Surface-anchored monomeric agonist pMHCs alone trigger TCR with high sensitivity.

Ma Z, Sharp KA, Janmey PA, Finkel TH.

PLoS Biol. 2008 Feb;6(2):e43. doi: 10.1371/journal.pbio.0060043.

22.

Takayasu arteritis presenting as cerebral aneurysms in an 18 month old: A case report.

Weiss PF, Corao DA, Pollock AN, Finkel TH, Smith SE.

Pediatr Rheumatol Online J. 2008 Jan 31;6:4. doi: 10.1186/1546-0096-6-4.

23.

Evaluation of the presentation of systemic onset juvenile rheumatoid arthritis: data from the Pennsylvania Systemic Onset Juvenile Arthritis Registry (PASOJAR).

Behrens EM, Beukelman T, Gallo L, Spangler J, Rosenkranz M, Arkachaisri T, Ayala R, Groh B, Finkel TH, Cron RQ.

J Rheumatol. 2008 Feb;35(2):343-8. Epub 2007 Dec 15.

PMID:
18085728
24.

The receptor deformation model of TCR triggering.

Ma Z, Janmey PA, Finkel TH.

FASEB J. 2008 Apr;22(4):1002-8. Epub 2007 Nov 5.

25.

Complement receptor 3 ligation of dendritic cells suppresses their stimulatory capacity.

Behrens EM, Sriram U, Shivers DK, Gallucci M, Ma Z, Finkel TH, Gallucci S.

J Immunol. 2007 May 15;178(10):6268-79.

26.

The Vif accessory protein alters the cell cycle of human immunodeficiency virus type 1 infected cells.

Wang J, Shackelford JM, Casella CR, Shivers DK, Rapaport EL, Liu B, Yu XF, Finkel TH.

Virology. 2007 Mar 15;359(2):243-52. Epub 2006 Oct 23.

27.

Effective gene suppression using small interfering RNA in hard-to-transfect human T cells.

Yin J, Ma Z, Selliah N, Shivers DK, Cron RQ, Finkel TH.

J Immunol Methods. 2006 May 30;312(1-2):1-11. Epub 2006 Mar 24.

PMID:
16603179
28.

Treatment of pediatric localized scleroderma with methotrexate.

Fitch PG, Rettig P, Burnham JM, Finkel TH, Yan AC, Akin E, Cron RQ.

J Rheumatol. 2006 Mar;33(3):609-14.

PMID:
16511930
29.

Early growth response-1 is required for CD154 transcription.

Cron RQ, Bandyopadhyay R, Genin A, Brunner M, Kersh GJ, Yin J, Finkel TH, Crow MK.

J Immunol. 2006 Jan 15;176(2):811-8.

30.

Ligation of CD28 by its natural ligand CD86 in the absence of TCR stimulation induces lipid raft polarization in human CD4 T cells.

Kovacs B, Parry RV, Ma Z, Fan E, Shivers DK, Freiberg BA, Thomas AK, Rutherford R, Rumbley CA, Riley JL, Finkel TH.

J Immunol. 2005 Dec 15;175(12):7848-54.

31.

The gammac-cytokine regulated transcription factor, STAT5, increases HIV-1 production in primary CD4 T cells.

Selliah N, Zhang M, DeSimone D, Kim H, Brunner M, Ittenbach RF, Rui H, Cron RQ, Finkel TH.

Virology. 2006 Jan 20;344(2):283-91. Epub 2005 Nov 14.

32.

Extensive replicative capacity of human central memory T cells.

Maus MV, Kovacs B, Kwok WW, Nepom GT, Schlienger K, Riley JL, Allman D, Finkel TH, June CH.

J Immunol. 2004 Jun 1;172(11):6675-83.

33.
34.
35.

Tracking synapse-associated TCRs.

Finkel TH.

Nat Immunol. 2004 Feb;5(2):117; author reply 117. No abstract available.

PMID:
14749776
36.

CXCR4 engagement is required for HIV-1-induced L-selectin shedding.

Wang J, Marschner S, Finkel TH.

Blood. 2004 Feb 15;103(4):1218-21. Epub 2003 Oct 23.

38.

T cell signaling and apoptosis in HIV disease.

Selliah N, Shackelford J, Wang JF, Traynor F, Yin J, Finkel TH.

Immunol Res. 2003;27(2-3):247-60. Review.

PMID:
12857972
39.

Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation.

Kovacs B, Maus MV, Riley JL, Derimanov GS, Koretzky GA, June CH, Finkel TH.

Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15006-11. Epub 2002 Nov 5.

40.

Ligation of human CD4 interferes with antigen-induced activation of primary T cells.

Marschner S, Hünig T, Cambier JC, Finkel TH.

Immunol Lett. 2002 Jun 3;82(1-2):131-9.

PMID:
12008044
41.

Joseph Lee Hollander, MD, 1910--2000.

Eisenberg R, Schumacher HR, Finkel TH, Ehrlich GE.

Arthritis Rheum. 2000 Jul;43(7):1430. No abstract available.

42.

Central nervous system Sjögren's syndrome in a child: case report and review of the literature.

Gottfried JA, Finkel TH, Hunter JV, Carpentieri DF, Finkel RS.

J Child Neurol. 2001 Sep;16(9):683-5.

PMID:
11575610
43.

Juvenile arthritis and autoimmunity to type II collagen.

Myers LK, Higgins GC, Finkel TH, Reed AM, Thompson JW, Walton RC, Hendrickson J, Kerr NC, Pandya-Lipman RK, Shlopov BV, Stastny P, Postlethwaite AE, Kang AH.

Arthritis Rheum. 2001 Aug;44(8):1775-81.

44.

HIV-1 NL4-3, but not IIIB, inhibits JAK3/STAT5 activation in CD4(+) T cells.

Selliah N, Finkel TH.

Virology. 2001 Aug 1;286(2):412-21.

45.

Biochemical mechanisms of HIV induced T cell apoptosis.

Selliah N, Finkel TH.

Cell Death Differ. 2001 Feb;8(2):127-36. Review. No abstract available.

PMID:
11313714
46.

Nabumetone induced pseudoporphyria in childhood.

Cron RQ, Finkel TH.

J Rheumatol. 2000 Jul;27(7):1817-8. No abstract available.

PMID:
10914877
47.

Potential use of a caspase against HIV.

Finkel TH.

JAMA. 1999 Sep 15;282(11):1021-2. No abstract available.

PMID:
10493188
48.
49.

Ligation of the CD4 receptor induces activation-independent down-regulation of L-selectin.

Marschner S, Freiberg BA, Kupfer A, Hünig T, Finkel TH.

Proc Natl Acad Sci U S A. 1999 Aug 17;96(17):9763-8.

50.

Drug-induced lupus in a child after treatment with zafirlukast (Accolate).

Finkel TH, Hunter DJ, Paisley JE, Finkel RS, Larsen GL.

J Allergy Clin Immunol. 1999 Mar;103(3 Pt 1):533-4. No abstract available.

PMID:
10069891

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