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ZN148 - a modular synthetic metallo-β-lactamase inhibitor reverses carbapenem-resistance in Gram-negative pathogens in vivo.

Samuelsen Ø, Åstrand OAH, Fröhlich C, Heikal A, Skagseth S, Carlsen TJO, Leiros HS, Bayer A, Schnaars C, Kildahl-Andersen G, Lauksund S, Finke S, Huber S, Gjøen T, Andresen AMS, Økstad OA, Rongved P.

Antimicrob Agents Chemother. 2020 Mar 16. pii: AAC.02415-19. doi: 10.1128/AAC.02415-19. [Epub ahead of print]


Responsiveness of various reservoir species to oral rabies vaccination correlates with differences in vaccine uptake of mucosa associated lymphoid tissues.

Te Kamp V, Freuling CM, Vos A, Schuster P, Kaiser C, Ortmann S, Kretzschmar A, Nemitz S, Eggerbauer E, Ulrich R, Schinköthe J, Nolden T, Müller T, Finke S.

Sci Rep. 2020 Feb 19;10(1):2919. doi: 10.1038/s41598-020-59719-4.


Astrocyte Infection during Rabies Encephalitis Depends on the Virus Strain and Infection Route as Demonstrated by Novel Quantitative 3D Analysis of Cell Tropism.

Potratz M, Zaeck L, Christen M, Te Kamp V, Klein A, Nolden T, Freuling CM, Müller T, Finke S.

Cells. 2020 Feb 11;9(2). pii: E412. doi: 10.3390/cells9020412.


Further Evidence of Inadequate Quality in Lateral Flow Devices Commercially Offered for the Diagnosis of Rabies.

Klein A, Fahrion A, Finke S, Eyngor M, Novak S, Yakobson B, Ngoepe E, Phahladira B, Sabeta C, De Benedictis P, Gourlaouen M, Orciari LA, Yager PA, Gigante CM, Knowles MK, Fehlner-Gardiner C, Servat A, Cliquet F, Marston D, McElhinney LM, Johnson T, Fooks AR, Müller T, Freuling CM.

Trop Med Infect Dis. 2020 Jan 18;5(1). pii: E13. doi: 10.3390/tropicalmed5010013.


Interaction of host cellular factor ANP32B with matrix proteins of different paramyxoviruses.

Günther M, Bauer A, Müller M, Zaeck L, Finke S.

J Gen Virol. 2020 Jan;101(1):44-58. doi: 10.1099/jgv.0.001362.


Long-Term Immunogenicity and Efficacy of the Oral Rabies Virus Vaccine Strain SPBN GASGAS in Foxes.

Freuling CM, Kamp VT, Klein A, Günther M, Zaeck L, Potratz M, Eggerbauer E, Bobe K, Kaiser C, Kretzschmar A, Ortmann S, Schuster P, Vos A, Finke S, Müller T.

Viruses. 2019 Aug 27;11(9). pii: E790. doi: 10.3390/v11090790.


High-Resolution 3D Imaging of Rabies Virus Infection in Solvent-Cleared Brain Tissue.

Zaeck L, Potratz M, Freuling CM, Müller T, Finke S.

J Vis Exp. 2019 Apr 30;(146). doi: 10.3791/59402.


Bacillus cereus biofilm formation on central venous catheters of hospitalised cardiac patients.

Ikram S, Heikal A, Finke S, Hofgaard A, Rehman Y, Sabri AN, Økstad OA.

Biofouling. 2019 Feb;35(2):204-216. doi: 10.1080/08927014.2019.1586889. Epub 2019 Apr 5.


Esophageal Heat Exchanger Versus Water-Circulating Cooling Blanket for Targeted Temperature Management.

Schroeder DC, Maul AC, Guschlbauer M, Finke SR, de la Puente Bethencourt D, Neumann T, Padosch SA, Annecke T, Böttiger BW, Sterner-Kock A, Herff H.

Ther Hypothermia Temp Manag. 2019 Dec;9(4):251-257. doi: 10.1089/ther.2018.0054. Epub 2019 Mar 20.


Intravascular Cooling Device Versus Esophageal Heat Exchanger for Mild Therapeutic Hypothermia in an Experimental Setting.

Schroeder DC, Maul AC, Guschlbauer M, Finke SR, de la Puente Bethencourt D, Becker I, Padosch SA, Hohn A, Annecke T, Böttiger BW, Sterner-Kock A, Herff H.

Anesth Analg. 2019 Nov;129(5):1224-1231. doi: 10.1213/ANE.0000000000003922.


Experimental screening studies on rabies virus transmission and oral rabies vaccination of the Greater Kudu (Tragelaphus strepsiceros).

Hassel R, Vos A, Clausen P, Moore S, van der Westhuizen J, Khaiseb S, Kabajani J, Pfaff F, Höper D, Hundt B, Jago M, Bruwer F, Lindeque P, Finke S, Freuling CM, Müller T.

Sci Rep. 2018 Nov 9;8(1):16599. doi: 10.1038/s41598-018-34985-5.


A genome-wide siRNA screen identifies a druggable host pathway essential for the Ebola virus life cycle.

Martin S, Chiramel AI, Schmidt ML, Chen YC, Whitt N, Watt A, Dunham EC, Shifflett K, Traeger S, Leske A, Buehler E, Martellaro C, Brandt J, Wendt L, Müller A, Peitsch S, Best SM, Stech J, Finke S, Römer-Oberdörfer A, Groseth A, Feldmann H, Hoenen T.

Genome Med. 2018 Aug 7;10(1):58. doi: 10.1186/s13073-018-0570-1.


Isolation, antigenicity and immunogenicity of Lleida bat lyssavirus.

Banyard AC, Selden D, Wu G, Thorne L, Jennings D, Marston D, Finke S, Freuling CM, Müller T, Echevarría JE, Fooks AR.

J Gen Virol. 2018 Dec;99(12):1590-1599. doi: 10.1099/jgv.0.001068. Epub 2018 May 5.


Gender aspects in cardiopulmonary resuscitation by schoolchildren: A systematic review.

Finke SR, Schroeder DC, Ecker H, Wingen S, Hinkelbein J, Wetsch WA, Köhler D, Böttiger BW.

Resuscitation. 2018 Apr;125:70-78. doi: 10.1016/j.resuscitation.2018.01.025. Epub 2018 Feb 3. Review.



Fooks AR, Cliquet F, Finke S, Freuling C, Hemachudha T, Mani RS, Müller T, Nadin-Davis S, Picard-Meyer E, Wilde H, Banyard AC.

Nat Rev Dis Primers. 2017 Nov 30;3:17091. doi: 10.1038/nrdp.2017.91. Review.


The lyssavirus host-specificity conundrum-rabies virus-the exception not the rule.

Marston DA, Banyard AC, McElhinney LM, Freuling CM, Finke S, de Lamballerie X, Müller T, Fooks AR.

Curr Opin Virol. 2018 Feb;28:68-73. doi: 10.1016/j.coviro.2017.11.007. Epub 2017 Nov 25. Review.


Comparative pathogenesis of rabies in bats and carnivores, and implications for spillover to humans.

Begeman L, GeurtsvanKessel C, Finke S, Freuling CM, Koopmans M, Müller T, Ruigrok TJH, Kuiken T.

Lancet Infect Dis. 2018 Apr;18(4):e147-e159. doi: 10.1016/S1473-3099(17)30574-1. Epub 2017 Oct 31. Review. Erratum in: Lancet Infect Dis. 2017 Nov 29;:.


Efficacy of the oral rabies virus vaccine strain SPBN GASGAS in foxes and raccoon dogs.

Freuling CM, Eggerbauer E, Finke S, Kaiser C, Kaiser C, Kretzschmar A, Nolden T, Ortmann S, Schröder C, Teifke JP, Schuster P, Vos A, Mettenleiter TC, Müller T.

Vaccine. 2019 Aug 2;37(33):4750-4757. doi: 10.1016/j.vaccine.2017.09.093. Epub 2017 Oct 16.


Oral vaccination of wildlife against rabies: Differences among host species in vaccine uptake efficiency.

Vos A, Freuling CM, Hundt B, Kaiser C, Nemitz S, Neubert A, Nolden T, Teifke JP, Te Kamp V, Ulrich R, Finke S, Müller T.

Vaccine. 2017 Jul 13;35(32):3938-3944. doi: 10.1016/j.vaccine.2017.06.022. Epub 2017 Jun 19.


Comparative analysis of European bat lyssavirus 1 pathogenicity in the mouse model.

Eggerbauer E, Pfaff F, Finke S, Höper D, Beer M, Mettenleiter TC, Nolden T, Teifke JP, Müller T, Freuling CM.

PLoS Negl Trop Dis. 2017 Jun 19;11(6):e0005668. doi: 10.1371/journal.pntd.0005668. eCollection 2017 Jun.


Rapid Reverse Genetics Systems for Rhabdoviruses: From Forward to Reverse and Back Again.

Nolden T, Finke S.

Methods Mol Biol. 2017;1602:171-184. doi: 10.1007/978-1-4939-6964-7_12.


The putative drug efflux systems of the Bacillus cereus group.

Hassan KA, Fagerlund A, Elbourne LDH, Vörös A, Kroeger JK, Simm R, Tourasse NJ, Finke S, Henderson PJF, Økstad OA, Paulsen IT, Kolstø AB.

PLoS One. 2017 May 4;12(5):e0176188. doi: 10.1371/journal.pone.0176188. eCollection 2017.


Reverse genetics in high throughput: rapid generation of complete negative strand RNA virus cDNA clones and recombinant viruses thereof.

Nolden T, Pfaff F, Nemitz S, Freuling CM, Höper D, Müller T, Finke S.

Sci Rep. 2016 Apr 5;6:23887. doi: 10.1038/srep23887.


Expression, characterisation and antigenicity of a truncated Hendra virus attachment protein expressed in the protozoan host Leishmania tarentolae.

Fischer K, dos Reis VP, Finke S, Sauerhering L, Stroh E, Karger A, Maisner A, Groschup MH, Diederich S, Balkema-Buschmann A.

J Virol Methods. 2016 Feb;228:48-54. doi: 10.1016/j.jviromet.2015.11.006. Epub 2015 Nov 29.


Cationic amphiphilic drugs enhance entry of lentiviral particles pseudotyped with rabies virus glycoprotein into non-neuronal cells.

Klintworth A, Nolden T, Westhaus S, Rohrmann K, David S, Manns MP, Finke S, Ciesek S, von Hahn T.

Antiviral Res. 2015 Dec;124:122-31. doi: 10.1016/j.antiviral.2015.10.017. Epub 2015 Nov 2.


Receptor-mediated increase in rabies virus axonal transport.

Gluska S, Finke S, Perlson E.

Neural Regen Res. 2015 Jun;10(6):883-4. doi: 10.4103/1673-5374.158337. No abstract available.


A Dynein Light Chain 1 Binding Motif in Rabies Virus Polymerase L Protein Plays a Role in Microtubule Reorganization and Viral Primary Transcription.

Bauer A, Nolden T, Nemitz S, Perlson E, Finke S.

J Virol. 2015 Sep;89(18):9591-600. doi: 10.1128/JVI.01298-15. Epub 2015 Jul 8.


Anterograde glycoprotein-dependent transport of newly generated rabies virus in dorsal root ganglion neurons.

Bauer A, Nolden T, Schröter J, Römer-Oberdörfer A, Gluska S, Perlson E, Finke S.

J Virol. 2014 Dec;88(24):14172-83. doi: 10.1128/JVI.02254-14. Epub 2014 Oct 1.


Rabies Virus Hijacks and accelerates the p75NTR retrograde axonal transport machinery.

Gluska S, Zahavi EE, Chein M, Gradus T, Bauer A, Finke S, Perlson E.

PLoS Pathog. 2014 Aug 28;10(8):e1004348. doi: 10.1371/journal.ppat.1004348. eCollection 2014 Aug.


Comparative studies on the genetic, antigenic and pathogenic characteristics of Bokeloh bat lyssavirus.

Nolden T, Banyard AC, Finke S, Fooks AR, Hanke D, Höper D, Horton DL, Mettenleiter TC, Müller T, Teifke JP, Freuling CM.

J Gen Virol. 2014 Aug;95(Pt 8):1647-1653. doi: 10.1099/vir.0.065953-0. Epub 2014 May 14.


ANP32B is a nuclear target of henipavirus M proteins.

Bauer A, Neumann S, Karger A, Henning AK, Maisner A, Lamp B, Dietzel E, Kwasnitschka L, Balkema-Buschmann A, Keil GM, Finke S.

PLoS One. 2014 May 13;9(5):e97233. doi: 10.1371/journal.pone.0097233. eCollection 2014.


Urine protein profiling identified alpha-1-microglobulin and haptoglobin as biomarkers for early diagnosis of acute allograft rejection following kidney transplantation.

Stubendorff B, Finke S, Walter M, Kniemeyer O, von Eggeling F, Gruschwitz T, Steiner T, Ott U, Wolf G, Wunderlich H, Junker K.

World J Urol. 2014 Dec;32(6):1619-24. doi: 10.1007/s00345-014-1263-z. Epub 2014 Feb 19.


Integrins modulate the infection efficiency of West Nile virus into cells.

Schmidt K, Keller M, Bader BL, Korytář T, Finke S, Ziegler U, Groschup MH.

J Gen Virol. 2013 Aug;94(Pt 8):1723-1733. doi: 10.1099/vir.0.052613-0. Epub 2013 May 8.


Membrane and inclusion body targeting of lyssavirus matrix proteins.

Pollin R, Granzow H, Köllner B, Conzelmann KK, Finke S.

Cell Microbiol. 2013 Feb;15(2):200-12. doi: 10.1111/cmi.12037. Epub 2012 Oct 26.


Conventional and reciprocal approaches to the inverse dipole localization problem for N(20)-P (20) somatosensory evoked potentials.

Finke S, Gulrajani RM, Gotman J, Savard P.

Brain Topogr. 2013 Jan;26(1):24-34. doi: 10.1007/s10548-012-0238-x. Epub 2012 Jun 22.


What can we learn about lyssavirus genomes using 454 sequencing?

Höper D, Finke S, Freuling CM, Hoffmann B, Beer M.

Berl Munch Tierarztl Wochenschr. 2012 May-Jun;125(5-6):242-8.


Chimeric rabies viruses for trans-species comparison of lyssavirus glycoprotein ectodomain functions in virus replication and pathogenesis.

Genz B, Nolden T, Negatsch A, Teifke JP, Conzelmann KK, Finke S.

Berl Munch Tierarztl Wochenschr. 2012 May-Jun;125(5-6):219-27.


Interferon in lyssavirus infection.

Rieder M, Finke S, Conzelmann KK.

Berl Munch Tierarztl Wochenschr. 2012 May-Jun;125(5-6):209-18.


Assessment of inactivated human rabies vaccines: biochemical characterization and genetic identification of virus strains.

Finke S, Karger A, Freuling C, Müller T.

Vaccine. 2012 May 21;30(24):3603-9. doi: 10.1016/j.vaccine.2012.03.047. Epub 2012 Mar 31.


Immunogenicity studies in carnivores using a rabies virus construct with a site-directed deletion in the phosphoprotein.

Vos A, Conzelmann KK, Finke S, Müller T, Teifke J, Fooks AR, Neubert A.

Adv Prev Med. 2011;2011:898171. doi: 10.4061/2011/898171. Epub 2011 Sep 21.


Novel lyssavirus in Natterer's bat, Germany.

Freuling CM, Beer M, Conraths FJ, Finke S, Hoffmann B, Keller B, Kliemt J, Mettenleiter TC, Mühlbach E, Teifke JP, Wohlsein P, Müller T.

Emerg Infect Dis. 2011 Aug;17(8):1519-22. doi: 10.3201/eid1708.110201.


Generation of recombinant European bat lyssavirus type 1 and inter-genotypic compatibility of lyssavirus genotype 1 and 5 antigenome promoters.

Orbanz J, Finke S.

Arch Virol. 2010 Oct;155(10):1631-41. doi: 10.1007/s00705-010-0743-8. Epub 2010 Jul 8.


Intergenotypic replacement of lyssavirus matrix proteins demonstrates the role of lyssavirus M proteins in intracellular virus accumulation.

Finke S, Granzow H, Hurst J, Pollin R, Mettenleiter TC.

J Virol. 2010 Feb;84(4):1816-27. doi: 10.1128/JVI.01665-09. Epub 2009 Dec 2.


Attenuation of rabies virus replication and virulence by picornavirus internal ribosome entry site elements.

Marschalek A, Finke S, Schwemmle M, Mayer D, Heimrich B, Stitz L, Conzelmann KK.

J Virol. 2009 Feb;83(4):1911-9. doi: 10.1128/JVI.02055-08. Epub 2008 Dec 10.


Double-labeled rabies virus: live tracking of enveloped virus transport.

Klingen Y, Conzelmann KK, Finke S.

J Virol. 2008 Jan;82(1):237-45. Epub 2007 Oct 10.


Vesicle formation from the nuclear membrane is induced by coexpression of two conserved herpesvirus proteins.

Klupp BG, Granzow H, Fuchs W, Keil GM, Finke S, Mettenleiter TC.

Proc Natl Acad Sci U S A. 2007 Apr 24;104(17):7241-6. Epub 2007 Apr 10.


Monosynaptic restriction of transsynaptic tracing from single, genetically targeted neurons.

Wickersham IR, Lyon DC, Barnard RJ, Mori T, Finke S, Conzelmann KK, Young JA, Callaway EM.

Neuron. 2007 Mar 1;53(5):639-47.


Retrograde neuronal tracing with a deletion-mutant rabies virus.

Wickersham IR, Finke S, Conzelmann KK, Callaway EM.

Nat Methods. 2007 Jan;4(1):47-9. Epub 2006 Dec 10.


Green fluorescent protein-tagged adeno-associated virus particles allow the study of cytosolic and nuclear trafficking.

Lux K, Goerlitz N, Schlemminger S, Perabo L, Goldnau D, Endell J, Leike K, Kofler DM, Finke S, Hallek M, Büning H.

J Virol. 2005 Sep;79(18):11776-87.

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