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Items: 25


A nonrandomized trial of vitamin D supplementation for Barrett's esophagus.

Cummings LC, Thota PN, Willis JE, Chen Y, Cooper GS, Furey N, Bednarchik B, Alashkar BM, Dumot J, Faulx AL, Fink SP, Kresak AM, Abusneineh B, Barnholtz-Sloan J, Leahy P, Veigl ML, Chak A, Markowitz SD.

PLoS One. 2017 Sep 18;12(9):e0184928. doi: 10.1371/journal.pone.0184928. eCollection 2017.


Molecular Imaging of Colorectal Tumors by Targeting Colon Cancer Secreted Protein-2 (CCSP-2).

Kim J, Do EJ, Moinova H, Bae SM, Kang JY, Hong SM, Fink SP, Joo J, Suh YA, Jang SJ, Hwang SW, Park SH, Yang DH, Ye BD, Byeon JS, Choe J, Yang SK, Markowitz SD, Kim SY, Myung SJ.

Neoplasia. 2017 Oct;19(10):805-816. doi: 10.1016/j.neo.2017.07.003. Epub 2017 Sep 5.


Induction of KIAA1199/CEMIP is associated with colon cancer phenotype and poor patient survival.

Fink SP, Myeroff LL, Kariv R, Platzer P, Xin B, Mikkola D, Lawrence E, Morris N, Nosrati A, Willson JK, Willis J, Veigl M, Barnholtz-Sloan JS, Wang Z, Markowitz SD.

Oncotarget. 2015 Oct 13;6(31):30500-15. doi: 10.18632/oncotarget.5921.


TISSUE REGENERATION. Inhibition of the prostaglandin-degrading enzyme 15-PGDH potentiates tissue regeneration.

Zhang Y, Desai A, Yang SY, Bae KB, Antczak MI, Fink SP, Tiwari S, Willis JE, Williams NS, Dawson DM, Wald D, Chen WD, Wang Z, Kasturi L, Larusch GA, He L, Cominelli F, Di Martino L, Djuric Z, Milne GL, Chance M, Sanabria J, Dealwis C, Mikkola D, Naidoo J, Wei S, Tai HH, Gerson SL, Ready JM, Posner B, Willson JK, Markowitz SD.

Science. 2015 Jun 12;348(6240):aaa2340. doi: 10.1126/science.aaa2340.


Sulindac reversal of 15-PGDH-mediated resistance to colon tumor chemoprevention with NSAIDs.

Fink SP, Dawson DM, Zhang Y, Kresak A, Lawrence EG, Yang P, Chen Y, Barnholtz-Sloan JS, Willis JE, Kopelovich L, Markowitz SD.

Carcinogenesis. 2015 Feb;36(2):291-8. doi: 10.1093/carcin/bgu241. Epub 2014 Dec 10.


Inactivating mutation in the prostaglandin transporter gene, SLCO2A1, associated with familial digital clubbing, colon neoplasia, and NSAID resistance.

Guda K, Fink SP, Milne GL, Molyneaux N, Ravi L, Lewis SM, Dannenberg AJ, Montgomery CG, Zhang S, Willis J, Wiesner GL, Markowitz SD.

Cancer Prev Res (Phila). 2014 Aug;7(8):805-12. doi: 10.1158/1940-6207.CAPR-14-0108. Epub 2014 May 16.


Aspirin and the risk of colorectal cancer in relation to the expression of 15-hydroxyprostaglandin dehydrogenase (HPGD).

Fink SP, Yamauchi M, Nishihara R, Jung S, Kuchiba A, Wu K, Cho E, Giovannucci E, Fuchs CS, Ogino S, Markowitz SD, Chan AT.

Sci Transl Med. 2014 Apr 23;6(233):233re2. doi: 10.1126/scitranslmed.3008481.


Genetic variation in 15-hydroxyprostaglandin dehydrogenase and colon cancer susceptibility.

Thompson CL, Fink SP, Lutterbaugh JD, Elston RC, Veigl ML, Markowitz SD, Li L.

PLoS One. 2013 May 22;8(5):e64122. doi: 10.1371/journal.pone.0064122. Print 2013.


Colonic 15-PGDH levels are stable across distance and time and are not perturbed by aspirin intervention.

Fink SP, Yang DH, Barnholtz-Sloan JS, Ryu YM, Mikkola D, Potter JD, Lampe JW, Markowitz SD, Myung SJ.

Dig Dis Sci. 2013 Sep;58(9):2615-22. doi: 10.1007/s10620-013-2670-5. Epub 2013 Apr 27.


Inhibition of 15-hydroxyprostaglandin dehydrogenase by Helicobacter pylori in human gastric carcinogenesis.

Ryu YM, Myung SJ, Park YS, Yang DH, Song HJ, Jeong JY, Lee SM, Song M, Kim DH, Lee HJ, Park SK, Fink SP, Markowitz SD, Jung KW, Kim KJ, Ye BD, Byeon JS, Jung HY, Yang SK, Kim JH.

Cancer Prev Res (Phila). 2013 Apr;6(4):349-59. doi: 10.1158/1940-6207.CAPR-12-0389. Epub 2013 Feb 19.


15-hydroxyprostaglandin dehydrogenase is downregulated and exhibits tumor suppressor activity in gastric cancer.

Song HJ, Myung SJ, Kim IW, Jeong JY, Park YS, Lee SM, Nam WH, Ryu YM, Fink SP, Yang DH, Jung HY, Kim JH.

Cancer Invest. 2011 May;29(4):257-65. doi: 10.3109/07357907.2011.568562.


15-Hydroxyprostaglandin dehydrogenase inactivation as a mechanism of resistance to celecoxib chemoprevention of colon tumors.

Yan M, Myung SJ, Fink SP, Lawrence E, Lutterbaugh J, Yang P, Zhou X, Liu D, Rerko RM, Willis J, Dawson D, Tai HH, Barnholtz-Sloan JS, Newman RA, Bertagnolli MM, Markowitz SD.

Proc Natl Acad Sci U S A. 2009 Jun 9;106(23):9409-13. doi: 10.1073/pnas.0902367106. Epub 2009 May 22.


Ugene, a newly identified protein that is commonly overexpressed in cancer and binds uracil DNA glycosylase.

Guo C, Zhang X, Fink SP, Platzer P, Wilson K, Willson JK, Wang Z, Markowitz SD.

Cancer Res. 2008 Aug 1;68(15):6118-26. doi: 10.1158/0008-5472.CAN-08-1259.


Colon cancer secreted protein-2 (CCSP-2), a novel candidate serological marker of colon neoplasia.

Xin B, Platzer P, Fink SP, Reese L, Nosrati A, Willson JK, Wilson K, Markowitz S.

Oncogene. 2005 Jan 20;24(4):724-31.


TGF-beta-induced nuclear localization of Smad2 and Smad3 in Smad4 null cancer cell lines.

Fink SP, Mikkola D, Willson JK, Markowitz S.

Oncogene. 2003 Mar 6;22(9):1317-23.


Transforming growth factor-beta-induced growth inhibition in a Smad4 mutant colon adenoma cell line.

Fink SP, Swinler SE, Lutterbaugh JD, Massagué J, Thiagalingam S, Kinzler KW, Vogelstein B, Willson JK, Markowitz S.

Cancer Res. 2001 Jan 1;61(1):256-60.


Mutation detection in the TGF-beta receptors and smad genes: RT-PCR and sequencing.

Myeroff LL, He H, Fink SP, Markowitz S.

Methods Mol Biol. 2000;142:139-47. Review. No abstract available.


MutS recognition of exocyclic DNA adducts that are endogenous products of lipid oxidation.

Johnson KA, Mierzwa ML, Fink SP, Marnett LJ.

J Biol Chem. 1999 Sep 17;274(38):27112-8.


Mutagenicity in Escherichia coli of the major DNA adduct derived from the endogenous mutagen malondialdehyde.

Fink SP, Reddy GR, Marnett LJ.

Proc Natl Acad Sci U S A. 1997 Aug 5;94(16):8652-7.


Repair of propanodeoxyguanosine by nucleotide excision repair in vivo and in vitro.

Johnson KA, Fink SP, Marnett LJ.

J Biol Chem. 1997 Apr 25;272(17):11434-8.


Refractory ceramic fibers activate alveolar macrophage eicosanoid and cytokine release.

Leikauf GD, Fink SP, Miller ML, Lockey JE, Driscoll KE.

J Appl Physiol (1985). 1995 Jan;78(1):164-71.


Taxol-induced flexibility of microtubules and its reversal by MAP-2 and Tau.

Dye RB, Fink SP, Williams RC Jr.

J Biol Chem. 1993 Apr 5;268(10):6847-50.

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