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Cutting Edge: Glycolytic Metabolism and Mitochondrial Metabolism Are Uncoupled in Antigen-Activated CD8+ Recent Thymic Emigrants.

Cunningham CA, Hoppins S, Fink PJ.

J Immunol. 2018 Sep 15;201(6):1627-1632. doi: 10.4049/jimmunol.1800705. Epub 2018 Aug 1.


The Cancer Immunotherapy Revolution: Mechanistic Insights.

Fink PJ.

J Immunol. 2018 Jan 15;200(2):371-372. doi: 10.4049/jimmunol.1790024. No abstract available.


Reinterpreting recent thymic emigrant function: defective or adaptive?

Cunningham CA, Helm EY, Fink PJ.

Curr Opin Immunol. 2018 Apr;51:1-6. doi: 10.1016/j.coi.2017.12.006. Epub 2017 Dec 16. Review.


Cutting Edge: Defective Aerobic Glycolysis Defines the Distinct Effector Function in Antigen-Activated CD8+ Recent Thymic Emigrants.

Cunningham CA, Bergsbaken T, Fink PJ.

J Immunol. 2017 Jun 15;198(12):4575-4580. doi: 10.4049/jimmunol.1700465. Epub 2017 May 15.


Local Inflammatory Cues Regulate Differentiation and Persistence of CD8+ Tissue-Resident Memory T Cells.

Bergsbaken T, Bevan MJ, Fink PJ.

Cell Rep. 2017 Apr 4;19(1):114-124. doi: 10.1016/j.celrep.2017.03.031.


Analysis of Shigella flexneri Resistance, Biofilm Formation, and Transcriptional Profile in Response to Bile Salts.

Nickerson KP, Chanin RB, Sistrunk JR, Rasko DA, Fink PJ, Barry EM, Nataro JP, Faherty CS.

Infect Immun. 2017 May 23;85(6). pii: e01067-16. doi: 10.1128/IAI.01067-16. Print 2017 Jun.


The Macro Influence of the Microbiome.

Fink PJ.

J Immunol. 2017 Jan 15;198(2):553. doi: 10.4049/jimmunol.1690022. No abstract available.


Recent thymic emigrants are tolerized in the absence of inflammation.

Friesen TJ, Ji Q, Fink PJ.

J Exp Med. 2016 May 30;213(6):913-20. doi: 10.1084/jem.20151990. Epub 2016 May 2.


Cutting Edge: Enhanced Clonal Burst Size Corrects an Otherwise Defective Memory Response by CD8+ Recent Thymic Emigrants.

Deets KA, Berkley AM, Bergsbaken T, Fink PJ.

J Immunol. 2016 Mar 15;196(6):2450-5. doi: 10.4049/jimmunol.1502525. Epub 2016 Feb 12.


A Century of Excellence: Celebrating 100 Years of The Journal of Immunology.

Fink PJ, Hogan MM, Kenyon KJ.

J Immunol. 2016 Feb 1;196(3):935-6. doi: 10.4049/jimmunol.1590029. No abstract available.


Comments from the Editor-in-Chief.

Fink PJ.

J Immunol. 2016 Jan 15;196(2):521. doi: 10.4049/jimmunol.1502280. No abstract available.


ICOS and Bcl6-dependent pathways maintain a CD4 T cell population with memory-like properties during tuberculosis.

Moguche AO, Shafiani S, Clemons C, Larson RP, Dinh C, Higdon LE, Cambier CJ, Sissons JR, Gallegos AM, Fink PJ, Urdahl KB.

J Exp Med. 2015 May 4;212(5):715-28. doi: 10.1084/jem.20141518. Epub 2015 Apr 27.


Heme exporter FLVCR is required for T cell development and peripheral survival.

Philip M, Funkhouser SA, Chiu EY, Phelps SR, Delrow JJ, Cox J, Fink PJ, Abkowitz JL.

J Immunol. 2015 Feb 15;194(4):1677-85. doi: 10.4049/jimmunol.1402172. Epub 2015 Jan 12.


Receptor revision in CD4 T cells is influenced by follicular helper T cell formation and germinal-center interactions.

Higdon LE, Deets KA, Friesen TJ, Sze KY, Fink PJ.

Proc Natl Acad Sci U S A. 2014 Apr 15;111(15):5652-7. doi: 10.1073/pnas.1321803111. Epub 2014 Mar 31.


The ribosomal protein Rpl22 controls ribosome composition by directly repressing expression of its own paralog, Rpl22l1.

O'Leary MN, Schreiber KH, Zhang Y, Duc AC, Rao S, Hale JS, Academia EC, Shah SR, Morton JF, Holstein CA, Martin DB, Kaeberlein M, Ladiges WC, Fink PJ, Mackay VL, Wiest DL, Kennedy BK.

PLoS Genet. 2013;9(8):e1003708. doi: 10.1371/journal.pgen.1003708. Epub 2013 Aug 22.


Working to fill the boss's shoes.

Fink PJ.

J Immunol. 2013 Jul 1;191(1):1-2. doi: 10.4049/jimmunol.1390035. No abstract available.


Immune vulnerability of infants to tuberculosis.

Vanden Driessche K, Persson A, Marais BJ, Fink PJ, Urdahl KB.

Clin Dev Immunol. 2013;2013:781320. doi: 10.1155/2013/781320. Epub 2013 May 13. Review.


Recent thymic emigrants and mature naive T cells exhibit differential DNA methylation at key cytokine loci.

Berkley AM, Hendricks DW, Simmons KB, Fink PJ.

J Immunol. 2013 Jun 15;190(12):6180-6. doi: 10.4049/jimmunol.1300181. Epub 2013 May 17.


The biology of recent thymic emigrants.

Fink PJ.

Annu Rev Immunol. 2013;31:31-50. doi: 10.1146/annurev-immunol-032712-100010. Epub 2012 Nov 1. Review.


Thymus-autonomous T cell development in the absence of progenitor import.

Martins VC, Ruggiero E, Schlenner SM, Madan V, Schmidt M, Fink PJ, von Kalle C, Rodewald HR.

J Exp Med. 2012 Jul 30;209(8):1409-17. doi: 10.1084/jem.20120846. Epub 2012 Jul 9.


Homeostatic signals do not drive post-thymic T cell maturation.

Houston EG Jr, Boursalian TE, Fink PJ.

Cell Immunol. 2012;274(1-2):39-45. doi: 10.1016/j.cellimm.2012.02.005. Epub 2012 Feb 17.


Modulation of TCR╬▓ surface expression during TCR revision.

Simmons KB, Wubeshet M, Ames KT, McMahan CJ, Hale JS, Fink PJ.

Cell Immunol. 2012;272(2):124-9. doi: 10.1016/j.cellimm.2011.10.022. Epub 2011 Nov 15.


Post-thymic maturation: young T cells assert their individuality.

Fink PJ, Hendricks DW.

Nat Rev Immunol. 2011 Jul 22;11(8):544-9. doi: 10.1038/nri3028. Review.


Recent thymic emigrants are preferentially incorporated only into the depleted T-cell pool.

Houston EG Jr, Higdon LE, Fink PJ.

Proc Natl Acad Sci U S A. 2011 Mar 29;108(13):5366-71. doi: 10.1073/pnas.1015286108. Epub 2011 Mar 14.


Bcl-2-interacting mediator of cell death influences autoantigen-driven deletion and TCR revision.

Hale JS, Nelson LT, Simmons KB, Fink PJ.

J Immunol. 2011 Jan 15;186(2):799-806. doi: 10.4049/jimmunol.1002933. Epub 2010 Dec 10.


Recent thymic emigrants are biased against the T-helper type 1 and toward the T-helper type 2 effector lineage.

Hendricks DW, Fink PJ.

Blood. 2011 Jan 27;117(4):1239-49. doi: 10.1182/blood-2010-07-299263. Epub 2010 Nov 3.


TCR revision generates functional CD4+ T cells.

Hale JS, Wubeshet M, Fink PJ.

J Immunol. 2010 Dec 1;185(11):6528-34. doi: 10.4049/jimmunol.1002696. Epub 2010 Oct 22.


Cutting Edge: Rag deletion in peripheral T cells blocks TCR revision.

Hale JS, Ames KT, Boursalian TE, Fink PJ.

J Immunol. 2010 Jun 1;184(11):5964-8. doi: 10.4049/jimmunol.1000876. Epub 2010 Apr 30.


Cell-extrinsic defective lymphocyte development in Lmna(-/-) mice.

Hale JS, Frock RL, Mamman SA, Fink PJ, Kennedy BK.

PLoS One. 2010 Apr 12;5(4):e10127. doi: 10.1371/journal.pone.0010127.


T-cell receptor revision: friend or foe?

Hale JS, Fink PJ.

Immunology. 2010 Apr;129(4):467-73. doi: 10.1111/j.1365-2567.2010.03250.x. Epub 2010 Feb 26. Review.


Cutting edge: spontaneous development of IL-17-producing gamma delta T cells in the thymus occurs via a TGF-beta 1-dependent mechanism.

Do JS, Fink PJ, Li L, Spolski R, Robinson J, Leonard WJ, Letterio JJ, Min B.

J Immunol. 2010 Feb 15;184(4):1675-9. doi: 10.4049/jimmunol.0903539. Epub 2010 Jan 8.


MHC drives TCR repertoire shaping, but not maturation, in recent thymic emigrants.

Houston EG Jr, Fink PJ.

J Immunol. 2009 Dec 1;183(11):7244-9. doi: 10.4049/jimmunol.0902313. Epub 2009 Nov 13.


RTEs: lazy T-cell teenagers.

Fink PJ.

Blood. 2009 May 28;113(22):5374-5. doi: 10.1182/blood-2009-03-207308. No abstract available.


Uneven colonization of the lymphoid periphery by T cells that undergo early TCR{alpha} rearrangements.

Hendricks DW, Fink PJ.

J Immunol. 2009 Apr 1;182(7):4267-74. doi: 10.4049/jimmunol.0804180.


Postthymic maturation influences the CD8 T cell response to antigen.

Makaroff LE, Hendricks DW, Niec RE, Fink PJ.

Proc Natl Acad Sci U S A. 2009 Mar 24;106(12):4799-804. doi: 10.1073/pnas.0812354106. Epub 2009 Mar 6.


Back to the thymus: peripheral T cells come home.

Hale JS, Fink PJ.

Immunol Cell Biol. 2009 Jan;87(1):58-64. doi: 10.1038/icb.2008.87. Epub 2008 Nov 25. Review.


Cutting edge: Contact with secondary lymphoid organs drives postthymic T cell maturation.

Houston EG Jr, Nechanitzky R, Fink PJ.

J Immunol. 2008 Oct 15;181(8):5213-7.


Immunology: Surprising side effects.

Bevan MJ, Fink PJ.

Nature. 2008 Aug 14;454(7206):837-8. doi: 10.1038/454837a. No abstract available.


More than just vanilla.

Fink PJ.

J Immunol. 2008 Apr 1;180(7):4351-2. No abstract available.


Cutting edge: two distinct motifs within the Fas ligand tail regulate Fas ligand-mediated costimulation.

Sun M, Lee S, Karray S, Levi-Strauss M, Ames KT, Fink PJ.

J Immunol. 2007 Nov 1;179(9):5639-43.


A new class of reverse signaling costimulators belongs to the TNF family.

Sun M, Fink PJ.

J Immunol. 2007 Oct 1;179(7):4307-12. Review.


IntroductionExposing Misinformation Concerning Child Sexual Abuse and Adult Survivors.

Whitfield CL, Silberg J, Fink PJ.

J Child Sex Abus. 2000;9(3-4):1-8.


Elimination of antigen-presenting cells and autoreactive T cells by Fas contributes to prevention of autoimmunity.

Stranges PB, Watson J, Cooper CJ, Choisy-Rossi CM, Stonebraker AC, Beighton RA, Hartig H, Sundberg JP, Servick S, Kaufmann G, Fink PJ, Chervonsky AV.

Immunity. 2007 May;26(5):629-41.


The cytoplasmic domain of Fas ligand costimulates TCR signals.

Sun M, Ames KT, Suzuki I, Fink PJ.

J Immunol. 2006 Aug 1;177(3):1481-91.


T cells stop to smell the (antigenic) roses.

Fink PJ.

J Immunol. 2006 Aug 1;177(3):1379-80. No abstract available.


Thymic output in aged mice.

Hale JS, Boursalian TE, Turk GL, Fink PJ.

Proc Natl Acad Sci U S A. 2006 May 30;103(22):8447-52. Epub 2006 May 22.


T cells join the Blimp-1 brigade.

Fink PJ.

Nat Immunol. 2006 May;7(5):445-6. No abstract available.


An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia.

Hajjar AM, Harowicz H, Liggitt HD, Fink PJ, Wilson CB, Skerrett SJ.

Am J Respir Cell Mol Biol. 2005 Nov;33(5):470-5. Epub 2005 Aug 11.

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