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Items: 1 to 50 of 114

1.

IKKβ regulates endothelial thrombomodulin in a Klf2-dependent manner.

Pathak R, Shao L, Chafekar SM, Feng W, Ponnappan U, Fink LM, Zhou D, Hauer-Jensen M.

J Thromb Haemost. 2014 Sep;12(9):1533-1544. doi: 10.1111/jth.12664. Epub 2014 Aug 11.

2.

Circulating tumor cell counts are prognostic of overall survival in SWOG S0421: a phase III trial of docetaxel with or without atrasentan for metastatic castration-resistant prostate cancer.

Goldkorn A, Ely B, Quinn DI, Tangen CM, Fink LM, Xu T, Twardowski P, Van Veldhuizen PJ, Agarwal N, Carducci MA, Monk JP 3rd, Datar RH, Garzotto M, Mack PC, Lara P Jr, Higano CS, Hussain M, Thompson IM Jr, Cote RJ, Vogelzang NJ.

J Clin Oncol. 2014 Apr 10;32(11):1136-42. doi: 10.1200/JCO.2013.51.7417. Epub 2014 Mar 10.

3.

Pharmacological targeting of the thrombomodulin-activated protein C pathway mitigates radiation toxicity.

Geiger H, Pawar SA, Kerschen EJ, Nattamai KJ, Hernandez I, Liang HP, Fernández JÁ, Cancelas JA, Ryan MA, Kustikova O, Schambach A, Fu Q, Wang J, Fink LM, Petersen KU, Zhou D, Griffin JH, Baum C, Weiler H, Hauer-Jensen M.

Nat Med. 2012 Jul;18(7):1123-9. doi: 10.1038/nm.2813.

4.

Inhibition of protease-activated receptor 1 ameliorates intestinal radiation mucositis in a preclinical rat model.

Wang J, Kulkarni A, Chintala M, Fink LM, Hauer-Jensen M.

Int J Radiat Oncol Biol Phys. 2013 Jan 1;85(1):208-14. doi: 10.1016/j.ijrobp.2012.02.007. Epub 2012 May 12.

5.

Procalcitonin as a predictive biomarker for total body irradiation-induced bacterial load and lethality in mice.

Biju PG, Garg S, Wang W, Choudhry MA, Kovacs EJ, Fink LM, Hauer-Jensen M.

Shock. 2012 Aug;38(2):170-6. doi: 10.1097/SHK.0b013e31825b2db3.

6.

Isolation, characterization, and in vitro propagation of infantile hemangioma stem cells and an in vivo mouse model.

Xu D, O TM, Shartava A, Fowles TC, Yang J, Fink LM, Ward DC, Mihm MC, Waner M, Ma Y.

J Hematol Oncol. 2011 Dec 22;4:54. doi: 10.1186/1756-8722-4-54.

7.

Enhanced self-renewal of hematopoietic stem/progenitor cells mediated by the stem cell gene Sall4.

Yang J, Aguila JR, Alipio Z, Lai R, Fink LM, Ma Y.

J Hematol Oncol. 2011 Sep 23;4:38. doi: 10.1186/1756-8722-4-38.

8.

Comparison of circulating MicroRNA 141 to circulating tumor cells, lactate dehydrogenase, and prostate-specific antigen for determining treatment response in patients with metastatic prostate cancer.

Gonzales JC, Fink LM, Goodman OB Jr, Symanowski JT, Vogelzang NJ, Ward DC.

Clin Genitourin Cancer. 2011 Sep;9(1):39-45. doi: 10.1016/j.clgc.2011.05.008. Epub 2011 Jul 1.

PMID:
21723797
9.

Circulating tumor cells as a predictive biomarker in patients with hormone-sensitive prostate cancer.

Goodman OB Jr, Symanowski JT, Loudyi A, Fink LM, Ward DC, Vogelzang NJ.

Clin Genitourin Cancer. 2011 Sep;9(1):31-8. doi: 10.1016/j.clgc.2011.04.001. Epub 2011 Jun 25.

PMID:
21705286
10.

Epithelial to mesenchymal transition (EMT) induced by bleomycin or TFG(b1)/EGF in murine induced pluripotent stem cell-derived alveolar Type II-like cells.

Alipio ZA, Jones N, Liao W, Yang J, Kulkarni S, Sree Kumar K, Hauer-Jensen M, Ward DC, Ma Y, Fink LM.

Differentiation. 2011 Sep;82(2):89-98. doi: 10.1016/j.diff.2011.05.001. Epub 2011 May 18.

PMID:
21596473
11.

Non-small cell lung cancer cells expressing CD44 are enriched for stem cell-like properties.

Leung EL, Fiscus RR, Tung JW, Tin VP, Cheng LC, Sihoe AD, Fink LM, Ma Y, Wong MP.

PLoS One. 2010 Nov 19;5(11):e14062. doi: 10.1371/journal.pone.0014062.

12.

Increases in quantitative D-dimer levels correlate with progressive disease better than circulating tumor cell counts in patients with refractory prostate cancer.

Khoury JD, Adcock DM, Chan F, Symanowski JT, Tiefenbacher S, Goodman O, Paz L, Ma Y, Ward DC, Vogelzang NJ, Fink LM.

Am J Clin Pathol. 2010 Dec;134(6):964-9. doi: 10.1309/AJCPH92SXYLIKKTS.

PMID:
21088161
13.

Reversal of hyperglycemia in diabetic mouse models using induced-pluripotent stem (iPS)-derived pancreatic beta-like cells.

Alipio Z, Liao W, Roemer EJ, Waner M, Fink LM, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13426-31. doi: 10.1073/pnas.1007884107. Epub 2010 Jul 7.

14.

Sustained factor VIII production in hemophiliac mice 1 year after engraftment with induced pluripotent stem cell-derived factor VIII producing endothelial cells.

Alipio Z, Adcock DM, Waner M, O TM, Fink LM, Ward DC, Ma Y.

Blood Coagul Fibrinolysis. 2010 Jul;21(5):502-4. doi: 10.1097/MBC.0b013e32833580e9. No abstract available.

PMID:
20595826
15.

Generation of murine hepatic lineage cells from induced pluripotent stem cells.

Gai H, Nguyen DM, Moon YJ, Aguila JR, Fink LM, Ward DC, Ma Y.

Differentiation. 2010 Mar;79(3):171-81. doi: 10.1016/j.diff.2010.01.002. Epub 2010 Jan 27.

PMID:
20106584
16.

Generation and characterization of functional cardiomyocytes using induced pluripotent stem cells derived from human fibroblasts.

Gai H, Leung EL, Costantino PD, Aguila JR, Nguyen DM, Fink LM, Ward DC, Ma Y.

Cell Biol Int. 2009 Nov;33(11):1184-93. doi: 10.1016/j.cellbi.2009.08.008. Epub 2009 Sep 1.

PMID:
19729070
17.

Thrombotic events in patients with cancer receiving antiangiogenesis agents.

Zangari M, Fink LM, Elice F, Zhan F, Adcock DM, Tricot GJ.

J Clin Oncol. 2009 Oct 10;27(29):4865-73. doi: 10.1200/JCO.2009.22.3875. Epub 2009 Aug 24. Review.

PMID:
19704059
18.

Circulating tumor cells in patients with castration-resistant prostate cancer baseline values and correlation with prognostic factors.

Goodman OB Jr, Fink LM, Symanowski JT, Wong B, Grobaski B, Pomerantz D, Ma Y, Ward DC, Vogelzang NJ.

Cancer Epidemiol Biomarkers Prev. 2009 Jun;18(6):1904-13. doi: 10.1158/1055-9965.EPI-08-1173.

19.

Hypercoagulable states in patients with multiple myeloma can affect the thalidomide-associated venous thromboembolism.

Talamo GP, Ibrahim S, Claxton D, Tricot GJ, Fink LM, Zangari M.

Blood Coagul Fibrinolysis. 2009 Jul;20(5):337-9. doi: 10.1097/MBC.0b013e32832b27e6.

PMID:
19367157
20.

Phenotypic correction of murine hemophilia A using an iPS cell-based therapy.

Xu D, Alipio Z, Fink LM, Adcock DM, Yang J, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2009 Jan 20;106(3):808-13. doi: 10.1073/pnas.0812090106. Epub 2009 Jan 12.

21.

Genome-wide analysis reveals Sall4 to be a major regulator of pluripotency in murine-embryonic stem cells.

Yang J, Chai L, Fowles TC, Alipio Z, Xu D, Fink LM, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2008 Dec 16;105(50):19756-61. doi: 10.1073/pnas.0809321105. Epub 2008 Dec 5.

22.

Call for revision of College of American Pathologists-mandated requirements for retention of laboratory records and materials.

Khoury JD, Fink LM, Vogelzang NJ.

Arch Pathol Lab Med. 2008 Nov;132(11):1712-3; discussion 1713. doi: 10.1043/1543-2165-132.11.1712. No abstract available.

PMID:
18975998
23.

Comparative gene expression profiling in three primary human cell lines after treatment with a novel inhibitor of Rho kinase or atorvastatin.

Boerma M, Fu Q, Wang J, Loose DS, Bartolozzi A, Ellis JL, McGonigle S, Paradise E, Sweetnam P, Fink LM, Vozenin-Brotons MC, Hauer-Jensen M.

Blood Coagul Fibrinolysis. 2008 Oct;19(7):709-18. doi: 10.1097/MBC.0b013e32830b2891.

24.

The hemostatic system and malignancy.

Adcock DM, Fink LM, Marlar RA, Cavallo F, Zangari M.

Clin Lymphoma Myeloma. 2008 Aug;8(4):230-6. doi: 10.3816/CLM.2008.n.030. Review.

PMID:
18765310
25.

Involvement of heat shock factor 1 in statin-induced transcriptional upregulation of endothelial thrombomodulin.

Fu Q, Wang J, Boerma M, Berbée M, Qiu X, Fink LM, Hauer-Jensen M.

Circ Res. 2008 Aug 15;103(4):369-77. doi: 10.1161/CIRCRESAHA.108.174607. Epub 2008 Jul 3.

26.

SALL4 is a key regulator of survival and apoptosis in human leukemic cells.

Yang J, Chai L, Gao C, Fowles TC, Alipio Z, Dang H, Xu D, Fink LM, Ward DC, Ma Y.

Blood. 2008 Aug 1;112(3):805-13. doi: 10.1182/blood-2007-11-126326. Epub 2008 May 16. Erratum in: Blood. 2009 Oct 1; 114(14):3131.

27.

Inactivation of thrombomodulin by ionizing radiation in a cell-free system: possible implications for radiation responses in vascular endothelium.

Ross CC, MacLeod SL, Plaxco JR, Froude JW, Fink LM, Wang J, Stites WE, Hauer-Jensen M.

Radiat Res. 2008 Apr;169(4):408-16. doi: 10.1667/RR1148.1.

28.

Simvastatin ameliorates radiation enteropathy development after localized, fractionated irradiation by a protein C-independent mechanism.

Wang J, Boerma M, Fu Q, Kulkarni A, Fink LM, Hauer-Jensen M.

Int J Radiat Oncol Biol Phys. 2007 Aug 1;68(5):1483-90.

29.

Bmi-1 is a target gene for SALL4 in hematopoietic and leukemic cells.

Yang J, Chai L, Liu F, Fink LM, Lin P, Silberstein LE, Amin HM, Ward DC, Ma Y.

Proc Natl Acad Sci U S A. 2007 Jun 19;104(25):10494-9. Epub 2007 Jun 8.

30.

Comparison of mortality rates in statin users versus nonstatin users in a United States veteran population.

Mehta JL, Bursac Z, Hauer-Jensen M, Fort C, Fink LM.

Am J Cardiol. 2006 Oct 1;98(7):923-8. Epub 2006 Aug 7.

PMID:
16996875
31.

Comparative expression profiling in primary and immortalized endothelial cells: changes in gene expression in response to hydroxy methylglutaryl-coenzyme A reductase inhibition.

Boerma M, Burton GR, Wang J, Fink LM, McGehee RE Jr, Hauer-Jensen M.

Blood Coagul Fibrinolysis. 2006 Apr;17(3):173-80.

PMID:
16575254
32.

Modulation of the intestinal response to ionizing radiation by anticoagulant and non-anticoagulant heparins.

Wang J, Zheng H, Qiu X, Kulkarni A, Fink LM, Hauer-Jensen M.

Thromb Haemost. 2005 Nov;94(5):1054-9.

PMID:
16366003
33.

Influence of statins on postoperative wound complications after inguinal or ventral herniorrhaphy.

Hauer-Jensen M, Fort C, Mehta JL, Fink LM.

Hernia. 2006 Mar;10(1):48-52. Epub 2005 Sep 8.

PMID:
16151608
35.

Radiation injury and the protein C pathway.

Hauer-Jensen M, Fink LM, Wang J.

Crit Care Med. 2004 May;32(5 Suppl):S325-30. Review.

PMID:
15118539
36.

Infrared imaging of subcutaneous veins.

Zharov VP, Ferguson S, Eidt JF, Howard PC, Fink LM, Waner M.

Lasers Surg Med. 2004;34(1):56-61.

PMID:
14755425
37.

Recombinant factor VIIa in the treatment of bleeding.

Midathada MV, Mehta P, Waner M, Fink LM.

Am J Clin Pathol. 2004 Jan;121(1):124-37. Review.

PMID:
14750250
38.

Statins increase thrombomodulin expression and function in human endothelial cells by a nitric oxide-dependent mechanism and counteract tumor necrosis factor alpha-induced thrombomodulin downregulation.

Shi J, Wang J, Zheng H, Ling W, Joseph J, Li D, Mehta JL, Ponnappan U, Lin P, Fink LM, Hauer-Jensen M.

Blood Coagul Fibrinolysis. 2003 Sep;14(6):575-85.

PMID:
12960612
39.

Insulin sensitivity and plasma homocysteine concentrations in non-diabetic obese and normal weight subjects.

Fonseca VA, Fink LM, Kern PA.

Atherosclerosis. 2003 Mar;167(1):105-9.

PMID:
12618274
40.

Hyperhomocysteinemia leads to adverse cardiac remodeling in hypertensive rats.

Joseph J, Washington A, Joseph L, Koehler L, Fink LM, Hauer-Jensen M, Kennedy RH.

Am J Physiol Heart Circ Physiol. 2002 Dec;283(6):H2567-74. Epub 2002 Aug 29.

43.

Cytokines in coagulation and thrombosis: a preclinical and clinical review.

Joseph L, Fink LM, Hauer-Jensen M.

Blood Coagul Fibrinolysis. 2002 Mar;13(2):105-16. Review.

PMID:
11914652
44.

Short-term inhibition of ADP-induced platelet aggregation by clopidogrel ameliorates radiation-induced toxicity in rat small intestine.

Wang J, Albertson CM, Zheng H, Fink LM, Herbert JM, Hauer-Jensen M.

Thromb Haemost. 2002 Jan;87(1):122-8.

PMID:
11848440
45.

Association between decreased pulmonary endothelial cell thrombomodulin and local fibrin deposition in pneumonia.

Albertson CM, Richter KK, Kudryk BJ, Fink LM, Hauer-Jensen M.

Blood Coagul Fibrinolysis. 2001 Dec;12(8):729-33.

PMID:
11734675
46.
47.

Blood S-adenosylmethionine concentrations and lymphocyte methylenetetrahydrofolate reductase activity in diabetes mellitus and diabetic nephropathy.

Poirier LA, Brown AT, Fink LM, Wise CK, Randolph CJ, Delongchamp RR, Fonseca VA.

Metabolism. 2001 Sep;50(9):1014-8.

PMID:
11555831
48.
49.

Is testing for inherited coagulation inhibitor deficiencies in young stroke patients worthwhile?

Amiri M, Schmidley JW, Fink LM, Nazarian SM.

Clin Neurol Neurosurg. 2000 Dec;102(4):219-222.

PMID:
11154808
50.

Selection and implementation for coagulation instruments/reagents in a multiple hospital/clinic network.

Cary ER, Fink LM, Stokes SL, Simmons VL, Kaczor DA, Harmon S, Quarles L, Escobar C, Maier DJ.

Blood Coagul Fibrinolysis. 2000 Oct;11(7):599-608.

PMID:
11085279

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