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Items: 1 to 50 of 231

1.

Erratum: Author Correction: Age-associated changes in the impact of sex steroids on influenza vaccine responses in males and females.

Potluri T, Fink AL, Sylvia KE, Dhakal S, Vermillion MS, Vom Steeg L, Deshpande S, Narasimhan H, Klein SL.

NPJ Vaccines. 2019 Aug 12;4:35. doi: 10.1038/s41541-019-0130-8. eCollection 2019.

2.

Age-associated changes in the impact of sex steroids on influenza vaccine responses in males and females.

Potluri T, Fink AL, Sylvia KE, Dhakal S, Vermillion MS, Vom Steeg L, Deshpande S, Narasimhan H, Klein SL.

NPJ Vaccines. 2019 Jul 12;4:29. doi: 10.1038/s41541-019-0124-6. eCollection 2019. Erratum in: NPJ Vaccines. 2019 Aug 12;4:35.

3.

PI3K/AKT/mTOR Pathway Alterations Promote Malignant Progression and Xenograft Formation in Oligodendroglial Tumors.

Tateishi K, Nakamura T, Juratli TA, Williams EA, Matsushita Y, Miyake S, Nishi M, Miller JJ, Tummala SS, Fink AL, Lelic N, Koerner MVA, Miyake Y, Sasame J, Fujimoto K, Tanaka T, Minamimoto R, Matsunaga S, Mukaihara S, Shuto T, Taguchi H, Udaka N, Murata H, Ryo A, Yamanaka S, Curry WT, Dias-Santagata D, Yamamoto T, Ichimura K, Batchelor TT, Chi AS, Iafrate AJ, Wakimoto H, Cahill DP.

Clin Cancer Res. 2019 Jul 15;25(14):4375-4387. doi: 10.1158/1078-0432.CCR-18-4144. Epub 2019 Apr 11.

PMID:
30975663
4.

The Dual PI3K/mTOR Pathway Inhibitor GDC-0084 Achieves Antitumor Activity in PIK3CA-Mutant Breast Cancer Brain Metastases.

Ippen FM, Alvarez-Breckenridge CA, Kuter BM, Fink AL, Bihun IV, Lastrapes M, Penson T, Schmidt SP, Wojtkiewicz GR, Ning J, Subramanian M, Giobbie-Hurder A, Martinez-Lage M, Carter SL, Cahill DP, Wakimoto H, Brastianos PK.

Clin Cancer Res. 2019 Jun 1;25(11):3374-3383. doi: 10.1158/1078-0432.CCR-18-3049. Epub 2019 Feb 22.

PMID:
30796030
5.

A Clinical Rule for Preoperative Prediction of BRAF Mutation Status in Craniopharyngiomas.

Fujio S, Juratli TA, Arita K, Hirano H, Nagano Y, Takajo T, Yoshimoto K, Bihun IV, Kaplan AB, Nayyar N, Fink AL, Bertalan MS, Tummala SS, Curry WT Jr, Jones PS, Martinez-Lage M, Cahill DP, Barker FG, Brastianos PK.

Neurosurgery. 2019 Aug 1;85(2):204-210. doi: 10.1093/neuros/nyy569.

PMID:
30481321
6.

Biological sex affects vaccine efficacy and protection against influenza in mice.

Fink AL, Engle K, Ursin RL, Tang WY, Klein SL.

Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):12477-12482. doi: 10.1073/pnas.1805268115. Epub 2018 Nov 19.

7.

The evolution of greater humoral immunity in females than males: implications for vaccine efficacy.

Fink AL, Klein SL.

Curr Opin Physiol. 2018 Dec;6:16-20. doi: 10.1016/j.cophys.2018.03.010. Epub 2018 Mar 29.

PMID:
30320243
8.

PLK1 Inhibition Targets Myc-Activated Malignant Glioma Cells Irrespective of Mismatch Repair Deficiency-Mediated Acquired Resistance to Temozolomide.

Higuchi F, Fink AL, Kiyokawa J, Miller JJ, Koerner MVA, Cahill DP, Wakimoto H.

Mol Cancer Ther. 2018 Dec;17(12):2551-2563. doi: 10.1158/1535-7163.MCT-18-0177. Epub 2018 Sep 14.

9.

DMD genomic deletions characterize a subset of progressive/higher-grade meningiomas with poor outcome.

Juratli TA, McCabe D, Nayyar N, Williams EA, Silverman IM, Tummala SS, Fink AL, Baig A, Martinez-Lage M, Selig MK, Bihun IV, Shankar GM, Penson T, Lastrapes M, Daubner D, Meinhardt M, Hennig S, Kaplan AB, Fujio S, Kuter BM, Bertalan MS, Miller JJ, Batten JM, Ely HA, Christiansen J, Baretton GB, Stemmer-Rachamimov AO, Santagata S, Rivera MN, Barker FG 2nd, Schackert G, Wakimoto H, Iafrate AJ, Carter SL, Cahill DP, Brastianos PK.

Acta Neuropathol. 2018 Nov;136(5):779-792. doi: 10.1007/s00401-018-1899-7. Epub 2018 Aug 19.

PMID:
30123936
10.

Genotype-targeted local therapy of glioma.

Shankar GM, Kirtane AR, Miller JJ, Mazdiyasni H, Rogner J, Tai T, Williams EA, Higuchi F, Juratli TA, Tateishi K, Koerner MVA, Tummala SS, Fink AL, Penson T, Schmidt SP, Wojtkiewicz GR, Baig A, Francis JM, Rinne ML, Batten JM, Batchelor TT, Brastianos PK, Curry WT Jr, Barker FG 2nd, Jordan JT, Iafrate AJ, Chi AS, Lennerz JK, Meyerson M, Langer R, Wakimoto H, Traverso G, Cahill DP.

Proc Natl Acad Sci U S A. 2018 Sep 4;115(36):E8388-E8394. doi: 10.1073/pnas.1805751115. Epub 2018 Aug 6.

11.

Production of amphiregulin and recovery from influenza is greater in males than females.

Vermillion MS, Ursin RL, Kuok DIT, Vom Steeg LG, Wohlgemuth N, Hall OJ, Fink AL, Sasse E, Nelson A, Ndeh R, McGrath-Morrow S, Mitzner W, Chan MCW, Pekosz A, Klein SL.

Biol Sex Differ. 2018 Jul 17;9(1):24. doi: 10.1186/s13293-018-0184-8.

12.

The Confluence of Sex Hormones and Aging on Immunity.

Gubbels Bupp MR, Potluri T, Fink AL, Klein SL.

Front Immunol. 2018 Jun 4;9:1269. doi: 10.3389/fimmu.2018.01269. eCollection 2018. Review.

13.

Sex Reporting in Preclinical Microbiological and Immunological Research.

Potluri T, Engle K, Fink AL, Vom Steeg LG, Klein SL.

MBio. 2017 Nov 14;8(6). pii: e01868-17. doi: 10.1128/mBio.01868-17.

14.

Sex and Gender Differences in the Outcomes of Vaccination over the Life Course.

Flanagan KL, Fink AL, Plebanski M, Klein SL.

Annu Rev Cell Dev Biol. 2017 Oct 6;33:577-599. doi: 10.1146/annurev-cellbio-100616-060718. Review.

PMID:
28992436
15.

Dengue virus specific IgY provides protection following lethal dengue virus challenge and is neutralizing in the absence of inducing antibody dependent enhancement.

Fink AL, Williams KL, Harris E, Alvine TD, Henderson T, Schiltz J, Nilles ML, Bradley DS.

PLoS Negl Trop Dis. 2017 Jul 7;11(7):e0005721. doi: 10.1371/journal.pntd.0005721. eCollection 2017 Jul.

16.

Progesterone-Based Contraceptives Reduce Adaptive Immune Responses and Protection against Sequential Influenza A Virus Infections.

Hall OJ, Nachbagauer R, Vermillion MS, Fink AL, Phuong V, Krammer F, Klein SL.

J Virol. 2017 Mar 29;91(8). pii: e02160-16. doi: 10.1128/JVI.02160-16. Print 2017 Apr 15.

17.

Sex and Gender Impact Immune Responses to Vaccines Among the Elderly.

Fink AL, Klein SL.

Physiology (Bethesda). 2015 Nov;30(6):408-16. doi: 10.1152/physiol.00035.2015. Review.

18.

Distinct β-sheet structure in protein aggregates determined by ATR-FTIR spectroscopy.

Shivu B, Seshadri S, Li J, Oberg KA, Uversky VN, Fink AL.

Biochemistry. 2013 Aug 6;52(31):5176-83. doi: 10.1021/bi400625v. Epub 2013 Jul 22.

PMID:
23837615
19.

Oxidized quercetin inhibits α-synuclein fibrillization.

Zhu M, Han S, Fink AL.

Biochim Biophys Acta. 2013 Apr;1830(4):2872-81. doi: 10.1016/j.bbagen.2012.12.027. Epub 2013 Jan 4.

PMID:
23295967
20.

Biophysical Characterization of α-Synuclein and Rotenone Interaction.

Silva BA, Einarsdóttir O, Fink AL, Uversky VN.

Biomolecules. 2013 Sep 24;3(3):703-32. doi: 10.3390/biom3030703.

21.

Agrochemicals, α-synuclein, and Parkinson's disease.

Silva BA, Breydo L, Fink AL, Uversky VN.

Mol Neurobiol. 2013 Apr;47(2):598-612. doi: 10.1007/s12035-012-8333-2. Epub 2012 Aug 30. Review.

PMID:
22933040
22.

Peculiarities of copper binding to alpha-synuclein.

Ahmad A, Burns CS, Fink AL, Uversky VN.

J Biomol Struct Dyn. 2012;29(4):825-42.

PMID:
22208282
23.

Conserved C-terminal charge exerts a profound influence on the aggregation rate of α-synuclein.

Levitan K, Chereau D, Cohen SI, Knowles TP, Dobson CM, Fink AL, Anderson JP, Goldstein JM, Millhauser GL.

J Mol Biol. 2011 Aug 12;411(2):329-33. doi: 10.1016/j.jmb.2011.05.046. Epub 2011 Jun 12.

24.

Effects of Various Flavonoids on the α-Synuclein Fibrillation Process.

Meng X, Munishkina LA, Fink AL, Uversky VN.

Parkinsons Dis. 2010 Jan 28;2010:650794. doi: 10.4061/2010/650794.

25.

Characterization of the non-fibrillar α-synuclein oligomers.

Hong DP, Han S, Fink AL, Uversky VN.

Protein Pept Lett. 2011 Mar;18(3):230-40.

PMID:
20858207
26.

Methionine oxidation stabilizes non-toxic oligomers of alpha-synuclein through strengthening the auto-inhibitory intra-molecular long-range interactions.

Zhou W, Long C, Reaney SH, Di Monte DA, Fink AL, Uversky VN.

Biochim Biophys Acta. 2010 Mar;1802(3):322-30. doi: 10.1016/j.bbadis.2009.12.004. Epub 2009 Dec 21.

27.

Molecular mechanisms underlying the flavonoid-induced inhibition of alpha-synuclein fibrillation.

Meng X, Munishkina LA, Fink AL, Uversky VN.

Biochemistry. 2009 Sep 1;48(34):8206-24. doi: 10.1021/bi900506b.

PMID:
19634918
28.
29.

At low concentrations, 3,4-dihydroxyphenylacetic acid (DOPAC) binds non-covalently to alpha-synuclein and prevents its fibrillation.

Zhou W, Gallagher A, Hong DP, Long C, Fink AL, Uversky VN.

J Mol Biol. 2009 May 8;388(3):597-610. doi: 10.1016/j.jmb.2009.03.053. Epub 2009 Mar 25.

30.

Concerted action of metals and macromolecular crowding on the fibrillation of alpha-synuclein.

Munishkina LA, Fink AL, Uversky VN.

Protein Pept Lett. 2008;15(10):1079-85.

31.

Smoking and Parkinson's disease: does nicotine affect alpha-synuclein fibrillation?

Hong DP, Fink AL, Uversky VN.

Biochim Biophys Acta. 2009 Feb;1794(2):282-90. doi: 10.1016/j.bbapap.2008.09.026. Epub 2008 Oct 25.

32.

Structural characteristics of alpha-synuclein oligomers stabilized by the flavonoid baicalein.

Hong DP, Fink AL, Uversky VN.

J Mol Biol. 2008 Oct 31;383(1):214-23. doi: 10.1016/j.jmb.2008.08.039. Epub 2008 Aug 23.

33.

Impact of Tyr to Ala mutations on alpha-synuclein fibrillation and structural properties.

Ulrih NP, Barry CH, Fink AL.

Biochim Biophys Acta. 2008 Oct;1782(10):581-5. doi: 10.1016/j.bbadis.2008.07.004. Epub 2008 Jul 22.

34.

Guiding protein aggregation with macromolecular crowding.

Munishkina LA, Ahmad A, Fink AL, Uversky VN.

Biochemistry. 2008 Aug 26;47(34):8993-9006. doi: 10.1021/bi8008399. Epub 2008 Jul 30.

35.

Effect of methionine oxidation on the structural properties, conformational stability, and aggregation of immunoglobulin light chain LEN.

Hu D, Qin Z, Xue B, Fink AL, Uversky VN.

Biochemistry. 2008 Aug 19;47(33):8665-77. doi: 10.1021/bi800806d. Epub 2008 Jul 25.

36.

The effect of membranes on the in vitro fibrillation of an amyloidogenic light-chain variable-domain SMA.

Meng X, Fink AL, Uversky VN.

J Mol Biol. 2008 Sep 12;381(4):989-99. doi: 10.1016/j.jmb.2008.06.062. Epub 2008 Jun 28.

37.

Structural impact of three Parkinsonism-associated missense mutations on human DJ-1.

Lakshminarasimhan M, Maldonado MT, Zhou W, Fink AL, Wilson MA.

Biochemistry. 2008 Feb 5;47(5):1381-92. doi: 10.1021/bi701189c. Epub 2008 Jan 9.

38.

Role of different regions of alpha-synuclein in the assembly of fibrils.

Qin Z, Hu D, Han S, Hong DP, Fink AL.

Biochemistry. 2007 Nov 20;46(46):13322-30. Epub 2007 Oct 27.

PMID:
17963364
39.

Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins.

Munishkina LA, Fink AL.

Biochim Biophys Acta. 2007 Aug;1768(8):1862-85. Epub 2007 Mar 28. Review.

40.
41.

GM1 specifically interacts with alpha-synuclein and inhibits fibrillation.

Martinez Z, Zhu M, Han S, Fink AL.

Biochemistry. 2007 Feb 20;46(7):1868-77. Epub 2007 Jan 25.

PMID:
17253773
42.

Effect of 4-hydroxy-2-nonenal modification on alpha-synuclein aggregation.

Qin Z, Hu D, Han S, Reaney SH, Di Monte DA, Fink AL.

J Biol Chem. 2007 Feb 23;282(8):5862-70. Epub 2006 Dec 21.

43.

The aggregation and fibrillation of alpha-synuclein.

Fink AL.

Acc Chem Res. 2006 Sep;39(9):628-34. Review.

PMID:
16981679
44.

Fibrillation of human insulin A and B chains.

Hong DP, Ahmad A, Fink AL.

Biochemistry. 2006 Aug 1;45(30):9342-53.

PMID:
16866381
45.

Alpha-synuclein can function as an antioxidant preventing oxidation of unsaturated lipid in vesicles.

Zhu M, Qin ZJ, Hu D, Munishkina LA, Fink AL.

Biochemistry. 2006 Jul 4;45(26):8135-42.

PMID:
16800638
46.

Characterization of oligomers during alpha-synuclein aggregation using intrinsic tryptophan fluorescence.

Dusa A, Kaylor J, Edridge S, Bodner N, Hong DP, Fink AL.

Biochemistry. 2006 Feb 28;45(8):2752-60.

PMID:
16489768
47.

The oxidation state of DJ-1 regulates its chaperone activity toward alpha-synuclein.

Zhou W, Zhu M, Wilson MA, Petsko GA, Fink AL.

J Mol Biol. 2006 Mar 3;356(4):1036-48. Epub 2005 Dec 27.

PMID:
16403519
48.

Independent heterologous fibrillation of insulin and its B-chain peptide.

Hong DP, Fink AL.

Biochemistry. 2005 Dec 20;44(50):16701-9.

PMID:
16342960
49.

Early events in the fibrillation of monomeric insulin.

Ahmad A, Uversky VN, Hong D, Fink AL.

J Biol Chem. 2005 Dec 30;280(52):42669-75. Epub 2005 Oct 24.

50.

Characterization of oligomeric intermediates in alpha-synuclein fibrillation: FRET studies of Y125W/Y133F/Y136F alpha-synuclein.

Kaylor J, Bodner N, Edridge S, Yamin G, Hong DP, Fink AL.

J Mol Biol. 2005 Oct 21;353(2):357-72.

PMID:
16171820

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