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Membrane-associated mucins of the ocular surface: New genes, new protein functions and new biological roles in human and mouse.

Fini ME, Jeong S, Gong H, Martinez-Carrasco R, Laver NMV, Hijikata M, Keicho N, Argüeso P.

Prog Retin Eye Res. 2019 Sep 4:100777. doi: 10.1016/j.preteyeres.2019.100777. [Epub ahead of print] Review.


GPR158 in the Visual System: Homeostatic Role in Regulation of Intraocular Pressure.

Itakura T, Webster A, Chintala SK, Wang Y, Gonzalez JM Jr, Tan JC, Vranka JA, Acott T, Craft CM, Sibug Saber ME, Jeong S, Stamer WD, Martemyanov KA, Fini ME.

J Ocul Pharmacol Ther. 2019 May;35(4):203-215. doi: 10.1089/jop.2018.0135. Epub 2019 Mar 18.


Dynasore protects the ocular surface against damaging oxidative stress.

Webster A, Chintala SK, Kim J, Ngan M, Itakura T, Panjwani N, Argüeso P, Barr JT, Jeong S, Fini ME.

PLoS One. 2018 Oct 10;13(10):e0204288. doi: 10.1371/journal.pone.0204288. eCollection 2018. Erratum in: PLoS One. 2018 Dec 5;13(12):e0208864.


Clusterin from human clinical tear samples: Positive correlation between tear concentration and Schirmer strip test results.

Yu V, Bhattacharya D, Webster A, Bauskar A, Flowers C, Heur M, Chintala SK, Itakura T, Wilson MR, Barr JT, Jeong S, Wang M, Fini ME.

Ocul Surf. 2018 Oct;16(4):478-486. doi: 10.1016/j.jtos.2018.08.001. Epub 2018 Aug 2.


Induction and Quantification of Excitability Changes in Human Cortical Networks.

Keller CJ, Huang Y, Herrero JL, Fini ME, Du V, Lado FA, Honey CJ, Mehta AD.

J Neurosci. 2018 Jun 6;38(23):5384-5398. doi: 10.1523/JNEUROSCI.1088-17.2018. Epub 2018 May 21.


Another Piece of the Puzzle: MYOC and Myocilin Glaucoma.

Fini ME.

Invest Ophthalmol Vis Sci. 2017 Oct 1;58(12):5319. doi: 10.1167/iovs.17-23045. No abstract available.


Steroid-induced ocular hypertension/glaucoma: Focus on pharmacogenomics and implications for precision medicine.

Fini ME, Schwartz SG, Gao X, Jeong S, Patel N, Itakura T, Price MO, Price FW Jr, Varma R, Stamer WD.

Prog Retin Eye Res. 2017 Jan;56:58-83. doi: 10.1016/j.preteyeres.2016.09.003. Epub 2016 Sep 22. Review.


Clusterin in the eye: An old dog with new tricks at the ocular surface.

Fini ME, Bauskar A, Jeong S, Wilson MR.

Exp Eye Res. 2016 Jun;147:57-71. doi: 10.1016/j.exer.2016.04.019. Epub 2016 Apr 27. Review.


A cell-based screening assay to identify pharmaceutical compounds that enhance the regenerative quality of corneal repair.

Gordon GM, LaGier AJ, Ponchel C, Bauskar A, Itakura T, Jeong S, Patel N, Fini ME.

Wound Repair Regen. 2016 Jan-Feb;24(1):89-99. doi: 10.1111/wrr.12390. Epub 2016 Jan 5.


Mining Retrospective Data for Virtual Prospective Drug Repurposing: L-DOPA and Age-related Macular Degeneration.

Brilliant MH, Vaziri K, Connor TB Jr, Schwartz SG, Carroll JJ, McCarty CA, Schrodi SJ, Hebbring SJ, Kishor KS, Flynn HW Jr, Moshfeghi AA, Moshfeghi DM, Fini ME, McKay BS.

Am J Med. 2016 Mar;129(3):292-8. doi: 10.1016/j.amjmed.2015.10.015. Epub 2015 Oct 30.


Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye.

Bauskar A, Mack WJ, Mauris J, Argüeso P, Heur M, Nagel BA, Kolar GR, Gleave ME, Nakamura T, Kinoshita S, Moradian-Oldak J, Panjwani N, Pflugfelder SC, Wilson MR, Fini ME, Jeong S.

PLoS One. 2015 Sep 24;10(9):e0138958. doi: 10.1371/journal.pone.0138958. eCollection 2015.


Identification of a Novel Mucin Gene HCG22 Associated With Steroid-Induced Ocular Hypertension.

Jeong S, Patel N, Edlund CK, Hartiala J, Hazelett DJ, Itakura T, Wu PC, Avery RL, Davis JL, Flynn HW, Lalwani G, Puliafito CA, Wafapoor H, Hijikata M, Keicho N, Gao X, Argüeso P, Allayee H, Coetzee GA, Pletcher MT, Conti DV, Schwartz SG, Eaton AM, Fini ME.

Invest Ophthalmol Vis Sci. 2015 Apr;56(4):2737-48. doi: 10.1167/iovs.14-14803.


Expression and functional role of orphan receptor GPR158 in prostate cancer growth and progression.

Patel N, Itakura T, Jeong S, Liao CP, Roy-Burman P, Zandi E, Groshen S, Pinski J, Coetzee GA, Gross ME, Fini ME.

PLoS One. 2015 Feb 18;10(2):e0117758. doi: 10.1371/journal.pone.0117758. eCollection 2015.


Chondrogenesis in scleral stem/progenitor cells and its association with form-deprived myopia in mice.

Wu PC, Tsai CL, Gordon GM, Jeong S, Itakura T, Patel N, Shi S, Fini ME.

Mol Vis. 2015 Feb 6;21:138-47. eCollection 2015.


Lacritin-mediated regeneration of the corneal epithelia by protein polymer nanoparticles.

Wang W, Despanie J, Shi P, Edman-Woolcott MC, Lin YA, Cui H, Heur JM, Fini ME, Hamm-Alvarez SF, MacKay JA.

J Mater Chem B. 2014 Dec 14;2(46):8131-8141.


Prevalence and severity of depression and anxiety in patients with systemic lupus erythematosus: An epidemiologic study in Iranian patients.

Kheirandish M, Faezi ST, Paragomi P, Akhlaghi M, Gharibdoost F, Shahali A, Fini ME, Akbarian M.

Mod Rheumatol. 2015 May;25(3):405-9. doi: 10.3109/14397595.2014.962241. Epub 2014 Oct 8.


Mechanisms for PDGF, a serum cytokine, stimulating loss of corneal keratocyte crystallins.

LaGier AJ, Gordon GM, Katzman LR, Vasiliou V, Fini ME.

Cornea. 2013 Sep;32(9):1269-75. doi: 10.1097/ICO.0b013e318296e0b9.


GPR158, an orphan member of G protein-coupled receptor Family C: glucocorticoid-stimulated expression and novel nuclear role.

Patel N, Itakura T, Gonzalez JM Jr, Schwartz SG, Fini ME.

PLoS One. 2013;8(2):e57843. doi: 10.1371/journal.pone.0057843. Epub 2013 Feb 25.


β1 integrin-focal adhesion kinase (FAK) signaling modulates retinal ganglion cell (RGC) survival.

Santos AR, Corredor RG, Obeso BA, Trakhtenberg EF, Wang Y, Ponmattam J, Dvoriantchikova G, Ivanov D, Shestopalov VI, Goldberg JL, Fini ME, Bajenaru ML.

PLoS One. 2012;7(10):e48332. doi: 10.1371/journal.pone.0048332. Epub 2012 Oct 31.


Interaction of clusterin and matrix metalloproteinase-9 and its implication for epithelial homeostasis and inflammation.

Jeong S, Ledee DR, Gordon GM, Itakura T, Patel N, Martin A, Fini ME.

Am J Pathol. 2012 May;180(5):2028-39. doi: 10.1016/j.ajpath.2012.01.025. Epub 2012 Mar 20.


Single-shot dimension measurements of the mouse eye using SD-OCT.

Jiang M, Wu PC, Fini ME, Tsai CL, Itakura T, Zhang X, Jiao S.

Ophthalmic Surg Lasers Imaging. 2012 May-Jun;43(3):252-6. doi: 10.3928/15428877-20120308-04. Epub 2012 Mar 15.


A novel mechanism of increased infections in contact lens wearers.

Gordon GM, Moradshahi N, Jeong S, Lane C, Fini ME.

Invest Ophthalmol Vis Sci. 2011 Nov 25;52(12):9188-94. doi: 10.1167/iovs.11-7658.


Identification of multipotent stem/progenitor cells in murine sclera.

Tsai CL, Wu PC, Fini ME, Shi S.

Invest Ophthalmol Vis Sci. 2011 Jul 25;52(8):5481-7. doi: 10.1167/iovs.11-7676.


Correlation between epithelial ingrowth and basement membrane remodeling in human corneas after laser-assisted in situ keratomileusis.

Fournié PR, Gordon GM, Dawson DG, Malecaze FJ, Edelhauser HF, Fini ME.

Arch Ophthalmol. 2010 Apr;128(4):426-36. doi: 10.1001/archophthalmol.2010.23.


Isoform- and dose-sensitive feedback interactions between paired box 6 gene and delta-catenin in cell differentiation and death.

Zhang J, Lu JP, Suter DM, Krause KH, Fini ME, Chen B, Lu Q.

Exp Cell Res. 2010 Apr 1;316(6):1070-81. doi: 10.1016/j.yexcr.2010.01.006. Epub 2010 Jan 11.


Cytokines and signaling pathways regulating matrix metalloproteinase-9 (MMP-9) expression in corneal epithelial cells.

Gordon GM, Ledee DR, Feuer WJ, Fini ME.

J Cell Physiol. 2009 Nov;221(2):402-11. doi: 10.1002/jcp.21869.


Molecular identification of t4 and t5 genotypes in isolates from acanthamoeba keratitis patients.

Ledee DR, Iovieno A, Miller D, Mandal N, Diaz M, Fell J, Fini ME, Alfonso EC.

J Clin Microbiol. 2009 May;47(5):1458-62. doi: 10.1128/JCM.02365-08. Epub 2009 Mar 25.


Collagen fibril growth during chicken tendon development: matrix metalloproteinase-2 and its activation.

Jung JC, Wang PX, Zhang G, Ezura Y, Fini ME, Birk DE.

Cell Tissue Res. 2009 Apr;336(1):79-89. doi: 10.1007/s00441-009-0755-4. Epub 2009 Feb 17.


Utility of molecular sequence analysis of the ITS rRNA region for identification of Fusarium spp. from ocular sources.

Oechsler RA, Feilmeier MR, Ledee DR, Miller D, Diaz MR, Fini ME, Fell JW, Alfonso EC.

Invest Ophthalmol Vis Sci. 2009 May;50(5):2230-6. doi: 10.1167/iovs.08-2757. Epub 2009 Jan 10.


Glucocorticoid receptor polymorphisms and intraocular pressure response to intravitreal triamcinolone acetonide.

Gerzenstein SM, Pletcher MT, Cervino AC, Tsinoremas NF, Young B, Puliafito CA, Fini ME, Schwartz SG.

Ophthalmic Genet. 2008 Dec;29(4):166-70. doi: 10.1080/13816810802320217.


Identification of E2F1 as a positive transcriptional regulator for delta-catenin.

Kim K, Oh M, Ki H, Wang T, Bareiss S, Fini ME, Li D, Lu Q.

Biochem Biophys Res Commun. 2008 May 2;369(2):414-20. doi: 10.1016/j.bbrc.2008.02.069. Epub 2008 Feb 25.


Correlations of long-term matrix metalloproteinase localization in human corneas after successful laser-assisted in situ keratomileusis with minor complications at the flap margin.

Fournié PR, Gordon GM, Dawson DG, Edelhauser HF, Fini ME.

Arch Ophthalmol. 2008 Feb;126(2):162-70. doi: 10.1001/archophthalmol.2007.64.


Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development.

Bassett EA, Pontoriero GF, Feng W, Marquardt T, Fini ME, Williams T, West-Mays JA.

Mol Cell Biol. 2007 Nov;27(21):7497-510. Epub 2007 Aug 27.


Retinoblastoma tumor vessel maturation impacts efficacy of vessel targeting in the LH(BETA)T(AG) mouse model.

Jockovich ME, Bajenaru ML, Piña Y, Suarez F, Feuer W, Fini ME, Murray TG.

Invest Ophthalmol Vis Sci. 2007 Jun;48(6):2476-82.


Inhibition of human corneal epithelial production of fibrotic mediator TGF-beta2 by basement membrane-like extracellular matrix.

LaGier AJ, Yoo SH, Alfonso EC, Meiners S, Fini ME.

Invest Ophthalmol Vis Sci. 2007 Mar;48(3):1061-71.


Roles of MMP/TIMP in regulating matrix swelling and cell migration during chick corneal development.

Huh MI, Lee YM, Seo SK, Kang BS, Chang Y, Lee YS, Fini ME, Kang SS, Jung JC.

J Cell Biochem. 2007 Aug 1;101(5):1222-37.


Selective spatiotemporal induction of matrix metalloproteinase-2 and matrix metalloproteinase-9 transcription after myocardial infarction.

Mukherjee R, Mingoia JT, Bruce JA, Austin JS, Stroud RE, Escobar GP, McClister DM Jr, Allen CM, Alfonso-Jaume MA, Fini ME, Lovett DH, Spinale FG.

Am J Physiol Heart Circ Physiol. 2006 Nov;291(5):H2216-28. Epub 2006 Jun 9.


Pax6 overexpression suppresses cell proliferation and retards the cell cycle in corneal epithelial cells.

Ouyang J, Shen YC, Yeh LK, Li W, Coyle BM, Liu CY, Fini ME.

Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2397-407.


Constitutive signalling pathway activity in trabecular meshwork cells from glaucomatous eyes.

Zhang X, Schroeder A, Callahan EM, Coyle BM, Wang N, Erickson KA, Schuman JS, Fini ME.

Exp Eye Res. 2006 Jun;82(6):968-73. Epub 2006 Mar 3.


How the cornea heals: cornea-specific repair mechanisms affecting surgical outcomes.

Fini ME, Stramer BM.

Cornea. 2005 Nov;24(8 Suppl):S2-S11. Review.


Matrix metalloproteinase gelatinase B (MMP-9) is associated with leaking glaucoma filtering blebs.

Chintala SK, Wang N, Diskin S, Mattox C, Kagemann L, Fini ME, Schuman JS.

Exp Eye Res. 2005 Oct;81(4):429-36.


Matrix metalloproteinase-9 knockout confers resistance to corneal epithelial barrier disruption in experimental dry eye.

Pflugfelder SC, Farley W, Luo L, Chen LZ, de Paiva CS, Olmos LC, Li DQ, Fini ME.

Am J Pathol. 2005 Jan;166(1):61-71.


Selective reduction of fibrotic markers in repairing corneas of mice deficient in Smad3.

Stramer BM, Austin JS, Roberts AB, Fini ME.

J Cell Physiol. 2005 Apr;203(1):226-32.


Uncoupling keratocyte loss of corneal crystallin from markers of fibrotic repair.

Stramer BM, Fini ME.

Invest Ophthalmol Vis Sci. 2004 Nov;45(11):4010-5.


Activity and expression of Xenopus laevis matrix metalloproteinases: identification of a novel role for the hormone prolactin in regulating collagenolysis in both amphibians and mammals.

Jung JC, West-Mays JA, Stramer BM, Byrne MH, Scott S, Mody MK, Sadow PM, Krane SM, Fini ME.

J Cell Physiol. 2004 Oct;201(1):155-64. Erratum in: J Cell Physiol. 2004 Oct;201(1):165.


Monoclonal antibody (3G5)-defined ganglioside: cell surface marker of corneal keratocytes.

Stramer BM, Kwok MG, Farthing-Nayak PJ, Jung JC, Fini ME, Nayak RC.

Invest Ophthalmol Vis Sci. 2004 Mar;45(3):807-12.


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