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Items: 20

1.

Immunoglobulin-driven Complement Activation Regulates Proinflammatory Remodeling in Pulmonary Hypertension.

Frid MG, McKeon BA, Thurman JM, Maron BA, Li M, Zhang H, Kumar S, Sullivan T, Laskowsky J, Fini MA, Hu S, Tuder RM, Gandjeva A, Wilkins MR, Rhodes CJ, Ghataorhe P, Leopold JA, Wang RS, Holers VM, Stenmark KR.

Am J Respir Crit Care Med. 2020 Jan 15;201(2):224-239. doi: 10.1164/rccm.201903-0591OC.

PMID:
31545648
2.

Pegloticase and lowering blood pressure in refractory gout; is it uric acid or hydrogen peroxide?

Fini MA, Stenmark KR.

Eur J Intern Med. 2019 Nov;69:e11-e12. doi: 10.1016/j.ejim.2019.08.017. Epub 2019 Aug 27. No abstract available.

PMID:
31471165
3.

An Hb-mediated circulating macrophage contributing to pulmonary vascular remodeling in sickle cell disease.

Redinus K, Baek JH, Yalamanoglu A, Shin HKH, Moldova R, Harral JW, Swindle D, Pak D, Ferguson SK, Nuss R, Hassell K, Nozik-Grayck E, Palmer AF, Fini MA, Karoor V, Stenmark KR, Buehler PW, Irwin DC.

JCI Insight. 2019 Aug 8;4(15). pii: 127860. doi: 10.1172/jci.insight.127860. eCollection 2019 Aug 8.

4.

Sustained Activation of Rho GTPases Promotes a Synthetic Pulmonary Artery Smooth Muscle Cell Phenotype in Neprilysin Null Mice.

Karoor V, Fini MA, Loomis Z, Sullivan T, Hersh LB, Gerasimovskaya E, Irwin D, Dempsey EC.

Arterioscler Thromb Vasc Biol. 2018 Jan;38(1):154-163. doi: 10.1161/ATVBAHA.117.310207. Epub 2017 Nov 30.

5.

Alcohol abuse is associated with enhanced pulmonary and systemic xanthine oxidoreductase activity.

Fini MA, Gaydos J, McNally A, Karoor V, Burnham EL.

Am J Physiol Lung Cell Mol Physiol. 2017 Dec 1;313(6):L1047-L1057. doi: 10.1152/ajplung.00570.2016. Epub 2017 Aug 24.

6.

Metabolic Reprogramming Regulates the Proliferative and Inflammatory Phenotype of Adventitial Fibroblasts in Pulmonary Hypertension Through the Transcriptional Corepressor C-Terminal Binding Protein-1.

Li M, Riddle S, Zhang H, D'Alessandro A, Flockton A, Serkova NJ, Hansen KC, Moldovan R, McKeon BA, Frid M, Kumar S, Li H, Liu H, Caánovas A, Medrano JF, Thomas MG, Iloska D, Plecitá-Hlavatá L, Ježek P, Pullamsetti S, Fini MA, El Kasmi KC, Zhang Q, Stenmark KR.

Circulation. 2016 Oct 11;134(15):1105-1121. Epub 2016 Aug 25. Erratum in: Circulation. 2019 Jan 8;139(2):e1. Moldvan, Radu [corrected to Moldovan, Radu].

7.

The role of inflammation in hypoxic pulmonary hypertension: from cellular mechanisms to clinical phenotypes.

Pugliese SC, Poth JM, Fini MA, Olschewski A, El Kasmi KC, Stenmark KR.

Am J Physiol Lung Cell Mol Physiol. 2015 Feb 1;308(3):L229-52. doi: 10.1152/ajplung.00238.2014. Epub 2014 Nov 21. Review.

8.

Adventitial fibroblasts induce a distinct proinflammatory/profibrotic macrophage phenotype in pulmonary hypertension.

El Kasmi KC, Pugliese SC, Riddle SR, Poth JM, Anderson AL, Frid MG, Li M, Pullamsetti SS, Savai R, Nagel MA, Fini MA, Graham BB, Tuder RM, Friedman JE, Eltzschig HK, Sokol RJ, Stenmark KR.

J Immunol. 2014 Jul 15;193(2):597-609. doi: 10.4049/jimmunol.1303048. Epub 2014 Jun 13.

9.

Is uric acid an underdiagnosed mediator of adverse outcome in metabolically healthy overweight/obese individuals?

Fini MA, Wright RM, Stenmark KR, Daniels SR, Johnson RJ.

Am J Med. 2014 Jun;127(6):e21. doi: 10.1016/j.amjmed.2014.02.031. No abstract available.

10.

MicroRNA-124 controls the proliferative, migratory, and inflammatory phenotype of pulmonary vascular fibroblasts.

Wang D, Zhang H, Li M, Frid MG, Flockton AR, McKeon BA, Yeager ME, Fini MA, Morrell NW, Pullamsetti SS, Velegala S, Seeger W, McKinsey TA, Sucharov CC, Stenmark KR.

Circ Res. 2014 Jan 3;114(1):67-78. doi: 10.1161/CIRCRESAHA.114.301633. Epub 2013 Oct 11.

11.

Hypertension, nitrate-nitrite, and xanthine oxidoreductase catalyzed nitric oxide generation: pros and cons.

Fini MA, Johnson RJ, Stenmark KR, Wright RM.

Hypertension. 2013 Sep;62(3):e9. doi: 10.1161/HYPERTENSIONAHA.113.01826. Epub 2013 Jul 29. No abstract available.

PMID:
23897071
12.

Contribution of uric acid to cancer risk, recurrence, and mortality.

Fini MA, Elias A, Johnson RJ, Wright RM.

Clin Transl Med. 2012 Aug 15;1(1):16. doi: 10.1186/2001-1326-1-16.

13.

Osteopontin is an endogenous modulator of the constitutively activated phenotype of pulmonary adventitial fibroblasts in hypoxic pulmonary hypertension.

Anwar A, Li M, Frid MG, Kumar B, Gerasimovskaya EV, Riddle SR, McKeon BA, Thukaram R, Meyrick BO, Fini MA, Stenmark KR.

Am J Physiol Lung Cell Mol Physiol. 2012 Jul 1;303(1):L1-L11. doi: 10.1152/ajplung.00050.2012. Epub 2012 May 11.

14.

Contribution of xanthine oxidoreductase to mammary epithelial and breast cancer cell differentiation in part modulates inhibitor of differentiation-1.

Fini MA, Monks J, Farabaugh SM, Wright RM.

Mol Cancer Res. 2011 Sep;9(9):1242-54. doi: 10.1158/1541-7786.MCR-11-0176. Epub 2011 Jul 20.

15.

Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-{gamma} sumoylation, and HIF-1{alpha}.

Gibbings S, Elkins ND, Fitzgerald H, Tiao J, Weyman ME, Shibao G, Fini MA, Wright RM.

J Biol Chem. 2011 Jan 14;286(2):961-75. doi: 10.1074/jbc.M110.150847. Epub 2010 Nov 8.

16.

Migratory activity of human breast cancer cells is modulated by differential expression of xanthine oxidoreductase.

Fini MA, Orchard-Webb D, Kosmider B, Amon JD, Kelland R, Shibao G, Wright RM.

J Cell Biochem. 2008 Nov 1;105(4):1008-26. doi: 10.1002/jcb.21901.

17.

Alpha-4/beta-1 and alpha-L/beta-2 integrins mediate cytokine induced lung leukocyte-epithelial adhesion and injury.

Parmley LA, Elkins ND, Fini MA, Liu YE, Repine JE, Wright RM.

Br J Pharmacol. 2007 Nov;152(6):915-29. Epub 2007 Sep 10.

18.
19.

Stress activation of mammary epithelial cell xanthine oxidoreductase is mediated by p38 MAPK and CCAAT/enhancer-binding protein-beta.

Seymour KJ, Roberts LE, Fini MA, Parmley LA, Oustitch TL, Wright RM.

J Biol Chem. 2006 Mar 31;281(13):8545-58. Epub 2006 Feb 1.

20.

Aerosol-administered alpha-tocopherol attenuates lung inflammation in rats given lipopolysaccharide intratracheally.

Hybertson BM, Chung JH, Fini MA, Lee YM, Allard JD, Hansen BN, Cho OJ, Shibao GN, Repine JE.

Exp Lung Res. 2005 Apr;31(3):283-94.

PMID:
15962709

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