Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 83

1.

Type I-F CRISPR-Cas resistance against virulent phages results in abortive infection and provides population-level immunity.

Watson BNJ, Vercoe RB, Salmond GPC, Westra ER, Staals RHJ, Fineran PC.

Nat Commun. 2019 Dec 4;10(1):5526. doi: 10.1038/s41467-019-13445-2.

PMID:
31797922
2.

Expanding the mass range for UVPD-based native top-down mass spectrometry.

Greisch JF, Tamara S, Scheltema RA, Maxwell HWR, Fagerlund RD, Fineran PC, Tetter S, Hilvert D, Heck AJR.

Chem Sci. 2019 Jul 1;10(30):7163-7171. doi: 10.1039/c9sc01857c. eCollection 2019 Aug 14.

3.

The autoregulator Aca2 mediates anti-CRISPR repression.

Birkholz N, Fagerlund RD, Smith LM, Jackson SA, Fineran PC.

Nucleic Acids Res. 2019 Oct 10;47(18):9658-9665. doi: 10.1093/nar/gkz721.

4.

Global phylogeography and ancient evolution of the widespread human gut virus crAssphage.

Edwards RA, Vega AA, Norman HM, Ohaeri M, Levi K, Dinsdale EA, Cinek O, Aziz RK, McNair K, Barr JJ, Bibby K, Brouns SJJ, Cazares A, de Jonge PA, Desnues C, Díaz Muñoz SL, Fineran PC, Kurilshikov A, Lavigne R, Mazankova K, McCarthy DT, Nobrega FL, Reyes Muñoz A, Tapia G, Trefault N, Tyakht AV, Vinuesa P, Wagemans J, Zhernakova A, Aarestrup FM, Ahmadov G, Alassaf A, Anton J, Asangba A, Billings EK, Cantu VA, Carlton JM, Cazares D, Cho GS, Condeff T, Cortés P, Cranfield M, Cuevas DA, De la Iglesia R, Decewicz P, Doane MP, Dominy NJ, Dziewit L, Elwasila BM, Eren AM, Franz C, Fu J, Garcia-Aljaro C, Ghedin E, Gulino KM, Haggerty JM, Head SR, Hendriksen RS, Hill C, Hyöty H, Ilina EN, Irwin MT, Jeffries TC, Jofre J, Junge RE, Kelley ST, Khan Mirzaei M, Kowalewski M, Kumaresan D, Leigh SR, Lipson D, Lisitsyna ES, Llagostera M, Maritz JM, Marr LC, McCann A, Molshanski-Mor S, Monteiro S, Moreira-Grez B, Morris M, Mugisha L, Muniesa M, Neve H, Nguyen NP, Nigro OD, Nilsson AS, O'Connell T, Odeh R, Oliver A, Piuri M, Prussin Ii AJ, Qimron U, Quan ZX, Rainetova P, Ramírez-Rojas A, Raya R, Reasor K, Rice GAO, Rossi A, Santos R, Shimashita J, Stachler EN, Stene LC, Strain R, Stumpf R, Torres PJ, Twaddle A, Ugochi Ibekwe M, Villagra N, Wandro S, White B, Whiteley A, Whiteson KL, Wijmenga C, Zambrano MM, Zschach H, Dutilh BE.

Nat Microbiol. 2019 Oct;4(10):1727-1736. doi: 10.1038/s41564-019-0494-6. Epub 2019 Jul 8.

PMID:
31285584
5.

GalK limits type I-F CRISPR-Cas expression in a CRP-dependent manner.

Hampton HG, Patterson AG, Chang JT, Taylor C, Fineran PC.

FEMS Microbiol Lett. 2019 Jun 1;366(11). pii: fnz137. doi: 10.1093/femsle/fnz137.

PMID:
31226710
6.

Bacterial dormancy curbs phage epidemics.

Jackson SA, Fineran PC.

Nature. 2019 Jun;570(7760):173-174. doi: 10.1038/d41586-019-01595-8. No abstract available.

PMID:
31182829
7.

Genome Sequence of a Jumbo Bacteriophage That Infects the Kiwifruit Phytopathogen Pseudomonas syringae pv. actinidiae.

Wojtus JK, Frampton RA, Warring S, Hendrickson H, Fineran PC.

Microbiol Resour Announc. 2019 May 30;8(22). pii: e00224-19. doi: 10.1128/MRA.00224-19.

8.

A Unified Resource for Tracking Anti-CRISPR Names.

Bondy-Denomy J, Davidson AR, Doudna JA, Fineran PC, Maxwell KL, Moineau S, Peng X, Sontheimer EJ, Wiedenheft B.

CRISPR J. 2018 Oct;1:304-305. doi: 10.1089/crispr.2018.0043. No abstract available.

PMID:
31021273
9.

Resistance is not futile: bacterial 'innate' and CRISPR-Cas 'adaptive' immune systems.

Fineran PC.

Microbiology. 2019 Aug;165(8):834-841. doi: 10.1099/mic.0.000802. Epub 2019 Apr 8.

PMID:
30958259
10.

Different genetic and morphological outcomes for phages targeted by single or multiple CRISPR-Cas spacers.

Watson BNJ, Easingwood RA, Tong B, Wolf M, Salmond GPC, Staals RHJ, Bostina M, Fineran PC.

Philos Trans R Soc Lond B Biol Sci. 2019 May 13;374(1772):20180090. doi: 10.1098/rstb.2018.0090.

PMID:
30905290
11.

Genome-wide correlation analysis suggests different roles of CRISPR-Cas systems in the acquisition of antibiotic resistance genes in diverse species.

Shehreen S, Chyou TY, Fineran PC, Brown CM.

Philos Trans R Soc Lond B Biol Sci. 2019 May 13;374(1772):20180384. doi: 10.1098/rstb.2018.0384.

PMID:
30905286
12.

Reconstitution of CRISPR adaptation in vitro and its detection by PCR.

Fagerlund RD, Ferguson TJ, Maxwell HWR, Opel-Reading HK, Krause KL, Fineran PC.

Methods Enzymol. 2019;616:411-433. doi: 10.1016/bs.mie.2018.10.024. Epub 2019 Jan 12.

PMID:
30691653
13.

Imprecise Spacer Acquisition Generates CRISPR-Cas Immune Diversity through Primed Adaptation.

Jackson SA, Birkholz N, Malone LM, Fineran PC.

Cell Host Microbe. 2019 Feb 13;25(2):250-260.e4. doi: 10.1016/j.chom.2018.12.014. Epub 2019 Jan 17.

PMID:
30661951
14.

CRISPR-Cas impedes archaeal mating.

Fineran PC.

Nat Microbiol. 2019 Jan;4(1):2-3. doi: 10.1038/s41564-018-0326-0. No abstract available.

PMID:
30546095
15.

Phage-based biocontrol strategies and their application in agriculture and aquaculture.

Dy RL, Rigano LA, Fineran PC.

Biochem Soc Trans. 2018 Dec 17;46(6):1605-1613. doi: 10.1042/BST20180178. Epub 2018 Dec 4. Review.

PMID:
30514766
16.

Bioinformatic evidence of widespread priming in type I and II CRISPR-Cas systems.

Nicholson TJ, Jackson SA, Croft BI, Staals RHJ, Fineran PC, Brown CM.

RNA Biol. 2019 Apr;16(4):566-576. doi: 10.1080/15476286.2018.1509662. Epub 2018 Sep 18.

17.

Correction: Type III CRISPR-Cas systems can provide redundancy to counteract viral escape from type I systems.

Silas S, Lucas-Elio P, Jackson SA, Aroca-Crevillén A, Hansen LL, Fineran PC, Fire AZ, Sánchez-Amat A.

Elife. 2018 Apr 4;7. pii: e36853. doi: 10.7554/eLife.36853. No abstract available.

18.

AbiEi Binds Cooperatively to the Type IV abiE Toxin-Antitoxin Operator Via a Positively-Charged Surface and Causes DNA Bending and Negative Autoregulation.

Hampton HG, Jackson SA, Fagerlund RD, Vogel AIM, Dy RL, Blower TR, Fineran PC.

J Mol Biol. 2018 Apr 13;430(8):1141-1156. doi: 10.1016/j.jmb.2018.02.022. Epub 2018 Mar 6.

PMID:
29518409
19.

CRISPR-Cas-Mediated Phage Resistance Enhances Horizontal Gene Transfer by Transduction.

Watson BNJ, Staals RHJ, Fineran PC.

MBio. 2018 Feb 13;9(1). pii: e02406-17. doi: 10.1128/mBio.02406-17.

20.

Type III CRISPR-Cas systems can provide redundancy to counteract viral escape from type I systems.

Silas S, Lucas-Elio P, Jackson SA, Aroca-Crevillén A, Hansen LL, Fineran PC, Fire AZ, Sánchez-Amat A.

Elife. 2017 Aug 17;6. pii: e27601. doi: 10.7554/eLife.27601. Erratum in: Elife. 2018 Apr 04;7:.

21.

Spacer capture and integration by a type I-F Cas1-Cas2-3 CRISPR adaptation complex.

Fagerlund RD, Wilkinson ME, Klykov O, Barendregt A, Pearce FG, Kieper SN, Maxwell HWR, Capolupo A, Heck AJR, Krause KL, Bostina M, Scheltema RA, Staals RHJ, Fineran PC.

Proc Natl Acad Sci U S A. 2017 Jun 27;114(26):E5122-E5128. doi: 10.1073/pnas.1618421114. Epub 2017 Jun 13.

22.

CRISPR-Cas: Adapting to change.

Jackson SA, McKenzie RE, Fagerlund RD, Kieper SN, Fineran PC, Brouns SJ.

Science. 2017 Apr 7;356(6333). pii: eaal5056. doi: 10.1126/science.aal5056. Epub 2017 Apr 6. Review.

PMID:
28385959
23.

Regulation of CRISPR-Cas adaptive immune systems.

Patterson AG, Yevstigneyeva MS, Fineran PC.

Curr Opin Microbiol. 2017 Jun;37:1-7. doi: 10.1016/j.mib.2017.02.004. Epub 2017 Mar 27. Review.

PMID:
28359988
24.

Transposon insertion libraries for the characterization of mutants from the kiwifruit pathogen Pseudomonas syringae pv. actinidiae.

Mesarich CH, Rees-George J, Gardner PP, Ghomi FA, Gerth ML, Andersen MT, Rikkerink EH, Fineran PC, Templeton MD.

PLoS One. 2017 Mar 1;12(3):e0172790. doi: 10.1371/journal.pone.0172790. eCollection 2017.

25.

Evolution of Pectobacterium Bacteriophage ΦM1 To Escape Two Bifunctional Type III Toxin-Antitoxin and Abortive Infection Systems through Mutations in a Single Viral Gene.

Blower TR, Chai R, Przybilski R, Chindhy S, Fang X, Kidman SE, Tan H, Luisi BF, Fineran PC, Salmond GPC.

Appl Environ Microbiol. 2017 Mar 31;83(8). pii: e03229-16. doi: 10.1128/AEM.03229-16. Print 2017 Apr 15.

26.

Quorum Sensing Controls Adaptive Immunity through the Regulation of Multiple CRISPR-Cas Systems.

Patterson AG, Jackson SA, Taylor C, Evans GB, Salmond GPC, Przybilski R, Staals RHJ, Fineran PC.

Mol Cell. 2016 Dec 15;64(6):1102-1108. doi: 10.1016/j.molcel.2016.11.012. Epub 2016 Nov 17.

27.

Interference-driven spacer acquisition is dominant over naive and primed adaptation in a native CRISPR-Cas system.

Staals RH, Jackson SA, Biswas A, Brouns SJ, Brown CM, Fineran PC.

Nat Commun. 2016 Oct 3;7:12853. doi: 10.1038/ncomms12853.

28.

Inactivation of CRISPR-Cas systems by anti-CRISPR proteins in diverse bacterial species.

Pawluk A, Staals RH, Taylor C, Watson BN, Saha S, Fineran PC, Maxwell KL, Davidson AR.

Nat Microbiol. 2016 Jun 13;1(8):16085. doi: 10.1038/nmicrobiol.2016.85.

PMID:
27573108
29.

CRISPRDetect: A flexible algorithm to define CRISPR arrays.

Biswas A, Staals RH, Morales SE, Fineran PC, Brown CM.

BMC Genomics. 2016 May 17;17:356. doi: 10.1186/s12864-016-2627-0.

30.

Pectobacterium atrosepticum and Pectobacterium carotovorum Harbor Distinct, Independently Acquired Integrative and Conjugative Elements Encoding Coronafacic Acid that Enhance Virulence on Potato Stems.

Panda P, Vanga BR, Lu A, Fiers M, Fineran PC, Butler R, Armstrong K, Ronson CW, Pitman AR.

Front Microbiol. 2016 Mar 31;7:397. doi: 10.3389/fmicb.2016.00397. eCollection 2016.

31.

CRISPR-Cas gene-editing reveals RsmA and RsmC act through FlhDC to repress the SdhE flavinylation factor and control motility and prodigiosin production in Serratia.

Hampton HG, McNeil MB, Paterson TJ, Ney B, Williamson NR, Easingwood RA, Bostina M, Salmond GPC, Fineran PC.

Microbiology. 2016 Jun;162(6):1047-1058. doi: 10.1099/mic.0.000283. Epub 2016 Mar 24.

32.

Structural plasticity and in vivo activity of Cas1 from the type I-F CRISPR-Cas system.

Wilkinson ME, Nakatani Y, Staals RH, Kieper SN, Opel-Reading HK, McKenzie RE, Fineran PC, Krause KL.

Biochem J. 2016 Apr 15;473(8):1063-72. doi: 10.1042/BCJ20160078. Epub 2016 Feb 29.

PMID:
26929403
33.

The Cpf1 CRISPR-Cas protein expands genome-editing tools.

Fagerlund RD, Staals RH, Fineran PC.

Genome Biol. 2015 Nov 17;16:251. doi: 10.1186/s13059-015-0824-9.

34.

A century of the phage: past, present and future.

Salmond GP, Fineran PC.

Nat Rev Microbiol. 2015 Dec;13(12):777-86. doi: 10.1038/nrmicro3564. Epub 2015 Nov 9. Review.

PMID:
26548913
35.

Complete DNA Sequence of Pseudomonas syringae pv. actinidiae, the Causal Agent of Kiwifruit Canker Disease.

Templeton MD, Warren BA, Andersen MT, Rikkerink EH, Fineran PC.

Genome Announc. 2015 Sep 17;3(5). pii: e01054-15. doi: 10.1128/genomeA.01054-15.

36.

Phage ΦPan70, a Putative Temperate Phage, Controls Pseudomonas aeruginosa in Planktonic, Biofilm and Burn Mouse Model Assays.

Holguín AV, Rangel G, Clavijo V, Prada C, Mantilla M, Gomez MC, Kutter E, Taylor C, Fineran PC, Barrios AF, Vives MJ.

Viruses. 2015 Aug 12;7(8):4602-23. doi: 10.3390/v7082835.

37.

Genome, Proteome and Structure of a T7-Like Bacteriophage of the Kiwifruit Canker Phytopathogen Pseudomonas syringae pv. actinidiae.

Frampton RA, Acedo EL, Young VL, Chen D, Tong B, Taylor C, Easingwood RA, Pitman AR, Kleffmann T, Bostina M, Fineran PC.

Viruses. 2015 Jun 24;7(7):3361-79. doi: 10.3390/v7072776.

38.

Regulation of the Type I-F CRISPR-Cas system by CRP-cAMP and GalM controls spacer acquisition and interference.

Patterson AG, Chang JT, Taylor C, Fineran PC.

Nucleic Acids Res. 2015 Jul 13;43(12):6038-48. doi: 10.1093/nar/gkv517. Epub 2015 May 24.

39.

Computational Detection of CRISPR/crRNA Targets.

Biswas A, Fineran PC, Brown CM.

Methods Mol Biol. 2015;1311:77-89. doi: 10.1007/978-1-4939-2687-9_5.

PMID:
25981467
40.

Remarkable Mechanisms in Microbes to Resist Phage Infections.

Dy RL, Richter C, Salmond GP, Fineran PC.

Annu Rev Virol. 2014 Nov;1(1):307-31. doi: 10.1146/annurev-virology-031413-085500. Epub 2014 Jun 27.

PMID:
26958724
41.

Priming in the Type I-F CRISPR-Cas system triggers strand-independent spacer acquisition, bi-directionally from the primed protospacer.

Richter C, Dy RL, McKenzie RE, Watson BN, Taylor C, Chang JT, McNeil MB, Staals RH, Fineran PC.

Nucleic Acids Res. 2014 Jul;42(13):8516-26. doi: 10.1093/nar/gku527. Epub 2014 Jul 2.

42.

Degenerate target sites mediate rapid primed CRISPR adaptation.

Fineran PC, Gerritzen MJ, Suárez-Diez M, Künne T, Boekhorst J, van Hijum SA, Staals RH, Brouns SJ.

Proc Natl Acad Sci U S A. 2014 Apr 22;111(16):E1629-38. doi: 10.1073/pnas.1400071111. Epub 2014 Apr 7.

43.

CRISPR-Cas systems: beyond adaptive immunity.

Westra ER, Buckling A, Fineran PC.

Nat Rev Microbiol. 2014 May;12(5):317-26. doi: 10.1038/nrmicro3241. Epub 2014 Apr 7. Review.

PMID:
24704746
44.

Gene regulation by engineered CRISPR-Cas systems.

Fineran PC, Dy RL.

Curr Opin Microbiol. 2014 Apr;18:83-9. doi: 10.1016/j.mib.2014.02.007. Epub 2014 Mar 15. Review.

PMID:
24637219
45.

Accurate computational prediction of the transcribed strand of CRISPR non-coding RNAs.

Biswas A, Fineran PC, Brown CM.

Bioinformatics. 2014 Jul 1;30(13):1805-13. doi: 10.1093/bioinformatics/btu114. Epub 2014 Feb 27.

PMID:
24578404
46.

Identification of bacteriophages for biocontrol of the kiwifruit canker phytopathogen Pseudomonas syringae pv. actinidiae.

Frampton RA, Taylor C, Holguín Moreno AV, Visnovsky SB, Petty NK, Pitman AR, Fineran PC.

Appl Environ Microbiol. 2014 Apr;80(7):2216-28. doi: 10.1128/AEM.00062-14. Epub 2014 Jan 31.

47.

A widespread bacteriophage abortive infection system functions through a Type IV toxin-antitoxin mechanism.

Dy RL, Przybilski R, Semeijn K, Salmond GP, Fineran PC.

Nucleic Acids Res. 2014 Apr;42(7):4590-605. doi: 10.1093/nar/gkt1419. Epub 2014 Jan 24.

48.

The succinate dehydrogenase assembly factor, SdhE, is required for the flavinylation and activation of fumarate reductase in bacteria.

McNeil MB, Hampton HG, Hards KJ, Watson BN, Cook GM, Fineran PC.

FEBS Lett. 2014 Jan 31;588(3):414-21. doi: 10.1016/j.febslet.2013.12.019. Epub 2013 Dec 25.

49.

Draft Genome Sequence of Serratia sp. Strain ATCC 39006, a Model Bacterium for Analysis of the Biosynthesis and Regulation of Prodigiosin, a Carbapenem, and Gas Vesicles.

Fineran PC, Iglesias Cans MC, Ramsay JP, Wilf NM, Cossyleon D, McNeil MB, Williamson NR, Monson RE, Becher SA, Stanton JA, Brügger K, Brown SD, Salmond GP.

Genome Announc. 2013 Dec 12;1(6). pii: e01039-13. doi: 10.1128/genomeA.01039-13.

50.

The subtype I-F CRISPR-Cas system influences pathogenicity island retention in Pectobacterium atrosepticum via crRNA generation and Csy complex formation.

Richter C, Fineran PC.

Biochem Soc Trans. 2013 Dec;41(6):1468-74. doi: 10.1042/BST20130151. Review.

PMID:
24256239

Supplemental Content

Loading ...
Support Center