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Items: 1 to 50 of 74

1.

ISR: background, evolution and implementation, with specific consideration for ligand-binding assays.

Findlay JW, Kelley MM.

Bioanalysis. 2014 Feb;6(3):393-402. doi: 10.4155/bio.13.339. Review.

PMID:
24471958
2.

Specificity of bioanalytical methods for pharmacokinetic support of biological macromolecular therapeutics is important.

Findlay JW.

Bioanalysis. 2011 Mar;3(6):567-9. doi: 10.4155/bio.11.12. No abstract available.

3.

Some important considerations for validation of ligand-binding assays.

Findlay JW.

J Chromatogr B Analyt Technol Biomed Life Sci. 2009 Aug 1;877(23):2191-7. doi: 10.1016/j.jchromb.2008.10.045. Epub 2008 Nov 6. Review.

PMID:
19022709
4.

Specificity and accuracy data for ligand-binding assays for macromolecules should be interpreted with caution.

Findlay JW.

AAPS J. 2008 Sep;10(3):433-4. doi: 10.1208/s12248-008-9047-2. Epub 2008 Jul 17. No abstract available.

5.

Appropriate calibration curve fitting in ligand binding assays.

Findlay JW, Dillard RF.

AAPS J. 2007 Jun 29;9(2):E260-7.

6.

Bioanalytical method validation for macromolecules in support of pharmacokinetic studies.

Smolec J, DeSilva B, Smith W, Weiner R, Kelly M, Lee B, Khan M, Tacey R, Hill H, Celniker A, Shah V, Bowsher R, Mire-Sluis A, Findlay JW, Saltarelli M, Quarmby V, Lansky D, Dillard R, Ullmann M, Keller S, Karnes HT.

Pharm Res. 2005 Sep;22(9):1425-31. Epub 2005 Aug 24. Review.

PMID:
16132353
7.

Pharmacokinetics and tissue distribution of the nonadecapeptide Moli1901 in rats and mice.

McNulty MJ, Hutabarat RH, Findlay JW, Devereux K, Knick VC, Harvey RJ, Molina L.

Xenobiotica. 2003 Feb;33(2):197-210.

PMID:
12623761
8.

Disposition of a specific cyclooxygenase-2 inhibitor, valdecoxib, in human.

Yuan JJ, Yang DC, Zhang JY, Bible R Jr, Karim A, Findlay JW.

Drug Metab Dispos. 2002 Sep;30(9):1013-21.

PMID:
12167567
9.

Bioanalytical method validation--a revisit with a decade of progress.

Shah VP, Midha KK, Findlay JW, Hill HM, Hulse JD, McGilveray IJ, McKay G, Miller KJ, Patnaik RN, Powell ML, Tonelli A, Viswanathan CT, Yacobi A.

Pharm Res. 2000 Dec;17(12):1551-7. No abstract available.

PMID:
11303967
10.

Comparison of celecoxib metabolism and excretion in mouse, rabbit, dog, cynomolgus monkey and rhesus monkey.

Paulson SK, Zhang JY, Jessen SM, Lawal Y, Liu NW, Dudkowski CM, Wang YF, Chang M, Yang D, Findlay JW, Berge MA, Markos CS, Breau AP, Hribar JD, Yuan J.

Xenobiotica. 2000 Jul;30(7):731-44.

PMID:
10963063
11.

Validation of immunoassays for bioanalysis: a pharmaceutical industry perspective.

Findlay JW, Smith WC, Lee JW, Nordblom GD, Das I, DeSilva BS, Khan MN, Bowsher RR.

J Pharm Biomed Anal. 2000 Jan;21(6):1249-73.

PMID:
10708409
13.

Balance/excretion of 3H- and 14C-tyloxapol in the male rabbit after intratracheal administration.

DeAngelis RL, Kearney MF, Barnes ER, Shockcor JP, Findlay JW.

Xenobiotica. 1995 May;25(5):521-30.

PMID:
7571725
14.

Codeine toxicokinetics in rats during a two-year dosed feed study.

Yuan J, Dunnick JK, Barnes ER, Findlay JW.

Drug Metab Dispos. 1994 Jan-Feb;22(1):14-20.

PMID:
8149873
15.

A phase II study of vinblastine in combination with acrivastine in patients with advanced renal cell carcinoma.

Berlin J, King AC, Tutsch K, Findlay JW, Kohler P, Collier M, Clendeninn NJ, Wilding G.

Invest New Drugs. 1994;12(2):137-41.

PMID:
7860231
16.

Metabolism of synthetic surfactants.

DeAngelis RL, Findlay JW.

Clin Perinatol. 1993 Dec;20(4):697-710. Review.

PMID:
8131363
17.

Disposition of digoxin immune Fab in patients with kidney failure.

Ujhelyi MR, Robert S, Cummings DM, Colucci RD, Sailstad JM, Vlasses PH, Findlay JW, Zarowitz BJ.

Clin Pharmacol Ther. 1993 Oct;54(4):388-94.

PMID:
8222481
18.

Radioimmunoassay for the chemical stable prostacyclin analog, 15AU81: a preliminary pharmacokinetics study in the dog.

Findlay JW, McNulty MJ, Page TL, Chang SY, Sailstad JM.

Prostaglandins Leukot Essent Fatty Acids. 1993 Feb;48(2):167-74.

PMID:
8446655
19.

Disposition of triprolidine in the male beagle dog.

McNulty MJ, Deal DL, Page TL, Chandrasurin P, Findlay JW.

Drug Metab Dispos. 1992 Nov-Dec;20(6):928-35.

PMID:
1362948
20.

Disposition and metabolism of triprolidine in mice.

Deal DL, Chandrasurin P, Shockcor J, Minick DJ, Findlay JW, McNulty MJ.

Drug Metab Dispos. 1992 Nov-Dec;20(6):920-7.

PMID:
1362947
21.

Disposition of acrivastine in the male beagle dog.

McNulty MJ, Deal DL, Nelson FR, Weller S, Chandrasurin P, Shockcor J, Findlay JW.

Drug Metab Dispos. 1992 Sep-Oct;20(5):679-87.

PMID:
1358572
22.

Clinical and pharmacokinetic profiles of digoxin immune Fab in four patients with renal impairment.

Allen NM, Dunham GD, Sailstad JM, Findlay JW.

DICP. 1991 Dec;25(12):1315-20.

PMID:
1815424
23.

Immunofluorometric assay for lamotrigine (Lamictal) in human plasma.

Sailstad JM, Findlay JW.

Ther Drug Monit. 1991 Sep;13(5):433-42.

PMID:
1957337
24.

Pharmacokinetics of oral and transdermal triprolidine.

Miles MV, Balasubramanian R, Pittman AW, Grossman SH, Pappa KA, Smith MF, Wargin WA, Findlay JW, Poust RI, Frosolono MF.

J Clin Pharmacol. 1990 Jun;30(6):572-5.

PMID:
2355108
25.

Treatment of digoxin intoxication in a renal failure patient with digoxin-specific antibody fragments and plasmapheresis.

Rabetoy GM, Price CA, Findlay JW, Sailstad JM.

Am J Nephrol. 1990;10(6):518-21.

PMID:
2075910
26.

Quantitative gas chromatographic-mass spectrometric analysis of acrivastine and a metabolite in human plasma.

Chang SY, Nelson FR, Findlay JW, Taylor LC.

J Chromatogr. 1989 Dec 29;497:288-95. No abstract available.

PMID:
2576270
27.

Pharmacokinetics of acrivastine after oral and colonic administration.

Balasubramanian R, Klein KB, Pittman AW, Liao SH, Findlay JW, Frosolono MF.

J Clin Pharmacol. 1989 May;29(5):444-7.

PMID:
2567739
28.

Pholcodine.

Findlay JW.

J Clin Pharm Ther. 1988 Feb;13(1):5-17. Review.

PMID:
3283158
29.

Pharmacokinetics and pharmacodynamics of codeine in end-stage renal disease.

Guay DR, Awni WM, Findlay JW, Halstenson CE, Abraham PA, Opsahl JA, Jones EC, Matzke GR.

Clin Pharmacol Ther. 1988 Jan;43(1):63-71.

PMID:
3335120
30.

Pharmacokinetics of codeine after single- and multiple-oral-dose administration to normal volunteers.

Guay DR, Awni WM, Halstenson CE, Findlay JW, Opsahl JA, Abraham PA, Jones EC, Matzke GR.

J Clin Pharmacol. 1987 Dec;27(12):983-7.

PMID:
3437070
31.

Applications of immunoassay methods to drug disposition studies.

Findlay JW.

Drug Metab Rev. 1987;18(1):83-129. Review. No abstract available.

PMID:
3311685
32.

Pharmacokinetics of intravenous, intrathecal and epidural morphine and fentanyl in the goat.

Andersen HB, Christensen B, Findlay JW, Jansen JA.

Acta Anaesthesiol Scand. 1986 Jul;30(5):393-9.

PMID:
3766095
33.

Comparative disposition of codeine and pholcodine in man after single oral doses.

Findlay JW, Fowle AS, Butz RF, Jones EC, Weatherley BC, Welch RM, Posner J.

Br J Clin Pharmacol. 1986 Jul;22(1):61-71.

34.

Pharmacodynamic and pharmacokinetics of BW 825C: a new antihistamine.

Cohen AF, Hamilton MJ, Liao SH, Findlay JW, Peck AW.

Eur J Clin Pharmacol. 1985;28(2):197-204.

PMID:
2859204
35.

Pseudoephedrine and triprolidine in plasma and breast milk of nursing mothers.

Findlay JW, Butz RF, Sailstad JM, Warren JT, Welch RM.

Br J Clin Pharmacol. 1984 Dec;18(6):901-6.

36.

Bioavailability of pseudoephedrine and triprolidine from combination and single-ingredient products.

Williams BO, Liao SH, Lai AA, Arnold JD, Perkins JG, Blum MR, Findlay JW.

Clin Pharm. 1984 Nov-Dec;3(6):638-43.

PMID:
6509877
37.

Triprolidine radioimmunoassay: disposition in animals and humans.

Findlay JW, Butz RF, Coker GG, DeAngelis RL, Welch RM.

J Pharm Sci. 1984 Oct;73(10):1339-44.

PMID:
6502476
38.

Pharmacokinetics and O-dealkylation of morphine-3-alkyl ethers in the rat. A radioimmunoassay study.

Butz RF, Jones EC, Welch RM, Findlay JW.

Drug Metab Dispos. 1983 Sep-Oct;11(5):481-8.

PMID:
6138235
39.

Biphasic depression of ventilatory responses to CO2 following epidural morphine.

Kafer ER, Brown JT, Scott D, Findlay JW, Butz RF, Teeple E, Ghia JN.

Anesthesiology. 1983 May;58(5):418-27. No abstract available.

PMID:
6220625
40.

Radioimmunoassay for bupropion in human plasma: comparison of tritiated and iodinated radioligands.

Butz RF, Smith PG, Schroeder DH, Findlay JW.

Clin Chem. 1983 Mar;29(3):462-5.

41.

The distribution of some commonly used drugs in human breast milk.

Findlay JW.

Drug Metab Rev. 1983;14(4):653-84. Review. No abstract available.

PMID:
6193936
42.

An evaluation of the effects of smoking on codeine pharmacokinetics and bioavailability in normal human volunteers.

Hull JH, Findlay JW, Rogers JF, Welch RM, Butz RF, Bustrack JA.

Drug Intell Clin Pharm. 1982 Nov;16(11):849-54.

PMID:
7173046
43.

Codeine disposition in smokers and nonsmokers.

Rogers JF, Findlay JW, Hull JH, Butz RF, Jones EC, Bustrack JA, Welch RM.

Clin Pharmacol Ther. 1982 Aug;32(2):218-27.

PMID:
7094509
44.

Plasma levels of a novel antidysrhythmic agent, meobentine sulfate, in humans as determined by radioimmunoassay.

Warren JT, Coker GG, Welch RM, Fowle AS, Findlay JW.

J Pharm Sci. 1982 Jun;71(6):665-70.

PMID:
7097530
45.

Relationship between bupropion disposition and dopamine uptake inhibition in rats and mice.

Butz RF, Welch RM, Findlay JW.

J Pharmacol Exp Ther. 1982 Jun;221(3):676-85. No abstract available.

PMID:
6806465
46.
47.

Morphine in cow and human milk: could dietary morphine constitute a ligand for specific morphine (mu) receptors?

Hazum E, Sabatka JJ, Chang KJ, Brent DA, Findlay JW, Cuatrecasas P.

Science. 1981 Aug 28;213(4511):1010-2.

PMID:
6267691
48.

Stereospecific radioimmunoassays for d-pseudoephedrine in human plasma and their application to bioequivalency studies.

Findlay JW, Warren JT, Hill JA, Welch RM.

J Pharm Sci. 1981 Jun;70(6):624-31.

PMID:
7252804
49.

Radioimmunoassay and pharmacokinetic profile of bupropion in the dog.

Butz RF, Schroeder DH, Welch RM, Mehta NB, Phillips AP, Findlay JW.

J Pharmacol Exp Ther. 1981 Jun;217(3):602-10.

PMID:
6785419
50.

Analgesic drugs in breast milk and plasma.

Findlay JW, DeAngelis RL, Kearney MF, Welch RM, Findlay JM.

Clin Pharmacol Ther. 1981 May;29(5):625-33.

PMID:
7214793

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