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Items: 1 to 50 of 109

1.

Genomic Medicine-Progress, Pitfalls, and Promise.

Shendure J, Findlay GM, Snyder MW.

Cell. 2019 Mar 21;177(1):45-57. doi: 10.1016/j.cell.2019.02.003. Review.

PMID:
30901547
2.

Accurate classification of BRCA1 variants with saturation genome editing.

Findlay GM, Daza RM, Martin B, Zhang MD, Leith AP, Gasperini M, Janizek JD, Huang X, Starita LM, Shendure J.

Nature. 2018 Oct;562(7726):217-222. doi: 10.1038/s41586-018-0461-z. Epub 2018 Sep 12.

3.

RNF12 X-Linked Intellectual Disability Mutations Disrupt E3 Ligase Activity and Neural Differentiation.

Bustos F, Segarra-Fas A, Chaugule VK, Brandenburg L, Branigan E, Toth R, Macartney T, Knebel A, Hay RT, Walden H, Findlay GM.

Cell Rep. 2018 May 8;23(6):1599-1611. doi: 10.1016/j.celrep.2018.04.022.

4.

CRISPR/Cas9-Mediated Scanning for Regulatory Elements Required for HPRT1 Expression via Thousands of Large, Programmed Genomic Deletions.

Gasperini M, Findlay GM, McKenna A, Milbank JH, Lee C, Zhang MD, Cusanovich DA, Shendure J.

Am J Hum Genet. 2017 Aug 3;101(2):192-205. doi: 10.1016/j.ajhg.2017.06.010. Epub 2017 Jul 14.

5.

Brd4-Brd2 isoform switching coordinates pluripotent exit and Smad2-dependent lineage specification.

Fernandez-Alonso R, Davidson L, Hukelmann J, Zengerle M, Prescott AR, Lamond A, Ciulli A, Sapkota GP, Findlay GM.

EMBO Rep. 2017 Jul;18(7):1108-1122. doi: 10.15252/embr.201643534. Epub 2017 Jun 6.

6.
7.

Protein Kinases in Pluripotency-Beyond the Usual Suspects.

Fernandez-Alonso R, Bustos F, Williams CAC, Findlay GM.

J Mol Biol. 2017 May 19;429(10):1504-1520. doi: 10.1016/j.jmb.2017.04.013. Epub 2017 Apr 26. Review.

8.

Molecular Mechanisms of Stem Cell Pluripotency and Cell Fate Specification.

Findlay GM, David L, Beyer TA.

J Mol Biol. 2017 May 19;429(10):1439-1440. doi: 10.1016/j.jmb.2017.03.011. Epub 2017 Mar 14. No abstract available.

PMID:
28302388
9.

Erk5 Is a Key Regulator of Naive-Primed Transition and Embryonic Stem Cell Identity.

Williams CA, Fernandez-Alonso R, Wang J, Toth R, Gray NS, Findlay GM.

Cell Rep. 2016 Aug 16;16(7):1820-8. doi: 10.1016/j.celrep.2016.07.033. Epub 2016 Aug 4.

10.

Whole-organism lineage tracing by combinatorial and cumulative genome editing.

McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J.

Science. 2016 Jul 29;353(6298):aaf7907. doi: 10.1126/science.aaf7907. Epub 2016 May 26.

11.

Systematic dissection of coding exons at single nucleotide resolution supports an additional role in cell-specific transcriptional regulation.

Birnbaum RY, Patwardhan RP, Kim MJ, Findlay GM, Martin B, Zhao J, Bell RJ, Smith RP, Ku AA, Shendure J, Ahituv N.

PLoS Genet. 2014 Oct 23;10(10):e1004592. doi: 10.1371/journal.pgen.1004592. eCollection 2014 Oct.

12.

Genome sequencing of idiopathic pulmonary fibrosis in conjunction with a medical school human anatomy course.

Kumar A, Dougherty M, Findlay GM, Geisheker M, Klein J, Lazar J, Machkovech H, Resnick J, Resnick R, Salter AI, Talebi-Liasi F, Arakawa C, Baudin J, Bogaard A, Salesky R, Zhou Q, Smith K, Clark JI, Shendure J, Horwitz MS.

PLoS One. 2014 Sep 5;9(9):e106744. doi: 10.1371/journal.pone.0106744. eCollection 2014.

13.

Saturation editing of genomic regions by multiplex homology-directed repair.

Findlay GM, Boyle EA, Hause RJ, Klein JC, Shendure J.

Nature. 2014 Sep 4;513(7516):120-3. doi: 10.1038/nature13695.

14.

Directed network wiring identifies a key protein interaction in embryonic stem cell differentiation.

Yasui N, Findlay GM, Gish GD, Hsiung MS, Huang J, Tucholska M, Taylor L, Smith L, Boldridge WC, Koide A, Pawson T, Koide S.

Mol Cell. 2014 Jun 19;54(6):1034-41. doi: 10.1016/j.molcel.2014.05.002. Epub 2014 Jun 5.

15.

A quantitative liposome microarray to systematically characterize protein-lipid interactions.

Saliba AE, Vonkova I, Ceschia S, Findlay GM, Maeda K, Tischer C, Deghou S, van Noort V, Bork P, Pawson T, Ellenberg J, Gavin AC.

Nat Methods. 2014 Jan;11(1):47-50. doi: 10.1038/nmeth.2734. Epub 2013 Nov 24.

PMID:
24270602
16.

An siRNA screen for NFAT activation identifies septins as coordinators of store-operated Ca2+ entry.

Sharma S, Quintana A, Findlay GM, Mettlen M, Baust B, Jain M, Nilsson R, Rao A, Hogan PG.

Nature. 2013 Jul 11;499(7457):238-42. doi: 10.1038/nature12229. Epub 2013 Jun 23.

17.

Interaction domains of Sos1/Grb2 are finely tuned for cooperative control of embryonic stem cell fate.

Findlay GM, Smith MJ, Lanner F, Hsiung MS, Gish GD, Petsalaki E, Cockburn K, Kaneko T, Huang H, Bagshaw RD, Ketela T, Tucholska M, Taylor L, Bowtell DD, Moffat J, Ikura M, Li SS, Sidhu SS, Rossant J, Pawson T.

Cell. 2013 Feb 28;152(5):1008-20. doi: 10.1016/j.cell.2013.01.056.

18.

Dephosphorylation of the nuclear factor of activated T cells (NFAT) transcription factor is regulated by an RNA-protein scaffold complex.

Sharma S, Findlay GM, Bandukwala HS, Oberdoerffer S, Baust B, Li Z, Schmidt V, Hogan PG, Sacks DB, Rao A.

Proc Natl Acad Sci U S A. 2011 Jul 12;108(28):11381-6. doi: 10.1073/pnas.1019711108. Epub 2011 Jun 27. Erratum in: Proc Natl Acad Sci U S A. 2011 Oct 11;108(41):17235.

19.

PP2A T61 epsilon is an inhibitor of MAP4K3 in nutrient signaling to mTOR.

Yan L, Mieulet V, Burgess D, Findlay GM, Sully K, Procter J, Goris J, Janssens V, Morrice NA, Lamb RF.

Mol Cell. 2010 Mar 12;37(5):633-42. doi: 10.1016/j.molcel.2010.01.031.

20.

How is SOS activated? Let us count the ways.

Findlay GM, Pawson T.

Nat Struct Mol Biol. 2008 Jun;15(6):538-40. doi: 10.1038/nsmb0608-538. No abstract available.

PMID:
18523461
21.

A MAP4 kinase related to Ste20 is a nutrient-sensitive regulator of mTOR signalling.

Findlay GM, Yan L, Procter J, Mieulet V, Lamb RF.

Biochem J. 2007 Apr 1;403(1):13-20.

22.

Hyperactivation of mammalian target of rapamycin (mTOR) signaling by a gain-of-function mutant of the Rheb GTPase.

Yan L, Findlay GM, Jones R, Procter J, Cao Y, Lamb RF.

J Biol Chem. 2006 Jul 21;281(29):19793-7. Epub 2006 May 25.

23.

TSC1-2 tumour suppressor and regulation of mTOR signalling: linking cell growth and proliferation?

Findlay GM, Harrington LS, Lamb RF.

Curr Opin Genet Dev. 2005 Feb;15(1):69-76.

PMID:
15661536
24.

Restraining PI3K: mTOR signalling goes back to the membrane.

Harrington LS, Findlay GM, Lamb RF.

Trends Biochem Sci. 2005 Jan;30(1):35-42. Review.

PMID:
15653324
25.

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.

Harrington LS, Findlay GM, Gray A, Tolkacheva T, Wigfield S, Rebholz H, Barnett J, Leslie NR, Cheng S, Shepherd PR, Gout I, Downes CP, Lamb RF.

J Cell Biol. 2004 Jul 19;166(2):213-23. Epub 2004 Jul 12.

26.

Ultra-violet light and skin cancer.

Findlay GM.

CA Cancer J Clin. 1979 May-Jun;29(3):169-71. No abstract available.

27.

Quantitative gas chromatographic analysis of dimethoate and several metabolites in rape, quail, and grasshopper tissues by derivatization.

Sarna LP, Howe GJ, Findlay GM, Webster GR.

J Agric Food Chem. 1976 Sep-Oct;24(5):1046-8. No abstract available.

PMID:
965590
28.

DDT movement from adipocyte to muscle cell during lipid utilization.

Findlay GM, DeFreitas AS.

Nature. 1971 Jan 1;229(5279):63-5. No abstract available.

PMID:
4922794
29.

Metabolism of 1-14C-methyl linoleate hydroperoxide in the rabbit.

Findlay GM, Draper HH, Bergan JG.

Lipids. 1970 Dec;5(12):970-5. No abstract available.

PMID:
5500183
30.

LIVER VITAMIN A STORAGE IN FATTENING CATTLE FOLLOWING INTRARUMINAL OR INTRAMUSCULAR INJECTION OF VITAMIN A.

ROBERTS WK, FINDLAY GM, STRINGAM EW.

Can J Comp Med Vet Sci. 1965 Feb;29:43-5.

31.

The significance of bodies seen in Giemsa-stained urethral scrapings in nonspecific urethritis.

WILLCOX RR, HOWARD EM, FINDLAY GM.

Am J Syph Gonorrhea Vener Dis. 1954 May;38(3):216-36. No abstract available.

PMID:
13158744
32.

Attempts to passage the virus of non-specific urethritis.

WILLCOX RR, HOWARD EM, FINDLAY GM.

Br J Vener Dis. 1954 Mar;30(1):31-5. No abstract available.

33.

Bornholm disease in children.

DISNEY ME, HOWARD EM, WOOD BS, FINDLAY GM.

Br Med J. 1953 Jun 20;1(4824):1351-4. No abstract available.

34.

[Hepatitis and viral infections].

FINDLAY GM.

Dtsch Z Verdau Stoffwechselkr. 1953;9:270-83. Undetermined Language. No abstract available.

PMID:
13150966
35.

Poliomyelitis in relation to intramuscular injections of quinine and other drugs.

TOWNSEND-COLES WF, FINDLAY GM.

Trans R Soc Trop Med Hyg. 1953 Jan;47(1):77-81. No abstract available.

PMID:
13077703
36.

Treatment of tropical ulcer with terramycin ointment.

AMPOFO O, FINDLAY GM.

Trans R Soc Trop Med Hyg. 1952 Nov;46(6):650-2. No abstract available.

PMID:
13005682
37.

Further studies on the treatment of nonspecific urethritis with terramycin.

WILLCOX RR, FINDLAY GM.

Am J Syph Gonorrhea Vener Dis. 1952 Jul;36(4):388-93. No abstract available.

PMID:
14933684
38.

The susceptibility of rats to Rift Valley fever in relation to age.

FINDLAY GM, HOWARD EM.

Ann Trop Med Parasitol. 1952 May;46(1):33-7. No abstract available.

PMID:
14934035
39.

Cortisone and Plasmodium berghei infection in mice.

FINDLAY GM, HOWARD EM.

Nature. 1952 Mar 29;169(4300):547. No abstract available.

PMID:
14929234
40.

Terramycin for nongonococcic urethritis and Reiter's disease.

WILLCOX RR, FINDLAY GM.

Public Health Rep. 1952 Feb;67(2):196-9. No abstract available.

41.

Wilbur A. Swayer 1879-1951.

FINDLAY GM.

Trans R Soc Trop Med Hyg. 1952 Jan;46(1):109-11. No abstract available.

PMID:
14913666
42.

The effects of cortisone and adrenocorticotrophic hormone on poliomyelitis and on the other virus infections.

FINDLAY GM, HOWARD EM.

J Pharm Pharmacol. 1952 Jan;4(1):37-42. No abstract available.

PMID:
14908921
43.

[Hepatitis and viral infections].

FINDLAY GM.

Dtsch Z Verdau Stoffwechselkr. 1952;12(Spec No):271-83. Undetermined Language. No abstract available.

PMID:
12979940
44.

The transmission of neurotropic yellow fever virus to rats.

FINDLAY GM, HOWARD EM.

Ann Trop Med Parasitol. 1951 Dec;45(3-4):220-2. No abstract available.

PMID:
14915460
45.

The susceptibility of rats to encephalomyocarditis viruses.

FINDLAY GM, HOWARD EM.

Br J Exp Pathol. 1951 Dec;32(6):569-72. No abstract available.

46.

The treatment of inclusion urethritis, including one case of Reiter's disease, with chloramphenicol.

FINDLAY GM, WILLCOX RR.

Am J Syph Gonorrhea Vener Dis. 1951 Nov;35(6):583-92. No abstract available.

PMID:
14885629
47.

The treatment of tropical ulcers with aureomycin ointment.

AMPOFO O, FINDLAY GM.

Trans R Soc Trop Med Hyg. 1951 Oct;45(2):265-7. No abstract available.

PMID:
14893444
48.

Terramycin in the treatment of yaws and tropical ulcer.

AMPOFO O, FINDLAY GM.

Trans R Soc Trop Med Hyg. 1951 Oct;45(2):261-3. No abstract available.

PMID:
14893443
49.

The virus and the cell.

FINDLAY GM.

J R Microsc Soc. 1951 Sep;71(2):151-75. No abstract available.

PMID:
14909179
50.

Observations on Columbia SK virus.

FINDLAY GM, HOWARD EM.

J Pathol Bacteriol. 1951 Jul;63(3):435-43. No abstract available.

PMID:
14874158

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