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Lung Dendritic Cells Drive NK Cytotoxicity in Chronic Obstructive Pulmonary Disease via IL-15Rα.

Finch DK, Stolberg VR, Ferguson J, Alikaj H, Kady MR, Richmond BW, Polosukhin VV, Blackwell TS, McCloskey L, Curtis JL, Freeman CM.

Am J Respir Crit Care Med. 2018 Apr 20. doi: 10.1164/rccm.201712-2513OC. [Epub ahead of print]


360° virtual reality video for the acquisition of knot tying skills: A randomised controlled trial.

Yoganathan S, Finch DA, Parkin E, Pollard J.

Int J Surg. 2018 Jun;54(Pt A):24-27. doi: 10.1016/j.ijsu.2018.04.002. Epub 2018 Apr 10.


A prognostic model for stratifying clinical outcomes in chemotherapy-naive metastatic castration-resistant prostate cancer patients treated with abiraterone acetate.

Khalaf DJ, Avilés CM, Azad AA, Sunderland K, Todenhöfer T, Eigl BJ, Finch D, Le L, Atwell A, Keith B, Kollmannsberger C, Chi KN.

Can Urol Assoc J. 2018 Feb;12(2):E47-E52. doi: 10.5489/cuaj.4600. Epub 2017 Dec 1.


Circulating Tumor DNA Genomics Correlate with Resistance to Abiraterone and Enzalutamide in Prostate Cancer.

Annala M, Vandekerkhove G, Khalaf D, Taavitsainen S, Beja K, Warner EW, Sunderland K, Kollmannsberger C, Eigl BJ, Finch D, Oja CD, Vergidis J, Zulfiqar M, Azad AA, Nykter M, Gleave ME, Wyatt AW, Chi KN.

Cancer Discov. 2018 Apr;8(4):444-457. doi: 10.1158/2159-8290.CD-17-0937. Epub 2018 Jan 24.


Classifying Clinical Notes with Pain Assessment.

Fodeh SJ, Finch D, Bouayad L, Luther S, Kerns RD, Brandt C.

Stud Health Technol Inform. 2017;245:1261.


Classifying clinical notes with pain assessment using machine learning.

Fodeh SJ, Finch D, Bouayad L, Luther SL, Ling H, Kerns RD, Brandt C.

Med Biol Eng Comput. 2018 Jul;56(7):1285-1292. doi: 10.1007/s11517-017-1772-1. Epub 2017 Dec 26.


Tragedy of the commons in the chemostat.

Schuster M, Foxall E, Finch D, Smith H, De Leenheer P.

PLoS One. 2017 Dec 20;12(12):e0186119. doi: 10.1371/journal.pone.0186119. eCollection 2017.


Metabolic re-patterning in COPD airway smooth muscle cells.

Michaeloudes C, Kuo CH, Haji G, Finch DK, Halayko AJ, Kirkham P, Chung KF, Adcock IM; COPDMAP.

Eur Respir J. 2017 Nov 30;50(5). pii: 1700202. doi: 10.1183/13993003.00202-2017. Print 2017 Nov.


Characterisation of mineral deposition systems associated with rock art in the Kimberley region of northwest Australia.

Green H, Gleadow A, Finch D.

Data Brief. 2017 Sep 7;14:813-835. doi: 10.1016/j.dib.2017.08.029. eCollection 2017 Oct.


IL-18 associated with lung lymphoid aggregates drives IFNγ production in severe COPD.

Briend E, Ferguson GJ, Mori M, Damera G, Stephenson K, Karp NA, Sethi S, Ward CK, Sleeman MA, Erjefält JS, Finch DK.

Respir Res. 2017 Aug 22;18(1):159. doi: 10.1186/s12931-017-0641-7.


A randomised, placebo-controlled trial of anti-interleukin-1 receptor 1 monoclonal antibody MEDI8968 in chronic obstructive pulmonary disease.

Calverley PMA, Sethi S, Dawson M, Ward CK, Finch DK, Penney M, Newbold P, van der Merwe R.

Respir Res. 2017 Aug 9;18(1):153. doi: 10.1186/s12931-017-0633-7.


Revalidation fosters a culture of reflection and good practice.

Finch DJ.

Nurs Stand. 2017 Aug 2;31(49):30. doi: 10.7748/ns.31.49.30.s26.


Leveraging Electronic Health Care Record Information to Measure Pressure Ulcer Risk in Veterans With Spinal Cord Injury: A Longitudinal Study Protocol.

Luther SL, Thomason SS, Sabharwal S, Finch DK, McCart J, Toyinbo P, Bouayad L, Matheny ME, Gobbel GT, Powell-Cope G.

JMIR Res Protoc. 2017 Jan 19;6(1):e3. doi: 10.2196/resprot.5948.


This new year could match 2016 for exciting nursing developments.

Finch DJ.

Nurs Stand. 2017 Jan 18;31(21):28. doi: 10.7748/ns.31.21.28.s27.


Shaping the future of regulation.

Finch DJ.

Nurs Stand. 2016 Sep 28;31(5):28. doi: 10.7748/ns.31.5.28.s26.


Degree-level education is an essential part of modern health care.

Finch DJ.

Nurs Stand. 2016 Aug 17;30(51):28. doi: 10.7748/ns.30.51.28.s26.


The NMC has to look beyond England, says Janet Finch.

Finch DJ.

Nurs Stand. 2016 Jun 29;30(44):28. doi: 10.7748/ns.30.44.28.s27.


Voices - Finally, proof revalidation is not the nightmare many feared, says Janet Finch.

Finch DJ.

Nurs Stand. 2016 May 18;30(38):26. doi: 10.7748/ns.30.38.26.s24.


Development of therapeutic antibodies to G protein-coupled receptors and ion channels: Opportunities, challenges and their therapeutic potential in respiratory diseases.

Douthwaite JA, Finch DK, Mustelin T, Wilkinson TC.

Pharmacol Ther. 2017 Jan;169:113-123. doi: 10.1016/j.pharmthera.2016.04.013. Epub 2016 May 3. Review.


Implications of Climate Change for Bird Conservation in the Southwestern U.S. under Three Alternative Futures.

Friggens MM, Finch DM.

PLoS One. 2015 Dec 23;10(12):e0144089. doi: 10.1371/journal.pone.0144089. eCollection 2015.


Effects of Kettlebell Training on Aerobic Capacity.

Falatic JA, Plato PA, Holder C, Finch D, Han K, Cisar CJ.

J Strength Cond Res. 2015 Jul;29(7):1943-7. doi: 10.1519/JSC.0000000000000845.


A phase II study of the HDAC inhibitor SB939 in patients with castration resistant prostate cancer: NCIC clinical trials group study IND195.

Eigl BJ, North S, Winquist E, Finch D, Wood L, Sridhar SS, Powers J, Good J, Sharma M, Squire JA, Bazov J, Jamaspishvili T, Cox ME, Bradbury PA, Eisenhauer EA, Chi KN.

Invest New Drugs. 2015 Aug;33(4):969-76. doi: 10.1007/s10637-015-0252-4. Epub 2015 May 19.


Improving identification of fall-related injuries in ambulatory care using statistical text mining.

Luther SL, McCart JA, Berndt DJ, Hahm B, Finch D, Jarman J, Foulis PR, Lapcevic WA, Campbell RR, Shorr RI, Valencia KM, Powell-Cope G.

Am J Public Health. 2015 Jun;105(6):1168-73. doi: 10.2105/AJPH.2014.302440. Epub 2015 Apr 16.


Voices - Like nurses, education must adapt to changes in care, says Janet Finch.

Finch DJ.

Nurs Stand. 2015 Mar 18;29(29):26. doi: 10.7748/ns.29.29.26.s24.


Finding a place for interleukin-1 inhibitors in the treatment of rheumatologic diseases.

Finch D, Sleeman M.

Curr Pharm Des. 2015;21(17):2198-205. Review.


Safety of supervised trainee-performed laparoscopic surgery for inflammatory bowel disease.

Celentano V, Finch D, Forster L, Robinson JM, Griffith JP.

Int J Colorectal Dis. 2015 May;30(5):639-44. doi: 10.1007/s00384-015-2147-4. Epub 2015 Feb 12.


Using information from the electronic health record to improve measurement of unemployment in service members and veterans with mTBI and post-deployment stress.

Dillahunt-Aspillaga C, Finch D, Massengale J, Kretzmer T, Luther SL, McCart JA.

PLoS One. 2014 Dec 26;9(12):e115873. doi: 10.1371/journal.pone.0115873. eCollection 2014.


Affinity maturation of a novel antagonistic human monoclonal antibody with a long VH CDR3 targeting the Class A GPCR formyl-peptide receptor 1.

Douthwaite JA, Sridharan S, Huntington C, Hammersley J, Marwood R, Hakulinen JK, Ek M, Sjögren T, Rider D, Privezentzev C, Seaman JC, Cariuk P, Knights V, Young J, Wilkinson T, Sleeman M, Finch DK, Lowe DC, Vaughan TJ.

MAbs. 2015;7(1):152-66. doi: 10.4161/19420862.2014.985158.


Final report of a phase 2 clinical trial of lenalidomide monotherapy for patients with T-cell lymphoma.

Toumishey E, Prasad A, Dueck G, Chua N, Finch D, Johnston J, van der Jagt R, Stewart D, White D, Belch A, Reiman T.

Cancer. 2015 Mar 1;121(5):716-23. doi: 10.1002/cncr.29103. Epub 2014 Oct 29.


TagLine: Information Extraction for Semi-Structured Text in Medical Progress Notes.

Finch DK, McCart JA, Luther SL.

AMIA Annu Symp Proc. 2014 Nov 14;2014:534-43. eCollection 2014.


The role of interleukin-1 and interleukin-18 in pro-inflammatory and anti-viral responses to rhinovirus in primary bronchial epithelial cells.

Piper SC, Ferguson J, Kay L, Parker LC, Sabroe I, Sleeman MA, Briend E, Finch DK.

PLoS One. 2013 May 28;8(5):e63365. doi: 10.1371/journal.pone.0063365. Print 2013.


Rituximab causes a polarization of B cells that augments its therapeutic function in NK-cell-mediated antibody-dependent cellular cytotoxicity.

Rudnicka D, Oszmiana A, Finch DK, Strickland I, Schofield DJ, Lowe DC, Sleeman MA, Davis DM.

Blood. 2013 Jun 6;121(23):4694-702. doi: 10.1182/blood-2013-02-482570. Epub 2013 Apr 23.


Effects of CXCL13 inhibition on lymphoid follicles in models of autoimmune disease.

Finch DK, Ettinger R, Karnell JL, Herbst R, Sleeman MA.

Eur J Clin Invest. 2013 May;43(5):501-9. doi: 10.1111/eci.12063. Epub 2013 Mar 20. Review.


Finding falls in ambulatory care clinical documents using statistical text mining.

McCart JA, Berndt DJ, Jarman J, Finch DK, Luther SL.

J Am Med Inform Assoc. 2013 Sep-Oct;20(5):906-14. doi: 10.1136/amiajnl-2012-001334. Epub 2012 Dec 15.


Successful Management of Jejunal Perforation in Burkitt's Lymphoma: A Case Report.

Finch DA, Wilson MS, O'Dwyer ST.

Case Rep Surg. 2012;2012:230538. Epub 2012 Sep 17.


Cigarette smoke-induced accumulation of lung dendritic cells is interleukin-1α-dependent in mice.

Botelho FM, Nikota JK, Bauer CM, Morissette MC, Iwakura Y, Kolbeck R, Finch D, Humbles AA, Stämpfli MR.

Respir Res. 2012 Sep 19;13:81. doi: 10.1186/1465-9921-13-81.


Using ensemble models to classify the sentiment expressed in suicide notes.

McCart JA, Finch DK, Jarman J, Hickling E, Lind JD, Richardson MR, Berndt DJ, Luther SL.

Biomed Inform Insights. 2012;5(Suppl. 1):77-85. doi: 10.4137/BII.S8931. Epub 2012 Jan 30.


IL-1α/IL-1R1 expression in chronic obstructive pulmonary disease and mechanistic relevance to smoke-induced neutrophilia in mice.

Botelho FM, Bauer CM, Finch D, Nikota JK, Zavitz CC, Kelly A, Lambert KN, Piper S, Foster ML, Goldring JJ, Wedzicha JA, Bassett J, Bramson J, Iwakura Y, Sleeman M, Kolbeck R, Coyle AJ, Humbles AA, Stämpfli MR.

PLoS One. 2011;6(12):e28457. doi: 10.1371/journal.pone.0028457. Epub 2011 Dec 6.


Using statistical text mining to supplement the development of an ontology.

Luther S, Berndt D, Finch D, Richardson M, Hickling E, Hickam D.

J Biomed Inform. 2011 Dec;44 Suppl 1:S86-93. doi: 10.1016/j.jbi.2011.11.001. Epub 2011 Nov 15.


CK2 phosphorylation of XRCC1 facilitates dissociation from DNA and single-strand break formation during base excision repair.

Ström CE, Mortusewicz O, Finch D, Parsons JL, Lagerqvist A, Johansson F, Schultz N, Erixon K, Dianov GL, Helleday T.

DNA Repair (Amst). 2011 Sep 5;10(9):961-9. doi: 10.1016/j.dnarep.2011.07.004. Epub 2011 Aug 15.


Whole-molecule antibody engineering: generation of a high-affinity anti-IL-6 antibody with extended pharmacokinetics.

Finch DK, Sleeman MA, Moisan J, Ferraro F, Botterell S, Campbell J, Cochrane D, Cruwys S, England E, Lane S, Rendall E, Sinha M, Walker C, Rees G, Bowen MA, Schneider A, Liang M, Faggioni R, Fung M, Mallinder PR, Wilkinson T, Kolbeck R, Vaughan T, Lowe DC.

J Mol Biol. 2011 Aug 26;411(4):791-807. doi: 10.1016/j.jmb.2011.06.031. Epub 2011 Jun 23.


Engineering a high-affinity anti-IL-15 antibody: crystal structure reveals an α-helix in VH CDR3 as key component of paratope.

Lowe DC, Gerhardt S, Ward A, Hargreaves D, Anderson M, Ferraro F, Pauptit RA, Pattison DV, Buchanan C, Popovic B, Finch DK, Wilkinson T, Sleeman M, Vaughan TJ, Mallinder PR.

J Mol Biol. 2011 Feb 11;406(1):160-75. doi: 10.1016/j.jmb.2010.12.017. Epub 2010 Dec 16.


Identification of a potent anti-IL-15 antibody with opposing mechanisms of action in vitro and in vivo.

Finch DK, Midha A, Buchanan CL, Cochrane D, Craggs RI, Cruwys S, Grahames C, Kolbeck R, Lowe DC, Maltby J, Pattison DV, Vousden KA, Ward A, Sleeman MA, Mallinder PR.

Br J Pharmacol. 2011 Jan;162(2):480-90. doi: 10.1111/j.1476-5381.2010.01061.x.


Referral and treatment rates of neoadjuvant chemotherapy in muscle-invasive bladder cancer before and after publication of a clinical practice guideline.

Miles BJ, Fairey AS, Eliasziw M, Estey EP, Venner P, Finch D, Trpkov K, Eigl BJ.

Can Urol Assoc J. 2010 Aug;4(4):263-7.


Interim report of a phase 2 clinical trial of lenalidomide for T-cell non-Hodgkin lymphoma.

Dueck G, Chua N, Prasad A, Finch D, Stewart D, White D, van der Jagt R, Johnston J, Belch A, Reiman T.

Cancer. 2010 Oct 1;116(19):4541-8. doi: 10.1002/cncr.25377.


XRCC1 phosphorylation by CK2 is required for its stability and efficient DNA repair.

Parsons JL, Dianova II, Finch D, Tait PS, Ström CE, Helleday T, Dianov GL.

DNA Repair (Amst). 2010 Jul 1;9(7):835-41. doi: 10.1016/j.dnarep.2010.04.008. Epub 2010 May 14.


Clinical outcome in metastatic renal cell carcinoma patients after failure of initial vascular endothelial growth factor-targeted therapy.

Vickers MM, Choueiri TK, Rogers M, Percy A, Finch D, Zama I, Cheng T, North S, Knox JJ, Kollmannsberger C, McDermott DF, Rini BI, Heng DY.

Urology. 2010 Aug;76(2):430-4. doi: 10.1016/j.urology.2009.12.031. Epub 2010 Mar 12.


Cells deficient in the base excision repair protein, DNA polymerase beta, are hypersensitive to oxaliplatin chemotherapy.

Yang J, Parsons J, Nicolay NH, Caporali S, Harrington CF, Singh R, Finch D, D'Atri S, Farmer PB, Johnston PG, McKenna WG, Dianov G, Sharma RA.

Oncogene. 2010 Jan 21;29(3):463-8. doi: 10.1038/onc.2009.327. Epub 2009 Oct 19.


Ubiquitin ligase ARF-BP1/Mule modulates base excision repair.

Parsons JL, Tait PS, Finch D, Dianova II, Edelmann MJ, Khoronenkova SV, Kessler BM, Sharma RA, McKenna WG, Dianov GL.

EMBO J. 2009 Oct 21;28(20):3207-15. doi: 10.1038/emboj.2009.243. Epub 2009 Aug 27.

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