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Items: 1 to 50 of 185

1.

Phase 2b Study of Pimodivir (JNJ-63623872) as Monotherapy or in Combination With Oseltamivir for Treatment of Acute Uncomplicated Seasonal Influenza A: TOPAZ Trial.

Finberg RW, Lanno R, Anderson D, Fleischhackl R, van Duijnhoven W, Kauffman RS, Kosoglou T, Vingerhoets J, Leopold L.

J Infect Dis. 2018 Nov 14. doi: 10.1093/infdis/jiy547. [Epub ahead of print]

PMID:
30428049
2.

Mutations in Influenza A Virus Neuraminidase and Hemagglutinin Confer Resistance against a Broadly Neutralizing Hemagglutinin Stem Antibody.

Prachanronarong KL, Canale AS, Liu P, Somasundaran M, Hou S, Poh YP, Han T, Zhu Q, Renzette N, Zeldovich KB, Kowalik TF, Kurt-Yilmaz N, Jensen JD, Bolon DNA, Marasco WA, Finberg RW, Schiffer CA, Wang JP.

J Virol. 2019 Jan 4;93(2). pii: e01639-18. doi: 10.1128/JVI.01639-18. Print 2019 Jan 15.

PMID:
30381484
3.

Synonymous Mutations at the Beginning of the Influenza A Virus Hemagglutinin Gene Impact Experimental Fitness.

Canale AS, Venev SV, Whitfield TW, Caffrey DR, Marasco WA, Schiffer CA, Kowalik TF, Jensen JD, Finberg RW, Zeldovich KB, Wang JP, Bolon DNA.

J Mol Biol. 2018 Apr 13;430(8):1098-1115. doi: 10.1016/j.jmb.2018.02.009. Epub 2018 Feb 18.

PMID:
29466705
4.

Structural Determination of the Broadly Reactive Anti-IGHV1-69 Anti-idiotypic Antibody G6 and Its Idiotope.

Avnir Y, Prachanronarong KL, Zhang Z, Hou S, Peterson EC, Sui J, Zayed H, Kurella VB, McGuire AT, Stamatatos L, Hilbert BJ, Bohn MF, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Goodall M, Jefferis R, Zhu Q, Kurt Yilmaz N, Schiffer CA, Marasco WA.

Cell Rep. 2017 Dec 12;21(11):3243-3255. doi: 10.1016/j.celrep.2017.11.056.

5.

The Combined Effect of Oseltamivir and Favipiravir on Influenza A Virus Evolution.

Ormond L, Liu P, Matuszewski S, Renzette N, Bank C, Zeldovich K, Bolon DN, Kowalik TF, Finberg RW, Jensen JD, Wang JP.

Genome Biol Evol. 2017 Jul 1;9(7):1913-1924. doi: 10.1093/gbe/evx138.

6.

Eliminating Residents Increases the Cost of Care.

DeMarco DM, Forster R, Gakis T, Finberg RW.

J Grad Med Educ. 2017 Aug;9(4):514-517. doi: 10.4300/JGME-D-16-00671.1.

7.

Properdin Levels in Individuals with Chemotherapy-Induced Neutropenia.

Tsyrkunou A, Agarwal S, Koirala B, Finberg RW, Nath R, Barton B, Levitz SM, Wang JP, Ram S.

Open Forum Infect Dis. 2016 Dec 7;4(1):ofw250. doi: 10.1093/ofid/ofw250. eCollection 2017 Winter.

8.

Association of hospital contact precaution policies with emergency department admission time.

Kotkowski K, Ellison RT 3rd, Barysauskas C, Barton B, Allison J, Mack D, Finberg RW, Reznek M.

J Hosp Infect. 2017 Jul;96(3):244-249. doi: 10.1016/j.jhin.2017.03.023. Epub 2017 Mar 24.

PMID:
28454768
9.

Molecular Basis for Differential Patterns of Drug Resistance in Influenza N1 and N2 Neuraminidase.

Prachanronarong KL, Özen A, Thayer KM, Yilmaz LS, Zeldovich KB, Bolon DN, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Kurt-Yilmaz N, Schiffer CA.

J Chem Theory Comput. 2016 Dec 13;12(12):6098-6108. Epub 2016 Nov 17.

PMID:
27951676
10.

An experimental evaluation of drug-induced mutational meltdown as an antiviral treatment strategy.

Bank C, Renzette N, Liu P, Matuszewski S, Shim H, Foll M, Bolon DN, Zeldovich KB, Kowalik TF, Finberg RW, Wang JP, Jensen JD.

Evolution. 2016 Nov;70(11):2470-2484. doi: 10.1111/evo.13041. Epub 2016 Sep 13.

PMID:
27566611
11.

Uveitis and Systemic Inflammatory Markers in Convalescent Phase of Ebola Virus Disease.

Chancellor JR, Padmanabhan SP, Greenough TC, Sacra R, Ellison RT 3rd, Madoff LC, Droms RJ, Hinkle DM, Asdourian GK, Finberg RW, Stroher U, Uyeki TM, Cerón OM.

Emerg Infect Dis. 2016 Feb;22(2):295-7. doi: 10.3201/eid2202.151416.

12.

A Balance between Inhibitor Binding and Substrate Processing Confers Influenza Drug Resistance.

Jiang L, Liu P, Bank C, Renzette N, Prachanronarong K, Yilmaz LS, Caffrey DR, Zeldovich KB, Schiffer CA, Kowalik TF, Jensen JD, Finberg RW, Wang JP, Bolon DNA.

J Mol Biol. 2016 Feb 13;428(3):538-553. doi: 10.1016/j.jmb.2015.11.027. Epub 2015 Dec 4.

PMID:
26656922
13.

Influenza A virus preferentially snatches noncoding RNA caps.

Gu W, Gallagher GR, Dai W, Liu P, Li R, Trombly MI, Gammon DB, Mello CC, Wang JP, Finberg RW.

RNA. 2015 Dec;21(12):2067-75. doi: 10.1261/rna.054221.115. Epub 2015 Oct 1.

14.

A chimeric EBV gp350/220-based VLP replicates the virion B-cell attachment mechanism and elicits long-lasting neutralizing antibodies in mice.

Ogembo JG, Muraswki MR, McGinnes LW, Parcharidou A, Sutiwisesak R, Tison T, Avendano J, Agnani D, Finberg RW, Morrison TG, Fingeroth JD.

J Transl Med. 2015 Feb 6;13:50. doi: 10.1186/s12967-015-0415-2.

15.

Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment.

Zeldovich KB, Liu P, Renzette N, Foll M, Pham ST, Venev SV, Gallagher GR, Bolon DN, Kurt-Jones EA, Jensen JD, Caffrey DR, Schiffer CA, Kowalik TF, Wang JP, Finberg RW.

Mol Biol Evol. 2015 Jun;32(6):1519-32. doi: 10.1093/molbev/msv044. Epub 2015 Feb 23.

16.

Heparin octasaccharide decoy liposomes inhibit replication of multiple viruses.

Hendricks GL, Velazquez L, Pham S, Qaisar N, Delaney JC, Viswanathan K, Albers L, Comolli JC, Shriver Z, Knipe DM, Kurt-Jones EA, Fygenson DK, Trevejo JM, Wang JP, Finberg RW.

Antiviral Res. 2015 Apr;116:34-44. doi: 10.1016/j.antiviral.2015.01.008. Epub 2015 Jan 28.

17.

Viral infection of engrafted human islets leads to diabetes.

Gallagher GR, Brehm MA, Finberg RW, Barton BA, Shultz LD, Greiner DL, Bortell R, Wang JP.

Diabetes. 2015 Apr;64(4):1358-69. doi: 10.2337/db14-1020. Epub 2014 Nov 12.

18.

Increased survival in B-cell-deficient mice during experimental cerebral malaria suggests a role for circulating immune complexes.

de Oliveira RB, Wang JP, Ram S, Gazzinelli RT, Finberg RW, Golenbock DT.

MBio. 2014 Mar 18;5(2):e00949-14. doi: 10.1128/mBio.00949-14.

19.

Influenza virus drug resistance: a time-sampled population genetics perspective.

Foll M, Poh YP, Renzette N, Ferrer-Admetlla A, Bank C, Shim H, Malaspinas AS, Ewing G, Liu P, Wegmann D, Caffrey DR, Zeldovich KB, Bolon DN, Wang JP, Kowalik TF, Schiffer CA, Finberg RW, Jensen JD.

PLoS Genet. 2014 Feb 27;10(2):e1004185. doi: 10.1371/journal.pgen.1004185. eCollection 2014 Feb.

20.

Evolution of the influenza A virus genome during development of oseltamivir resistance in vitro.

Renzette N, Caffrey DR, Zeldovich KB, Liu P, Gallagher GR, Aiello D, Porter AJ, Kurt-Jones EA, Bolon DN, Poh YP, Jensen JD, Schiffer CA, Kowalik TF, Finberg RW, Wang JP.

J Virol. 2014 Jan;88(1):272-81. doi: 10.1128/JVI.01067-13. Epub 2013 Oct 23.

21.

Dephosphorylation of the RNA sensors RIG-I and MDA5 by the phosphatase PP1 is essential for innate immune signaling.

Wies E, Wang MK, Maharaj NP, Chen K, Zhou S, Finberg RW, Gack MU.

Immunity. 2013 Mar 21;38(3):437-49. doi: 10.1016/j.immuni.2012.11.018. Epub 2013 Mar 14.

22.

Tuning innate immune activation by surface texturing of polymer microparticles: the role of shape in inflammasome activation.

Vaine CA, Patel MK, Zhu J, Lee E, Finberg RW, Hayward RC, Kurt-Jones EA.

J Immunol. 2013 Apr 1;190(7):3525-32. doi: 10.4049/jimmunol.1200492. Epub 2013 Feb 20.

23.

Human complement receptor type 1/CD35 is an Epstein-Barr Virus receptor.

Ogembo JG, Kannan L, Ghiran I, Nicholson-Weller A, Finberg RW, Tsokos GC, Fingeroth JD.

Cell Rep. 2013 Feb 21;3(2):371-85. doi: 10.1016/j.celrep.2013.01.023. Epub 2013 Feb 14.

24.

Sialylneolacto-N-tetraose c (LSTc)-bearing liposomal decoys capture influenza A virus.

Hendricks GL, Weirich KL, Viswanathan K, Li J, Shriver ZH, Ashour J, Ploegh HL, Kurt-Jones EA, Fygenson DK, Finberg RW, Comolli JC, Wang JP.

J Biol Chem. 2013 Mar 22;288(12):8061-73. doi: 10.1074/jbc.M112.437202. Epub 2013 Jan 28.

25.

Human monoclonal antibody MBL-HCV1 delays HCV viral rebound following liver transplantation: a randomized controlled study.

Chung RT, Gordon FD, Curry MP, Schiano TD, Emre S, Corey K, Markmann JF, Hertl M, Pomposelli JJ, Pomfret EA, Florman S, Schilsky M, Broering TJ, Finberg RW, Szabo G, Zamore PD, Khettry U, Babcock GJ, Ambrosino DM, Leav B, Leney M, Smith HL, Molrine DC.

Am J Transplant. 2013 Apr;13(4):1047-1054. doi: 10.1111/ajt.12083. Epub 2013 Jan 28.

26.

Phomopsis bougainvilleicola prepatellar bursitis in a renal transplant recipient.

Cariello PF, Wickes BL, Sutton DA, Castlebury LA, Levitz SM, Finberg RW, Thompson EH, Daly JS.

J Clin Microbiol. 2013 Feb;51(2):692-5. doi: 10.1128/JCM.02674-12. Epub 2012 Nov 28.

27.

Human monoclonal antibody HCV1 effectively prevents and treats HCV infection in chimpanzees.

Morin TJ, Broering TJ, Leav BA, Blair BM, Rowley KJ, Boucher EN, Wang Y, Cheslock PS, Knauber M, Olsen DB, Ludmerer SW, Szabo G, Finberg RW, Purcell RH, Lanford RE, Ambrosino DM, Molrine DC, Babcock GJ.

PLoS Pathog. 2012;8(8):e1002895. doi: 10.1371/journal.ppat.1002895. Epub 2012 Aug 30.

28.

Role of interferon regulatory factor 7 in T cell responses during acute lymphocytic choriomeningitis virus infection.

Zhou S, Cerny AM, Fitzgerald KA, Kurt-Jones EA, Finberg RW.

J Virol. 2012 Oct;86(20):11254-65. Epub 2012 Aug 8.

29.

CD14 deficiency impacts glucose homeostasis in mice through altered adrenal tone.

Young JL, Mora A, Cerny A, Czech MP, Woda B, Kurt-Jones EA, Finberg RW, Corvera S.

PLoS One. 2012;7(1):e29688. doi: 10.1371/journal.pone.0029688. Epub 2012 Jan 13.

30.

Role of specific innate immune responses in herpes simplex virus infection of the central nervous system.

Wang JP, Bowen GN, Zhou S, Cerny A, Zacharia A, Knipe DM, Finberg RW, Kurt-Jones EA.

J Virol. 2012 Feb;86(4):2273-81. doi: 10.1128/JVI.06010-11. Epub 2011 Dec 14.

31.

C21orf91 genotypes correlate with herpes simplex labialis (cold sore) frequency: description of a cold sore susceptibility gene.

Kriesel JD, Jones BB, Matsunami N, Patel MK, St Pierre CA, Kurt-Jones EA, Finberg RW, Leppert M, Hobbs MR.

J Infect Dis. 2011 Dec 1;204(11):1654-62. doi: 10.1093/infdis/jir633.

32.

Contributions of the MyD88-dependent receptors IL-18R, IL-1R, and TLR9 to host defenses following pulmonary challenge with Cryptococcus neoformans.

Wang JP, Lee CK, Akalin A, Finberg RW, Levitz SM.

PLoS One. 2011;6(10):e26232. doi: 10.1371/journal.pone.0026232. Epub 2011 Oct 19.

33.

LPLUNC1 modulates innate immune responses to Vibrio cholerae.

Shin OS, Uddin T, Citorik R, Wang JP, Della Pelle P, Kradin RL, Bingle CD, Bingle L, Camilli A, Bhuiyan TR, Shirin T, Ryan ET, Calderwood SB, Finberg RW, Qadri F, Larocque RC, Harris JB.

J Infect Dis. 2011 Nov;204(9):1349-57. doi: 10.1093/infdis/jir544. Epub 2011 Sep 7.

34.

Antibodies to cell surface proteins redirect intracellular trafficking pathways.

St Pierre CA, Leonard D, Corvera S, Kurt-Jones EA, Finberg RW.

Exp Mol Pathol. 2011 Dec;91(3):723-32. doi: 10.1016/j.yexmp.2011.05.011. Epub 2011 Jul 23.

35.

Assembly and immunological properties of Newcastle disease virus-like particles containing the respiratory syncytial virus F and G proteins.

McGinnes LW, Gravel KA, Finberg RW, Kurt-Jones EA, Massare MJ, Smith G, Schmidt MR, Morrison TG.

J Virol. 2011 Jan;85(1):366-77. doi: 10.1128/JVI.01861-10. Epub 2010 Oct 27.

36.

Periprosthetic osteolysis: characterizing the innate immune response to titanium wear-particles.

St Pierre CA, Chan M, Iwakura Y, Ayers DC, Kurt-Jones EA, Finberg RW.

J Orthop Res. 2010 Nov;28(11):1418-24. doi: 10.1002/jor.21149. Erratum in: J Orthop Res. 2011 Jan;29(1):154.

37.

Abnormal immune complex processing and spontaneous glomerulonephritis in complement factor H-deficient mice with human complement receptor 1 on erythrocytes.

Alexander JJ, Hack BK, Jacob A, Chang A, Haas M, Finberg RW, Quigg RJ.

J Immunol. 2010 Sep 15;185(6):3759-67. doi: 10.4049/jimmunol.1000683. Epub 2010 Aug 11.

38.

Herpes simplex virus immediate-early ICP0 protein inhibits Toll-like receptor 2-dependent inflammatory responses and NF-kappaB signaling.

van Lint AL, Murawski MR, Goodbody RE, Severa M, Fitzgerald KA, Finberg RW, Knipe DM, Kurt-Jones EA.

J Virol. 2010 Oct;84(20):10802-11. doi: 10.1128/JVI.00063-10. Epub 2010 Aug 4.

39.

Discovery of a novel TLR2 signaling inhibitor with anti-viral activity.

Zhou S, Cerny AM, Bowen G, Chan M, Knipe DM, Kurt-Jones EA, Finberg RW.

Antiviral Res. 2010 Sep;87(3):295-306. doi: 10.1016/j.antiviral.2010.06.011. Epub 2010 Jul 23.

40.

Induction and inhibition of type I interferon responses by distinct components of lymphocytic choriomeningitis virus.

Zhou S, Cerny AM, Zacharia A, Fitzgerald KA, Kurt-Jones EA, Finberg RW.

J Virol. 2010 Sep;84(18):9452-62. doi: 10.1128/JVI.00155-10. Epub 2010 Jun 30.

41.

Complement receptor 1 is a sialic acid-independent erythrocyte receptor of Plasmodium falciparum.

Spadafora C, Awandare GA, Kopydlowski KM, Czege J, Moch JK, Finberg RW, Tsokos GC, Stoute JA.

PLoS Pathog. 2010 Jun 17;6(6):e1000968. doi: 10.1371/journal.ppat.1000968.

42.

Complement receptor 1 expression on mouse erythrocytes mediates clearance of Streptococcus pneumoniae by immune adherence.

Li J, Wang JP, Ghiran I, Cerny A, Szalai AJ, Briles DE, Finberg RW.

Infect Immun. 2010 Jul;78(7):3129-35. doi: 10.1128/IAI.01263-09. Epub 2010 May 3.

43.

R753Q single-nucleotide polymorphism impairs toll-like receptor 2 recognition of hepatitis C virus core and nonstructural 3 proteins.

Brown RA, Gralewski JH, Eid AJ, Knoll BM, Finberg RW, Razonable RR.

Transplantation. 2010 Apr 15;89(7):811-5. doi: 10.1097/TP.0b013e3181cbac18.

44.

Newcastle disease virus-like particles containing respiratory syncytial virus G protein induced protection in BALB/c mice, with no evidence of immunopathology.

Murawski MR, McGinnes LW, Finberg RW, Kurt-Jones EA, Massare MJ, Smith G, Heaton PM, Fraire AE, Morrison TG.

J Virol. 2010 Jan;84(2):1110-23. doi: 10.1128/JVI.01709-09. Epub 2009 Nov 4.

45.

MDA5 and MAVS mediate type I interferon responses to coxsackie B virus.

Wang JP, Cerny A, Asher DR, Kurt-Jones EA, Bronson RT, Finberg RW.

J Virol. 2010 Jan;84(1):254-60. doi: 10.1128/JVI.00631-09.

46.

Identification and characterization of broadly neutralizing human monoclonal antibodies directed against the E2 envelope glycoprotein of hepatitis C virus.

Broering TJ, Garrity KA, Boatright NK, Sloan SE, Sandor F, Thomas WD Jr, Szabo G, Finberg RW, Ambrosino DM, Babcock GJ.

J Virol. 2009 Dec;83(23):12473-82. doi: 10.1128/JVI.01138-09. Epub 2009 Sep 16.

47.

Antiviral responses: different roles for different tolls.

Finberg RW, Wang JP.

Immunity. 2009 Feb 20;30(2):173-5. doi: 10.1016/j.immuni.2009.02.001.

48.

Human erythrocytes bind and inactivate type 5 adenovirus by presenting Coxsackie virus-adenovirus receptor and complement receptor 1.

Carlisle RC, Di Y, Cerny AM, Sonnen AF, Sim RB, Green NK, Subr V, Ulbrich K, Gilbert RJ, Fisher KD, Finberg RW, Seymour LW.

Blood. 2009 Feb 26;113(9):1909-18. doi: 10.1182/blood-2008-09-178459. Epub 2009 Jan 8.

49.

The cell adhesion molecule "CAR" and sialic acid on human erythrocytes influence adenovirus in vivo biodistribution.

Seiradake E, Henaff D, Wodrich H, Billet O, Perreau M, Hippert C, Mennechet F, Schoehn G, Lortat-Jacob H, Dreja H, Ibanes S, Kalatzis V, Wang JP, Finberg RW, Cusack S, Kremer EJ.

PLoS Pathog. 2009 Jan;5(1):e1000277. doi: 10.1371/journal.ppat.1000277. Epub 2009 Jan 2.

50.

MyD88 intrinsically regulates CD4 T-cell responses.

Zhou S, Kurt-Jones EA, Cerny AM, Chan M, Bronson RT, Finberg RW.

J Virol. 2009 Feb;83(4):1625-34. doi: 10.1128/JVI.01770-08. Epub 2008 Dec 3.

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