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Items: 19


Correction for Olsen et al., "Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication".

Olsen ME, Filone CM, Rozelle D, Mire CE, Agans KN, Hensley L, Connor JH.

MBio. 2018 Jun 5;9(3). pii: e01065-18. doi: 10.1128/mBio.01065-18. No abstract available.


Two-Center Evaluation of Disinfectant Efficacy against Ebola Virus in Clinical and Laboratory Matrices.

Smither SJ, Eastaugh L, Filone CM, Freeburger D, Herzog A, Lever MS, Miller DM, Mitzel D, Noah JW, Reddick-Elick MS, Reese A, Schuit M, Wlazlowski CB, Hevey M, Wahl-Jensen V.

Emerg Infect Dis. 2018 Jan;24(1). doi: 10.3201/eid2401.170504.


A Semi-automated High-Throughput Microtitration Assay for Filoviruses.

Filone CM, Miller D, Wahl-Jensen V.

Methods Mol Biol. 2017;1628:163-175. doi: 10.1007/978-1-4939-7116-9_12.


Polyamines and Hypusination Are Required for Ebolavirus Gene Expression and Replication.

Olsen ME, Filone CM, Rozelle D, Mire CE, Agans KN, Hensley L, Connor JH.

MBio. 2016 Jul 26;7(4). pii: e00882-16. doi: 10.1128/mBio.00882-16. Erratum in: MBio. 2018 Jun 5;9(3):.


Differences in the Comparative Stability of Ebola Virus Makona-C05 and Yambuku-Mayinga in Blood.

Schuit M, Miller DM, Reddick-Elick MS, Wlazlowski CB, Filone CM, Herzog A, Colf LA, Wahl-Jensen V, Hevey M, Noah JW.

PLoS One. 2016 Feb 5;11(2):e0148476. doi: 10.1371/journal.pone.0148476. eCollection 2016.


Probing the virus host interaction in high containment: an approach using pooled short hairpin RNA.

Filone CM, Dower K, Cowley GS, Hensley LE, Connor JH.

Assay Drug Dev Technol. 2015 Jan-Feb;13(1):34-43. doi: 10.1089/adt.2014.613. Epub 2015 Feb 3.


Discovery of a novel compound with anti-venezuelan equine encephalitis virus activity that targets the nonstructural protein 2.

Chung DH, Jonsson CB, Tower NA, Chu YK, Sahin E, Golden JE, Noah JW, Schroeder CE, Sotsky JB, Sosa MI, Cramer DE, McKellip SN, Rasmussen L, White EL, Schmaljohn CS, Julander JG, Smith JM, Filone CM, Connor JH, Sakurai Y, Davey RA.

PLoS Pathog. 2014 Jun 26;10(6):e1004213. doi: 10.1371/journal.ppat.1004213. eCollection 2014 Jun.


Vaccinia reporter viruses for quantifying viral function at all stages of gene expression.

Rozelle DK, Filone CM, Dower K, Connor JH.

J Vis Exp. 2014 May 15;(87). doi: 10.3791/51522.


Activation of stress response pathways promotes formation of antiviral granules and restricts virus replication.

Rozelle DK, Filone CM, Kedersha N, Connor JH.

Mol Cell Biol. 2014 Jun;34(11):2003-16. doi: 10.1128/MCB.01630-13. Epub 2014 Mar 24.


The master regulator of the cellular stress response (HSF1) is critical for orthopoxvirus infection.

Filone CM, Caballero IS, Dower K, Mendillo ML, Cowley GS, Santagata S, Rozelle DK, Yen J, Rubins KH, Hacohen N, Root DE, Hensley LE, Connor J.

PLoS Pathog. 2014 Feb 6;10(2):e1003904. doi: 10.1371/journal.ppat.1003904. eCollection 2014 Feb.


Identification of a broad-spectrum inhibitor of viral RNA synthesis: validation of a prototype virus-based approach.

Filone CM, Hodges EN, Honeyman B, Bushkin GG, Boyd K, Platt A, Ni F, Strom K, Hensley L, Snyder JK, Connor JH.

Chem Biol. 2013 Mar 21;20(3):424-33. doi: 10.1016/j.chembiol.2013.02.011.


Filoviruses require endosomal cysteine proteases for entry but exhibit distinct protease preferences.

Misasi J, Chandran K, Yang JY, Considine B, Filone CM, Côté M, Sullivan N, Fabozzi G, Hensley L, Cunningham J.

J Virol. 2012 Mar;86(6):3284-92. doi: 10.1128/JVI.06346-11. Epub 2012 Jan 11.


Identification of a pyridopyrimidinone inhibitor of orthopoxviruses from a diversity-oriented synthesis library.

Dower K, Filone CM, Hodges EN, Bjornson ZB, Rubins KH, Brown LE, Schaus S, Hensley LE, Connor JH.

J Virol. 2012 Mar;86(5):2632-40. doi: 10.1128/JVI.05416-11. Epub 2011 Dec 28.


Small molecule inhibitors reveal Niemann-Pick C1 is essential for Ebola virus infection.

Côté M, Misasi J, Ren T, Bruchez A, Lee K, Filone CM, Hensley L, Li Q, Ory D, Chandran K, Cunningham J.

Nature. 2011 Aug 24;477(7364):344-8. doi: 10.1038/nature10380.


Rift valley fever virus infection of human cells and insect hosts is promoted by protein kinase C epsilon.

Filone CM, Hanna SL, Caino MC, Bambina S, Doms RW, Cherry S.

PLoS One. 2010 Nov 24;5(11):e15483. doi: 10.1371/journal.pone.0015483.


Polybasic KKR motif in the cytoplasmic tail of Nipah virus fusion protein modulates membrane fusion by inside-out signaling.

Aguilar HC, Matreyek KA, Choi DY, Filone CM, Young S, Lee B.

J Virol. 2007 May;81(9):4520-32. Epub 2007 Feb 14.


Development and characterization of a Rift Valley fever virus cell-cell fusion assay using alphavirus replicon vectors.

Filone CM, Heise M, Doms RW, Bertolotti-Ciarlet A.

Virology. 2006 Dec 5-20;356(1-2):155-64. Epub 2006 Aug 30.


N-glycans on Nipah virus fusion protein protect against neutralization but reduce membrane fusion and viral entry.

Aguilar HC, Matreyek KA, Filone CM, Hashimi ST, Levroney EL, Negrete OA, Bertolotti-Ciarlet A, Choi DY, McHardy I, Fulcher JA, Su SV, Wolf MC, Kohatsu L, Baum LG, Lee B.

J Virol. 2006 May;80(10):4878-89.


Presence of broadly reactive and group-specific neutralizing epitopes on newly described isolates of Crimean-Congo hemorrhagic fever virus.

Ahmed AA, McFalls JM, Hoffmann C, Filone CM, Stewart SM, Paragas J, Khodjaev S, Shermukhamedova D, Schmaljohn CS, Doms RW, Bertolotti-Ciarlet A.

J Gen Virol. 2005 Dec;86(Pt 12):3327-36.


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