Format
Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 95

1.

Identification of diterpenoid compounds that interfere with Fli-1 DNA binding to suppress leukemogenesis.

Liu T, Xia L, Yao Y, Yan C, Fan Y, Gajendran B, Yang J, Li YJ, Chen J, Filmus J, Spaner DE, Zacksenhaus E, Hao X, Ben-David Y.

Cell Death Dis. 2019 Feb 11;10(2):117. doi: 10.1038/s41419-019-1363-1.

2.

Novel flavagline-like compounds with potent Fli-1 inhibitory activity suppress diverse types of leukemia.

Song J, Yuan C, Yang J, Liu T, Yao Y, Xiao X, Gajendran B, Xu D, Li YJ, Wang C, Liu W, Wen M, Spaner D, Filmus J, Zacksenhaus E, Zhang Y, Hao X, Ben-David Y.

FEBS J. 2018 Dec;285(24):4631-4645. doi: 10.1111/febs.14690. Epub 2018 Nov 20.

PMID:
30387554
3.

Glypican-6 promotes the growth of developing long bones by stimulating Hedgehog signaling.

Capurro M, Izumikawa T, Suarez P, Shi W, Cydzik M, Kaneiwa T, Gariepy J, Bonafe L, Filmus J.

J Cell Biol. 2017 Sep 4;216(9):2911-2926. doi: 10.1083/jcb.201605119. Epub 2017 Jul 10.

4.

The Heparan Sulfate Proteoglycan Glypican-6 Is Upregulated in the Failing Heart, and Regulates Cardiomyocyte Growth through ERK1/2 Signaling.

Melleby AO, Strand ME, Romaine A, Herum KM, Skrbic B, Dahl CP, Sjaastad I, Fiane AE, Filmus J, Christensen G, Lunde IG.

PLoS One. 2016 Oct 21;11(10):e0165079. doi: 10.1371/journal.pone.0165079. eCollection 2016.

5.

Insights into the key roles of proteoglycans in breast cancer biology and translational medicine.

Theocharis AD, Skandalis SS, Neill T, Multhaupt HA, Hubo M, Frey H, Gopal S, Gomes A, Afratis N, Lim HC, Couchman JR, Filmus J, Sanderson RD, Schaefer L, Iozzo RV, Karamanos NK.

Biochim Biophys Acta. 2015 Apr;1855(2):276-300. doi: 10.1016/j.bbcan.2015.03.006. Epub 2015 Mar 28. Review.

6.

Processing by convertases is required for glypican-3-induced inhibition of Hedgehog signaling.

Capurro M, Shi W, Izumikawa T, Kitagawa H, Filmus J.

J Biol Chem. 2015 Mar 20;290(12):7576-85. doi: 10.1074/jbc.M114.612705. Epub 2015 Feb 4.

7.

Glypican-3 binds to Frizzled and plays a direct role in the stimulation of canonical Wnt signaling.

Capurro M, Martin T, Shi W, Filmus J.

J Cell Sci. 2014 Apr 1;127(Pt 7):1565-75. doi: 10.1242/jcs.140871. Epub 2014 Feb 4.

8.

The role of glypicans in Hedgehog signaling.

Filmus J, Capurro M.

Matrix Biol. 2014 Apr;35:248-52. doi: 10.1016/j.matbio.2013.12.007. Epub 2014 Jan 8. Review.

9.

X-linked congenital ptosis and associated intellectual disability, short stature, microcephaly, cleft palate, digital and genital abnormalities define novel Xq25q26 duplication syndrome.

Møller RS, Jensen LR, Maas SM, Filmus J, Capurro M, Hansen C, Marcelis CL, Ravn K, Andrieux J, Mathieu M, Kirchhoff M, Rødningen OK, de Leeuw N, Yntema HG, Froyen G, Vandewalle J, Ballon K, Klopocki E, Joss S, Tolmie J, Knegt AC, Lund AM, Hjalgrim H, Kuss AW, Tommerup N, Ullmann R, de Brouwer AP, Strømme P, Kjaergaard S, Tümer Z, Kleefstra T.

Hum Genet. 2014 May;133(5):625-38. doi: 10.1007/s00439-013-1403-3. Epub 2013 Dec 11.

PMID:
24326587
10.

Regulation of bone morphogenetic protein signalling and cranial osteogenesis by Gpc1 and Gpc3.

Dwivedi PP, Grose RH, Filmus J, Hii CS, Xian CJ, Anderson PJ, Powell BC.

Bone. 2013 Aug;55(2):367-76. doi: 10.1016/j.bone.2013.04.013. Epub 2013 Apr 25.

PMID:
23624389
11.

Glypican-3: a marker and a therapeutic target in hepatocellular carcinoma.

Filmus J, Capurro M.

FEBS J. 2013 May;280(10):2471-6. doi: 10.1111/febs.12126. Epub 2013 Jan 31. Review.

12.

LRP1 mediates Hedgehog-induced endocytosis of the GPC3-Hedgehog complex.

Capurro MI, Shi W, Filmus J.

J Cell Sci. 2012 Jul 15;125(Pt 14):3380-9. doi: 10.1242/jcs.098889. Epub 2012 Mar 30.

13.

Therapeutic potential of targeting glypican-3 in hepatocellular carcinoma.

Allegretta M, Filmus J.

Anticancer Agents Med Chem. 2011 Jul;11(6):543-8. Review.

14.

Glypican-5 stimulates rhabdomyosarcoma cell proliferation by activating Hedgehog signaling.

Li F, Shi W, Capurro M, Filmus J.

J Cell Biol. 2011 Feb 21;192(4):691-704. doi: 10.1083/jcb.201008087.

15.

Soluble glypican 3 inhibits the growth of hepatocellular carcinoma in vitro and in vivo.

Zittermann SI, Capurro MI, Shi W, Filmus J.

Int J Cancer. 2010 Mar 15;126(6):1291-301. doi: 10.1002/ijc.24941.

16.

Overgrowth of a mouse model of Simpson-Golabi-Behmel syndrome is partly mediated by Indian hedgehog.

Capurro MI, Li F, Filmus J.

EMBO Rep. 2009 Aug;10(8):901-7. doi: 10.1038/embor.2009.98. Epub 2009 Jul 10.

17.
18.

The role of glypican-3 in the regulation of body size and cancer.

Filmus J, Capurro M.

Cell Cycle. 2008 Sep 15;7(18):2787-90. Epub 2008 Sep 23.

PMID:
18787398
19.

Expression pattern of glypican-3 (GPC3) during human embryonic and fetal development.

Iglesias BV, Centeno G, Pascuccelli H, Ward F, Peters MG, Filmus J, Puricelli L, de Kier Joffé EB.

Histol Histopathol. 2008 Nov;23(11):1333-40. doi: 10.14670/HH-23.1333.

PMID:
18785116
20.

Immunohistochemical study of glypican 3 in thyroid cancer.

Yamanaka K, Ito Y, Okuyama N, Noda K, Matsumoto H, Yoshida H, Miyauchi A, Capurro M, Filmus J, Miyoshi E.

Oncology. 2007;73(5-6):389-94. doi: 10.1159/000136159. Epub 2008 May 30.

PMID:
18511877
21.

Glypicans.

Filmus J, Capurro M, Rast J.

Genome Biol. 2008;9(5):224. doi: 10.1186/gb-2008-9-5-224. Epub 2008 May 22. Review.

22.

Glypican-3 inhibits Hedgehog signaling during development by competing with patched for Hedgehog binding.

Capurro MI, Xu P, Shi W, Li F, Jia A, Filmus J.

Dev Cell. 2008 May;14(5):700-11. doi: 10.1016/j.devcel.2008.03.006.

23.

Glypican-3 regulates migration, adhesion and actin cytoskeleton organization in mammary tumor cells through Wnt signaling modulation.

Stigliano I, Puricelli L, Filmus J, Sogayar MC, Bal de Kier Joffé E, Peters MG.

Breast Cancer Res Treat. 2009 Mar;114(2):251-62. doi: 10.1007/s10549-008-0009-2. Epub 2008 Apr 11.

PMID:
18404367
24.

Mammalian Notum induces the release of glypicans and other GPI-anchored proteins from the cell surface.

Traister A, Shi W, Filmus J.

Biochem J. 2008 Mar 15;410(3):503-11.

PMID:
17967162
25.

Critical role for Fas-associated death domain-like interleukin-1-converting enzyme-like inhibitory protein in anoikis resistance and distant tumor formation.

Mawji IA, Simpson CD, Hurren R, Gronda M, Williams MA, Filmus J, Jonkman J, Da Costa RS, Wilson BC, Thomas MP, Reed JC, Glinsky GV, Schimmer AD.

J Natl Cancer Inst. 2007 May 16;99(10):811-22.

PMID:
17505076
26.

Processing by convertases is not required for glypican-3-induced stimulation of hepatocellular carcinoma growth.

Capurro MI, Shi W, Sandal S, Filmus J.

J Biol Chem. 2005 Dec 16;280(50):41201-6. Epub 2005 Oct 14.

27.

ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.

Liu Z, Li H, Derouet M, Filmus J, LaCasse EC, Korneluk RG, Kerbel RS, Rosen KV.

J Biol Chem. 2005 Nov 11;280(45):37383-92. Epub 2005 Aug 22.

28.

Glypican-3 promotes the growth of hepatocellular carcinoma by stimulating canonical Wnt signaling.

Capurro MI, Xiang YY, Lobe C, Filmus J.

Cancer Res. 2005 Jul 15;65(14):6245-54.

29.

Glypican-3 modulates inhibitory Bmp2-Smad signaling to control renal development in vivo.

Hartwig S, Hu MC, Cella C, Piscione T, Filmus J, Rosenblum ND.

Mech Dev. 2005 Jul;122(7-8):928-38.

30.

Glypican-3 and alphafetoprotein as diagnostic tests for hepatocellular carcinoma.

Filmus J, Capurro M.

Mol Diagn. 2004;8(4):207-12. Review.

PMID:
15887976
31.
32.
33.

Glypican-3 as a serum marker for hepatocellular carcinoma.

Capurro M, Filmus J.

Cancer Res. 2005 Jan 1;65(1):372; author reply 372-3. No abstract available.

34.

The loss of glypican-3 induces alterations in Wnt signaling.

Song HH, Shi W, Xiang YY, Filmus J.

J Biol Chem. 2005 Jan 21;280(3):2116-25. Epub 2004 Nov 10.

35.
36.

Inhibition of invasion and metastasis by glypican-3 in a syngeneic breast cancer model.

Peters MG, Farías E, Colombo L, Filmus J, Puricelli L, Bal de Kier Joffé E.

Breast Cancer Res Treat. 2003 Jul;80(2):221-32.

PMID:
12908826
37.

Glypican-3: a novel serum and histochemical marker for hepatocellular carcinoma.

Capurro M, Wanless IR, Sherman M, Deboer G, Shi W, Miyoshi E, Filmus J.

Gastroenterology. 2003 Jul;125(1):89-97.

PMID:
12851874
38.

The heparan sulfate proteoglycan GPC3 is a potential lung tumor suppressor.

Kim H, Xu GL, Borczuk AC, Busch S, Filmus J, Capurro M, Brody JS, Lange J, D'Armiento JM, Rothman PB, Powell CA.

Am J Respir Cell Mol Biol. 2003 Dec;29(6):694-701. Epub 2003 Jun 19.

PMID:
12816733
39.

The role of glypicans in mammalian development.

Song HH, Filmus J.

Biochim Biophys Acta. 2002 Dec 19;1573(3):241-6. Review.

PMID:
12417406
40.
41.

Increased Bcl-xL expression mediates v-Src-induced resistance to anoikis in intestinal epithelial cells.

Coll ML, Rosen K, Ladeda V, Filmus J.

Oncogene. 2002 Apr 25;21(18):2908-13.

42.

Oligonucleotide microarray analysis of lung adenocarcinoma in smokers and nonsmokers identifies GPC3 as a potential lung tumor suppressor.

Powell CA, Xu G, Filmus J, Busch S, Brody JS, Rothman PB.

Chest. 2002 Mar;121(3 Suppl):6S-7S. No abstract available.

PMID:
11893651
43.

Glypican-3 expression is silenced in human breast cancer.

Xiang YY, Ladeda V, Filmus J.

Oncogene. 2001 Nov 1;20(50):7408-12.

44.

Glypicans: proteoglycans with a surprise.

Filmus J, Selleck SB.

J Clin Invest. 2001 Aug;108(4):497-501. Review. No abstract available.

46.

Myc potentiates apoptosis by stimulating Bax activity at the mitochondria.

Soucie EL, Annis MG, Sedivy J, Filmus J, Leber B, Andrews DW, Penn LZ.

Mol Cell Biol. 2001 Jul;21(14):4725-36.

47.

Induction of anoikis and suppression of human ovarian tumor growth in vivo by down-regulation of Bcl-X(L).

Frankel A, Rosen K, Filmus J, Kerbel RS.

Cancer Res. 2001 Jun 15;61(12):4837-41.

48.

Glypicans in growth control and cancer.

Filmus J.

Glycobiology. 2001 Mar;11(3):19R-23R. Review.

PMID:
11320054
49.

Glypican-3 modulates BMP- and FGF-mediated effects during renal branching morphogenesis.

Grisaru S, Cano-Gauci D, Tee J, Filmus J, Rosenblum ND.

Dev Biol. 2001 Mar 1;231(1):31-46.

50.

Collateral expression of proangiogenic and tumorigenic properties in intestinal epithelial cell variants selected for resistance to anoikis.

Rak J, Mitsuhashi Y, Sheehan C, Krestow JK, Florenes VA, Filmus J, Kerbel RS.

Neoplasia. 1999 Apr;1(1):23-30.

Supplemental Content

Loading ...
Support Center