Sort by
Items per page

Send to

Choose Destination

Search results

Items: 1 to 50 of 157


Delivery of the Pseudomonas aeruginosa Phospholipase Effectors PldA and PldB in a VgrG- and H2-T6SS-Dependent Manner.

Wettstadt S, Wood TE, Fecht S, Filloux A.

Front Microbiol. 2019 Jul 31;10:1718. doi: 10.3389/fmicb.2019.01718. eCollection 2019.


PAAR proteins act as the 'sorting hat' of the type VI secretion system.

Wood TE, Howard SA, Wettstadt S, Filloux A.

Microbiology. 2019 Aug 5. doi: 10.1099/mic.0.000842. [Epub ahead of print]


Cyclic di-GMP inactivates T6SS and T4SS activity in Agrobacterium tumefaciens.

McCarthy RR, Yu M, Eilers K, Wang YC, Lai EM, Filloux A.

Mol Microbiol. 2019 Aug;112(2):632-648. doi: 10.1111/mmi.14279. Epub 2019 Jun 4.


Chronic infection by controlling inflammation.

Filloux A, Davies JC.

Nat Microbiol. 2019 Mar;4(3):378-379. doi: 10.1038/s41564-019-0397-6. No abstract available.


Biofilms 2018: A diversity of microbes and mechanisms.

Fuqua C, Filloux A, Ghigo JM, Visick KL.

J Bacteriol. 2019 Feb 19. pii: JB.00118-19. doi: 10.1128/JB.00118-19. [Epub ahead of print] Review.


The Pseudomonas aeruginosa T6SS-VgrG1b spike is topped by a PAAR protein eliciting DNA damage to bacterial competitors.

Pissaridou P, Allsopp LP, Wettstadt S, Howard SA, Mavridou DAI, Filloux A.

Proc Natl Acad Sci U S A. 2018 Dec 4;115(49):12519-12524. doi: 10.1073/pnas.1814181115. Epub 2018 Nov 19.


Rapid detection of colistin resistance in Acinetobacter baumannii using MALDI-TOF-based lipidomics on intact bacteria.

Dortet L, Potron A, Bonnin RA, Plesiat P, Naas T, Filloux A, Larrouy-Maumus G.

Sci Rep. 2018 Nov 15;8(1):16910. doi: 10.1038/s41598-018-35041-y.


Higher Prevalence of PldA, a Pseudomonas aeruginosa Trans-Kingdom H2-Type VI Secretion System Effector, in Clinical Isolates Responsible for Acute Infections and in Multidrug Resistant Strains.

Boulant T, Boudehen YM, Filloux A, Plesiat P, Naas T, Dortet L.

Front Microbiol. 2018 Oct 29;9:2578. doi: 10.3389/fmicb.2018.02578. eCollection 2018.


Importance of flagella in acute and chronic Pseudomonas aeruginosa infections.

Lorenz A, Preuße M, Bruchmann S, Pawar V, Grahl N, Pils MC, Nolan LM, Filloux A, Weiss S, Häussler S.

Environ Microbiol. 2019 Mar;21(3):883-897. doi: 10.1111/1462-2920.14468. Epub 2018 Dec 3.


A global genomic approach uncovers novel components for twitching motility-mediated biofilm expansion in Pseudomonas aeruginosa.

Nolan LM, Whitchurch CB, Barquist L, Katrib M, Boinett CJ, Mayho M, Goulding D, Charles IG, Filloux A, Parkhill J, Cain AK.

Microb Genom. 2018 Nov;4(11). doi: 10.1099/mgen.0.000229. Epub 2018 Nov 1.


Rapid detection and discrimination of chromosome- and MCR-plasmid-mediated resistance to polymyxins by MALDI-TOF MS in Escherichia coli: the MALDIxin test.

Dortet L, Bonnin RA, Pennisi I, Gauthier L, Jousset AB, Dabos L, Furniss RCD, Mavridou DAI, Bogaerts P, Glupczynski Y, Potron A, Plesiat P, Beyrouthy R, Robin F, Bonnet R, Naas T, Filloux A, Larrouy-Maumus G.

J Antimicrob Chemother. 2018 Dec 1;73(12):3359-3367. doi: 10.1093/jac/dky330.


Shigella-Induced Emergency Granulopoiesis Protects Zebrafish Larvae from Secondary Infection.

Willis AR, Torraca V, Gomes MC, Shelley J, Mazon-Moya M, Filloux A, Lo Celso C, Mostowy S.

MBio. 2018 Jun 26;9(3). pii: e00933-18. doi: 10.1128/mBio.00933-18.


TagF-mediated repression of bacterial type VI secretion systems involves a direct interaction with the cytoplasmic protein Fha.

Lin JS, Pissaridou P, Wu HH, Tsai MD, Filloux A, Lai EM.

J Biol Chem. 2018 Jun 8;293(23):8829-8842. doi: 10.1074/jbc.RA117.001618. Epub 2018 Mar 29.


Pore-forming activity of the Pseudomonas aeruginosa type III secretion system translocon alters the host epigenome.

Dortet L, Lombardi C, Cretin F, Dessen A, Filloux A.

Nat Microbiol. 2018 Mar;3(3):378-386. doi: 10.1038/s41564-018-0109-7. Epub 2018 Feb 5.


Atomic Structure of Type VI Contractile Sheath from Pseudomonas aeruginosa.

Salih O, He S, Planamente S, Stach L, MacDonald JT, Manoli E, Scheres SHW, Filloux A, Freemont PS.

Structure. 2018 Feb 6;26(2):329-336.e3. doi: 10.1016/j.str.2017.12.005. Epub 2018 Jan 4.


Multiple Structures Disclose the Secretins' Secrets.

Filloux A, Voulhoux R.

J Bacteriol. 2018 Feb 7;200(5). pii: e00702-17. doi: 10.1128/JB.00702-17. Print 2018 Mar 1.


Lifestyle transitions and adaptive pathogenesis of Pseudomonas aeruginosa.

Valentini M, Gonzalez D, Mavridou DA, Filloux A.

Curr Opin Microbiol. 2018 Feb;41:15-20. doi: 10.1016/j.mib.2017.11.006. Epub 2017 Dec 19. Review.


Type VI secretion systems in plant-associated bacteria.

Bernal P, Llamas MA, Filloux A.

Environ Microbiol. 2018 Jan;20(1):1-15. doi: 10.1111/1462-2920.13956. Epub 2017 Nov 10. Review.


A Cell-Free Biosensor for Detecting Quorum Sensing Molecules in P. aeruginosa-Infected Respiratory Samples.

Wen KY, Cameron L, Chappell J, Jensen K, Bell DJ, Kelwick R, Kopniczky M, Davies JC, Filloux A, Freemont PS.

ACS Synth Biol. 2017 Dec 15;6(12):2293-2301. doi: 10.1021/acssynbio.7b00219. Epub 2017 Oct 5.


Professor Dieter Haas (1945-2017).

Heeb S, Càmara M, Filloux A, Williams P.

FEMS Microbiol Rev. 2017 Aug 14. doi: 10.1093/femsre/fux040. [Epub ahead of print] No abstract available.


Probing the internal micromechanical properties of Pseudomonas aeruginosa biofilms by Brillouin imaging.

Karampatzakis A, Song CZ, Allsopp LP, Filloux A, Rice SA, Cohen Y, Wohland T, Török P.

NPJ Biofilms Microbiomes. 2017 Sep 8;3:20. doi: 10.1038/s41522-017-0028-z. eCollection 2017.


Contribution of Cyclic di-GMP in the Control of Type III and Type VI Secretion in Pseudomonas aeruginosa.

McCarthy RR, Valentini M, Filloux A.

Methods Mol Biol. 2017;1657:213-224. doi: 10.1007/978-1-4939-7240-1_17.


Current and future therapies for Pseudomonas aeruginosa infection in patients with cystic fibrosis.

Smith WD, Bardin E, Cameron L, Edmondson CL, Farrant KV, Martin I, Murphy RA, Soren O, Turnbull AR, Wierre-Gore N, Alton EW, Bundy JG, Bush A, Connett GJ, Faust SN, Filloux A, Freemont PS, Jones AL, Takats Z, Webb JS, Williams HD, Davies JC.

FEMS Microbiol Lett. 2017 Aug 1;364(14). doi: 10.1093/femsle/fnx121. Review.


A broad range quorum sensing inhibitor working through sRNA inhibition.

Jakobsen TH, Warming AN, Vejborg RM, Moscoso JA, Stegger M, Lorenzen F, Rybtke M, Andersen JB, Petersen R, Andersen PS, Nielsen TE, Tolker-Nielsen T, Filloux A, Ingmer H, Givskov M.

Sci Rep. 2017 Aug 29;7(1):9857. doi: 10.1038/s41598-017-09886-8.


Visualizing Antimicrobials in Bacterial Biofilms: Three-Dimensional Biochemical Imaging Using TOF-SIMS.

Davies SK, Fearn S, Allsopp LP, Harrison F, Ware E, Diggle SP, Filloux A, McPhail DS, Bundy JG.

mSphere. 2017 Jul 19;2(4). pii: e00211-17. doi: 10.1128/mSphere.00211-17. eCollection 2017 Jul-Aug.


RsmA and AmrZ orchestrate the assembly of all three type VI secretion systems in Pseudomonas aeruginosa.

Allsopp LP, Wood TE, Howard SA, Maggiorelli F, Nolan LM, Wettstadt S, Filloux A.

Proc Natl Acad Sci U S A. 2017 Jul 18;114(29):7707-7712. doi: 10.1073/pnas.1700286114. Epub 2017 Jul 3.


A Pseudomonas aeruginosa TIR effector mediates immune evasion by targeting UBAP1 and TLR adaptors.

Imbert PR, Louche A, Luizet JB, Grandjean T, Bigot S, Wood TE, Gagné S, Blanco A, Wunderley L, Terradot L, Woodman P, Garvis S, Filloux A, Guery B, Salcedo SP.

EMBO J. 2017 Jul 3;36(13):1869-1887. doi: 10.15252/embj.201695343. Epub 2017 May 8.


Cyclic-di-GMP regulates lipopolysaccharide modification and contributes to Pseudomonas aeruginosa immune evasion.

McCarthy RR, Mazon-Moya MJ, Moscoso JA, Hao Y, Lam JS, Bordi C, Mostowy S, Filloux A.

Nat Microbiol. 2017 Mar 6;2:17027. doi: 10.1038/nmicrobiol.2017.27.


The pangenome of (Antarctic) Pseudoalteromonas bacteria: evolutionary and functional insights.

Bosi E, Fondi M, Orlandini V, Perrin E, Maida I, de Pascale D, Tutino ML, Parrilli E, Lo Giudice A, Filloux A, Fani R.

BMC Genomics. 2017 Jan 17;18(1):93. doi: 10.1186/s12864-016-3382-y.


The Pseudomonas putida T6SS is a plant warden against phytopathogens.

Bernal P, Allsopp LP, Filloux A, Llamas MA.

ISME J. 2017 Apr;11(4):972-987. doi: 10.1038/ismej.2016.169. Epub 2017 Jan 3.


Correction: The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility.

Valentini M, Laventie BJ, Moscoso JA, Jenal U, Filloux A.

PLoS Genet. 2016 Nov 30;12(11):e1006473. doi: 10.1371/journal.pgen.1006473. eCollection 2016 Nov.


The Diguanylate Cyclase HsbD Intersects with the HptB Regulatory Cascade to Control Pseudomonas aeruginosa Biofilm and Motility.

Valentini M, Laventie BJ, Moscoso J, Jenal U, Filloux A.

PLoS Genet. 2016 Oct 28;12(10):e1006354. doi: 10.1371/journal.pgen.1006354. eCollection 2016 Oct. Erratum in: PLoS Genet. 2016 Nov 30;12 (11):e1006473.


Structural biology: Baseplates in contractile machines.

Filloux A, Freemont P.

Nat Microbiol. 2016 Jun 24;1(7):16104. doi: 10.1038/nmicrobiol.2016.104. No abstract available.


Crystal structure of the CupB6 adhesive tip from the chaperone-usher family of pili from Pseudomonas aeruginosa.

Rasheed M, Garnett J, Pérez-Dorado I, Muhl D, Filloux A, Matthews S.

Biochim Biophys Acta. 2016 Nov;1864(11):1500-5. doi: 10.1016/j.bbapap.2016.07.010. Epub 2016 Jul 29.


TssA forms a gp6-like ring attached to the type VI secretion sheath.

Planamente S, Salih O, Manoli E, Albesa-Jové D, Freemont PS, Filloux A.

EMBO J. 2016 Aug 1;35(15):1613-27. doi: 10.15252/embj.201694024. Epub 2016 Jun 10.


Increased airway glucose increases airway bacterial load in hyperglycaemia.

Gill SK, Hui K, Farne H, Garnett JP, Baines DL, Moore LS, Holmes AH, Filloux A, Tregoning JS.

Sci Rep. 2016 Jun 8;6:27636. doi: 10.1038/srep27636.


The Hybrid Histidine Kinase LadS Forms a Multicomponent Signal Transduction System with the GacS/GacA Two-Component System in Pseudomonas aeruginosa.

Chambonnier G, Roux L, Redelberger D, Fadel F, Filloux A, Sivaneson M, de Bentzmann S, Bordi C.

PLoS Genet. 2016 May 13;12(5):e1006032. doi: 10.1371/journal.pgen.1006032. eCollection 2016 May.


Pseudomonas aeruginosa infection in cystic fibrosis: pathophysiological mechanisms and therapeutic approaches.

Lund-Palau H, Turnbull AR, Bush A, Bardin E, Cameron L, Soren O, Wierre-Gore N, Alton EW, Bundy JG, Connett G, Faust SN, Filloux A, Freemont P, Jones A, Khoo V, Morales S, Murphy R, Pabary R, Simbo A, Schelenz S, Takats Z, Webb J, Williams HD, Davies JC.

Expert Rev Respir Med. 2016 Jun;10(6):685-97. doi: 10.1080/17476348.2016.1177460. Epub 2016 May 13. Review.


Biofilms and Cyclic di-GMP (c-di-GMP) Signaling: Lessons from Pseudomonas aeruginosa and Other Bacteria.

Valentini M, Filloux A.

J Biol Chem. 2016 Jun 10;291(24):12547-55. doi: 10.1074/jbc.R115.711507. Epub 2016 Apr 21. Review.


Type VI secretion and anti-host effectors.

Hachani A, Wood TE, Filloux A.

Curr Opin Microbiol. 2016 Feb;29:81-93. doi: 10.1016/j.mib.2015.11.006. Epub 2015 Dec 24. Review.


Editorial: The many wonders of the bacterial cell surface.

Filloux A, Whitfield C.

FEMS Microbiol Rev. 2016 Mar;40(2):161-3. doi: 10.1093/femsre/fuv047. Epub 2015 Dec 17. No abstract available.


Direct detection of lipid A on intact Gram-negative bacteria by MALDI-TOF mass spectrometry.

Larrouy-Maumus G, Clements A, Filloux A, McCarthy RR, Mostowy S.

J Microbiol Methods. 2016 Jan;120:68-71. doi: 10.1016/j.mimet.2015.12.004. Epub 2015 Dec 3.


Pel is a cationic exopolysaccharide that cross-links extracellular DNA in the Pseudomonas aeruginosa biofilm matrix.

Jennings LK, Storek KM, Ledvina HE, Coulon C, Marmont LS, Sadovskaya I, Secor PR, Tseng BS, Scian M, Filloux A, Wozniak DJ, Howell PL, Parsek MR.

Proc Natl Acad Sci U S A. 2015 Sep 8;112(36):11353-8. doi: 10.1073/pnas.1503058112. Epub 2015 Aug 26.


The absence of the Pseudomonas aeruginosa OprF protein leads to increased biofilm formation through variation in c-di-GMP level.

Bouffartigues E, Moscoso JA, Duchesne R, Rosay T, Fito-Boncompte L, Gicquel G, Maillot O, Bénard M, Bazire A, Brenner-Weiss G, Lesouhaitier O, Lerouge P, Dufour A, Orange N, Feuilloley MG, Overhage J, Filloux A, Chevalier S.

Front Microbiol. 2015 Jun 23;6:630. doi: 10.3389/fmicb.2015.00630. eCollection 2015.


Internalization of Pseudomonas aeruginosa Strain PAO1 into Epithelial Cells Is Promoted by Interaction of a T6SS Effector with the Microtubule Network.

Sana TG, Baumann C, Merdes A, Soscia C, Rattei T, Hachani A, Jones C, Bennett KL, Filloux A, Superti-Furga G, Voulhoux R, Bleves S.

MBio. 2015 Jun 2;6(3):e00712. doi: 10.1128/mBio.00712-15.


Diguanylate cyclase DgcP is involved in plant and human Pseudomonas spp. infections.

Aragon IM, Pérez-Mendoza D, Moscoso JA, Faure E, Guery B, Gallegos MT, Filloux A, Ramos C.

Environ Microbiol. 2015 Nov;17(11):4332-51. doi: 10.1111/1462-2920.12856. Epub 2015 Apr 28.



Filloux A.

FEMS Microbiol Rev. 2015 Jan;39(1):1. doi: 10.1093/femsre/fuu005. No abstract available.


Structure-function analysis reveals that the Pseudomonas aeruginosa Tps4 two-partner secretion system is involved in CupB5 translocation.

Garnett JA, Muhl D, Douse CH, Hui K, Busch A, Omisore A, Yang Y, Simpson P, Marchant J, Waksman G, Matthews S, Filloux A.

Protein Sci. 2015 May;24(5):670-87. doi: 10.1002/pro.2640. Epub 2015 Feb 24.


Coevolution of the ATPase ClpV, the sheath proteins TssB and TssC, and the accessory protein TagJ/HsiE1 distinguishes type VI secretion classes.

Förster A, Planamente S, Manoli E, Lossi NS, Freemont PS, Filloux A.

J Biol Chem. 2014 Nov 21;289(47):33032-43. doi: 10.1074/jbc.M114.600510. Epub 2014 Oct 10.


The diguanylate cyclase SadC is a central player in Gac/Rsm-mediated biofilm formation in Pseudomonas aeruginosa.

Moscoso JA, Jaeger T, Valentini M, Hui K, Jenal U, Filloux A.

J Bacteriol. 2014 Dec;196(23):4081-8. doi: 10.1128/JB.01850-14. Epub 2014 Sep 15.

Supplemental Content

Loading ...
Support Center