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Items: 1 to 50 of 201

1.

Anti-CotH3 antibodies protect mice from mucormycosis by prevention of invasion and augmenting opsonophagocytosis.

Gebremariam T, Alkhazraji S, Soliman SSM, Gu Y, Jeon HH, Zhang L, French SW, Stevens DA, Edwards JE Jr, Filler SG, Uppuluri P, Ibrahim AS.

Sci Adv. 2019 Jun 12;5(6):eaaw1327. doi: 10.1126/sciadv.aaw1327. eCollection 2019 Jun.

PMID:
31206021
2.

Selection of Candida albicans trisomy during oropharyngeal infection results in a commensal-like phenotype.

Forche A, Solis NV, Swidergall M, Thomas R, Guyer A, Beach A, Cromie GA, Le GT, Lowell E, Pavelka N, Berman J, Dudley AM, Selmecki A, Filler SG.

PLoS Genet. 2019 May 15;15(5):e1008137. doi: 10.1371/journal.pgen.1008137. eCollection 2019 May.

3.

CARD9+ microglia promote antifungal immunity via IL-1β- and CXCL1-mediated neutrophil recruitment.

Drummond RA, Swamydas M, Oikonomou V, Zhai B, Dambuza IM, Schaefer BC, Bohrer AC, Mayer-Barber KD, Lira SA, Iwakura Y, Filler SG, Brown GD, Hube B, Naglik JR, Hohl TM, Lionakis MS.

Nat Immunol. 2019 May;20(5):559-570. doi: 10.1038/s41590-019-0377-2. Epub 2019 Apr 17.

PMID:
30996332
4.

AtrR Is an Essential Determinant of Azole Resistance in Aspergillus fumigatus.

Paul S, Stamnes M, Thomas GH, Liu H, Hagiwara D, Gomi K, Filler SG, Moye-Rowley WS.

MBio. 2019 Mar 12;10(2). pii: e02563-18. doi: 10.1128/mBio.02563-18.

5.

Aspergillus endocarditis diagnosed by fungemia plus serum antigen testing.

Hatlen TJ, Filler SG, Bayer A, Shah S, Shodhan S, Van TT.

Med Mycol Case Rep. 2018 Oct 25;23:1-3. doi: 10.1016/j.mmcr.2018.10.004. eCollection 2019 Mar.

6.

Protective immunity in recurrent Staphylococcus aureus infection reflects localized immune signatures and macrophage-conferred memory.

Chan LC, Rossetti M, Miller LS, Filler SG, Johnson CW, Lee HK, Wang H, Gjertson D, Fowler VG Jr, Reed EF, Yeaman MR; MRSA Systems Immunobiology Group.

Proc Natl Acad Sci U S A. 2018 Nov 20;115(47):E11111-E11119. doi: 10.1073/pnas.1808353115. Epub 2018 Oct 8.

7.

Proteome Analysis Reveals the Conidial Surface Protein CcpA Essential for Virulence of the Pathogenic Fungus Aspergillus fumigatus.

Voltersen V, Blango MG, Herrmann S, Schmidt F, Heinekamp T, Strassburger M, Krüger T, Bacher P, Lother J, Weiss E, Hünniger K, Liu H, Hortschansky P, Scheffold A, Löffler J, Krappmann S, Nietzsche S, Kurzai O, Einsele H, Kniemeyer O, Filler SG, Reichard U, Brakhage AA.

MBio. 2018 Oct 2;9(5). pii: e01557-18. doi: 10.1128/mBio.01557-18.

8.

A possible role for fumagillin in cellular damage during host infection by Aspergillus fumigatus.

Guruceaga X, Ezpeleta G, Mayayo E, Sueiro-Olivares M, Abad-Diaz-De-Cerio A, Aguirre Urízar JM, Liu HG, Wiemann P, Bok JW, Filler SG, Keller NP, Hernando FL, Ramirez-Garcia A, Rementeria A.

Virulence. 2018;9(1):1548-1561. doi: 10.1080/21505594.2018.1526528.

9.

Targeted enrichment outperforms other enrichment techniques and enables more multi-species RNA-Seq analyses.

Chung M, Teigen L, Liu H, Libro S, Shetty A, Kumar N, Zhao X, Bromley RE, Tallon LJ, Sadzewicz L, Fraser CM, Rasko DA, Filler SG, Foster JM, Michalski ML, Bruno VM, Dunning Hotopp JC.

Sci Rep. 2018 Sep 6;8(1):13377. doi: 10.1038/s41598-018-31420-7.

10.

Inhibition of EGFR Signaling Protects from Mucormycosis.

Watkins TN, Gebremariam T, Swidergall M, Shetty AC, Graf KT, Alqarihi A, Alkhazraji S, Alsaadi AI, Edwards VL, Filler SG, Ibrahim AS, Bruno VM.

MBio. 2018 Aug 14;9(4). pii: e01384-18. doi: 10.1128/mBio.01384-18.

11.

Intersection of phosphate transport, oxidative stress and TOR signalling in Candida albicans virulence.

Liu NN, Uppuluri P, Broggi A, Besold A, Ryman K, Kambara H, Solis N, Lorenz V, Qi W, Acosta-Zaldívar M, Emami SN, Bao B, An D, Bonilla FA, Sola-Visner M, Filler SG, Luo HR, Engström Y, Ljungdahl PO, Culotta VC, Zanoni I, Lopez-Ribot JL, Köhler JR.

PLoS Pathog. 2018 Jul 30;14(7):e1007076. doi: 10.1371/journal.ppat.1007076. eCollection 2018 Jul.

12.

Functional convergence of gliP and aspf1 in Aspergillus fumigatus pathogenicity.

Liu H, Xu W, Solis NV, Woolford C, Mitchell AP, Filler SG.

Virulence. 2018;9(1):1062-1073. doi: 10.1080/21505594.2018.1482182.

13.

Methodologies for in vitro and in vivo evaluation of efficacy of antifungal and antibiofilm agents and surface coatings against fungal biofilms.

Van Dijck P, Sjollema J, Cammue BP, Lagrou K, Berman J, d'Enfert C, Andes DR, Arendrup MC, Brakhage AA, Calderone R, Cantón E, Coenye T, Cos P, Cowen LE, Edgerton M, Espinel-Ingroff A, Filler SG, Ghannoum M, Gow NAR, Haas H, Jabra-Rizk MA, Johnson EM, Lockhart SR, Lopez-Ribot JL, Maertens J, Munro CA, Nett JE, Nobile CJ, Pfaller MA, Ramage G, Sanglard D, Sanguinetti M, Spriet I, Verweij PE, Warris A, Wauters J, Yeaman MR, Zaat SAJ, Thevissen K.

Microb Cell. 2018 Jun 14;5(7):300-326. doi: 10.15698/mic2018.07.638. Review.

14.

Human Anti-Als3p Antibodies Are Surrogate Markers of NDV-3A Vaccine Efficacy Against Recurrent Vulvovaginal Candidiasis.

Uppuluri P, Singh S, Alqarihi A, Schmidt CS, Hennessey JP Jr, Yeaman MR, Filler SG, Edwards JE, Ibrahim AS.

Front Immunol. 2018 Jun 15;9:1349. doi: 10.3389/fimmu.2018.01349. eCollection 2018.

15.

Author Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

Swidergall M, Solis NV, Lionakis MS, Filler SG.

Nat Microbiol. 2018 Sep;3(9):1074. doi: 10.1038/s41564-018-0188-5.

PMID:
29895959
16.

Candida albicans Cannot Acquire Sufficient Ethanolamine from the Host To Support Virulence in the Absence of De Novo Phosphatidylethanolamine Synthesis.

Davis SE, Tams RN, Solis NV, Wagner AS, Chen T, Jackson JW, Hasim S, Montedonico AE, Dinsmore J, Sparer TE, Filler SG, Reynolds TB.

Infect Immun. 2018 Jul 23;86(8). pii: e00815-17. doi: 10.1128/IAI.00815-17. Print 2018 Aug.

17.

The Hyr1 protein from the fungus Candida albicans is a cross kingdom immunotherapeutic target for Acinetobacter bacterial infection.

Uppuluri P, Lin L, Alqarihi A, Luo G, Youssef EG, Alkhazraji S, Yount NY, Ibrahim BA, Bolaris MA, Edwards JE Jr, Swidergall M, Filler SG, Yeaman MR, Ibrahim AS.

PLoS Pathog. 2018 May 10;14(5):e1007056. doi: 10.1371/journal.ppat.1007056. eCollection 2018 May.

18.

Rapid Phenotypic and Genotypic Diversification After Exposure to the Oral Host Niche in Candida albicans.

Forche A, Cromie G, Gerstein AC, Solis NV, Pisithkul T, Srifa W, Jeffery E, Abbey D, Filler SG, Dudley AM, Berman J.

Genetics. 2018 Jul;209(3):725-741. doi: 10.1534/genetics.118.301019. Epub 2018 May 3.

PMID:
29724862
19.

A Fungal Immunotherapeutic Vaccine (NDV-3A) for Treatment of Recurrent Vulvovaginal Candidiasis-A Phase 2 Randomized, Double-Blind, Placebo-Controlled Trial.

Edwards JE Jr, Schwartz MM, Schmidt CS, Sobel JD, Nyirjesy P, Schodel F, Marchus E, Lizakowski M, DeMontigny EA, Hoeg J, Holmberg T, Cooke MT, Hoover K, Edwards L, Jacobs M, Sussman S, Augenbraun M, Drusano M, Yeaman MR, Ibrahim AS, Filler SG, Hennessey JP Jr.

Clin Infect Dis. 2018 Jun 1;66(12):1928-1936. doi: 10.1093/cid/ciy185.

20.

Candida albicans White-Opaque Switching Influences Virulence but Not Mating during Oropharyngeal Candidiasis.

Solis NV, Park YN, Swidergall M, Daniels KJ, Filler SG, Soll DR.

Infect Immun. 2018 May 22;86(6). pii: e00774-17. doi: 10.1128/IAI.00774-17. Print 2018 Jun.

21.

Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis.

Persichino JG, Can AD, Van TT, Matthews MN, Filler SG.

Med Mycol Case Rep. 2018 Mar 6;21:12-15. doi: 10.1016/j.mmcr.2018.03.004. eCollection 2018 Sep.

22.

Publisher Correction: EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

Swidergall M, Solis NV, Lionakis MS, Filler SG.

Nat Microbiol. 2018 Mar;3(3):387. doi: 10.1038/s41564-017-0100-8.

PMID:
29440749
23.

Comparative transcriptomics of Aspergillus fumigatus strains upon exposure to human airway epithelial cells.

Watkins TN, Liu H, Chung M, Hazen TH, Dunning Hotopp JC, Filler SG, Bruno VM.

Microb Genom. 2018 Feb;4(2). doi: 10.1099/mgen.0.000154. Epub 2018 Jan 18.

24.

Inhibiting mitochondrial phosphate transport as an unexploited antifungal strategy.

McLellan CA, Vincent BM, Solis NV, Lancaster AK, Sullivan LB, Hartland CL, Youngsaye W, Filler SG, Whitesell L, Lindquist S.

Nat Chem Biol. 2018 Feb;14(2):135-141. doi: 10.1038/nchembio.2534. Epub 2017 Dec 11.

25.

EphA2 is an epithelial cell pattern recognition receptor for fungal β-glucans.

Swidergall M, Solis NV, Lionakis MS, Filler SG.

Nat Microbiol. 2018 Jan;3(1):53-61. doi: 10.1038/s41564-017-0059-5. Epub 2017 Nov 13. Erratum in: Nat Microbiol. 2018 Feb 13;:. Nat Microbiol. 2018 Sep;3(9):1074.

26.

Yeast casein kinase 2 governs morphology, biofilm formation, cell wall integrity, and host cell damage of Candida albicans.

Jung SI, Rodriguez N, Irrizary J, Liboro K, Bogarin T, Macias M, Eivers E, Porter E, Filler SG, Park H.

PLoS One. 2017 Nov 6;12(11):e0187721. doi: 10.1371/journal.pone.0187721. eCollection 2017.

27.

Prophylactic Treatment with VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

Gebremariam T, Alkhazraji S, Lin L, Wiederhold NP, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS.

Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e00390-17. doi: 10.1128/AAC.00390-17. Print 2017 Sep.

28.

Microbial glycoside hydrolases as antibiofilm agents with cross-kingdom activity.

Snarr BD, Baker P, Bamford NC, Sato Y, Liu H, Lehoux M, Gravelat FN, Ostapska H, Baistrocchi SR, Cerone RP, Filler EE, Parsek MR, Filler SG, Howell PL, Sheppard DC.

Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7124-7129. doi: 10.1073/pnas.1702798114. Epub 2017 Jun 20.

29.

The Aryl Hydrocarbon Receptor Governs Epithelial Cell Invasion during Oropharyngeal Candidiasis.

Solis NV, Swidergall M, Bruno VM, Gaffen SL, Filler SG.

MBio. 2017 Mar 21;8(2). pii: e00025-17. doi: 10.1128/mBio.00025-17.

30.

Role of Arf GTPases in fungal morphogenesis and virulence.

Labbaoui H, Bogliolo S, Ghugtyal V, Solis NV, Filler SG, Arkowitz RA, Bassilana M.

PLoS Pathog. 2017 Feb 13;13(2):e1006205. doi: 10.1371/journal.ppat.1006205. eCollection 2017 Feb.

31.

The Case for Adopting the "Species Complex" Nomenclature for the Etiologic Agents of Cryptococcosis.

Kwon-Chung KJ, Bennett JE, Wickes BL, Meyer W, Cuomo CA, Wollenburg KR, Bicanic TA, Castañeda E, Chang YC, Chen J, Cogliati M, Dromer F, Ellis D, Filler SG, Fisher MC, Harrison TS, Holland SM, Kohno S, Kronstad JW, Lazera M, Levitz SM, Lionakis MS, May RC, Ngamskulrongroj P, Pappas PG, Perfect JR, Rickerts V, Sorrell TC, Walsh TJ, Williamson PR, Xu J, Zelazny AM, Casadevall A.

mSphere. 2017 Jan 11;2(1). pii: e00357-16. doi: 10.1128/mSphere.00357-16. eCollection 2017 Jan-Feb.

32.

Oropharyngeal Candidiasis: Fungal Invasion and Epithelial Cell Responses.

Swidergall M, Filler SG.

PLoS Pathog. 2017 Jan 12;13(1):e1006056. doi: 10.1371/journal.ppat.1006056. eCollection 2017 Jan. Review. No abstract available.

33.

IL-17 Receptor Signaling in Oral Epithelial Cells Is Critical for Protection against Oropharyngeal Candidiasis.

Conti HR, Bruno VM, Childs EE, Daugherty S, Hunter JP, Mengesha BG, Saevig DL, Hendricks MR, Coleman BM, Brane L, Solis N, Cruz JA, Verma AH, Garg AV, Hise AG, Richardson JP, Naglik JR, Filler SG, Kolls JK, Sinha S, Gaffen SL.

Cell Host Microbe. 2016 Nov 9;20(5):606-617. doi: 10.1016/j.chom.2016.10.001. Epub 2016 Oct 27.

34.

Innate Immune Memory Contributes to Host Defense against Recurrent Skin and Skin Structure Infections Caused by Methicillin-Resistant Staphylococcus aureus.

Chan LC, Chaili S, Filler SG, Miller LS, Solis NV, Wang H, Johnson CW, Lee HK, Diaz LF, Yeaman MR.

Infect Immun. 2017 Jan 26;85(2). pii: e00876-16. doi: 10.1128/IAI.00876-16. Print 2017 Feb.

35.

Aspergillus fumigatus CalA binds to integrin α5β1 and mediates host cell invasion.

Liu H, Lee MJ, Solis NV, Phan QT, Swidergall M, Ralph B, Ibrahim AS, Sheppard DC, Filler SG.

Nat Microbiol. 2016 Nov 14;2:16211. doi: 10.1038/nmicrobiol.2016.211.

36.

Cryptococcus gattii Meningitis Complicated by Listeria monocytogenes Infection.

Deiss RG, Bolaris M, Wang A, Filler SG.

Emerg Infect Dis. 2016 Sep;22(9):1669-71. doi: 10.3201/eid2209.160142. No abstract available.

37.

An integrated genomic and transcriptomic survey of mucormycosis-causing fungi.

Chibucos MC, Soliman S, Gebremariam T, Lee H, Daugherty S, Orvis J, Shetty AC, Crabtree J, Hazen TH, Etienne KA, Kumari P, O'Connor TD, Rasko DA, Filler SG, Fraser CM, Lockhart SR, Skory CD, Ibrahim AS, Bruno VM.

Nat Commun. 2016 Jul 22;7:12218. doi: 10.1038/ncomms12218.

38.

Bicarbonate correction of ketoacidosis alters host-pathogen interactions and alleviates mucormycosis.

Gebremariam T, Lin L, Liu M, Kontoyiannis DP, French S, Edwards JE Jr, Filler SG, Ibrahim AS.

J Clin Invest. 2016 Jun 1;126(6):2280-94. doi: 10.1172/JCI82744. Epub 2016 May 9.

39.

Deacetylation of Fungal Exopolysaccharide Mediates Adhesion and Biofilm Formation.

Lee MJ, Geller AM, Bamford NC, Liu H, Gravelat FN, Snarr BD, Le Mauff F, Chabot J, Ralph B, Ostapska H, Lehoux M, Cerone RP, Baptista SD, Vinogradov E, Stajich JE, Filler SG, Howell PL, Sheppard DC.

MBio. 2016 Apr 5;7(2):e00252-16. doi: 10.1128/mBio.00252-16.

40.

Gene Expression Profiling of Infecting Microbes Using a Digital Bar-coding Platform.

Xu W, Solis NV, Filler SG, Mitchell AP.

J Vis Exp. 2016 Jan 13;(107):e53460. doi: 10.3791/53460.

41.

The Fungal Exopolysaccharide Galactosaminogalactan Mediates Virulence by Enhancing Resistance to Neutrophil Extracellular Traps.

Lee MJ, Liu H, Barker BM, Snarr BD, Gravelat FN, Al Abdallah Q, Gavino C, Baistrocchi SR, Ostapska H, Xiao T, Ralph B, Solis NV, Lehoux M, Baptista SD, Thammahong A, Cerone RP, Kaminskyj SG, Guiot MC, Latgé JP, Fontaine T, Vinh DC, Filler SG, Sheppard DC.

PLoS Pathog. 2015 Oct 22;11(10):e1005187. doi: 10.1371/journal.ppat.1005187. eCollection 2015 Oct.

42.

Pathogen Gene Expression Profiling During Infection Using a Nanostring nCounter Platform.

Xu W, Solis NV, Filler SG, Mitchell AP.

Methods Mol Biol. 2016;1361:57-65. doi: 10.1007/978-1-4939-3079-1_3.

43.

VT-1161 Protects Immunosuppressed Mice from Rhizopus arrhizus var. arrhizus Infection.

Gebremariam T, Wiederhold NP, Fothergill AW, Garvey EP, Hoekstra WJ, Schotzinger RJ, Patterson TF, Filler SG, Ibrahim AS.

Antimicrob Agents Chemother. 2015 Dec;59(12):7815-7. doi: 10.1128/AAC.01437-15. Epub 2015 Sep 14.

44.

Nonredundant Roles of Interleukin-17A (IL-17A) and IL-22 in Murine Host Defense against Cutaneous and Hematogenous Infection Due to Methicillin-Resistant Staphylococcus aureus.

Chan LC, Chaili S, Filler SG, Barr K, Wang H, Kupferwasser D, Edwards JE Jr, Xiong YQ, Ibrahim AS, Miller LS, Schmidt CS, Hennessey JP Jr, Yeaman MR.

Infect Immun. 2015 Nov;83(11):4427-37. doi: 10.1128/IAI.01061-15. Epub 2015 Sep 8.

45.

Candida albicans cell shaving uncovers new proteins involved in cell wall integrity, yeast to hypha transition, stress response and host-pathogen interaction.

Gil-Bona A, Parra-Giraldo CM, Hernáez ML, Reales-Calderon JA, Solis NV, Filler SG, Monteoliva L, Gil C.

J Proteomics. 2015 Sep 8;127(Pt B):340-351. doi: 10.1016/j.jprot.2015.06.006. Epub 2015 Jun 15.

46.

Correction: The pH-Responsive PacC Transcription Factor of Aspergillus fumigatus Governs Epithelial Entry and Tissue Invasion during Pulmonary Aspergillosis.

Bertuzzi M, Schrettl M, Alcazar-Fuoli L, Cairns TC, Muñoz A, Walker LA, Herbst S, Safari M, Cheverton AM, Chen D, Liu H, Saijo S, Fedorova ND, Armstrong-James D, Munro CA, Read ND, Filler SG, Espeso EA, Nierman WC, Haas H, Bignell EM.

PLoS Pathog. 2015 Jun 18;11(6):e1004943. doi: 10.1371/journal.ppat.1004943. eCollection 2015 Jun. No abstract available.

47.

New signaling pathways govern the host response to C. albicans infection in various niches.

Liu Y, Shetty AC, Schwartz JA, Bradford LL, Xu W, Phan QT, Kumari P, Mahurkar A, Mitchell AP, Ravel J, Fraser CM, Filler SG, Bruno VM.

Genome Res. 2015 May;25(5):679-89. doi: 10.1101/gr.187427.114. Epub 2015 Apr 9.

48.

Activation and alliance of regulatory pathways in C. albicans during mammalian infection.

Xu W, Solis NV, Ehrlich RL, Woolford CA, Filler SG, Mitchell AP.

PLoS Biol. 2015 Feb 18;13(2):e1002076. doi: 10.1371/journal.pbio.1002076. eCollection 2015 Feb.

49.

Using Bayesian modelling to investigate factors governing antibiotic-induced Candida albicans colonization of the GI tract.

Shankar J, Solis NV, Mounaud S, Szpakowski S, Liu H, Losada L, Nierman WC, Filler SG.

Sci Rep. 2015 Feb 3;5:8131. doi: 10.1038/srep08131.

50.

A systematic evaluation of high-dimensional, ensemble-based regression for exploring large model spaces in microbiome analyses.

Shankar J, Szpakowski S, Solis NV, Mounaud S, Liu H, Losada L, Nierman WC, Filler SG.

BMC Bioinformatics. 2015 Feb 1;16:31. doi: 10.1186/s12859-015-0467-6.

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