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Items: 1 to 50 of 172

1.

Elisa Izaurralde (1959-2018).

Conti E, Filipowicz W.

RNA. 2018 Aug;24(8):ix-x. doi: 10.1261/rna.067397.118. Epub 2018 May 24. No abstract available.

2.

Traversing the RNA world.

Filipowicz W.

J Biol Chem. 2017 May 19;292(20):8122-8135. doi: 10.1074/jbc.X117.789065. Epub 2017 Apr 5.

3.

RNA 3'-terminal phosphate cyclases and cyclase-like proteins.

Filipowicz W.

Postepy Biochem. 2016;62(3):327-334. Review.

4.

Structure of a Human 4E-T/DDX6/CNOT1 Complex Reveals the Different Interplay of DDX6-Binding Proteins with the CCR4-NOT Complex.

Ozgur S, Basquin J, Kamenska A, Filipowicz W, Standart N, Conti E.

Cell Rep. 2015 Oct 27;13(4):703-711. doi: 10.1016/j.celrep.2015.09.033. Epub 2015 Oct 17.

5.

A network comprising short and long noncoding RNAs and RNA helicase controls mouse retina architecture.

Krol J, Krol I, Alvarez CP, Fiscella M, Hierlemann A, Roska B, Filipowicz W.

Nat Commun. 2015 Jun 4;6:7305. doi: 10.1038/ncomms8305.

6.

The long unfinished march towards understanding microRNA-mediated repression.

Filipowicz W, Sonenberg N.

RNA. 2015 Apr;21(4):519-24. doi: 10.1261/rna.051219.115. No abstract available.

7.

Potent degradation of neuronal miRNAs induced by highly complementary targets.

de la Mata M, Gaidatzis D, Vitanescu M, Stadler MB, Wentzel C, Scheiffele P, Filipowicz W, Großhans H.

EMBO Rep. 2015 Apr;16(4):500-11. doi: 10.15252/embr.201540078. Epub 2015 Feb 27.

8.

Making ends meet: a role of RNA ligase RTCB in unfolded protein response.

Filipowicz W.

EMBO J. 2014 Dec 17;33(24):2887-9. doi: 10.15252/embj.201490425. Epub 2014 Nov 17. No abstract available.

9.

miRNAs 182 and 183 are necessary to maintain adult cone photoreceptor outer segments and visual function.

Busskamp V, Krol J, Nelidova D, Daum J, Szikra T, Tsuda B, Jüttner J, Farrow K, Scherf BG, Alvarez CP, Genoud C, Sothilingam V, Tanimoto N, Stadler M, Seeliger M, Stoffel M, Filipowicz W, Roska B.

Neuron. 2014 Aug 6;83(3):586-600. doi: 10.1016/j.neuron.2014.06.020. Epub 2014 Jul 4.

10.

Structural and biochemical insights to the role of the CCR4-NOT complex and DDX6 ATPase in microRNA repression.

Mathys H, Basquin J, Ozgur S, Czarnocki-Cieciura M, Bonneau F, Aartse A, Dziembowski A, Nowotny M, Conti E, Filipowicz W.

Mol Cell. 2014 Jun 5;54(5):751-65. doi: 10.1016/j.molcel.2014.03.036. Epub 2014 Apr 24.

11.

The double-stranded RNA binding domain of human Dicer functions as a nuclear localization signal.

Doyle M, Badertscher L, Jaskiewicz L, Güttinger S, Jurado S, Hugenschmidt T, Kutay U, Filipowicz W.

RNA. 2013 Sep;19(9):1238-52. doi: 10.1261/rna.039255.113. Epub 2013 Jul 23.

12.

The mammalian TRIM-NHL protein TRIM71/LIN-41 is a repressor of mRNA function.

Loedige I, Gaidatzis D, Sack R, Meister G, Filipowicz W.

Nucleic Acids Res. 2013 Jan 7;41(1):518-32. doi: 10.1093/nar/gks1032. Epub 2012 Nov 3.

13.

Retrospective. Aaron Shatkin (1934-2012).

Sonenberg N, Filipowicz W.

Science. 2012 Jul 20;337(6092):309. doi: 10.1126/science.1226820. No abstract available.

PMID:
22822142
14.

Kinetic analysis reveals successive steps leading to miRNA-mediated silencing in mammalian cells.

Béthune J, Artus-Revel CG, Filipowicz W.

EMBO Rep. 2012 Aug;13(8):716-23. doi: 10.1038/embor.2012.82. Epub 2012 Jun 8.

15.

HuR protein attenuates miRNA-mediated repression by promoting miRISC dissociation from the target RNA.

Kundu P, Fabian MR, Sonenberg N, Bhattacharyya SN, Filipowicz W.

Nucleic Acids Res. 2012 Jun;40(11):5088-100. doi: 10.1093/nar/gks148. Epub 2012 Feb 23.

16.

miRNA repression involves GW182-mediated recruitment of CCR4-NOT through conserved W-containing motifs.

Chekulaeva M, Mathys H, Zipprich JT, Attig J, Colic M, Parker R, Filipowicz W.

Nat Struct Mol Biol. 2011 Oct 7;18(11):1218-26. doi: 10.1038/nsmb.2166.

17.

dsRNA expression in the mouse elicits RNAi in oocytes and low adenosine deamination in somatic cells.

Nejepinska J, Malik R, Filkowski J, Flemr M, Filipowicz W, Svoboda P.

Nucleic Acids Res. 2012 Jan;40(1):399-413. doi: 10.1093/nar/gkr702. Epub 2011 Sep 8.

18.

Properties of the Regulatory RNA-Binding Protein HuR and its Role in Controlling miRNA Repression.

Meisner NC, Filipowicz W.

Adv Exp Med Biol. 2011;700:106-23. doi: 10.1007/978-1-4419-7823-3_10. Review.

PMID:
21755477
19.

KSRP Promotes the Maturation of a Group of miRNA Precuresors.

Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.

Adv Exp Med Biol. 2011;700:36-42. doi: 10.1007/978-1-4419-7823-3_4.

PMID:
21755471
20.

Twenty-second annual Pezcoller Symposium: RNA biology and cancer.

Bernards R, Filipowicz W, Livingston DM, Mihich E.

Cancer Res. 2010 Dec 15;70(24):10034-7. doi: 10.1158/0008-5472.CAN-10-2978.

21.

The liver-specific microRNA miR-122: biology and therapeutic potential.

Filipowicz W, Grosshans H.

Prog Drug Res. 2011;67:221-38. Review.

PMID:
21141732
22.

Dicer is associated with ribosomal DNA chromatin in mammalian cells.

Sinkkonen L, Hugenschmidt T, Filipowicz W, Svoboda P.

PLoS One. 2010 Aug 13;5(8):e12175. doi: 10.1371/journal.pone.0012175.

23.

The widespread regulation of microRNA biogenesis, function and decay.

Krol J, Loedige I, Filipowicz W.

Nat Rev Genet. 2010 Sep;11(9):597-610. doi: 10.1038/nrg2843. Epub 2010 Jul 27. Review.

PMID:
20661255
24.

Regulation of mRNA translation and stability by microRNAs.

Fabian MR, Sonenberg N, Filipowicz W.

Annu Rev Biochem. 2010;79:351-79. doi: 10.1146/annurev-biochem-060308-103103. Review.

PMID:
20533884
25.

The GW/WG repeats of Drosophila GW182 function as effector motifs for miRNA-mediated repression.

Chekulaeva M, Parker R, Filipowicz W.

Nucleic Acids Res. 2010 Oct;38(19):6673-83. doi: 10.1093/nar/gkq501. Epub 2010 Jun 8.

26.

Characterizing light-regulated retinal microRNAs reveals rapid turnover as a common property of neuronal microRNAs.

Krol J, Busskamp V, Markiewicz I, Stadler MB, Ribi S, Richter J, Duebel J, Bicker S, Fehling HJ, Schübeler D, Oertner TG, Schratt G, Bibel M, Roska B, Filipowicz W.

Cell. 2010 May 14;141(4):618-31. doi: 10.1016/j.cell.2010.03.039.

27.

Properties of the regulatory RNA-binding protein HuR and its role in controlling miRNA repression.

Meisner NC, Filipowicz W.

Adv Exp Med Biol. 2010;700:106-23. Review.

PMID:
21627034
28.

KSRP promotes the maturation of a group of miRNA precursors.

Trabucchi M, Briata P, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.

Adv Exp Med Biol. 2010;700:36-42.

29.

How to control miRNA maturation?

Trabucchi M, Briata P, Filipowicz W, Rosenfeld MG, Ramos A, Gherzi R.

RNA Biol. 2009 Nov-Dec;6(5):536-40. Review.

PMID:
19875945
30.

Mammalian miRNA RISC recruits CAF1 and PABP to affect PABP-dependent deadenylation.

Fabian MR, Mathonnet G, Sundermeier T, Mathys H, Zipprich JT, Svitkin YV, Rivas F, Jinek M, Wohlschlegel J, Doudna JA, Chen CY, Shyu AB, Yates JR 3rd, Hannon GJ, Filipowicz W, Duchaine TF, Sonenberg N.

Mol Cell. 2009 Sep 24;35(6):868-80. doi: 10.1016/j.molcel.2009.08.004. Epub 2009 Aug 27.

31.

The RNA-binding protein KSRP promotes the biogenesis of a subset of microRNAs.

Trabucchi M, Briata P, Garcia-Mayoral M, Haase AD, Filipowicz W, Ramos A, Gherzi R, Rosenfeld MG.

Nature. 2009 Jun 18;459(7249):1010-4. doi: 10.1038/nature08025. Epub 2009 May 20.

32.

Mechanisms of miRNA-mediated post-transcriptional regulation in animal cells.

Chekulaeva M, Filipowicz W.

Curr Opin Cell Biol. 2009 Jun;21(3):452-60. doi: 10.1016/j.ceb.2009.04.009. Epub 2009 May 18. Review.

PMID:
19450959
33.

Importance of the C-terminal domain of the human GW182 protein TNRC6C for translational repression.

Zipprich JT, Bhattacharyya S, Mathys H, Filipowicz W.

RNA. 2009 May;15(5):781-93. doi: 10.1261/rna.1448009. Epub 2009 Mar 20.

34.

Multiple independent domains of dGW182 function in miRNA-mediated repression in Drosophila.

Chekulaeva M, Filipowicz W, Parker R.

RNA. 2009 May;15(5):794-803. doi: 10.1261/rna.1364909. Epub 2009 Mar 20.

35.

TRIM-NHL proteins take on miRNA regulation.

Loedige I, Filipowicz W.

Cell. 2009 Mar 6;136(5):818-20. doi: 10.1016/j.cell.2009.02.030.

36.

Decreased levels of microRNA miR-122 in individuals with hepatitis C responding poorly to interferon therapy.

Sarasin-Filipowicz M, Krol J, Markiewicz I, Heim MH, Filipowicz W.

Nat Med. 2009 Jan;15(1):31-3. doi: 10.1038/nm.1902. Epub 2009 Jan 4.

PMID:
19122656
37.

Dendrites of mammalian neurons contain specialized P-body-like structures that respond to neuronal activation.

Cougot N, Bhattacharyya SN, Tapia-Arancibia L, Bordonné R, Filipowicz W, Bertrand E, Rage F.

J Neurosci. 2008 Dec 17;28(51):13793-804. doi: 10.1523/JNEUROSCI.4155-08.2008.

38.

Proteomics joins the search for microRNA targets.

Grosshans H, Filipowicz W.

Cell. 2008 Aug 22;134(4):560-2. doi: 10.1016/j.cell.2008.08.008.

39.

Interferon signaling and treatment outcome in chronic hepatitis C.

Sarasin-Filipowicz M, Oakeley EJ, Duong FH, Christen V, Terracciano L, Filipowicz W, Heim MH.

Proc Natl Acad Sci U S A. 2008 May 13;105(19):7034-9. doi: 10.1073/pnas.0707882105. Epub 2008 May 8.

40.

MicroRNAs control de novo DNA methylation through regulation of transcriptional repressors in mouse embryonic stem cells.

Sinkkonen L, Hugenschmidt T, Berninger P, Gaidatzis D, Mohn F, Artus-Revel CG, Zavolan M, Svoboda P, Filipowicz W.

Nat Struct Mol Biol. 2008 Mar;15(3):259-67. doi: 10.1038/nsmb.1391. Epub 2008 Mar 2.

PMID:
18311153
41.

Role of Dicer in posttranscriptional RNA silencing.

Jaskiewicz L, Filipowicz W.

Curr Top Microbiol Immunol. 2008;320:77-97. Review.

PMID:
18268840
42.

Molecular biology: the expanding world of small RNAs.

Grosshans H, Filipowicz W.

Nature. 2008 Jan 24;451(7177):414-6. doi: 10.1038/451414a. No abstract available.

PMID:
18216846
43.

Mechanisms of post-transcriptional regulation by microRNAs: are the answers in sight?

Filipowicz W, Bhattacharyya SN, Sonenberg N.

Nat Rev Genet. 2008 Feb;9(2):102-14. doi: 10.1038/nrg2290. Review.

PMID:
18197166
44.

MicroRNA inhibition of translation initiation in vitro by targeting the cap-binding complex eIF4F.

Mathonnet G, Fabian MR, Svitkin YV, Parsyan A, Huck L, Murata T, Biffo S, Merrick WC, Darzynkiewicz E, Pillai RS, Filipowicz W, Duchaine TF, Sonenberg N.

Science. 2007 Sep 21;317(5845):1764-7. Epub 2007 Jul 26.

45.

Argonautes and company: sailing against the wind.

Bhattacharyya SN, Filipowicz W.

Cell. 2007 Mar 23;128(6):1027-8.

46.

Stress-induced reversal of microRNA repression and mRNA P-body localization in human cells.

Bhattacharyya SN, Habermacher R, Martine U, Closs EI, Filipowicz W.

Cold Spring Harb Symp Quant Biol. 2006;71:513-21. Review.

PMID:
17381334
47.

A novel microarray approach reveals new tissue-specific signatures of known and predicted mammalian microRNAs.

Beuvink I, Kolb FA, Budach W, Garnier A, Lange J, Natt F, Dengler U, Hall J, Filipowicz W, Weiler J.

Nucleic Acids Res. 2007;35(7):e52. Epub 2007 Mar 13.

48.

Repression of protein synthesis by miRNAs: how many mechanisms?

Pillai RS, Bhattacharyya SN, Filipowicz W.

Trends Cell Biol. 2007 Mar;17(3):118-26. Epub 2007 Jan 2. Review.

PMID:
17197185
49.

ADP-ribose-1"-phosphatase activities of the human coronavirus 229E and SARS coronavirus X domains.

Putics A, Slaby J, Filipowicz W, Gorbalenya AE, Ziebuhr J.

Adv Exp Med Biol. 2006;581:93-6. No abstract available.

PMID:
17037511
50.

Effects of Dicer and Argonaute down-regulation on mRNA levels in human HEK293 cells.

Schmitter D, Filkowski J, Sewer A, Pillai RS, Oakeley EJ, Zavolan M, Svoboda P, Filipowicz W.

Nucleic Acids Res. 2006;34(17):4801-15. Epub 2006 Sep 13.

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